International Journal of Environmental Research and Public Health
·
2016
·Vol. 13
·期 9
·925
·
IF 2.035
Hong-Qin Sun,Yang Du,Zi-Yang Zhang,Wen-Jing Jiang,Yan-Min Guo,Xi-Wu Lu,Yi-Min Zhang,Li-Wei Sun
Benzophenone (BP) andN,N-diethyl-3-methylbenzamide (DEET) are two chemicals often used in personal care products (PCPs). There is a lack of systematic ecotoxicological evaluations about the two chemicals to aquatic organisms. In the present study, the acute toxic effects onChlorella vulgaris,Daphnia Magana, andBrachydanio reriowere tested and the ecotoxicological risks were evaluated. For BP, the 96-h half-maximal effective concentration (EC50) onC. vulgariswas 6.86 mg/L; the 24-h median lethal concentration (LC50) onD. maganawas 7.63 mg/L; the 96-h LC50onB. reriowas 14.73 mg/L. For DEET, those were 270.72 mg/L, 40.74 mg/L, and 109.67 mg/L, respectively. The mixture toxicity of BP and DEET, onC. vulgaris,D. magana, andB. rerioall showed an additive effect. The induced predicted no-effect concentrations (PNECs) for BP and DEET by assessment factor (AF) method are 0.003 mg/L and 0.407 mg/L, respectively. Both are lower than the concentrations detected from environment at present, verifying that BP and DEET are low-risk chemicals to the environment.
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MEDICINAL CHEMISTRY RESEARCH
·
2019
·Vol. 28
·期 9
·1388-1401
·
IF 1.72
Chen Xin,Liu Xiujie,Qiu kai,Xu Xiang,Li Caiwen,Wang Yan
According to the bio-isosterism theory, a series of N , N ’-disubstitutedphenyl-4-ethoxylbenzene-1, 3-disulfonamides ( 5a - p ) were designed and synthesized by two steps of reactions including chlorosulfonation and ammonolysis. The structures of all compounds have been confirmed by IR, 1 H-NMR, 13 C-NMR, and ESI-MS spectra. The in vitro anti-platelet aggregation activities were evaluated by Born’s test induced by adenosine diphosphate (ADP) and arachidonic acid (AA), respectively. The biological evaluation results revealed that compound 5h had the lowest IC 50 value (0.32 μM) and the highest inhibition rate (40.9 %) that of three positive control agents clopidogrel (0.41 μM, 23.5 %), aspirin (0.53 μM, 28.9 %), and picotamide (0.76 μM, 32.7 %). Afterwards, compounds with higher activities were selected to further study in vitro cytotoxicity via cell counting kit-8 (CCK-8) assay. The cytotoxicity results indicated that compound 5h had simultaneously the lowest cytotoxicity, while other compounds had no significant relationship between the anti-platelet activities and cytotoxicities. Based on above in vitro anti-platelet activity data, the SAR (Structure Activity Relationship) of the target compounds was preliminarily summarized. In general, N , N ’-disubstitutedphenyl-4-ethoxylbenzene-1, 3-disulfonamides have the potential of further study and very likely become safer and more effective anti-platelet agents.
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JOURNAL OF ORGANIC CHEMISTRY
·
2024
·
IF 3.3
Jin Yan,Suijie Zhong,Xu Chen,Yihuan Luo,Hua Cao,Xiang Liu,Limin Zhao
Here, we report controlled and site-selective C–H alkenylation and dialkenylation of indolizines and pyrrolo[1,2-a]quinolines with β-alkoxyvinyl trifluoromethylketones under simple and practical conditions. Moreover, this direct C–H alkenylation strategy can also be extended to imidazo[1,2-a]pyridines. Notably, without a transition metal and external oxidant, efficient dehydrogenative β-alkenylation of tertiary amines with β-alkoxyvinyl trifluoromethylketones is presented.
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CHEMICAL ENGINEERING RESEARCH & DESIGN
·
2018
·
IF 2.795
Mengjie Sun,Meng Li,Pin Wang,Xu Zhang,Cuiming Wu,Yonghui Wu
Anion exchange membranes are prepared by phase inversion of P84 co -polyimide to obtain porous structure, and then chemically modified by branched polyethylenimine. The porous membranes are compared with a dense P84 membrane. The dense membrane is hydrophobic with large area resistance (>85 Ω cm 2 ), while the porous membranes are hydrophilic with low area resistance (2.4–3.5 Ω cm 2 ), lower than that of commercial membrane CJMA-3 (6.0 Ω cm 2 ). The ion exchange capacities are in the range of 0.83–0.86 mmol/g and the water uptake values are 90–130%, both of which are higher than those of dense P84 membrane and CJMA-3 membrane (0.5–0.6 mmol/g; 15–20%). The P84 co -polyimide membranes are utilized in bipolar membrane electrodialysis (BMED) process to produce N -2-hydroxyethylpiperazine- N ′-2-ethanesulfonic acid (HEPES). The porous membranes can decrease the transport resistance of HEPES − ions and yield high recovery ratio and current efficiency, while the dense membrane is unsuitable for BMED . The output of HEPES is increased significantly if the membranes have finger- or tear-like pores, as well as higher ion exchange capacity. The HEPES − recovery ratios are 52.3–61.6% after running 6 h under 40 V, which are higher than that of membrane CJMA-3 (46.5%). The current efficiency can reach up to 86.1% and the energy consumption is only 3.92 kWh/kg by using the optimal porous membrane M-1, which are better than membrane CJMA-3 (65.5%, 5.15 kWh/kg). Hence, the porous membranes have high potential for producing organic acid with high molecular weight.
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IEEE ELECTRON DEVICE LETTERS
·
2023
·Vol. 44
·期 7
·1152-1155
·
IF 4.9
Weishuai Duan,Zhe Liu,Xinfa Zhu,Biao He,Chao Fan,Yonghui Zhang,Mengjun Wang,Hongxing Zheng,Erping Li
Near-ultraviolet (NUV) detectors based on two-dimensional (2D) materials have garnered considerable attention owing to their atomic-scale thickness, varied bandgap, and strong interaction with incident light. In this work, homostructures composed of tin disulfide/chromium–doped tin disulfide (SnS
2
/Cr–SnS
2
) were proposed for 405 nm near-ultraviolet detectors. Afterward, superlative detectors were fabricated through the employment of micro-mechanical exfoliation and polydimethylsiloxane-assisted dry-transfer methods, anchored by the SnS
2
Cr–SnS
2
homostructures. The detectors demonstrated exceptional detection performance for 405 nm NUV radiation with a significant responsivity of
$2.04\times 10^{{3}}\,\,\text {A}\cdot \text {W}^{-{1}}$
and a short response time of 8 ms, exceeding that of detectors based on most 2D materials and even commercial light detectors (Thorlabs FD11A–Si). The work presents an effective homostructure for high-performance SnS
2
-based detectors, thereby opening an opportunity for the utilization of SnS
2
in NUV detectors.
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JOURNAL OF CHEMICAL THERMODYNAMICS
·
2020
·
IF 2.888
Taotao Zhan,Yuqi Su,Ying Zhang,Xiangyang Liu,Maogang He
The mutual diffusion coefficients of ethanol + n-heptane and diethyl carbonate (DEC) + n-heptane binary solutions were measured over the mass fraction from 0.05 to 0.95 at the pressure of 0.101 MPa, and at temperatures T = 288.15 K, 298.15 K, 308.15 K and 318.15 K. The expanded relative uncertainty ( k = 2) of the Mach-Zehnder digital holographic interferometry employed in the measurements was estimated to be less than 2.4% with the confidence level of 0.95. A semi-empirical correlation was used to fit the mutual diffusion coefficients as a function of concentration and temperature, which represents the experimental values with the absolute average relative deviations being 0.94% for ethanol + n-heptane and 0.90% for DEC + n-heptane. The temperature and concentration dependences of the mutual diffusion coefficients were investigated. The strongest non-ideal thermodynamic behaviors appear when the mass fraction of ethanol is within the limits of 0.45 to 0.65 or that of DEC is within the limits of 0.45 to 0.65. Besides, the mutual diffusion coefficients of ethanol + n-heptane and DEC + n-heptane binary solutions are found to be extremely sensitive to the solute concentration over the mass fraction of ethanol and DEC from 0.00 to 0.05, respectively.
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POLYMER SCIENCE SERIES A
·
2018
·Vol. 60
·期 5
·612-617
·
IF 0.729
Wang Jinjing,Wang Huifeng,Li Yan,Tian Li,Chen Shanmin,Liu Qiang,Guo Zhen
A novel copolymer surfactant has been prepared via a free radical copolymerization of CO 2 -switchable monomer N , N -diethylaminoethyl methacrylate and the hydrophilic monomer sodium vinyl-sulfonate and characterized. The results of conductivity, dynamic light scattering and cryogenic transmission electron microscopy study showed the change of the microstructure of copolymer in water by adding or removing of CO 2 . The copolymer aqueous solution was found to exhibit reversible switchability by the bubbling of CO 2 /N 2 .
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CARBOHYDRATE POLYMERS
·
2012
·
IF 3.628
Ke Zhang,Zhengke Wang,Youliang Li,Zhiqiang Jiang,Qiaoling Hu,Minying Liu,Qingxiang Zhao
In order to develop stimuli-responsive hydrogel, chitosan graft copolymer with chitosan back-bone and poly( N -isopropylacrylamide)- block -poly(acrylic acid) (PNIPAAm- b -PAA) branch chains was prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization in DMF. The chain transfer agent was obtained by modification of chitosan with 3-benzylsulfanyl thiocarbonylsulfanyl propionic acid (BPATT) with 68% the degree of substitute. The graft polymerizations possessed controlled/living characteristics. The behavior of the graft copolymer in aqueous solution was investigated by dynamic light scattering, transmission electron microscopy, and UV-visible spectrophotometer. N -Phthaloylchitosan- graft -(poly( N -isopropylacrylamide)- block -poly(acrylic acid)) copolymer ( N -phthaloylchitosan- g -(PNIPAAm- b -PAA)) could assemble to micelles in aqueous solution in range of 200–300 nm with narrow size distribution, and the hydrodynamic diameter could be controlled dependent on length of branch chains and temperature. The LCST values of micelle could be modulated from 34 to 40 °C by controlling the constitution of branch chains, pH, and concentration.
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DESALINATION
·
2025
·
IF 9.8
Minfu Mo,Yaling Lin,Danni Lin,Xiaojuan Ma,Yubin Hong,Lihui Chen,Dong Wang,Liulian Huang
Cellulose acetate (CA) has attracted much attention in the preparation of ultrafiltration membranes due to its green and sustainable characteristics. However, its poor performance (separation and antifouling performance, etc.) limits the application of CA-based membranes in water treatment. In this work, we prepared a cellulose acetate ultrafiltration membrane with enhanced separation performance by enhancing the dissolution process of CA. The dissolution process of CA was controlled by adjusting the ratio of mixed solvent ( N , N -dimethylacetamide (DMAC) and N -methyl pyrrolidone (NMP)), which could tune the phase conversion rate, optimizing the pore structures of the membranes. Compared to the single solvent (M0, M8), the optimal membrane (M4) exhibited a finger-like pore structure and the lowest surface roughness, which was favorable for achieving high water flux. As a result, the M4 possessed a comparable pure water flux (335.8 L·m −2 h −1 ) which was higher than M0 (1.8 times) and M8 (1.7 times), while the BSA rejection rate reached 96.4 %. Besides, the M4 showed a stable separation performance in different operation pressures, BSA concentration, and long-term experiments. This work provided a new method for the preparation of cellulose acetate ultrafiltration membrane with good separation performance and anti-fouling performance and also provides a new way for water treatment.
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产品关联
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高影响因子
DALTON TRANSACTIONS
·
2021
·Vol. 50
·期 29
·10206-10213
·
IF 4.39
Wenyao Zhang,Wenqi Jin,Meng Cheng,Ruonan Zhang,Zhihua Yang,Shilie Pan
Fluorine-containing compounds significantly enrich the diversity of inorganic chemical structures. Here, four alkaline-earth metal difluorophosphates with different space groups, namely NH4Mg(PO2F2)3 (Cmcm) (1), NH4Sr(PO2F2)3 (P) (2), (NH4)2Ba(PO2F2)4 (P2/n) (3) and Ba(PO2F2)2 (I2d) (4), were synthesized and their structures were determined for the first time. 4 is not only the first alkaline-earth-metal difluorophosphate, but also the first difluorophosphate reported to crystallize in the non-centrosymmetric space group I2d of the tetragonal crystal system. All of the three-dimensional (3D) structures of the title compounds consist of isolated (PO2F2)−, AE–O and NH4+ units, while the differences of the cation radius result in various arrangements of the (PO2F2)− units, which leads to diverse crystal structures and the disparate optical anisotropy of the crystals. According to the deep-ultraviolet (DUV) transmittance spectrum, 3 exhibits a short DUV cut off edge (<180 nm). Solid state 19F and 31P magic-angle spinning NMR spectroscopy was used to verify the presence of covalent P–F bonds in 3. The different size effects, as well as the coordination environments of the Mg2+, Sr2+, and Ba2+ cations, on the structures as a whole have been discussed in detail. In addition, the calculated birefringence values were observed to differ from 0.011 to 0.033 for the four compounds.
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DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2026
·
IF 9.6
Linlin Wang,Yafei Guo,Wenhui Zhao,Pengfei Wang,Zonglin Liu,Ting-Feng Yi
A unique 3D hierarchical network consisting of 0D carbon dodecahedra and 1D carbon nanotubes is successfully constructed via in-situ growth. • Phosphorus doping serves as a versatile modulator to induce 1D morphology formation and optimize the electronic density of iron active centers. • The optimized N, P co-doped Fe-N-C catalyst exhibits an outstanding half-wave potential of 0.884 V in alkaline media. • The assembled zinc-air battery achieves a remarkable operational lifespan exceeding 1300 h with superior structural integrity. Developing highly efficient and durable non-precious metal electrocatalysts for oxygen reduction reaction (ORR) remains a critical challenge for the practical application of zinc-air batteries (ZABs). Herein, we successfully synthesized a robust N, P-codoped Fe-N-C catalyst featuring a unique 0D/1D intertwined architecture through a phosphorus-induced heteroatom-modulation strategy. By utilizing FePc-encapsulated ZIF-8 as a precursor, the in-situ growth of 1D carbon nanotubes from 0D carbon dodecahedrons was achieved, constructing a 3D hierarchical conductive network. Experimental and mechanistic analyses reveal that P-doping serves as the key morphology director. It not only induces the formation of structural-stable 1D nanotubes to enhance electron transfer but also modulates the electronic density of Fe centers to elevate electro-oxidation resistance. Consequently, the optimized catalyst exhibits a superior half-wave potential (E 1/2 ) of 0.884 V (vs. RHE) in alkaline media. Remarkably, the as-assembled ZAB achieves an exceptional stability of over 1300 h, demonstrating the superior structural integrity and durability of the 0D/1D network. This research offers a strategic design for engineering high-performance and stable Fe-N-C catalysts through synergistic 0D/1D architecture construction. Phosphorus-induced modulation facilitates the in-situ growth of 1D nanotubes from 0D dodecahedrons, constructing an integrated 0D/1D hierarchical Fe-N-C structure. This structural engineering optimizes the electronic environment of Fe sites for enhanced ORR kinetics (E 1/2 = 0.884 V) and endows practical zinc-air batteries with an outstanding stability exceeding 1300 h. Download: Download high-res image (283KB) Download: Download full-size image
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DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Jiangtao Meng,Tao Wang,Lei Ren,Jing Wang,Yuanyuan Zhang,Jingkuan Li,Fei Wang
Stage-matched framework reveals fuel-N pathway shifts. • Microwave shifts NH 3 and HCN release to lower temperature regions. • Microwave enriches amines and nitrile precursors in tar at lower temperatures. • Microwave promotes early char deoxygenation and condensation. • Polar O/N activation couples char-N reconstruction with tar-N evolution. Microwave-assisted pyrolysis shows promise for the clean conversion of N-rich biomass, yet its mechanism for regulating nitrogen migration remains unclear. Deashed sewage sludge and protein-derived amino acid models were employed to contrast microwave and conventional pyrolysis. This comparison utilized a reaction-stage-referenced framework based on the characteristic release regions of N-containing gases. Microwave heating did not change the basic nitrogen release pattern, with NH 3 as the dominant product and HCN as the secondary product, but substantially altered the temperature-dependent progression of the fuel-N conversion pathway. Under the present microwave experimental configuration, substantial fuel-N conversion was observed within the measured 190–300 °C range, occurring at lower measured temperatures than under conventional pyrolysis and accompanied by marked changes in O/N-containing structures. Amine intermediates were enriched in tar, and the tar-N fraction increased from about 44% to 87%, driving NH 3 release to lower temperatures. At 300–500 °C, these intermediates further underwent dehydrogenation, cyclization, and nitrilation under microwave effects, forming nitriles and low-carbon mono‑nitrogen compounds and enhancing HCN release around 300 °C. As a result, the characteristic NH 3 and HCN release regions were recorded at lower measured temperatures in the microwave system than in the conventional system. Meanwhile, microwave heating promoted early char deoxygenation and condensation, as reflected by protein-N conversion to pyrrolic-N, pyridinic-N, and nitrile-N, removal of C O and O-C=O groups, reduced interlayer spacing, and enhanced microcrystalline stacking. Tar evolved from heterocyclic and long-chain N-containing compounds toward light aromatics, oxygenated species, and low-carbon nitriles. A three-phase network is proposed wherein tar acts as an intermediate pool connecting char-N reconstruction with NH 3 /HCN release. This study provides mechanistic insights into fuel-N migration during microwave and conventional pyrolysis of N-rich sewage sludge. Download: Download high-res image (180KB) Download: Download full-size image
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