NEW JOURNAL OF CHEMISTRY
·
2020
·Vol. 45
·期 6
·3102-3111
·
IF 3.288
Tehseen Nawaz,Muhammad Ahmad,Jieying Yu,Shiqi Wang,Tianxin Wei
A novel tetracycline (TC) imprinted polymer was prepared in visible light via synergy of dual functional group monomers methacrylic acid (MAA) and itaconic acid (IA) for the selective detection of TC in urine and milk samples. Surface plasmon resonance (SPR) and the reversible addition fragmentation chain transfer (RAFT) mechanism were employed in combination with 4-cyano-4-[(dodecylsulfanylthiocarbonyl)sulfanyl]pentanoic acid (CDTPA) in the presence of ethylene glycol dimethacrylate (EGDMA) as the cross-linker. In addition, the ratio of template, IA, MAA and EGDMA was optimized (0.8 : 0.3 : 5 : 9) by real time monitoring via SPR. The surface of the TC imprinted sensor chip was characterized by contact angle measurements, Fourier Transform Infrared Spectroscopy (FTIR) and Scanning Electron Microscopy (SEM). The (IA–MAA@SPR)MIP sensor chip displayed a high adsorption capacity and selectivity in comparison to other analogues and non-imprinted polymer (NIP) based sensor chips. Through 7 adsorption–desorption cycles, the (IA–MAA@SPR)MIP sensor chip exhibited a good recoverability. These features suggested that the IA–MAA based sensor chip was an ideal candidate for the detection of TC. Consequently, within the concentration range of 1 × 10−13–1 × 10−7 mol L−1, the reflectivity changes versus the negative logarithm of concentrations presented excellent linearity; R2 = 0.99. Based on a linear equation, the IA–MAA@SPR MIP sensor chip showed lower values for the limit of detection (LOD) and limit of quantification (LOQ) i.e. 1.38 × 10−14 mol L−1 and 4.5 × 10−14 mol L−1, respectively. Furthermore, the influence of the matrix on the sensor chip was successfully analyzed in real samples with satisfactory outcomes. Hence, IA–MAA based MIPs in combination with the SPR sensor chip demonstrated potential application prospects for rapid and effective sensing even in the complicated matrices.
研究领域:
分析化学
·
材料科学
·
传感器
·
环境科学
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DOI
高影响因子
Polymer Chemistry
·
2023
·Vol. 14
·期 47
·5178-5190
·
IF 4.6
Ranran Gao,Xiaoning Guo,Li Wang,Wantai Yang
Stimuli-responsive aggregation-induced emission (AIE) active polymers with structural diversity and tunability in fluorescence responsive behavior are in high demand in practical applications. Recently, tetraphenylethylene (TPE)-appended maleic anhydride terpolymers were proposed as a multi-stimuli-responsive fluorescence platform by our group. Here, we report TPE-containing styrene–maleic acid copolymers with diverse chain topologies and locations of the TPE moiety by reversible activation-fragmentation transfer polymerization (RAFT) with meticulously designed chain transfer agents and a TPE-containing monomer. The fluorescence responsiveness of the copolymers to the pH value, Ca2+, and bovine serum albumin (BSA) was systematically investigated, which showed an influence substantially on both the “stimuli acceptor” and “signaling” sides of the macromolecular structure. The discovery made in our work accentuates the importance of macromolecular engineering in developing fluorescent probes with highly differentiated performance and provides great flexibility in meeting the wide range of requirements of various applications.
研究领域:
高分子化学
·
材料科学
·
分析化学
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DOI
高影响因子
MACROMOLECULAR CHEMISTRY AND PHYSICS
·
2023
·Vol. 225
·期 5
·2300361
·
IF 2.5
Dan Liu,Hui Liang,Jiang Lu
A novel monomer, N -(2-((3-morpholine-3-isopropyl)thio)ethyl)methacrylamide (MTMA), is synthesized and polymerized by reversible addition-fragmentation chain transfer (RAFT) polymerization to give a thermoresponsive polymer poly[ N -(2-((3-morpholino-3-oxopropyl)thio)ethyl)methacrylamide] (PMTMA). PMTMA exhibits reversible thermoresponsive phase transitions of the lower critical solution temperature (LCST) type in water and the upper critical solution temperature (UCST) type in ethanol and methanol. The degree of polymerization and concentration of PMTMA, and solvent type have a significant influence on the transition temperature. PMTMA shows complicated thermoresponse in water–alcohol mixtures. In water–ethanol mixtures, the phase diagram of PMTMA can be divided into three regions according to ethanol volume percentages, φ : 0 ≤ φ < 15% for an LCST region; 15% ≤ φ < 91.5% for a complete dissolution region; 91.5% ≤ φ ≤ 100% for a UCST region. At high water content, the LCST increases with increasing ethanol content; and at high ethanol content, the UCST decreases with increasing water content. In water–methanol mixtures, PMTMA shows more complex thermoresponse. In the range of 0–50 °C, the phase diagram can be divided into five regions, depending on the methanol volume percentages φ : 0 ≤ φ < 15% for LCST region; 15% ≤ φ < 25% for immiscible region; 25% ≤ φ < 85% for UCST region; 85% ≤ φ < 95% for fully dissolved region; 95% ≤ φ ≤ 100% for another UCST region.
研究领域:
高分子化学
·
材料科学
·
物理化学
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DOI
高影响因子
MATERIALS CHEMISTRY AND PHYSICS
·
2019
·
IF 2.781
Haicun Yang,Zinan Cai,Haotian Liu,Zheng Cao,Yanping Xia,Wenzhong Ma,Fanghong Gong,Guoliang Tao,Chunlin Liu
In this work, we proposed the tuning of the interface between attapulgite (ATP) and polycarbonate (PC) by the surface tailoring of ATP via a combination of RAFT polymerization and alkynyl-thiol click reaction. The side alkynyl-functionalized random copolymer poly(MMA- co -PgMA) was synthesized as the immobilization block via redox-initiated room-temperature RAFT copolymerization of MMA and propargyl methacrylate (PgMA). Then, the dispersion block was synthesized by room-temperature RAFT polymerization of MMA using poly(MMA- co -PgMA) as the macro chain transfer agent to afford poly((MMA- co -PgMA)- b -MMA). FTIR, 1 H NMR, gel permeation chromatograph (GPC), and kinetic results indicated the successful synthesis of copolymers with well-defined structures. Copolymers with different length of PMMA segment were tethered onto the surface of thiol-functionalized ATP via alkynyl-thiol click reaction to mediate the interfacial interaction between ATP and PC, the successful covalent grafting of copolymers was confirmed by FTIR, TGA , XPS and XRD , and the effects of dispersion blockchain length on nanocomposites were investigated. The functionalized ATP demonstrated an improved dispersity in nanocomposites and enhanced mechanical properties with increasing dispersion blockchain length. The PC nanocomposites with functionalized ATP showed lower T g and complex viscosity as compared to that of pure PC and nanocomposites with bare ATP, which enhanced the processability of nanocomposites.
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产品关联
DOI
高影响因子
MACROMOLECULES
·
2023
·
IF 5.5
Jie Cai,Xiyu Wang,Yuanyuan Liu,Caihui Luo,Xinhua Lu,Yuanli Cai
We herein report a site-specific polymerization-induced electrostatic self-assembly (PIESA) that enables the precision synthesis of highly charged salt-tolerant nanoreactors. Site-specific PIESA is achieved using an anionic aromatic–aliphatic sulfonate block copolymer in photoinitiated reversible addition-fragmentation chain transfter (photo-RAFT) polymerization of a cationic monomer in water at 25 °C. Preferential complexation of cationic growing chains to the aromatic sulfonate block results in not only site-specific molecular recognition but also unique salt-tolerant PIC nanoparticles. Neutral block incorporation leads to ultrafast reaction of very dilute monomer (2.0% w/w) and exclusive formation of more salt-tolerant smaller spheres or 4 nm fibril-structured 10 nm ultrathin lamellae. The ultrathin lamellae can induce a sequence-controllable ultrafast copolymerization of oppositely-charged dilute monomers with perfect shape/size preservation up to 100% conversions, and thus can be viewed as a nanoreactor. This work opened up an avenue for the precision synthesis of highly charged salt-tolerant PIC functional nanoparticles, providing a versatile platform for easy access to structural and functional complexity from simple mixtures.
研究领域:
聚合物化学
·
材料科学
·
纳米技术
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DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 111
·91140-91146
·
IF 3.84
Shuang-Shuang Zhang,Shao-Kui Cao,Su Wang,Qiao-Ling Zhao,Jian-Zhuang Chen,Kun Cui,Zhi Ma
Well-defined α-fluorinated alkyl ester, ω-carboxyl telechelic polystyrenes (PS) were synthesized via combining aminolysis of RAFT-polystyrene and thiol–ene “click” reaction simultaneously. The perfluoroalkyl end groups were –CF3, –(CF2)2–CF3 and –(CF2)7–CF3, respectively. Highly ordered porous films of such telechelic PS with an average pore size about 1.00 μm were fabricated via a static breath-figure process. With the content of fluorine on the surface of porous films increasing from 1.04 wt%, to 1.64 wt% and 2.97 wt%, respectively, the water contact angle (WCA) of such porous films increased from 112° to 116° and 121° ± 0.4°, respectively, indicating their hydrophobicity. Interestingly, microspheres with average diameters of ca. 0.30–0.65 μm can be fabricated via a static BF process using methanol instead of water as the vapor atmosphere in the glass vessel.
研究领域:
高分子化学
·
材料科学
·
纳米技术
·
表面工程
·
软物质物理
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DOI
高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2023
·
IF 4.7
Yutuo Wang,Yintao Li,Zhengquan Zhang,Mengqing Xiao,Changwen Chen,Yuanlin Zhou,Shanqiang Wang
Nuclear facilities generate lots of contaminated stainless steel metallic material during maintenance and decommissioning. As a new radioactive decontamination method, the self-embrittle decontamination method has the advantage of less secondary contaminants and being able to operate machinery remotely. Adding a certain amount of corrosive components to the self-embrittle compound detergent can achieve the dual functions of self-embrittlement and corrosive decontamination. It was used to optimized the response surface methodology (RSM) and train and evaluate four different machine learning models by the recorded data set. The purpose of the analysis was to quantify the accuracy of the corrosion decontamination effect of RSM model and four types of machine learning model. The results exhibits that the long short-term memory neural network (LSTM) model performs well. The prepared detergent can achieve the average corrosion depth of 5.9454 μm on stainless steel, which can satisfy the corrosion decontamination of radioactively contaminated stainless steel surfaces.
研究领域:
材料科学
·
核工程
·
化学工程
·
人工智能
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DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Mengqing Yang,Jianhai Yang,Rong Liu,Liping Chen,Danyang Chen,Yu He,Yang Li,Huaying Wang,Keqi Tang,Zhengyan Hu,Zhenbin Zhang
Capillary coating plays a crucial role in the separation efficiency and reproducibility of capillary zone electrophoresis (CZE). In this study, a linear poly(N-(2-hydroxypropyl)methacrylamide) (LP(HPMA))-coated capillary was prepared by using the surface-confined aqueous reversible addition–fragmentation chain transfer polymerization method. The LP(HPMA)-coated capillary exhibits better biocompatibility and stability compared with the linear poly(acrylamide) (LPA)-coated capillary. Through systematic evaluation, the optimal conditions for fabricating LP(HPMA)-coated capillaries were determined as follows: 1 M HPMA, 2.7 × 10–3 M 4,4′-azobis(4-cyanovaleric acid), and a reaction time of 4 h. LP(HPMA)-coated capillaries prepared under these conditions exhibited the lowest electro-osmotic flow values of 3.7 × 10–6 and demonstrated exceptional performance when applied to the analysis of a HeLa cell digest. Following a 20-day treatment with 2 M NH4OAc (pH 7), the number of peptides identified using the LP(HPMA)-coated capillary decreased by 18.1% compared to the untreated LP(HPMA)-coated capillary; in contrast, the peptide numbers for the LPA-coated capillary decreased by 26.7% relative to its untreated counterpart. These results indicate that the LP(HPMA)-coated capillary exhibits superior pH stability compared to the LPA-coated capillary within the physiological pH range. The LP(HPMA)-coated capillary was employed in the clinical proteomics analysis of non-small cell lung cancer tissues and their corresponding paracancerous tissues via CZE-ESI-MS/MS. The differentially expressed proteins in each sample pair demonstrated minimal overlap, highlighting the heterogeneity of tumor tissues among different patients. Principal component analysis of the data could segregate the samples into a tumor tissue cluster and a paracancerous tissue cluster. Moreover, within each cluster, samples from different patients further separated into subclusters. This discovery validates that CZE-MS can not only distinguish between lung cancer tumor tissue and paracancerous tissue but also detect the heterogeneity among diverse patients, even with as little as 100 ng of sample. The obtained results were subsequently compared with those from nanoRPLC-MS using 1 μg of sample. Notably, the enrichment results within the three gene ontology categories for both methods showed a high level of consistency, corroborating the effectiveness of the CZE-MS method using an LP(HPMA)-coated capillary in identifying differentially expressed proteins from mass-limited clinical samples.
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产品关联
DOI
PubMed
高影响因子
European Physical Journal Plus
·
2024
·Vol. 139
·期 1
·1-13
·
IF 2.8
Wang Runda,Jiang Zhongying,Yang Fangyuan,Lei Yiteng,Sheng Jie
This study presents a novel category of tough PS-p(AAm-co-MBAA) double network (DN) hydrogels, synthesized through fully chemically cross-linked methods by introducing polyacrylamide network into hydrophobic polystyrene networks. Herein, we obtain the carboxyl-modified polystyrene (CPS) synthesized by polystyrene (PS) using reversible addition–fragmentation chain transfer (RAFT) polymerization, CPS and 4-arm amine poly(ethylene glycol) (4-arm-PEG-NH 2 ) serve as the first chemical cross-linking, providing a brittle and stiff network that allows energy dissipation. Concurrently, the second chemical cross-linking points, created by acrylamide (AAm) and N,N’-methylenebis(acrylamide) (MBAA), impart a ductile and soft network to enhance stretchability. The optimal tough PS-p(AAm-co-MBAA) DN hydrogel displays remarkable properties, including super stretchability (≈5.9 times), tensile strength (≈0.43 MPa), high toughness (≈1.66 MJ m −3 ), good recoverability property (≈94.6% stiffness recovery and ≈88% toughness recovery without any waiting time), and fatigue resistance. This study introduces a novel approach to design and manufacture tough hydrogels with remarkable overall characteristics by employing the collaborative process of RAFT polymerization. Graphical
研究领域:
材料科学
·
高分子化学
·
软物质物理
·
机械工程
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DOI
高影响因子
EUROPEAN POLYMER JOURNAL
·
2022
·
IF 5.546
Jinying Wang,Jiannan Cheng,Kai Tu,Yuxue Wang,Qing Yu,Lifen Zhang,Zhenping Cheng
In this work, based on the semifluorinated macro-RAFT (reversible addition-fragmentation chain transfer) agent and polymerization-induced self-assembly (PISA) strategy, we established a mild and facile method to prepare reversed micelles up to 40 wt% of solid content with main-chain-type semifluorinated alternating copolymer as shell and hydrophilic polymer as core for the first time. The fluorinated macro-RAFT agent was synthesized by combination of step transfer-addition & radical-termination (START) polymerization and post-modification method. The reversed micelles were generated by the PISA of N,N -dimethacrylamide (DMA) in the presence of the fluorinated macro-RAFT agent in the non-polar solvent toluene at 70 °C, and fluorinated reversed micelles can be fixed in the presence of crosslinker ethyleneglycol dimethacrylate (EGDMA). This strategy will facilitate to open a new way in designing novel functional synthetic fluorinated nanomaterials.
研究领域:
高分子科学
·
材料化学
·
纳米技术
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DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Jinsheng Zhou,Yanming Lin,Ling Wang,Li Zhou,Bin Yu,Xianghui Zou,Zhongkuan Luo,Huiyuan Hu
A novel near-infrared (NIR) light induced photoinduced electron transfer-reversible addition - fragmentation chain-transfer (PET-RAFT) polymerization was developed and carboxybetaine methacrylate (CBMA) polymer brush was constructed on the PVA hydrogel via this one-spot method to enhance the antifouling properties. PVA-g-pCBMA hydrogel displayed higher hydrophilicity , while the thermal properties decreased due to the lower decomposition properties of pCBMA and the partly destruction of crystal structure inside the PVA hydrogel. The antifouling properties of PVA-g-pCBMA hydrogel was improved significantly because the surface hydration and steric repulsion effect of pCBMA polymer brush. Importantly, PVA-g-pCBMA hydrogel PVA-g-pCBMA hydrogel could be considered as no cytotoxic effect or reduction of proliferation to primary human eyelid fibroblast cells following the guidelines stated by ISO 10993-5:2009 (direct contact test). Considering the excellent penetration ability of NIR, AlPc catalyzed PET-RAFT polymerization provided a new modification approach for various biological or medical materials on industrial scale.
研究领域:
材料科学
·
高分子化学
·
生物医学工程
·
表面科学
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DOI
高影响因子
Gels
·
2025
·Vol. 11
·期 8
·586
·
IF 5.3
Lihan Rong,Tianqi Guan,Xinyi Fan,Wenjie Zhi,Rui Zhou,Feng Li,Yuyan Liu
Fe3+-incorporated hydrogels are particularly valuable for wearable devices due to their tunable mechanical properties and ionic conductivity. However, conventional immersion-based fabrication fundamentally limits hydrogel performance because of heterogeneous ion distribution, ionic leaching, and scalability limitations. To overcome these challenges, we report a novel one-pot strategy where controlled amounts of Fe3+are directly added to polyacrylamide-sodium acrylate (PAM-SA) precursor solutions, ensuring homogeneous ion distribution. Combining this with Photoinduced Electron/Energy Transfer Reversible Addition–Fragmentation Chain Transfer (PET-RAFT) polymerization enables efficient hydrogel fabrication under open-vessel conditions, improving its scalability. Fe3+concentration achieves unprecedented modulation of mechanical properties: Young’s modulus (10 to 150 kPa), toughness (0.26 to 2.3 MJ/m3), and strain at break (800% to 2500%). The hydrogels also exhibit excellent compressibility (90% strain recovery), energy dissipation (>90% dissipation efficiency at optimal Fe3+levels), and universal adhesion to diverse surfaces (plastic, metal, PTFE, and cardboard). Finally, these Fe3+-incorporated hydrogels demonstrated high effectiveness as strain sensors for monitoring finger/elbow movements, with gauge factors dependent on composition. This work provides a scalable, oxygen-tolerant route to tunable hydrogels for advanced wearable devices.
研究领域:
材料科学
·
高分子化学
·
可穿戴电子器件
·
柔性机器人
·
传感器
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）