Bioactive Materials
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2021
·
IF 14.593
Libin Pang,Renliang Zhao,Jing Chen,Jingxin Ding,Xiaochen Chen,Wenwen Chai,Xu Cui,Xiaolin Li,Deping Wang,Haobo Pan
Critical bone defects caused by extensive excision of malignant bone tumor and the probability of tumor recurrence due to residual tumor cells make malignant bone tumor treatment a major clinical challenge. The present therapeutic strategy concentrates on implanting bone substitutes for defect filling but suffers from failures in both enhancing bone regeneration and inhibiting the growth of tumor cells. Herein, Cu and Mn-doped borosilicate nanoparticles (BSNs) were developed for syncretic bone repairing and anti-tumor treatment, which can enhance bone regeneration through the osteogenic effects of Cu 2+ and Mn 3+ ions and meanwhile induce tumor cells apoptosis through the hydroxyl radicals produced by the Fenton-like reactions of Cu 2+ and Mn 3+ ions. In vitro study showed that both osteogenic differentiation of BMSCs and angiogenesis of endothelial cells were promoted by BSNs, and consistently the critical bone defects of rats were efficiently repaired by BSNs through in vivo evaluation. Meanwhile, BSNs could generate hydroxyl radicals through Fenton-like reactions in the simulated tumor microenvironment, promote the generation of intracellular reactive oxygen species, and eventually induce tumor cell apoptosis. Besides, subcutaneous tumors of mice were effectively inhibited by BSNs without causing toxic side effects to normal tissues and organs. Altogether, Cu and Mn-doped BSNs developed in this work performed dual functions of enhancing osteogenesis and angiogenesis for bone regeneration, and inhibiting tumor growth for chemodynamic therapy, thus holding a great potential for syncretic bone repairing and anti-tumor therapy.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2021
·
IF 5.816
Jiaxian Liu,Guyang Ning,Kun Shi,Man Zheng,Yuena Sun,Yongjun Gao,Yufan Zhang,Huan Wang
In this work, a string of different proportion trimetallic loaded the N-doped hollow porous carbon nanospheres (N-HPCS@Co Cu Fe NSs) were successfully crafted by a simple and economical method. Herein, the hollow-carbon structure was formed by etching carbon nanospheres. Moreover, owing to the presence of the PDA and P123, high dispersed nano spheres with mesopores were obtained. By this way, the catalyst can expose unique internal cavity and short transport path. Meanwhile, trimetal-based metal-organic frameworks (MOFs) Co Cu Fe alloy nano spheres (Co Cu Fe NSs) are first prepared. Creatively, PDA acts as the carbon resource, nitrogen resource and metal grafting agent simultaneously. Through a series of tests, N-HPCS@Co 1 Cu 1 Fe NSs has the best electrocatalytic performance and durable stability. This work highlights the current advances of hollow porous carbon structure, trimetallic active sites and N-doping, as well as, endow high electrocatalytic activity and durability for HER and OER .
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CHEMICAL ENGINEERING JOURNAL
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2021
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IF 13.273
Sihan Li,Yanqi Gan,Syed Jalil Shah,Ruimeng Wang,Wenxue Gong,Rule Wei,Hongbing Ji,Zhongxing Zhao,Zhenxia Zhao
Competitive adsorption of complex nonsteroidal anti-inflammatory drugs (NSAIDs) from wastewater often reduces the adsorption capacity of object pollutants on most porous materials. To address this issue, NSAIDs molecules were proposed for engineering imprinted pores in UiO-66s to boost their adsorption capacity towards diclofenac sodium (DCF) and Cu(II) in a complex solution. Naproxen (NAP) with proper chemical structure was proved to introduce more imprinted pores (at ~19 Å) with enhanced mesoporous volume, abundant unsaturated metal sites, and terminal hydroxyl groups in UiO-66@NAP. These new intriguing properties awarded high adsorption affinity to UiO-66@NAP for DCF and Cu(II), and their adsorption capacities reached up to 385 and 52 mg/g for single DCF and Cu(II) components, respectively. When DCF and Cu(II) simultaneously appeared in an aqueous solution, DCF was proved to preferentially occupy adsorption sites on UiO-66@NAP with higher adsorption kinetics compared to Cu(II). Afterwards, these pre-adsorbed DCF acted as new adsorption sites to bridge more Cu(II) in the solution. Similarly, the adsorbed Cu(II) on UiO-66@NAP had the same reciprocal bridging effect towards DCF, which realized the synergistic adsorption of DCF and Cu(II) over UiO-66@NAP. Notably, DCF was found to greatly boost the synergistic effect of the Cu(II) adsorption. As a result, UiO-66@NAP exhibited 1.5 and 2.6 times higher uptakes for DCF (573 mg/g) and Cu(II) (135 mg/g) in the binary system compared to their single pollutant system, and its equilibrium adsorption capacity was much higher compared to several state-of-the-art adsorbents. The current work set out a new strategy to modify MOFs for enhanced adsorption of complex NSAID contaminants and revealed a deep understanding of the interactions between NSAIDs and heavy metals ions .
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CHINESE JOURNAL OF CHEMICAL ENGINEERING
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2021
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IF 3.171
Xin Yong,Hong Chen,Huawang Zhao,Miao Wei,Yingnan Zhao,Yongdan Li
The effects of SO 2 on an one-pot synthesized Cu-SSZ-13 catalyst for selective reduction of NO x by NH 3 were examined. The addition of SO 2 inhibited NO x conversion significantly below 300 °C, while no effect on NO x conversion was observed above 300 °C. TGA, TPD , and XPS results showed that the deactivation was caused by the formation of (NH 4 ) 2 SO 4 , SO 2 chemisorption on the isolated Cu 2+ ion sites, as well as the formation of CuSO 4 -like species. Among them, the site-blocking effect of (NH 4 ) 2 SO 4 on Cu 2+ was the primary reason for deactivation. Fortunately, 89% of deNO x activity of the poisoned catalyst was recovered after thermal treatment at 500 °C in air, where (NH 4 ) 2 SO 4 was completely decomposed. The activity was further recovered with regeneration temperature increasing to 600 °C, removing the adsorbed SO 2 on the Cu 2+ sites. The regeneration at 600 °C could not recover the activity completely, because of the high stability of CuSO 4 -like species.
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Scientific Reports
·
2021
·Vol. 11
·期 1
·1-13
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IF 4.38
Tang Xi,Zhang Yifei,Li Weiqi,Geng Jinju,Ren Hongqiang,Xu Ke
Humic acid (HA) is the main component of organic matter in effluent from wastewater treatment. The effective removal of HA is significant. In this study, a novel catalyst was prepared using a transition metal oxide as the active component and Al 2 O 3 as a granular carrier. The mechanism of catalytic ozonation of HA under neutral pH conditions and its efficiency were investigated. Under the chosen conditions (an ozone concentration of 2.2 mg/L, 50 mg/L HA solution, catalyst dosage of 5 g/L and initial pH of 6.49), the Cu/Ce–Al 2 O 3 bimetallic catalyst led to 54.79% TOC removal rate after 30 min; the removal rate by ozone alone was only 20.49%. The characteristics of organic compounds determined by FT-IR and GC–MS showed that organic compounds were degraded significantly by the catalytic treatment. The addition of catalysts could effectively degrade toxic intermediates and reduce the acute toxicity produced by ozonation. Humic acid substances were largely removed and transformed into biodegradable intermediates. This study proposes a new and efficient ozonation catalyst for practical applications in advanced wastewater treatment.
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RSC Advances
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2021
·Vol. 11
·期 37
·22780-22788
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IF 3.361
Xiaoyi Sun,Qingjie Liu,Shuai Liu,Xintang Zhang,Shanshan Liu
A series of MOx–Cr2O3–La2O3/TiO2–N (M = Cu, Fe, Ce) catalysts with nitrogen doping were prepared via the impregnation method. Comparing the low-temperature NH3-SCR activity of the catalysts, CeCrLa/Ti–N (xCeO2–yCr2O3–zLa2O3/TiO2–N) exhibited the best catalytic performance (NO conversion approaching 100% at 220–460 °C). The physico-chemical properties of the catalysts were characterized by XRD, BET, SEM, XPS, H2-TPR, NH3-TPD and in situ DRIFTS. From the XRD and SEM results, N doping affects the crystalline growth of anatase TiO2 and MOx (M = Cu, Fe, Ce, Cr, La) which were well dispersed over the support. Moreover, the doping of N promotes the increase of the Cr6+/Cr ratio and Ce3+/Ce ratio, and the surface chemical adsorption oxygen content, which suggested the improvement of the redox properties of the catalyst. And the surface acid content of the catalyst increased with the doping of N, which is related to CeCrLa/TiO2–N having the best catalytic activity at high temperature. Therefore, the CeCrLa/TiO2–N catalyst exhibited the best NH3-SCR performance and the redox performance of the catalysts is the main factor affecting their activity. Furthermore, in situ DRIFTS analysis indicates that Lewis-acid sites are the main adsorption sites for ammonia onto CeCrLa/TiO2–N and the catalyst mainly follows the L–H mechanism.
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MICROCHEMICAL JOURNAL
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2020
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IF 3.594
Hui Ma,Ronghua Zhang,Qi Kang,Tao Wang,Jianhong Xiao,Xuezhi Li,Li Yu
A facile, low-cost and label-free liquid crystals (LCs) sensing platform laden with Cu(ClO 4 ) 2 was herein established for detection and distinction of sulfhydryl amino acids, namely cysteine (Cys) and homocysteine (Hcy). When introducing Cys or Hcy to the fluid interface with Cu(ClO 4 ) 2 , the optical appearance of LCs exhibited a bright-to-dark transition, which coupled to the interactions between Cu 2+ and the sulphydryl of amino acids. Concomitantly with, the orientation of LCs varied from tilted to homeotropic state. Besides, this sensor system did not respond to other nineteen amino acids that make up human proteins. The detection limit of Cys and Hcy is around 0.01 mg/mL (~82.5 μM) and 0.05 mg/mL (~370.0 μM), respectively. Compared with Cys, the as-prepared LCs sensing platform shows a higher detection limit and longer response time for Hcy, based on which these two sulfhydryl amino acids can be distinguished from each other. This can be attributed to the additional methylene for Hcy, resulting in formation of a five-membered ring Hcy thiolactone which may not chelate with Cu 2+ . The LCs-based analytical platform constructed in this work can provide a convenient and label-free method for detecting and differentiating sulfhydryl amino acids.
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INTERNATIONAL JOURNAL OF ENERGY RESEARCH
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2020
·Vol. 45
·期 2
·2058-2069
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IF 3.741
Junkai Gao,Xi Tang,Yan Chen,Yi Liu
Summary The thermal conductivity of shape-stabilized phase change material of polyethylene glycols/porous carbon microspheresdoping withcopper particles (PEG/CARM-Cu) was enhanced based on the adsorption and in situ reduction of Cu 2+ using polydopamine microsphere (PDAM)material as the adsorbent. The synthesis of PDAM has the merits of simplicity and environmental friendliness, and the in situ reduction of Cu 2+ through pyrolysis has the advantages of easy operation and cost effectiveness. Copper particles prepared by in situ reduction were tightly fixed on the surface of the support ofporous carbon microsphere (CARM), which avoided the sedimentation of copper particles during the phase change process of PEG/CARM-Cu. According to the SEM, TEM, XRD, TGA and DSC test results, PEG/CARM-Cu possessed favorable thermal reliability and stability, and the phase change enthalpy of PEG/CARM-Cu-2 could reach 101.50 J/g. Additionally, the thermal conductivity of PEG/CARM-Cu-2 (0.497 W/(m·K)) was enhanced by 93.3% compared to that ofpure PEG (0.257 W/(m·K)). Therefore, the PEG/CARM-Cu developed in this paper possessed great potential for real applications.
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Environmental Science-Water Research & Technology
·
2020
·Vol. 7
·期 3
·479-486
·
IF 3.449
Zhiwei Yang,Xiaonan Tan,Daojian Tang,Jing Li,Jiahai Ma
In this study, the contrasting activities and pathways of Mn2+/Cu2+–HCO3− systems for Congo red (CR) dye degradation are presented. The Mn2+–HCO3− system (with the well-known MnIVO as the reactive species) did not degrade CR, while the Cu2+–HCO3− system (with high-valent Cu proposed as the reactive species) had a good oxidizing ability for CR. Further, HO radicals in the classic Fenton-like system made no contribution to CR degradation with both Cu and Fe ions as catalysts. The results indicate that reactive species in metal–HCO3− AOPs need prudent examination and better understanding of the underlying mechanism would benefit the development of more efficient AOPs.
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CATALYSIS LETTERS
·
2020
·Vol. 150
·期 8
·2437-2445
·
IF 2.482
Yang Zhi,Luo Mingsheng,Liu Qinglong,Shi Buchang
A potassium- and copper-modified iron-based catalyst (K–Cu–Fe/SiO 2 ) was synthesized by the co-precipitated method. The general structural properties of the catalyst were characterized with various techniques, including SEM, XRD, H 2 -TPR, N 2 adsorption–desorption and Raman spectroscopy. The results reveal that the fresh catalyst is mainly composed of α-Fe 2 O 3 phase with rod-shaped morphology formed by nanoparticles. The effect of activation process on the Fischer–Tropsch synthesis catalytic performance was then investigated. It shows that activation process has an important influence on the reactive stability. The in situ XRD and in situ Raman spectroscopy were used to study the structural changes of the Fe-based catalyst during reduction and reaction processes. The Fe 2 C iron carbide as the main active phase was observed after reduction process. Graphic Abstract
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SCIENCE OF THE TOTAL ENVIRONMENT
·
2020
·
IF 6.551
Liping Cao,Ze-Wen Kang,Qi Ding,Xiaohui Zhang,Hetong Lin,Mengshi Lin,Da-Peng Yang
Bioremediation is one of efficient methods to solve the issues of water or soil contaminated by metal ions . However, the harvested biowaste is often troublesome to handle owing to the second pollution. Herein, the waste eggshell membrane was used to adsorb Cu 2+ in wastewater, which was then converted into biochar containing copper ions (Cu 2+ -Cu + /Biochar) via a rapid pyrolysis . By integrating the collective advantages of eggshell membrane and Cu 2+ -Cu + , such as superior electrical conductivity, enlarged electrochemically active surface area, unique three-dimensional porous network characteristics, and fast charge transport, the Cu 2+ -Cu + /Biochar system can be used as a self-supporting sensor for detection of nitrite (NO 2 − ). The sensor demonstrated superior electrochemical sensing abilities accompanied by a broad linear range (1–300 μM), ultralow detection limit (0.63 μM), and high sensitivity (30.0 μA·mM −1 ·cm −2 ). In addition, the fabricated electrochemical sensor has excellent stability, good reproducibility, and strong anti-interference performance. More importantly, the sensor has a high recovery rate when it is used to detect nitrite in tap water , mineral water , and sausage, indicating the feasibility of using this sensor in practical applications. This study provides a green and sustainable approach for simultaneous treatment of biomass waste eggshell membrane, remedy of heavy metals, and electrochemical detection of nitrite.
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Catalysis Science & Technology
·
2020
·Vol. 10
·期 8
·2343-2352
·
IF 5.721
Ziheng Zhen,Wenxiang Tang,Wei (Willy) Chu,Tao Zhang,Li Lv,Shengwei Tang
The dispersity and the neighboring degree of different sites play crucial roles in the catalytic performance of dual site catalysts. The solution of precursors was encapsulated into microdroplets by forming a microemulsion. The average diameter of microdroplets was about 45 nm. This guaranteed that the dosage of precursors was at the attogram level and only about a thousand precursor molecules were encapsulated in each microdroplet. An anti-solvent extraction method was applied to extract water from the microdroplets with acetonitrile. The precursors co-precipitated in the microdroplets due to the loss of water. The encapsulated precursors in the microdroplets co-precipitated together in nanoscale space, so the neighboring degree of the two precursors was improved significantly. The prepared catalyst was characterized by ICP-OES, BET, XRD, H2-TPR, TEM and XPS. Compared with the Cu–ZnO/Al2O3 (CZA) catalysts prepared by the conventional impregnation method, the CZA catalysts prepared by the proposed strategy had much stronger interaction and a better neighboring degree of the dual active sites. They also showed very good catalytic performance for the reverse water gas shift (RWGS) reaction. The CO2 conversion of the designed CZA catalysts was about 1–2 times higher than that of the CZA catalysts prepared by the conventional impregnation method at 0.1 MPa, 300–400 °C and a CO2/H2 mole ratio of 1.
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