EUROPEAN FOOD RESEARCH AND TECHNOLOGY
·
2023
·Vol. 249
·期 12
·3097-3103
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IF 3.3
Li Yangyang,Zhu Zhengwei,Qu Wenli,Yang Qing,Liu Yan,Wang Qiao,Duan Shuo,Wu Jine,Gong Zhiyong,Xu Lin
Lead ions are a toxic metal that can enter the human body through the diet and negatively impact human health. A wide variety of foods, such as vegetables, meat, aquatic product, and drinking water, can be contaminated with lead ions. In this study, a highly sensitive immunochromatographic assay (ICA) based on antibody-oriented probe and silver enhancement was established for the qualitative and quantitative determination of lead ions in drinking water. The recombinant protein A (PrA) was used in probe preparation to improve antibody bioactivity while silver enhancement method was applied to enhance the signal reporter of ICA. It was determined that the visual limit of detection and the scanning limit of quantification of the ICA based on antibody-oriented probe and silver enhancement for lead ions in drinking water were 0.2 ng/mL and 0.08 ng/mL, respectively. The results obtained from developed ICA strip and ICP-MS had no obvious difference using statistical analysis of t test. Compared to previously reported ICA methods for lead ions, the developed ICA method enabled analyzing lead ions in drinking water with a superior sensitivity and detection range.
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Nature Communications
·
2023
·Vol. 14
·期 1
·1-14
·
IF 16.6
Li Caicong,Cheng Jianxiang,He Yunfeng,He Xiangnan,Xu Ziyi,Ge Qi,Yang Canhui
Stretchable ionotronics have drawn increasing attention during the past decade, enabling myriad applications in engineering and biomedicine. However, existing ionotronic sensors suffer from limited sensing capabilities due to simple device structures and poor stability due to the leakage of ingredients. In this study, we rationally design and fabricate a plethora of architected leakage-free ionotronic sensors with multi-mode sensing capabilities, using DLP-based 3D printing and a polyelectrolyte elastomer. We synthesize a photo-polymerizable ionic monomer for the polyelectrolyte elastomer, which is stretchable, transparent, ionically conductive, thermally stable, and leakage-resistant. The printed sensors possess robust interfaces and extraordinary long-term stability. The multi-material 3D printing allows high flexibility in structural design, enabling the sensing of tension, compression, shear, and torsion, with on-demand tailorable sensitivities through elaborate programming of device architectures. Furthermore, we fabricate integrated ionotronic sensors that can perceive different mechanical stimuli simultaneously without mutual signal interferences. We demonstrate a sensing kit consisting of four shear sensors and one compressive sensor, and connect it to a remote-control system that is programmed to wirelessly control the flight of a drone. Multi-material 3D printing of leakage-free polyelectrolyte elastomers paves new avenues for manufacturing stretchable ionotronics by resolving the deficiencies of stability and functionalities simultaneously.
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Science China-Technological Sciences
·
2023
·
IF 4.6
Li MingWen,Tang Chen,Yu XiXi,Shi XinLei,Yu Hui,Yin HaiYan,You Min,Chen Qiang,Ding Xi
The arch wire (AW) plays an important role in providing continuous force, aligning the teeth, and excellent dental arch stability for orthodontic treatment. However, the high friction performance of the AW surface can increase bacterial adhesion and colonization, leading to oral hygiene problems. Herein, a simple method is developed to modify the surface of the orthodontic wire with a poly(vinyl alcohol) (PVA) hydrogel coating, which can improve the lubricity and antibacterial adhesion of the AW and prevent the oral hygiene problems caused by itself. The PVA hydrogel coating can toughly adhere to the surface of the AW and remarkably reduce the friction performance of the AW, and then its friction coefficient in water can reach 0.005. Under the action of brushing and bending, the PVA hydrogel coating possesses superior ultralubrication and hardly affects the mechanical properties of the stainless-steel substrate. Moreover, the PVA hydrogel coating can significantly inhibit bacterial adhesion on the surface of the AW, thereby reducing bacterial colonization and maintaining oral hygiene while correcting the shape of the mouth and jaw. Therefore, the PVA hydrogel coating exhibits tough adhesion and good antibacterial adhesion while maintaining the mechanical properties of the AW, and it is a promising antifouling coating for improving the performance of the AW.
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Advanced Fiber Materials
·
2023
·
IF 16.1
Yuan Zhengchao,Zhao Yue,Shafiq Muhammad,Song Jiahui,Hou Jing,Liang Yuqing,Yu Xiao,Chen Yujie,Yu Fan,EL-Newehy Mohamed,EL-Hamshary Hany,Morsi Yosry,Jiang Shichao,Zheng Hui,Mo Xiumei
Abstract As one of the most common forms of skin injuries, skin burns are often accompanied by edema pain, suppuration of infection, slow tissue regeneration, and severe scar formation, which significantly delay wound healing as well as affect the quality of life. We prepared multifunctional electrospun poly(L-lactide-co-glycolide)/gelatin (P/G)-based dressings to synergistically harness the therapeutic benefits of peppermint essential oil (T), burn ointment (B), and Oregano essential oil (O) (P/G@TBO) for skin regeneration in punch and burn injury models. The P/G@TBO can afford the sustained release of bioactive cues for up to 72 h as well as remarkably promote cell migration ( ca. P/G@TBO, 89% vs. control group, 51%) at 24 h. The P/G@TBO membranes also showed significant angiogenic effect as well as antibacterial and anti-inflammatory properties than that of the control group in vitro. Moreover, P/G@TBO dressings enabled fast wound healing ( ca. P/G@TBO, 100% wound closure vs. control group, 95%) in a full-thickness excisional defect model up to 14 days in rats. Further evaluation of membranes in different animal models, including tail wagging model, facial itch model, and hot burn injury model showed significant pain relieve effect as well as itching and swelling relief functions during earlier stages of wound healing. Membranes were next transplanted into a scalded wound model in rats and an ear punch wound model in rabbits, which manifested antibacterial and anti-inflammatory properties and promoted re-epithelialization to achieve scarless wound healing percentage wound closure at day 28: P/G@TBO, 96% vs. control group 66%. Taken together our approach of simultaneously harnessing T, B, and O to enable multifunctionality to fibrous dressings may hold great promise for burn wound healing applications and other related disciplines. Graphical abstract
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NATURE
·
2023
·Vol. 621
·期 7979
·511-515
·
IF 64.8
Yang Guangxu,Gong Zhenggang,Luo Xiaolin,Chen Lihui,Shuai Li
Plywood is widely used in construction, such as for flooring and interior walls, as well as in the manufacture of household items such as furniture and cabinets. Such items are made of wood veneers that are bonded together with adhesives such as urea–formaldehyde and phenol–formaldehyde resins 1 , 2 . Researchers in academia and industry have long aimed to synthesize lignin–phenol–formaldehyde resin adhesives using biomass-derived lignin, a phenolic polymer that can be used to substitute the petroleum-derived phenol 3 , 4 , 5 , 6 . However, lignin–phenol–formaldehyde resin adhesives are less attractive to plywood manufacturers than urea–formaldehyde and phenol–formaldehyde resins owing to their appearance and cost. Here we report a simple and practical strategy for preparing lignin-based wood adhesives from lignocellulosic biomass. Our strategy involves separation of uncondensed or slightly condensed lignins from biomass followed by direct application of a suspension of the lignin and water as an adhesive on wood veneers. Plywood products with superior performances could be prepared with such lignin adhesives at a wide range of hot-pressing temperatures, enabling the use of these adhesives as promising alternatives to traditional wood adhesives in different market segments. Mechanistic studies indicate that the adhesion mechanism of such lignin adhesives may involve softening of lignin by water, filling of vessels with softened lignin and crosslinking of lignins in adhesives with those in the cell wall.
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POLYMER BULLETIN
·
2023
·
IF 3.2
Faqir Yahya,Chai Yunlong,Jakhar Ali Murad,Wu Sanmei,Luo Tong,Liao Shiyu,Kalhoro Mohammad Talib,Li Linqiu,Kaleri Abdul Rasheed,Tan Chengjia,Ma Jiahua,Zhang Qiling,Cao Shidong,Adeel Mohammad
The present study was undertaken with the aim of evaluating the ginger essential oil potential and its urea-loading efficacy in the preparation of control-releasing chitosan microspheres. The ginger oil for hydro-distillation was extracted by applying Clevenger apparatus, chemical composition was characterized by FTIR, and the GC-MS was used to identify the oil compounds. Urea-loaded chitosan microsphere formulations were formulated through modified emulsification and cross-linking procedure. The various factors and levels related to preparation of urea-loaded chitosan microspheres were evaluated using response surface test. The present study was also an effort to observe the yield and content of nitrogen. Additionally, FTIR and SEM were applied to characterize the microspheres. The results show the yield of ginger oil as 6.0%. Main compounds identified by GC-MS were gingerol, decanal, isoshogaol, octanal, and others. FTIR also showed that some typical bands appeared in ginger oil. The nitrogen content % in urea-loaded microspheres showed a significantly higher value in proportion to higher oil volume and cross-linking. However, by decreasing the amount of urea and enhancing acetic acid, nitrogen content was decreased. The lower oil concentrations improved the microsphere surface structure and morphology. Response surface analysis showed that the optimum preparation conditions are as follows: 2.094% of Span 80, 2.302% of acetic acid, and cross-linking agent ratio of formaldehyde to glutaraldehyde 1:8.15. Under these conditions, the theoretical value of nitrogen content of urea-loaded chitosan microspheres was 4.683%. According to release test, the urea diffused uniformly in the microspheres after 48 h. It is concluded that the use of ginger oil in control release of fertilizers is the right option in the formulations of control-releasing micro-fertilizers.
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NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
·
2023
·
IF 3.6
Chen Min,Huang Shanjiao,Weng Shuoyun,Weng Junting,Guo Rongjie,Shi Bingbing,Liu Danjuan
Septic cardiomyopathy (SCM) is manifested by impairment of cardiac contractile function with myocardial mitochondrial dysregulation. Natural product, songorine (SGR), a diterpenoid alkaloid derived from the lateral root of Aconitum carmichaeli , has been reported for the treatment of heart failure. Here, the protective role of SGR in heart injury of SCM was investigated and its underlying action of mechanism was explored. Firstly, the mouse and cardiomyocytes (H9C2 cell) SCM model induced by LPS were established to evaluate the therapeutic effect of SGR. The in vivo results exhibited that SGR rescued the survival rate of SCM mice, restored the loss of ejection fraction (EF) and fractional shortening (FS), and reduced left ventricular systolic diameter and left ventricular diastole diameter (LVIDs, LVIDd) by echocardiography. SGR improved the mitochondrial biosynthesis and myocardial fiber structure and arranged them neatly by transmission electron microscope (TEM). Further, SGR inhibited inflammatory targets myeloperoxidase (MPO) and tumor necrosis factor (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6), and plasminogen activator inhibitor-1 (PAI-1). And SGR activated the mitochondrial biosynthesis–related peroxisome proliferator–activated receptor-γ coactivator-1α (PGC-1α), β-catenin, and matrix metallopeptidase 2 (MMP2) proteins. Meanwhile, the in vitro results showed that SGR promoted the increased the myocardial H9C2 cell viability, and mitochondrial biosynthesis and structure. SGR also blocked the inflammatory factors and reversed PGC-1α, β-catenin, and MMP2 in vitro, while SGR alleviated the myocardial cell apoptosis via flow cytometry. The findings indicate that SGR mitigates sepsis-caused myocardial damage by Wnt/β-catenin signaling pathway–mediated mitochondrial biosynthesis. SGR may be a promising candidate for treatment of SCM. Graphical Abstract
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Nano-Micro Letters
·
2023
·Vol. 15
·期 1
·1-12
·
IF 26.6
Zhou Bo,Du Aixuan,Ding Dong,Liu Zexiang,Wang Ye,Zhong Haizhe,Li Henan,Hu Hanlin,Shi Yumeng
Abstract Single materials that exhibit efficient and stable white-light emission are highly desirable for lighting applications. This paper reports a novel zero-dimensional perovskite, Rb 4 CdCl 6 :Sn 2 + , Mn 2 + , which demonstrates exceptional white-light properties including adjustable correlated color temperature, high color rendering index of up to 85, and near-unity photoluminescence quantum yield of 99%. Using a co-doping strategy involving Sn 2+ and Mn 2+ , cyan-orange dual-band emission with complementary spectral ranges is activated by the self-trapped excitons and d-d transitions of the Sn 2+ and Mn 2+ centers in the Rb 4 CdCl 6 host, respectively. Intriguingly, although Mn 2+ ions doped in Rb 4 CdCl 6 are difficult to excite, efficient Mn 2+ emission can be realized through an ultra-high-efficient energy transfer between Sn 2+ and Mn 2+ via the formation of adjacent exchange-coupled Sn–Mn pairs. Benefiting from this efficient Dexter energy transfer process, the dual emission shares the same optimal excitation wavelengths of the Sn 2+ centers and suppresses the non-radiative vibration relaxation significantly. Moreover, the relative intensities of the dual-emission components can be modulated flexibly by adjusting the fraction of the Sn 2+ ions to the Sn–Mn pairs. This co-doping approach involving short-range energy transfer represents a promising avenue for achieving high-quality white light within a single material.
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POLYMER BULLETIN
·
2023
·
IF 3.2
Zhu Fen,She Xiao,Huang Huabo,Zhang Zhanhui,Ji Jiayou,Li Liang
Stable polypyrrole (PPy)-based hydrogels as soft conducting materials are ideal in wearable electronics and elastic robotics. The development of high-performance PPy-based hydrogels is greatly desired due to the poor mechanical properties of PPy hydrogel. Here, multifunctional stable conducting hydrogels are fabricated by immersing the preprepared brittle PPy hydrogel into polyvinyl alcohol (PVA) solution followed by freeze–thaw cycles. The extensive hydrogen bonding between PPy and PVA and the entangled PVA chains further support the backbone structure of the interconnected PPy network, improving the mechanical performance of the hydrogel. PPy/PVA hydrogel exhibits attractive mechanical property with a compression strength of 70 kPa, satisfactory electrical conductivity (10 S m −1 ), good processability, and self-healing features. PPy/PVA/100 still retained a recovery rate of more than 90% even after 1000 cycles of 30% compression strain. Furthermore, the as-prepared hydrogel is applied to show high-quality electrochemical behavior of 120 F/g subjected to repeated compression and an electrically controlled release of fluorescein sodium with 0.70 μg/mg at − 1 V for 12 h. This facile method supplies a promising strategy to fabricate soft materials with integrated electrical and mechanical properties for the potential applications in wearable devices and flexible energy electronics.
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Advanced Fiber Materials
·
2023
·Vol. 5
·期 5
·1759-1772
·
IF 16.1
Zheng Yun,Man Zengming,Zhang Yang,Wu Guan,Lu Wangyang,Chen Wenxing
Stretchable supercapacitors (S-SCs) are of considerable interest as prospective energy-storage devices for wearable electronics and smart products. However, achieving high energy density and stable output under large deformations remains an urgent challenge. Here, we develop a high-performance S-SC based on a robust heterostructured graphene–polyaniline (G-PANI) anchored hierarchical fabric (G-PANI@pcPU). By precisely manipulating centrifugal electrospinning and PANI-induced two-step self-assembly process, the G-PANI@pcPU features an inter-linkage porous backbone, which open ions migration/intercalation pathways, high mechanical flexibility (elongation: 400%), and large production area (> 90 cm 2 ). The resultant G-PANI@pcPU presents ultra-large specific areal capacitance ( C areal ) of 5093.7 mF cm −2 (about 35 mg cm −2 mass loading of G-PANI) and redox reversibility in 1 M H 2 SO 4 electrolyte. Additionally, the G-PANI@pcPU fabric-based solid-state S-SCs show a high energy density of 69.2 μWh cm −2 and capacitance of 3113.7 mF cm −2 . More importantly, the superior stretchable stability (84.1% capacitance retentions after 5000 cycles) and foldable performance (86.7% capacitance retentions after 5000 cycles) of S-SCs are impressively achieved. Finally, the S-SCs realize potential applications of steady powering light-emitting diode (LED) lights at 100% strain, smart watch at bending deformation, toy car, and lamp. This work can offer an overwhelming foundation for designing advanced flexible electrodes toward new energy and smart wearable applications. Graphical Abstract
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2023
·
IF 4.3
Chen Yi,Jiang Cailing,Huang Feixiang,Yu Zizhen,Jiang Li
Combining the unique advantages of two-dimensional transition metal carbon/nitrogen compounds (MXene) and the excellent surface-enhanced Raman scattering (SERS) performance of noble metal materials, MXene/Ag NPs films were proposed as nanocarriers for SERS-traceable drug delivery. The films were prepared by two-step self-assembly on positively charged silicon wafers using virtue of the high evaporation of ethyl acetate, the Marangoni effect, and an oil/water/oil three-phase system. With 4-mercaptobenzoic acid (4-MBA) as the probe molecule, the SERS detection limit was 10 −8 M and had shown a good linear relationship in the range of 10 −8 –10 −3 M. Simultaneously, the film had good uniformity, repeatability, and stability. When Ti 3 C 2 T x /Ag NPs films were used as nanocarriers, the anticancer drug doxorubicin (DOX) was loaded onto the surface through 4-MBA, and the tracking and monitoring were realized by SERS. The addition of glutathione (GSH) triggered the thiol exchange reaction, resulting in the shedding of 4-MBA from the surface of the film, which indirectly achieved the efficient release of DOX. Furthermore, the loading of DOX and the drug release effect triggered by GSH maintained a certain stability in serum, which provided a potential possibility for the subsequent loading and release of drugs by films with three-dimensional structures as scaffolds in biological therapy. Graphical abstract
Self-assembled MXene/Ag NPs film nanocarriers for SERS-traceable drug delivery and GSH-triggered high-efficiency drug release
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Nano Research
·
2023
·Vol. 16
·期 7
·10026-10033
·
IF 9.9
Jiang Shihui,Ke Jianxi,Li Guowei,Liu Aijun,Li Xiaohan,Ye Lixiang,Jiang Feilong,Liu Yongsheng,Hong Maochun
Hexagonal-phase NaYF 4 (β-NaYF 4 ) has been acknowledged to be one of the most efficient doping hosts to prepare bright lanthanide-doped luminescent nano-bioprobes for various biomedical applications. However, to date, it remains a great challenge to synthesize ultra-bright lanthanide-doped β-NaYF 4 nano-bioprobes under a low reaction temperature by using conventional synthetic methods. Herein, we first develop an acetic acid (HAc)-mediated coprecipitation method for the preparation of ultra-bright lanthanide-doped β-NaYF 4 nanoprobes under a low reaction temperature at 200 °C. Based on a series of comparative spectroscopic investigations, we show that the use of HAc in the reaction environment can not only promote the rapid α–β phase transformation of NaYF 4 host at 200 °C within 1 h but also boost the absolute photoluminescence quantum yield (PLQY) of NaYF 4 nanocrystals to 30.68% for near-infrared emission and to 3.79% for upconversion luminescence, both of which are amongst the highest values for diverse lanthanide-doped luminescent nanocrystals ever reported. By virtue of their superior near-infrared luminescence, we achieve optical-guided dynamic vasculature imaging in vivo of the whole body at a high spatial resolution (23.8 µm) under 980 nm excitation, indicating its potential for the diagnosis and treatment evaluation of vasculature-related diseases.
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