JOURNAL OF MATERIALS SCIENCE
·
2024
·
IF 3.5
Peng Jingjing,Xu Xiaoling,Zhang Yiying,Chen Yu,Liu Yansheng
Using oxygen vacancies to modify the surface properties of catalysts to enhance catalytic activity, inhibiting reverse reactions can effectively increase synthetic yield. This study presents an M-CeO 2 catalyst derived from MOF-808(Ce), which was successfully applied to the synthesis of dimethyl carbonate (DMC) under dehydration agent-free conditions. Particularly, it has been found that M-CeO 2 catalyst enables the formation of defective microporous structure in ceria catalysts, enriching the surfaces with oxygen vacancy sites, and slowing down the reverse reaction. This leads to the yield of DMC reaching 4.184 mmol/g, corresponding to a significant improvement in the conversion rate of methanol up to 1.42%. Moreover, the M-CeO 2 catalyst exhibited over 1.6 times higher methanol conversion rate than reflux-synthesized ceria nanorods, which can be attributed to their superior CO 2 adsorption and activation capability, as well as the inhibition of reverse reactions. These conclusions are supported by combined surface characterizations and thermodynamic calculations. We developed a novel method for surface engineering of catalysts whose function was combined with dehydrating agents. A possible reaction mechanism for the synthesis of DMC from CO 2 and CH 3 OH on M-CeO 2 was proposed.
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高影响因子
ANALYTICAL SCIENCES
·
2024
·Vol. 40
·期 8
·1437-1448
·
IF 1.8
Feng Chengqi,Chen Zhiyuan,Yin Haoyong,Gong Jianying,Wang Hui,Wu Shengji,Wang Ling
Designing portable electrochemical sensors combined with highly efficient glucose oxidation electrodes offers a significant opportunity for convenient glucose detection. In this report, we present the design and preparation of platinum deposited Ni/NiFe 2 O 4 /Carbon composite (Pt/Ni/NiFe 2 O 4 /C) derived from Ni/Fe metal–organic frameworks (MOFs) followed by Pt deposition. Energy-dispersive X-ray spectroscopy (EDS), X-ray photoelectron spectroscopy (XPS), X-ray diffraction (XRD), and electron microscopy (EM) were utilized to analyze the crystal structure, morphology, and chemical composition of the resulting materials. The glucose sensing capabilities of the optimal Pt/Ni/NiFe 2 O 4 /C-3 were assessed using amperometry methods on a smartphone-based portable device. Acting as a nonenzymatic glucose sensor, the Pt/Ni/NiFe 2 O 4 /C-3 electrode demonstrated notable sensitivity and a low limit of detection for glucose. The portable sensor exhibits high sensitivities of 131.88 μM mM cm −2 at low glucose concentration (3–500 μM) and 29.52 μA mM cm −2 at high glucose concentration (700–4000 μM), achieving a low detection limit of 1.1 μM (S/N = 3). The sensor also demonstrates enhanced selectivity and stability for detecting glucose. Furthermore, the portable sensor exhibits a clear step-ampere response in the detection of serum samples with satisfactory recovery ranging from 99.30 to 101.32%. This suggests the significant potential of portable glucose sensing applications. Graphical abstract
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高影响因子
CELLULOSE
·
2025
·
IF 4.8
Bai Xiaoyu,Zhou Yuan,Li Jiangtao,Xia Zhaoxia,Wang Zhaojiang,Zhang Qiang,Jiang Yuanzhang,Wang Guixin,Tan Lin,Zhang Yong
In this paper, cellulose acetate (CA) and cellulose nanocrystal (CNC) modified polyvinylidene fluoride (PVDF) membranes were prepared by solution blending and non-solvent induced phase separation methods to improve the hydrophilicity and diafiltration capacity of the membranes. The changes in membrane performance before and after modification were systematically studied through simulated dialysis experiments, antifouling performance tests and biocompatibility analysis. The results show that CA blending and CNC doping will change the morphology and structure of the PVDF membrane, improve its hydrophilicity and permeability, and make it show better filtration capacity and antifouling performance. The modified PVDF membrane has higher clearance and diafiltration efficiency for small molecular solutes urea and creatinine, especially for the middle molecular solute lysozyme, while retaining most of the protein molecules, with a flux recovery rate of more than 95%. The modified PVDF membrane also has good biocompatibility. Bio-based CA and CNCs play an important role in improving the antifouling and diafiltration capacity of PVDF membranes.
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ENVIRONMENTAL GEOCHEMISTRY AND HEALTH
·
2024
·Vol. 46
·期 9
·1-20
·
IF 3.2
Yang Yonghao,Luo Zhihao,Wei Zuoan,Zhao Junkang,Lu Ting,Fu Tianbao,Tang Shuang
Tailings dust can negatively affect the surrounding environment and communities because the tailings are vulnerable to wind erosion. In this study, the effects of halides (sodium chloride [NaCl], calcium chloride [CaCl 2 ], and magnesium chloride hexahydrate [MgCl 2 ·6H 2 O]), and polymer materials (polyacrylamide [PAM], polyvinyl alcohol [PVA], and calcium lignosulfonate [LS]) were investigated for the stabilization of tailings for dust control. Erect milkvetch ( Astragalus adsurgens ), ryegrass ( Lolium perenne L.), and Bermuda grass ( Cynodon dactylon ) were planted in the tailings and sprayed with chemical dust suppressants. The growth status of the plants and their effects on the mechanical properties of tailings were also studied. The results show that the weight loss of tailings was stabilized by halides and polymers, and decreased with increasing concentration and spraying amount of the solutions. The penetration resistance of tailings stabilized by halides and polymers increased with increasing concentration and spraying amount of the solutions. Among the halides and polymers tested, the use of CaCl 2 and PAM resulted in the best control of tailings dust, respectively. CaCl 2 solution reduces the adaptability of plants and therefore makes it difficult for grass seeds to germinate normally. PAM solutions are beneficial for the development of herbaceous plants. Among the three herbaceous species, ryegrass exhibited the best degree of development and was more suitable for growth in the tailings. The ryegrass plants planted in the tailings sprayed with PAM grew the best, and the root-soil complex that formed increased the shear strength of the tailings.
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高影响因子
CELLULOSE
·
2024
·
IF 4.9
Guo Yunfeng,Gong Weihua,Zhao Linlin,Yang Yanxiao,Zhou Xiaoqian,Xiao Zefang,Xie Yanjun,Wang Yonggui
In the context of sustainable development, the escalating need for hazardous wastewater treatment underscores the importance of developing innovative cellulose adsorbents for pollutant removal and separation. This study introduces a novel aerogel composed of a vinyl-functional covalent organic framework (COFs) and cellulose nanofibrils synthesized via in situ growth of COFs on aminated cellulose nanofibers (ACNFs). The aerogel’s surface is enriched with active functional groups (hydroxyl, amino, aldehyde, benzene, etc.), enabling diverse physical and chemical interactions with pollutants. Furthermore, a simple post-modification strategy involving thiol-ene click reactions was employed to modify the surface vinyl groups, resulting in two new aerogels (ACNF/COF-COOH and ACNF/COF-SH) to enhance interactions with different aqueous pollutants, specifically by targeting the removal of cationic dyes such as methylene blue (MB) and heavy metals. ACNF/COF-COOH aerogel exhibited a maximum adsorption capacity of 563.0 mg/g for MB, while ACNF/COF-SH aerogel demonstrated high selectivity for heavy metal ion removal, with a mercury ion (Hg 2+ ) distribution coefficient (K d ) of 22,782.0 mL/g. This novel cellulose-based aerogel offers significant potential for removing pollutants from water bodies.
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高影响因子
IONICS
·
2024
·
IF 2.4
Gu Chengyang,Zhang Zhenzhong,zhang Xiaomin,Zhao Fangxia,Chen Haoyi,Tang Xingfeng
In order to determine the optimal crystalline form of manganese-based catalysts for zinc-air battery cathodes, in this paper nano-α-MnO 2 and amorphous manganese dioxide (AMO) materials were successfully synthesised by hydrothermal and liquid-phase co-precipitation methods, respectively. The results show that the spherical AMO material has larger specific surface area and more mesopores than the rod-like α-MnO 2 . Moreover, AMO has abundant structural defects and short-range ordered atomic arrangements that can enhance the ion diffusion kinetics and improve the catalytic performance of the materials. Through electrochemical tests, it is found that the AMO materials have better catalytic properties compared to α-MnO 2 . At a current of 10 mA/cm 2 , its discharge-specific capacity reached 575.2 mAh/g, which is 11.1% higher than that of 517.8 mAh/g for α-MnO 2 . And AMO have higher peak power density and smaller charge/discharge voltage gaps. In the long-cycle test, the initial round-trip efficiency of the electrode prepared of AMO is also better than that of α-MnO 2 . However, when the AMO electrodes are charged and discharged for a long time, part of the AMO will be converted to α-MnO 2 , which lead to a gradual decrease in the cycling stability of the AMO electrodes. Therefore, this paper concludes that AMO materials are superior to α-MnO 2 as catalysts for zinc-air batteries.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2024
·Vol. 22
·期 1
·1-13
·
IF 10.6
Zhang Lifeng,Luo Shihua,Li Wenbin,Su Wanting,Chen Siting,Liu Chunchen,Pan Weilun,Situ Bo,Zheng Lei,Li Ling,Yan Xiaohui,Zhang Ye
Rapid and sensitive nucleic acid detection is vital in disease diagnosis and therapeutic assessment. Herein, we propose a co-freezing localized CRISPR-Cas12a (CL-Cas12a) strategy for sensitive nucleic acid detection. The CL-Cas12a was obtained through a 15-minute co-freezing process, allowing the Cas12a/crRNA complex and hairpin reporter confined on the AuNPs surface with high load efficiency, for rapid sensing of nucleic acid with superior performance to other localized Cas12a strategies. This CL-Cas12a based platform could quantitatively detect targets down to 98 aM in 30 min with excellent specificity. Furthermore, the CL-Cas12a successful applied to detect human papillomavirus infection and human lung cancer-associated single-nucleotide mutations. We also achieved powerful signal amplification for imaging Survivin mRNA in living cells. These findings highlight the potential of CL-Cas12a as an effective tool for nucleic acid diagnostics and disease monitoring.Graphical abstract
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高影响因子
Chemical and Biological Technologies in Agriculture
·
2024
·Vol. 11
·期 1
·1-15
·
IF 5.2
You Yuxin,Wang Chen,Abdallah Yasmine,Liu Quanhong,Liu Chentao,Luo Jinyan,Dai Dejiang,Al-Rejaie Salim S.,Mohany Mohamed,Li Bin,Ogunyemi Solabomi Olaitan,An Qianli
One-pot synthesis of metal nanoparticles under ambient temperature and pressure using reducing and stabilizing materials from microbes is energy-effective and ecofriendly, but upstream extraction of biological raw materials and downstream purification of nanoparticles from bioreactors are laborious and expensive. To simplify the productive process for using metal nanoparticles as microbicides to control plant pathogens, we use an endospore-forming Bacillus biocontrol agent to produce the nano-microbicide and use the bacterial raw materials as bio-microbicides together with the nano-microbicide.Bacillus cells at the stationary phase form endospores and tolerate Ag+ and Ag nanoparticles (AgNPs), while the cell-free culture supernatant (CFCS) mediates the synthesis of AgNPs. AgNPs produced from the Bacillus culture and CFCS show similar physical, chemical, and electrical characteristics, and bactericidal and anti-biofilm activities. Moreover, the diluted products effectively protect the kiwifruit leaves from the infection of the pathogen Pseudomonas syringae pv. actinidiae.This coproduction of bio-microbicide and nano-microbicide is a totally green one-pot synthesis process without extraction and purification and without production of waste and can be easily scaled up using the existing fermentation processing of Bacillus biocontrol agents. The application of the synergistic bio-microbicide and nano-microbicide can effectively control the bacterial canker disease of kiwifruit plants.
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高影响因子
IONICS
·
2024
·
IF 2.4
Mohite Dadaso D.,Chavan Sachin S.,Dubal Sumit,Lokhande P. E.,Kadam Vishal,Jagtap Chaitali,Rednam Udayabhaskar,Ansar Sabah,Kumar Yedluri Anil
The material used for electrodes greatly affects the electrochemical performance of a supercapacitor. This study utilized electrospinning to create ZnO/Polyacrylonitrile (PAN) composite-based nanofibers, which were then heat-treated to form carbon nanofibers (CNFs). The ZnO/PAN-NFs and the resulting ZnO and PAN CNFs were thoroughly characterized for their crystallographic and morphological properties. Electrodes made from ZnO and PAN-based CNFs demonstrated a peak capacitance of 163.44 F g −1 at a scan rate of 10 mV s −1 , which is a 64% increase over electrodes made from PAN CNFs, in addition to enhanced cyclic stability and rate capability. An asymmetric supercapacitor constructed with ZnO/PAN-CNFs//AC showed an energy density of 6.1 Wh kg −1 and a power density of 1000 W kg −1 . The device also exhibited outstanding longevity and electrochemical reversibility, maintaining 84% of its specific capacitance after 5000 cycles. This research seeks to investigate the unique structural and electrochemical properties of the electrospun ZnO/PAN nanocomposite material, contributing to the advancement of high-performance supercapacitor electrodes.
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ACTA PHARMACOLOGICA SINICA
·
2025
·
IF 8.4
Guo Qing,Gan Jun,Wang En-ze,Wei Yu-ming,Xu Jie,Xu Yun,Zhang Fei-fei,Cui Meng,Jia Meng-xing,Kong Ming-jian,Tang Qiong-yao,Zhang Zhe
Patients suffering epilepsy caused by the gain-of-function mutants of the hKCNT1 potassium channels are drug refractory. In this study, we cloned a novel human KCNT1B channel isoform using the brain cDNA library and conducted patch-clamp and molecular docking analyses to characterize the pharmacological properties of the hKCNT1B channel using thirteen drugs. Among cinchona alkaloids, we found that hydroquinine exerted the strongest blocking effect on the hKCNT1B channel, especially the F313L mutant. In addition, we confirmed the antitussive drug tipepidine was also a potent inhibitor of the hKCNT1B channel. Subsequently, we proved that these two drugs produced an excellent therapeutic effect on the epileptic model of KCNT1 Y777H mutant male mice; thus, both could be ready-to-use anti-epileptic drugs. On the other hand, we demonstrated that the activation of the KCNT1 channel by loxapine and clozapine was through interacting with pore domain residues to reverse the run-down of the KCNT1 channel. Taken together, our results provide new insights into the mechanism of the modulators in regulating the KCNT1 channel activity as well as important candidates for clinical tests in the treatment of KCNT1 mutant-associated epilepsy.
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高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·1-16
·
IF 15.7
Peng Wang,Chen Shu,Ma Jingyu,Wei Wenjie,Lin Naixin,Xing Jinchao,Guo Wenjing,Li Heying,Zhang Liang,Chan Kuiming,Yen Andrew,Zhu Guangyu,Yue Jianbo
The interplay between lipid droplets (LDs) and endosomes remains unknown. Here, we screen and synthesize AP1-coumarin, an LD-specific probe, by conjugating a fluorescent dye coumarin to a triazine compound AP1. AP1-coumarin labels all stages of LDs in live cells and markedly induces the accumulation of enlarged RAB5-RAB7 double-positive intermediate endosomes. The AP1-coumarin-labeled LDs contact these intermediate endosomes, with some LDs even being engulfed in them. When LD biogenesis is inhibited, the ability of AP1-coumarin to label LDs is markedly reduced, and the accumulation of enlarged intermediate endosomes is abolished. Moreover, blocking the biogenesis of LDs decreases the number of late endosomes while increasing the number of early endosomes and inhibits the endosomal trafficking of low-density lipoprotein (LDL) and transferrin. Correspondingly, interference with RAB5 or RAB7, either through knockdown or using dominant-negative mutants, inhibits LD catabolism, whereas the expression of a RAB7 constitutively active mutant accelerates LD catabolism. Additionally, CCZ1 knockdown not only induces the accumulation of intermediate endosomes but also inhibits LD catabolism. These results collectively suggest that LDs and endosomes interact and influence each other’s functions, and endosomal trafficking participates in the catabolic process of LDs to maintain lipid homeostasis.
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高影响因子
Scientific Reports
·
2024
·Vol. 14
·期 1
·1-11
·
IF 3.8
Yu Weiwei,Ai Ting,Sun Weizhe,Yang Shuo,Mao Yufeng,Tan JiangLin,Yu Feng,Yin Chen,Jiang Qin,Yu Chengye,Chen Shiling
In this study, MnFe 2 O 4 microspheres were synthesized to activate potassium persulfate complex salt (Oxone) for the degradation of 17β-estradiol (17β-E2) in aqueous solutions. The characteristic of MnFe 2 O 4 was detected by XRD, XPS and SEM-EDS. The experimental results indicated that the degradation of 17β-E2 followed pseudo-first-order kinetics. At 25 °C, 17β-E2 concentration of 0.5 mg/L, MnFe 2 O 4 dosage of 100 mg/L, Oxone dosage of 0.5 mmol/L, and initial pH value of 6.5, the decomposition efficiency of 17β-E2 reached 82.9% after 30 min of reaction. Additionally, free radical quenching experiments and electron paramagnetic resonance analysis demonstrated that SO 4 − • and •OH participated in the reaction process of the whole reaction system, with SO 4 − • being the main reactive oxygen species (ROS). The activation mechanism of the MnFe 2 O 4 /Oxone/17β-E2 system is proposed as follows: MnFe 2 O 4 initially reacts with O 2 and H 2 O in solution to generate active Fe 3+ -OH and Mn 2+ -OH species. Subsequently, Fe 3+ -OH and Mn 2+ -OH react with Oxone in a heterogeneous phase activation process, producing highly reactive free radicals. After four cycles of MnFe 2 O 4 material, the removal rate of 17β-E2 decreased by 24.1%.
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高影响因子
危险品化学品经营许可证（带存储）