BIORESOURCE TECHNOLOGY
·
2026
·
IF 8.2
Zihang Wang,Yao Li,Yujing Wu,Jinliang Yan,Yuchun Zhang,Zhiyu Li,Peng Fu
Tungsten–carbon catalysts were designed for pathway-controlled cellulose hydrogenolysis. • Complete cellulose conversion with tunable selectivity to ethanol or diols was achieved. • WO x -derived Lewis acidity promoted selective C–C bond cleavage of glucose. • Metal–oxide interfacial sites enabled deep hydrogenolysis toward ethanol formation. • SO 3 H-modified catalysts regulated acid–metal cooperation toward C3 diol production. Cellulose, as the most abundant renewable carbon resource, offers great potential for the sustainable production of low-carbon alcohols. However, its catalytic hydrogenolysis remains challenging due to the difficulty in controlling product distribution and reaction pathways. Herein, two tungsten–carbon–based catalytic systems were rationally designed to direct cellulose hydrogenolysis toward ethanol or 1,2-propylene glycol through site-dependent catalysis. A multifunctional Mo-Pt-WO x /WC catalyst was constructed for ethanol production, while a sulfonated Mo/WC-SO 3 H catalyst was developed for selective formation of 1,2-propylene glycol. Under optimized conditions (245 ℃, 2 h, 5 MPa H 2 ), complete cellulose conversion was achieved over Mo-Pt-WO x /WC, delivering a total low-carbon alcohol yield of 68.1C% with an ethanol yield of 57.8C%. In contrast, Mo/WC-SO 3 H enabled complete cellulose conversion with a high 1,2-propylene glycol yield of 62.9C%. Experimental characterization suggests that SO 3 H-derived acidity may promote cellulose hydrolysis, while Mo-containing surface species may facilitate glucose isomerization and retro -aldol C–C bond cleavage. Density functional theory (DFT) calculations further reveal that WO x -derived acid sites favor selective C–C bond scission of glucose, whereas deep hydrogenolysis of ethylene glycol to ethanol is kinetically favored at Pt-MoO x interfacial sites. This work provides a practical strategy for steering cellulose hydrogenolysis toward different low-carbon alcohols through rational active-site design, and offers guiding principles for the rational development of multifunctional catalysts for biomass valorization. Download: Download high-res image (164KB) Download: Download full-size image
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ACS Applied Bio Materials
·
2026
·
IF 5.6
Fakang Zheng,Yinghua Mei,Meng Liu,Haidong Gong,Jianzhe Wang,Yingjian Wang,Jian Liu,Zhaozhu Zheng
Paclitaxel (PTX), as a broad spectrum and highly efficient antitumor drug, occupies an irreplaceable position in clinical cancer therapy. However, despite its definite therapeutic efficacy, its clinical application is largely limited by its extremely poor water solubility. Here, we report a facile method for encapsulating PTX into silk fibroin nanoparticles (PTX-SFNPs) using low molecular weight polyethylene glycol (L-PEG) as a solubilizer and high molecular weight polyethylene glycol (H-PEG) as an emulsifier and dehydrating agent, without adding any toxic organic solvents, surfactants, or other toxic agents. The efficiency at the volume of the reactor and processing time was 23.63 g/L, significantly higher than the desolvation method in ethanol and acetone. The PTX-SFNPs with a diameter of 100−300 nm exhibited promising drug loading (5.99 ± 0.28%) and encapsulation efficiency (30.91 ± 2.64%), excellent biocompatibility, and sustained drug release. In vivo studies using a mouse model with glioblastoma showed significant tumor inhibition without the systemic toxicity typical of traditional PTX formulations. Histological analysis confirmed the effective tumor penetration and biocompatibility of the nanoparticles. These findings suggest that PTX-SFNPs provide a promising approach for targeted glioblastoma therapy with the potential for future clinical applications.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Xupeng Fu,Wei Tian,Yuting Wang,Xionghui Wei,Zhaojun Wu,Jianbin Zhang
The influence of water content on the physicochemical properties of the H 2 O + (polyethylene glycol 300 (PEG300) + hydroxyethyl ethylenediamine (AEEA)) mixed system was investigated in detail. Density ( ρ ) and viscosity ( η ) were systematically measured over the temperature range of 298.15 K to 318.15 K under atmospheric pressure, and electrical conductivity was determined at 298.15 K. Based on the experimental data, excess molar volume ( V m E ), excess Gibbs free energy of activation for viscous flow ( ΔG ⁎E ), and viscosity deviation ( Δη ) were calculated to reveal the variations in intermolecular interactions. Subsequently, the formation of intermolecular hydrogen bonds, primarily characterized by H 2 O···HNH- interactions, had been further confirmed through spectroscopic analyses, including Fourier-transform infrared (FTIR) and Raman spectroscopy. The CO 2 absorption performance of different mixed system was systematically investigated under varying gas flow rates and water concentrations. The results demonstrated that the mixed system with higher water content exhibited optimal CO 2 absorption capacity at elevated gas flow rates, reaching a maximum absorption of 1.11 mol CO 2 /mol AEEA. Cyclic absorption experiments were further conducted, and graphic characterizations, including Raman spectroscopy, infrared spectroscopy, and 13 C NMR, were utilized to analyze the CO 2 absorption process of the H 2 O + (PEG300 + AEEA) mixed system over time. It was found that the byproducts N-hydroxyethyl-2-imidazolidinone (HEIA) and 3-(2-hydroxyethyl)-2-oxazolidinone (HEOD), formed during the cycles, were the primary contributors to the decline in absorption capacity. As the number of cycles increased, the mixed system gradually reached a new chemical equilibrium, with absorption performance stabilizing. These findings offered valuable theoretical insight for the optimization of absorbent systems.
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JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
·
2023
·Vol. 148
·期 14
·7259-7267
·
IF 4.4
Tian Wenshuang,Xiao Yang,Zhou Beiting,Qin Guangzhao,Zheng Xiong
As a new type of green solvent, deep eutectic solvents (DESs) are regarded as substitutes for ionic liquids in various applications, so the study of thermophysical properties of DESs is of great importance for their applications. In this work, DESs containing triethylene glycol as hydrogen bonding donor and choline chloride (ChCl) as hydrogen bond acceptor were synthesized in a series of molar ratios, and the thermal conductivity, viscosity, and density were investigated systematically. The addition of ChCl suppresses the thermal conductivity of DESs, but increases the viscosity and density, and the mechanism of the dependence of the thermophysical properties on the molar fraction is analyzed. The increase in the temperature always causes a decrease in the viscosity and density, while the thermal conductivity and temperature show a parabola dependence. Besides, the increase in the pressure results in the enhancement of thermal conductivity. Moreover, the thermophysical properties of DESs are fitted into correlations, and the AADs and MDs from fitted values and experimental data are 0.39% and 2.14% for thermal conductivity, 1.34% and 2.49% for viscosity, and 0.04% and 0.11% for density, respectively.
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Biomass Conversion and Biorefinery
·
2023
·
IF 4
Zhang Hao,Zhang Xia,Li Wenzhi,Wu Wenjian,Tang Bingyue,Zhu Chen
Efficient extraction of lignin from intricate lignocellulose is a challenge for the high-value utilization of lignocellulosic biomass in sustainable biorefinery. In this work, a p -toluene sulfonic acid-coupling ethylene glycol (PTSA/EG) pretreatment was developed to extract lignin from cornstalks. The results showed that the synergistic effect between p -toluene sulfonic acid and ethylene glycol resulted in an increase in the delignification ratio from 43.43 to 85.37% compared with PTSA aqueous pretreatment. When the concentration of PTSA was 5 wt.%, the delignification ratio reached 85.37% at 383.15 K under the PTSA/EG pretreatment. Moreover, the lignin fractions obtained by water precipitation have high purity (>90%) and a low molecular weight (1777~2271 Da). The fractionated lignin was depolymerized with Ru/C catalyst and methanol at 508.15 K for 3 h. When the pretreatment temperature is 368.15 K, the fractionated lignin has a good depolymerization performance, and the detected monomers yield reaches 17.46%. Overall, pretreatment using PTSA and EG could realize the disruption of the degradation barrier of lignocellulose and fractionate lignin with specific structures by adjusting the pretreatment conditions, which was conducive to commercial applications in biomass refining.
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CELLULOSE
·
2023
·Vol. 30
·期 5
·3061-3072
·
IF 5.7
Li Wei,Du Wenqing,Li Wenbin,Chen Dongzhi,Liu Yang,Ouyang Yiwei
In this work, the hygrothermal aging behavior, finite element analysis and mechanical properties of the ramie fiber (RF) reinforced polyethylene terephthalate glycol (PETG) composites modified with silane coupling agent and carbon nanotubes (CNTs) were investigated. The results show that after 90-days hygrothermal aging, the RF/PETG composites with untreated, KH550-treated, 0.5% CNT-treated and 1.0% CNT-treated modifications have the low water uptakes of 4.55%, 4.36%, 4.30% and 4.15%, respectively. The surface modifications of ramie fibers have no obvious influence on the water uptakes of the RF/PETG composites, which is related to the hydrophilicity difference of surface and cross sections of the RF/PETG composites. The moisture absorption behaviors of the RF/PETG composites conform to Fick’s water diffusion law. The results of the finite element analysis of the RF/PETG composites show a good consistency with the experimental results of the water absorption. As compared with untreated composites, the bending strengths of RF/PETG composites modified with silane coupling agent, 0.5 wt% CNTs and 1.0 wt% CNTs increased with 8.5%, 16.9%, and 20.5%, respectively. The bending strength and modulus of the RF/PETG composites first rapidly decrease and then slowly decrease with the increase of aging time. The RF/PETG composites show different bending fracture behaviors before and after 90-days hygrothermal aging. The developed RF/PETG composites have low water absorption and good mechanical properties, which can broaden the research and application of ramie fiber reinforced composites.
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COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
·
2023
·
IF 8.7
Yabi Yang,Shuang Liu,Guoliang Zhang,Ziqing Hu,Liang Jin,Bingqing Quan,Xiaoyun Hao,Hao Wu,Xiaofan Ji,Xiang Lu
The design of cellulose nanofiber (CNF)-encapsulated polyethylene glycol (PEG)-based phase change composites (PCCs) has shown great promise toward overcoming the phase transition process’s leakage. Whereas, the leakage is inescapable for intricate industrial occasions such as extrusion and collision. Thereby it’s requisite to monitor the products’ leakage. Herein, a fluorophore with aggregation-induced emission (AIE) effect was employed to prepare fluorescent PCCs. In detail, Pmix2 was picked to dip into the skeleton CNF6 to construct CNF6/Pmix2 with dim green. What’s more, the free fall of 500 g weight, 983 times of CNF6/Pmix2′s weight, was applied to the materials to simulate the possible force that occurred in real industrial processes. Obviously, CNF6/Pmix2′s leakage is seen on dark occasions, whereas CNF6/PEG’s leakage trace is hardly observed, evidencing CNF6/Pmix2 possesses the capacity of monitoring leakage. Additionally, CNF6/Pmix2 displays excellent thermal energy storage and reusability, illustrating promising energy conversion and storage applications.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Haifan Wang,Menglei Yuan,Jingxian Zhang,Yiling Bai,Ke Zhang,Bin Li,Guangjin Zhang
Ammonia (NH 3 ) synthesis at mild conditions by electrocatalytic nitrogen reduction (eNRR) has received more attention and has been regarded as a promising alternative to the traditional Haber–Bosch process. Lewis acid-base pairs (LPs) can chemisorb and react with nitrogen by electronic interaction, while the tuning of the microenvironment near electrode can hinder hydrogen evolution reaction (HER) thus improving the selectivity of the eNRR. Herein, the FeOOH nanorod coupled with LPs on the surface (i.e., Fe, Fe–O) was synthesized, which could effectively drive eNRR. Meanwhile, polyethylene glycol (PEG) was introduced to serve as a local non-aqueous electrolyte system to inhibit HER . The prepared FeOOH-150 catalyst achieved outstanding eNRR performance with an NH 3 yield rate of 118.07 μg h −1 mg cat −1 and a Faradaic efficiency of 51.4 % at −0.6 V vs. RHE in 0.1 M LiClO 4 + 20 % PEG . Both the experiment and DFT calculations revealed that the interaction of PEG with Lewis base sites could optimize nitrogen adsorption configuration and activation.
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Polymers
·
2022
·Vol. 14
·期 21
·4694
·
IF 4.967
Ran Yu,Chao Xu,Xiaopei Wu,Honglian Dai
We designed and synthesized the polyoxyethylene diamine (H2N-PEG-NH2) and poly(amide-imide)-polyethylene glycol (PAI-PEG) copolymers. The physical and chemical properties, mechanical properties, and in vitro biocompatibility of the materials were characterized. The results showed that the best elongation at break and recovery were obtained when the amount of PEG was 5 wt%. With the increase in PEG content, the degradation rate, hydrophilic property, tensile strength and tensile modulus of the copolymer decreased to a certain extent. The material had the best thermal stability and mechanical properties when 5 wt% PEG was added. Cytocompatibility evaluation showed that the addition of PEG could enhance the cell compatibility of the material and make it potentially suitable for application in bone repair.Keywords:polyoxyethylene diamine (H2N-PEG-NH2);poly(amide-imide) (PAI);biocompatibility
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高影响因子
JOURNAL OF POLYMER SCIENCE
·
2022
·Vol. 61
·期 3
·251-261
·
IF 3.046
Cui Yang,Zhong-Sen Ma,He-Wen Zhi,Hao Li,Ye-Min Hu,Ya-Jie Zhang
Bio-based 2,5-furandicarboxylic acid (FDCA) can be used to produce poly(ethylene 2,5-furandicarboxylate) (PEF), which has a great potential for barrier packaging, and so forth. Herein, the first two steps of the esterification reaction of FDCA with ethylene glycol (EG) were investigated. The dissolution rate of FDCA in EG is fast, the solubility of FDCA in EG and monohydroxyethyl 2,5-furandicarboxylate (MHEF) reaches 159.12 and 489.84 g kg −1 at 180 °C, respectively. The initial esterification of FDCA with EG to form MHEF is a zero-order reaction ( k 1 = 266.77 × 10 −3 mol kg −1 min −1 ) with an activation energy of 114.52 kJ mol −1 ; the esterification of MHEF with EG to form bis(hydroxyethyl) 2,5-furandicarboxylate (BHEF) is a first-order reaction ( k 2 = 9.72 × 10 −3 min −1 ) with an activation energy of 86.12 kJ mol −1 . These results identified accurate parameters for the dissolution and esterification processes of FDCA in EG, which provide important guidance for the polymerization of FDCA polyesters. Graphical
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ENERGY CONVERSION AND MANAGEMENT
·
2022
·
IF 11.533
Chaoming Wang,Zheng Huang,Tingjun Wang,Xing Liu,Peng Zhu
Organic phase change materials (PCMs) based latent heat energy storage and release media are promising candidate for the utilization of thermal energy from the solar irradiation. However, the poor photo-absorption ability and intrinsic poor thermal conductivity of organic PCMs results in leakage problem and slow thermal energy charging/discharging rates, which makes them unable to utilize directly for thermal energy conversion. Herein, we fabricate a three-dimensional (3D) carboxymethylcellulose sodium-derived carbon aerogel (CCA) and organic PCM composite with highly efficient light-thermal-electric energy conversion and storage capability. The porous and interconnected CCA15 is prepared firstly through crosslinking, freeze-drying and pyrolysis of carboxymethylcellulose sodium-based hydrogel. The organic PCM of polyethylene glycol (PEG) is then impregnated into the porous CCA15 via vacuum infiltration technique to obtain the PEG/CCA15 composite that had good form-stability, fusion enthalpy at 185.3 J/g, thermal conductivity at 0.351 W/m·K, and reasonable light-thermal energy conversion efficiency of 71.5% under solar irradiation with intensity of 215 mW/cm 2 . Further results proved that the PEG/CCA15 composite exhibited light-electric energy transformation, storage, and release abilities. The stored thermal energy in the PEG/CCA15 composite absorbed from irradiated solar light could release to power an electronic fan to rotate continuously for 5 min when the solar light was turned off. Hence, the PEG/CCA15 composite has great potential for sustainable solar energy utilization.
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JOURNAL OF SURFACTANTS AND DETERGENTS
·
2022
·Vol. 25
·期 5
·643-654
·
IF 1.972
Yu Zhao,Chenyu Liu,Hailiang Chen,Hengjun Zhou,Simiao Yu,Deze Mi,Shuli Yue,Weihong Qiao
Liposomes are the predominant drug delivery system widely used in the pharmaceutical industry, but rapid clearance and endosome degradation are the main barriers to improve the delivery efficiency of liposomes, especially for protein or genes. Simulating viral membrane fusion peptides, four asymmetrically dihydrophobic chain polyethylene glycol (PEG) lipids with long circulating and membrane fusion properties have been designed and synthesized with a high yield. The structure of synthetic PEG lipids is characterized by 1 H NMR and mass spectrometry. The critical micelle concentrations of PEG lipids are lower by one or two orders of magnitude compared with traditional surfactants such as SDBS or SDS, which show excellent self-assembly performance of lipids. The size and morphology of liposomes constituted with neutral lipid DOPC and PEG lipid are characterized by dynamic light scattering (DLS) and transmission electron microscopy (TEM). In the conditions of 50% ethanol and 5–25 mmol L −1 Ca 2+ , the PEG neutral lipid complexes encapsulated pEGFP are almost neutral with a diameter below 300 nm.
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