Journal of Innovative Optical Health Sciences
·
2024
·
IF 2.3
Zhenghao Liu,Ziyue Ju,Hanyu Liu,Zhan Wang,Ruichan Lv
Rare earth luminescent materials have attracted extensive attention in the biomedical field as noncontact temperature monitoring devices with microscopic resolution due to their properties in the visible and near-infrared regions. At the application level, it is required to have a certain temperature monitoring capability in the near-infrared region II window to enhance the tissue penetration depth. Here, two kinds of YOFs: Er 3 + , Yb 3 + were prepared by co-precipitation and hydrothermal method, and the luminescence was enhanced by ion doping. An Er 3 + -based ratiometric nanothermometer of 4 F 9 ∕ 2 → 4 I 1 5 ∕ 2 (672 nm, upconversion luminescence) to 4 I 1 3 ∕ 2 → 4 I 1 5 ∕ 2 (1580 nm/1566 nm, NIR II downshifting luminescence) were designed with the Stark energy level. When doped with 2% Zn 2 + , the relative temperature sensitivity of YOF prepared by co-precipitation method was improved from 0.30% ∘ C − 1 (30 ∘ C) to 0.59% ∘ C − 1 (30 ∘ C), expanding its use as a temperature monitoring device possibility. The temperature sensitivity of YOF prepared by hydrothermal method was 1.01% ∘ C − 1 (30 ∘ C). Finally, the NIR II luminescence of the prepared nanothermometer was used as a control for temperature monitoring of heating sites in mice. The results showed that it can distinguish heating site from control site and no significant cytotoxicity or damage to the tissues was revealed, indicating its broad prospects in the biomedical field and other temperature monitoring scenarios in the future.
研究领域:
生物医学
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材料科学
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DOI
高影响因子
CERAMICS INTERNATIONAL
·
2022
·
IF 5.532
Yaqi Zhu,Jian Yang,Mingwei Wang,Yangqi Meng,Rongyun Jiang,Hancheng Zhu,Duanting Yan,Chunguang Liu,Changshan Xu,Yuxue Liu
In this study, spinel-phase Zn 2 Ga 3- x Fe 3+ x Ge 0.75 O 8 ( x = 0, 0.002, 0.004, 0.02, 0.04, 0.08, 0.2) and Zn 2 Ga 2.98- x Fe 3+ x Cr 0.02 Ge 0.75 O 8 ( x = 0, 0.0004, 0.001, 0.002 0.003, 0.004) nanoparticles were prepared by one-step hydrothermal method in combination with vacuum annealing. For ZGGO: Fe 3+ nanoparticles , the near infrared (NIR) emissions (∼725 nm) originate from the 4 T 1 ( 4 G)→ 6 A 1 ( 6 S) transition of Fe 3+ occupying octahedral and tetrahedral sites of Ga 3+ . Furthermore, their afterglow time is more than 15 min and Fe 3+ doping will influence the generation of antisite defects pair ( Ga Zn 0 − Zn Ga ′ ). For Cr 3+ and Fe 3+ co-doped ZGGO nanoparticles with average size of ∼46 nm, the NIR persistent luminescence around ∼700 nm, originating from the 2 E→ 4 A 2 and 4 T 2 → 4 A 2 transitions of Cr 3+ , can be observed and the afterglow time exceeds 850 min. With the increase of Fe 3+ concentration, the afterglow intensity decreases due to the decreased number of ( Ga Zn 0 − Zn Ga ′ ) defects and deeper traps. In particular, autofluorescence-free imaging and MR imaging were successfully realized by using ZGGO: Cr 3+ , Fe 3+ 0.002 nanoparticles dispersed in the simulated biological fluid environments (H 2 O, SLS and HSA). Their clear afterglow images can be acquired within 3 min after the stoppage of the UV irradiation and their transversal relaxivity (r 2 ) is in the range of 227–140 mM −1 s −1 , which is close to the conventional Feridex T 2 agent (108 mM −1 s −1 ). Our results suggest that ZGGO: Cr 3+ , Fe 3+ nanoprobes have potential applications in the diagnosis and therapy of disease.
研究领域:
材料科学
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医学影像学
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生物医学工程
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DOI
高影响因子
Advanced Optical Materials
·
2024
·Vol. 12
·期 16
·2303144
·
IF 8
Mengdi Xu,Zhongyuan Li,Qiqi Li,Tinglin Mou,Xuesong Wang,Dong Yan,Ye Li,Xianju Zhou,Zhen Fang,Lixin Ning
Broadband near-infrared (NIR) emissions in the long wavelength region with simultaneous high efficiency and thermal stability are desirable for NIR phosphor-converted light-emitting diodes (NIR pc-LEDs) light sources. Herein, a novel broadband NIR-emitting phosphor is reported, Ba 5 La 3 MgAl 3 O 15 :Cr 3+ (BLMAO:Cr 3+ ), which exhibits a NIR emission band spanning 700–1300 nm with maximum peak wavelength ( λ max ) at 925 nm and full width at half maximum of 160 nm. The optimized phosphor achieves an internal quantum efficiency of 66%, and the integrated emission intensity at 423 K remains 61% of that at room temperature, which surpasses most Cr 3+ -activated phosphors emitting in the long-wavelength NIR region ( λ max > 900 nm). The NIR luminescence properties are elucidated on the basis of density functional calculations of the multiple Cr 3+ local structures as generated by the Ba/La occupation disorder in the host material. The applications of the NIR phosphor in pc-LED devices are demonstrated, showing potential in night-vision and nondestructive examination. The results indicate that BLMAO:Cr 3+ is a promising phosphor with highly efficient and thermally stable broadband NIR emission for NIR LED light sources.
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DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2019
·Vol. 29
·期 38
·1904416
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IF 15.621
Huai Yang,Longfei Pan,Xiaoting Wang,Hui-Xiong Deng,Mianzeng Zhong,Ziqi Zhou,Zheng Lou,Guozhen Shen,Zhongming Wei
Mixed-valence states can bring unexpected unique phenomena, especially novel anisotropic physics, due to structural asymmetry, which originate from the discrepant distribution of atoms with different valence. This study reports an unexploited mixed-valence-driven quasi-1D Sn II Sn IV S 3 crystal, which exhibits widely and distinctively anisotropic polarized-light absorption reaching ≈3.4 from the deep ultraviolet to near-infrared region (250–850 nm). The fabricated polarization-sensitive photodetectors based on highly air-stable Sn II Sn IV S 3 nanowires display strong linear dichroism among the UV–vis–NIR spectrum with responsivity exceeding ≈150 A W −1 . Furthermore, the devices are further constructed onto a flexible polyethylene terephthalate (PET) substrate and the photoresponse remains roughly unchanged after repeated bending. This work based on novel mixed-valence-driven quasi-1D ternary sulfide Sn II Sn IV S 3 excites interest in low-symmetry semiconductors for developing broadly spectral polarization-sensitive photodetectors with environmental stability and mechanical flexibility.
研究领域:
材料科学
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半导体物理
·
纳米光学
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光电子学
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凝聚态物理
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Hongjun Song,Weijie Zhang,Ya Zhang,Caixia Yin,Fangjun Huo
Intracellular viscosity plays an important role for maintaining the diffusion, transportation, signal transmission and cell metabolism between biomolecules. And abnormal intracellular viscosity would cause various concurrent diseases such as fatty liver, hyperlipidemia and so on. However, as far as we know, there are quite few tools could be used for imaing of intracellular viscosity, much less in-depth investigation of the viscosity-related dysfunctional and disease. Herein, we have designed and developed a series of NIR fluorescent probes , in which the chemical bond between fluorophore and molecular rotor was designed with single bonds, double bonds, and extended double bonds, respectively. According to the theoretical calculations and experiments results, BP-III with was selected as the most sensitive fluorescence sensor for imaging viscosity change in vitro and in vivo. As the viscosity increasesd, the TICT (twisted intramolecular charge transfer) of BP- III was inhibited, accompanied with a strong red fluorescence enhancement at 740 nm. In addition, BP- III showed excellent mitochondrial target ability and can be used to imaging viscosity changes in mitochondrial of living cells. More importantly, the probe has been used for imaging the abnormal viscosity of fatty liver at the organ level. We expect this work would provide meaningful tool for promoting fundamental research in biological viscous environment and mitochondrial viscosity related diseases.
研究领域:
生物成像
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分子探针
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线粒体生物学
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代谢性疾病
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荧光光谱学
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DOI
高影响因子
Journal of Materials Chemistry C
·
2019
·Vol. 7
·期 13
·3751-3755
·
IF 6.641
Jiao Ma,Hao Wu,Jianbei Qiu,Jing Wang,Qi Wang,Yong Yang,Dacheng Zhou,Jin Han
All-inorganic CsPbX3 (X = Cl, Br, and I) perovskite quantum dots have great potential in the field of white light emission owing to their excellent optical properties. However, to date the research on white light based on perovskite quantum dots has focused on downconversion luminescence, while the up-conversion luminescence properties of quantum dots have received less attention due to lacking the anti-Stokes luminescence properties of the material itself, resulting in limitations in upconversion white light emission to some extent. In this paper, upconversion lanthanide ion-doped fluoride nanoparticles and perovskite quantum dots are combined; the luminescence of the quantum dots is excited successfully by the upconversion luminescence of the nanoparticles and then composite samples with white emission are obtained with regulators of concentration.
研究领域:
光电子学
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纳米材料
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光子学
·
发光材料
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DOI
高影响因子
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
·
2024
·Vol. 51
·期 10
·2941-2952
·
IF 8.6
Wang Yajun,Zhou Ding,Ma Huilong,Liu Dahai,Liang Yongye,Zhu Shoujun
Purpose The accuracy of surgery for patients with solid tumors can be greatly improved through fluorescence-guided surgery (FGS). However, existing FGS technologies have limitations due to their low penetration depth and sensitivity/selectivity, which are particularly prevalent in the relatively short imaging window (< 900 nm). A solution to these issues is near-infrared-II (NIR-II) FGS, which benefits from low autofluorescence and scattering under the long imaging window (> 900 nm). However, the inherent self-assembly of organic dyes has led to high accumulation in main organs, resulting in significant background signals and potential long-term toxicity. Methods We rationalize the donor structure of donor–acceptor-donor-based dyes to control the self-assembly process to form an ultra-small dye nanocluster, thus facilitating renal excretion and minimizing background signals. Results Our dye nanocluster can not only show clear vessel imaging, tumor and tumor sentinel lymph nodes definition, but also achieve high-performance NIR-II imaging-guided surgery of tumor-positive sentinel lymph nodes. Conclusion In summary, our study demonstrates that the dye nanocluster-based NIR-II FGS has substantially improved outcomes for radical lymphadenectomy.
研究领域:
生物医学成像
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肿瘤外科手术
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纳米医学
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分子探针
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光学成像
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DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2019
·Vol. 43
·期 25
·10025-10029
·
IF 3.069
Xinrong Shi,Fangjun Huo,Jianbin Chao,Yongbin Zhang,Caixia Yin
The role of hydrazine in production is not to be underestimated due to its strong reducibility. However, every coin has two sides. Hydrazine represents a great hazard to the environment, which cannot be ignored. Aiming to prevent harm to people or the environment, a new near-infrared fluorescent probe is presented. This probe is specifically designed to sense hydrazine vapor accumulated in an enclosed space and detect excessive hydrazine in water samples. It shows good selectivity and a turn-on effect, as well as a remarkable color change that can be distinguished by the naked eye. This effect has been utilized for quantitative detection in real water samples. Moreover, the color change of the probe adsorbed on filter paper can be observed by the naked eye to monitor the presence of hydrazine in the air in real time; this property of the probe is expected to be used for hydrazine detection in industrial environments.
研究领域:
分析化学
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环境科学
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生物传感
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分子诊断
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工业安全监测
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DOI
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Yue Wang,Aofeng Yang,Lihao Xiong,Jiayi Song,Sihan Chen,Huang Zhou,Le Li,Deshuai Zhen
Uranium, a radioactive element, exists in aqueous environments primarily as uranyl ions (UO22+), posing significant risks to human health and the environment. Detecting UO22+ in such environments remains challenging. Here, an upconversion fluorescent sensor (UCDM) for the detection of UO22+ in an aqueous environment was constructed based on the fluorescence resonance energy transfer (FRET) principle. This sensor utilizes upconversion nanoparticles loaded with DNAzyme (UCDA) as energy donors and molybdenum disulfide (MoS2) as energy acceptors. MoS2 exhibits a high affinity for single-stranded DNA (ssDNA), enabling the sensor to function effectively. In the presence of UO22+, DNAzyme catalyzes substrate cleavage at the rA site, releasing ssDNA that binds to MoS2. This interaction leads to a decrease in UCDA upconversion luminescence. The unique upconversion luminescence property of an upconversion nanoparticle minimizes background autofluorescence, enhancing sensitivity. The sensor achieves a low detection limit of 5.81 nM and demonstrates robust recoveries (98.7%–102.7%) in complex aqueous matrices such as Xiangjiang water, uranium mine wastewater, human serum, and urine samples, underscoring its practical applicability.
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产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2018
·
IF 3.927
Hui Xu,Yunfang Huang,Dan Luo,Xiaomin Yang,Shao Jin,Qiyao Guo,Yuezhu Zhao,Yu Fang,Yuelin Wei,Jihuai Wu
In this work, multiple heterojunction Ag/Bi/BiOCl 0.8 Br 0.2 photocatalysts with novel porous micro-flower structure were fabricated via a facile one-step solvothermal route and characterized systematically. The TEM and HRTEM images clearly showed the heterogeneous nanostructures at the interface between Ag/Bi and BiOCl 0.8 Br 0.2 . The as-prepared Ag/Bi/BiOCl 0.8 Br 0.2 composites displayed a strong optical absorption in the region of 250–1500 nm, especially in the unexploited near infrared region which accounts for most of the sunlight. The multiple heterojunction photocatalyst exhibited an outstanding photocatalytic activity for the degradation of Rhodamine B under the UV, visible and NIR light irradiation, respectively. The highly enhanced photocatalytic activity was attributed to the synergistic effects, including the reduced band gap, the surface plasmon resonance effect, efficient charge separation of photo-generated electron-holes. On the basis of the radical species trapping experiments, the holes and superoxide radicals were confirmed to be the mainly active species involved in the degradation of Rhodamine B under the NIR light irradiation. This study provides a novel strategy for designing highly performance plasmonic photocatalysts under the whole solar light irradiation.
研究领域:
材料科学
·
环境科学
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DOI
高影响因子
ACS Applied Materials & Interfaces
·
2020
·
IF 8.758
Chunyao Wang,Nuoya Zhao,Weizhong Yuan
Injectable and self-healing hydrogels with thermoresponsiveness as smart hydrogels displayed injectability, automatic healing, and phase and volume changes as well. Here, the thermoresponsive self-healing hydrogel was prepared via the formation of dynamic covalent enamine bonds between the amino groups in polyetherimide (PEI) and the acetoacetate groups in the four-armed star-shaped poly(2-(dimethylamino)ethyl methacrylate-co-2-hydroxyethyl methacrylate) modified with tert-butyl acetoacetate (t-BAA), SP(DMAEMA-co-HEMA-AA). After adding polydopamine nanoparticles (PDA NPs), the SP(DMAEMA-co-HEMA-AA)/PEI/PDA-NP nanocomposite hydrogel presented phase change and volume shrinkage under near-infrared (NIR) irradiation. The thermoresponsive nanocomposite hydrogel loaded with the anticancer drug doxorubicin (DOX) could be injected into the 4T1 tumor by intratumoral injection. After NIR laser irradiation, the temperature of the hydrogel increased because of the photothermal effect of PDA NPs inducing local hyperthermia. Because the hydrophilicity–hydrophobicity transition of the hydrogel occurred, DOX molecules were squeezed out from the hydrogel at temperatures higher than its lower critical solution temperature (LCST) and the tumor cells suffered from internal stress from the shrunk hydrogel. The injectable nanocomposite hydrogel not only demonstrated the synergism of highly efficient thermochemotherapy but also showed the function of improving drug utilization and precise treatment to reduce the side effects of drugs.
研究领域:
材料科学
·
生物医学工程
·
肿瘤学
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DOI
PubMed
高影响因子
CERAMICS INTERNATIONAL
·
2024
·
IF 5.1
Yixin Sun,Yining Wang,Minliang Deng,Xiaole Xing,Yiying Zhu,Mengmeng Shang
The swift progress in portable spectrometer technology has fostered a widespread need for compact light sources. Concurrently, near-infrared phosphor-converted light-emitting diodes (NIR pc-LEDs), characterized by their low cost and compact structure, emerge as an optimal choice. Inspired by phase optimization through fluxes, we successfully synthesized pure phase Lu 3 Mg 2 GaSi 2 O 12 (LMGS):Cr 3+ , 3 wt%MgF 2 luminescent materials by incorporating various fluxes including LiF, NaF, MgF 2 , CaF 2 , SrF 2 and BaF 2 . These materials emit broadband NIR light ranging from 620 nm to 1150 nm, with full width at half-maximums (FWHMs) exceeding 125 nm. By employing a dual-fluxes strategy to further enhance the luminescence intensity of Cr 3+ , the LMGS:3%Cr 3+ , 1 wt%NaF, 2 wt%MgF 2 sample exhibits a 2.45 times increase in emission intensity compared to the LMGS:3%Cr 3+ , 3 wt%MgF 2 sample. Concurrently, the quantum efficiency rises from 24 % to 46 %. Moreover, the integrated emission intensity of LMGS:3%Cr 3+ , 1 wt%NaF, 2 wt%MgF 2 retains at 75 %@425 K of its value at RT. Upon coupled with a 430 nm LED chip, the luminescent material exhibits an NIR output power of 43.8 mW@300 mA, indicating promising applications in rapid night identification, night vision and non-destructive testing.
研究领域:
材料科学
·
光学材料
·
固态照明
·
光子学
·
无机化学
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DOI
高影响因子
危险品化学品经营许可证（带存储）