Advanced Healthcare Materials
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2024
·
IF 10
Anyi Dao,Shiyan Chen,Li Pan,Qingyan Ren,Xun Wang,Haorui Wu,Qiufang Gong,Zeduan Chen,Shaomin Ji,Jiaxi Ru,HaoTu Zhu,Chao Liang,Pingyu Zhang,Haiping Xia,Huaiyi Huang
Photoactivable chemotherapy (PACT) using metallic complexes provides spatiotemporal selectivity over drug activation for targeted anticancer therapy. However, the poor absorption in near-infrared (NIR) light region of most metallic complexes renders tissue penetration challenging. Herein, an NIR light triggered dinuclear photoactivable Ru(II) complex ( Ru2 ) is presented and the antitumor mechanism is comprehensively investigated. The introduction of a donor–acceptor–donor (D–A–D) linker greatly enhances the intramolecular charge transition, resulting in a high molar extinction coefficient in the NIR region with an extended triplet excited state lifetime. Most importantly, when activated by 700 nm NIR light, Ru2 exhibits unique slow photodissociation kinetics that facilitates synergistic photosensitization and photocatalytic activity to destroy diverse intracellular biomolecules. In vitro and in vivo experiments show that when activated by 700 nm NIR light, Ru2 exhibits nanomolar photocytotoxicity toward 4T1 cancer cells via the induction of calcium overload and endoplasmic reticulum (ER) stress. These findings provide a robust foundation for the development of NIR-activated Ru(II) PACT complexes for phototherapeutic application.
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高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Kang Deng,Xintong You,Minyi Liu,Yongyi Tan,Yilian Lin,Wei Shu,Feiyan Liu,Shunheng Tu,Yi Yang
Herein, we developed a self-assembly heterostructured BiOI/Bi 4 O 5 Br 2 microcluster with the hydrothermal method . Catalysts were mainly characterized by powder X-ray diffraction, field-emission scanning electron microscopy, transmission electron microscope , energy dispersive X-ray spectroscopy, X-ray photoelectron spectroscopy and diffuse reflectance spectra. The results showed that due to charge induction, BiOI nanosheets were successfully self-assembled and deposited on Bi 4 O 5 Br 2 , forming a unique heterojunction and achieving strong transient photocurrent response. Performances of catalysts were tested and effects of different initial concentrations of the Methylparaben (MPB), catalyst dosage, initial pH and total organic carbon (TOC) conversion were studied. Results reveal that catalytic activity increased with lower initial concentration of MPB and the best dosage of catalyst is 0.5 g·L -1 . The BiOI/Bi 4 O 5 Br 2 microcluster exhibits excellent photocatalytic activity under visible-light irradiation, which can degrade 97% MPB in 2 h and the TOC value is only 20% of the original. The catalytic degradation process conforms to pseudo-first-order kinetics with a rate constant of 0.030 min -1 . The results of detailed active species detection indicate that the photogenerated holes and •O 2 − radicals play the main role in the photocatalytic system. In addition, photoelectrochemical measurements reveal that the excellent strengthened photocatalytic activity is due to the high separation and transfer efficiency derived from the heterostructure.
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MICROCHEMICAL JOURNAL
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2024
·
IF 4.9
Xue Zhen Dong,Tai Yi Zhang,Yu Rong Guo,Nian Bing Li,Hong Qun Luo
Inorganic phosphate (Pi) not only sustains the physiological functions within organisms but also acts as an indicator of environmental water pollution. Thus, it is extremely significant to seek out a rapid and straightforward method for detecting Pi. In this paper, the lanthanide metal luminescent nanomaterial europium-pyromellitic acid (Eu-PMA, exhibiting characteristic fluorescence emission at 435 nm for PMA and 617 nm for Eu 3+ ) is synthesized via a simple solvothermal approach and utilized as a probe for ratiometric fluorescence detection of Pi. As the amount of Pi increases, Pi has a strong complexation ability with ligand PMA, resulting in the structural damage of Eu-PMA. PMA cannot sensitize Eu 3+ luminescence, thus the fluorescence intensity at 617 nm of the system is markedly decreased. Meanwhile, through energy transfer interaction, the fluorescence intensity at 435 nm of ligand PMA is weakly increased. Based on the ratio of the changes in fluorescence intensities of the two, a ratiometric fluorescence method is established for the detection of Pi. The method is not only rapid and simple, but also improves the sensitivity of Pi detection (Linear range is 0.1–90 μM). Moreover, the content of Pi in actual water samples has been analyzed and determined successfully by this method, which further broads the significance and application prospect of the ratiometric fluorescence method in detecting Pi.
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Inorganic Chemistry Frontiers
·
2024
·Vol. 11
·期 18
·6044-6051
·
IF 6.1
Kunhong Li,Yumei Hong,Xinyi Ma,Yujie Zhao,Shihao Zhang,Pengtao Ma,Jingyang Niu,Jingping Wang
Photocatalytic carbon dioxide reduction is considered an important strategy to solve environmental problems, such as greenhouse gases, but designing and synthesizing effective photocatalysts is a challenge. In recent years, photocatalytic carbon dioxide reduction by polyoxometalates (POMs) has attracted increasing research interest. Herein, the first purely inorganic ruthenium–germanium–molybdenum–oxygen cluster, Na12Rb2[Ru2O2(GeMo10O36)2]·44H2O (Ru2Ge2Mo20), was synthesized by hydrothermal and volatilization methods and applied to photocatalytic carbon dioxide reduction. The yield of CH4 reached 547.84 μmol g−1 in the heterogeneous photocatalytic reaction system with an electron selectivity of 96.86% with respect to CO (71.08 μmol g−1) after 6 h. The reaction mechanism was confirmed by UV-Vis diffuse reflection spectroscopy, ultraviolet photoelectron spectroscopy (UPS), electrochemical measurements, and steady-state fluorescence quenching experiments. This work provides a reference for the design of Ru-containing polyoxometalates for photocatalytic CO2 reduction.
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ACS Materials Letters
·
2024
·
IF 9.6
Ruo-Yin Meng,Ying Zhao,Hong-Ying Xia,Shi-Bin Wang,Ai-Zheng Chen,Ranjith Kumar Kankala
The complexity of the cancer microenvironment makes it highly challenging for drugs to meet therapeutic requirements, significantly hampering their clinical translation. The enormous potential of intelligent materials that can act as drugs themselves results in the development of smart drugless or drug-like architectures, offering synergistic therapeutic effects. In this study, we demonstrate the generation of transition metal-based dichalcogenides (TMDCs)-based conformational (flower-like) nanoarchitectonics for synergistic trimodal therapies against breast carcinoma. Initially, the progressive transformation of two-dimensional (2D) molybdenum selenide (MoSe2)-based nanosheets into nanoflower-like architectures by the thermal injection method is observed with time. Further, these flowers are subsequently decorated with an optimal amount of platinum (Pt) nanoparticles for nanocatalytic efficacy and surface-modified with polyethylene glycol (PEG) for improved biocompatibility, shortly denoted as Pt-MoSe2-PEG for light-assisted photothermal (PTT) and photodynamic (PDT), as well as light-augmented chemodynamic (CDT) modalities. A series of physicochemical characterizations and performance validations successfully demonstrated the generation of tumor (pH/GSH)-responsive degradable nanoflower-like structures, substantially improving their ability of reactive oxygen species generation, MoSe2-based PTT/PDT capability, and light-augmented CDT efficacy of the Pt nanoenzymes. Finally, in vitro and in vivo investigations in the 4T1 cell line and its xenograft tumor model in BALB/C mice, respectively, validated the synergistic trimodal therapies of Pt-MoSe2-PEG toward ablating breast carcinoma.
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APPLIED SURFACE SCIENCE
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2011
·
IF 1.795
Segomotso Bagwasi,Baozhu Tian,Feng Chen,Jinlong Zhang
Iodine doped titanium dioxide has been successfully prepared by simple hydrolysis of tetrabutyl titanate in the presence of iodic acid. The adopted method allowed for the production of spherical iodine doped titaniun dioxide nanoparticles with varied amount of iodine content. Analysis by X-ray diffraction, Raman, transmission electron microscopy as well as UV–vis DRS revealed that titanium dioxide nanostructures were doped with iodine which existed in two different valence states I 5+ and I − . The iodine in the form of I 5+ is believed to have doped into the lattice whereas I − was well dispersed on the surface of TiO 2 probably as iodine adducts hence rendering it to be highly absorbing in visible light region. The I-TiO 2 exhibited improved photocatalytic activity toward degradation of acid orange 7 (AO7), methyl orange (MO) and 2,4-dichlorophenol (2,4-DCP) under visible light over the pristine TiO 2 prepared by the same method. High catalytic properties are attributed to iodine doping which led to high specific surface area, absorption in visible region as well as alleviation of charge carrier recombination. The most probable route undertaken in the degradation of AO7 is through indirect oxidation by the hydroxyl radicals.
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Inorganic Chemistry Frontiers
·
2017
·Vol. 4
·期 7
·1166-1172
·
IF 4.036
Qinqin Ma,Jie Wang,Zhiheng Li,Dong Wang,Xiaoxia Hu,Yisheng Xu,Quan Yuan
Information security has attracted broad attention in today's information age, and information encryption on paper has been widely studied since paper is still the most important information carrier. Fluorescent inks are commonly used in information encryption on paper, but they suffer from background fluorescence interference. Herein, we develop a background-free and easy-to-perform method for information encryption based on the inkjet printing of upconversion nanoparticles (UCNPs). The UCNPs can efficiently eliminate background fluorescence interference since phosphors in paper cannot be activated by near-infrared (NIR) light. Moreover, owing to their small size, excellent dispersibility and good stability, UCNP inks can be directly applied to commercial inkjet printers for convenient and high-throughput information encryption on paper. Information was easily printed on different kinds of paper substrates and the information can only be visualized under NIR light excitation. Furthermore, a novel information encryption strategy was designed by utilizing UCNPs with different excitation wavelengths. Only excitation at the defined wavelength can obtain the correct information. This proposed information encryption strategy can completely avoid background fluorescence interference, and it also features easy operation, high throughput as well as low costs, indicating its good promise to serve as a household encryption method in our daily life.
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RSC Advances
·
2017
·Vol. 7
·期 64
·40673-40681
·
IF 3.108
Xinlin Liu,Yingying Qin,Yongsheng Yan,Peng Lv
A magnetic photocatalyst, CdS/CoFe2O4/rGO, has been successfully prepared via a simple hydrothermal method. The photocatalytic activity of the as-obtained composite photocatalyst was evaluated using the degradation of tetracycline. When compared with single CdS and CoFe2O4, the hybrid material (CdS/CoFe2O4/rGO) can enhance the photocatalytic activity. The photocurrent responses and PL spectra indicate that the composite photocatalyst can effectively separate the electron–hole pairs and restrain their recombination. This was attributed to the high charge carrier mobility of rGO and the heterostructured photocatalytic system, which promotes the separation of charge carriers. In all, the CdS/CoFe2O4/rGO photocatalyst, as a strong magnetic photocatalyst, is promising for further practical application in wastewater treatment.
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JOURNAL OF NANOPARTICLE RESEARCH
·
2017
·Vol. 19
·期 5
·1-11
·
IF 2.02
Feng Jiantao,Wang Yechen,Hou Yanhui,Li Liangchao
Hierarchical structured ZnFe 2 O 4 @reduced graphite oxide@TiO 2 (ZnFe 2 O 4 @RGO@TiO 2 ) nanocomposite was prepared by an electrostatic layer-by-layer route, which played a synthetic effect of Fenton oxidation of ZnFe 2 O 4 and photocatalytic oxidation of TiO 2 to degrade fulvic acid (FA) solution under visible-light irradiation. In this method, RGO, as the middle layer, can effectively promote the photo-induced electron flow between the ZnFe 2 O 4 and TiO 2 and further improve the efficiency of the photo-Fenton oxidation. The influencing factors on photo-Fenton oxidation, including solution pH, catalyst, and H 2 O 2 dosage, have also been investigated. The results illustrated that the ternary composite presented the enhanced catalytic performance. Under visible light irradiation, the degradation efficiency of the sample on the FA solution can reach 95.4% within 3 h. In addition, the catalyst exhibited superior stability and reusability, and its degradation efficiency was still up to 90% after 5 cycles. Therefore, the composite will be a kind of efficient photocatalyst and had a promising application for visible-light driven destruction of organic pollutants.
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JOURNAL OF POROUS MATERIALS
·
2017
·Vol. 25
·期 1
·189-198
·
IF 1.624
Feng Zhouzhou,Lv Xiang,Wang Tianhe
TiO 2 porous ceramic/Ag–AgCl composite was prepared by incorporating AgCl nanoparticles within the bulk of TiO 2 porous ceramic followed by reducing Ag + in the AgCl particles to Ag 0 species under visible light irradiation. The porous TiO 2 ceramic was physically robust and chemically durable, and the porous structure facilitated the implantation of AgCl NPs. Compared with the bare TiO 2 ceramic, TiO 2 porous ceramic/Ag–AgCl composite exhibited higher photocatalytic performance for the degradation of MO and RhB under visible light irradiation. The reaction rate constants k of MO and RhB degradation over TiO 2 porous ceramic/Ag–AgCl composite was respectively 6.25 times and 3.62 times higher than those recorded over the bare TiO 2 porous ceramic. The photocatalytic activity showed virtually no decline after four times cyclic experiments under visible light irradiation. Scanning electron microscopy, energy dispersive X-ray analysis, X-ray diffraction, UV–Vis diffuse reflectance spectroscopy, photoluminescence spectra and X-ray photoelectron spectroscopy were used to characterize the TiO 2 porous ceramic/Ag–AgCl composite.
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ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Yuanlong Huang,Jiaxing Zhu,Jinghui Li,Jiajun Luo,Peipei Du,Boxiang Song,Jiang Tang
Perovskite light-emitting diodes (PeLEDs) have shown great potential in the display domain due to their wide color gamut, narrow emission, and low cost. In current PeLEDs manufacturing methods, thermal evaporation shows great competitiveness with its advantages of easy patterning, production line compatibility, and solvent-free processability. However, the development of thermally evaporated blue PeLEDs is limited by their low radiative recombination rate and high defect density. Herein, we report high-performance thermally evaporated blue PeLEDs by in situ introduction of ammonium cations. We confirm that phenethylammonium (PEA+) has lower adsorption energy, which significantly reduces the low-n phases in a quasi-2D perovskite film. The energy transfer rate is also promoted by the PEA+ addition. As a result, we fabricate blue PeLEDs with an external quantum efficiency of 1.56% by thermal evaporation. The strategy of arranging phase distribution could benefit the industrialization of full-color PeLEDs.
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ENERGY
·
2024
·
IF 9
Pengcheng Li,Dantong Wang,Yaoqi Hou,Zhan Hu,Danqing Chen,Yi Wang,Chunfeng Song
CO 2 absorption-microalgae conversion (CAMC) system can be a sustainable technology to achieve low-energy carbon capture and resource utilization in response to zero carbon. However, light stress could restrict the carbon utilization efficiency of CAMC system. In this study, melatonin (MT) and indole-propionic acid (IPA) as phytohormones, were used to promote the carbon fixation capacity and biomass yield of CAMC system under light stress, and the potential mechanism was also discussed. Both MT and IPA promoted the growth of Spirulina , and 10 mg-MT group obtained the highest biomass and carbon fixation capacity, which were 27.61 % and 30.62 % higher than control. MT and IPA promoted the activity of superoxide dismutase (SOD), catalase (CAT), and glutathione reductase (GR), enhancing antioxidant activity to avoid oxidative damage. The results of transmission electron microscopy (TEM) and cell apoptosis showed MT and IPA reduced cell membrane damage and apoptosis. Phytohormones induced the carbon flux flow to the synthesis of carbohydrate and protein, and increased carbohydrate and protein productivity. Moreover, the maximum phycocyanin content and yield were 13.74 % and 43.25 % higher than the control. Therefore, adding phytohormones was an effective strategy to achieve high-value bioresources of microalgae in CAMC system under light stress.
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