SOLID STATE SCIENCES
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2019
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IF 2.155
Yunfei Li,Fei Liang,Huimin Song,Wang Liu,Zheshuai Lin,Guochun Zhang,Yicheng Wu
A new pyrophosphate crystal, CsLiMgP 2 O 7 , was successfully synthesized using the high-temperature solution method. It crystallizes in the orthorhombic system with space group Pnma (No. 62). CsLiMgP 2 O 7 features a [LiMgP 4 O 18 ] 6-membered ring fundamental building block composed of four PO 4 and two Li/MgO 4 tetrahedrons, which connected with each other to form an interesting 6-membered ring chain. The DSC analysis proves that CsLiMgP 2 O 7 melts congruently. The spectral analyses were performed on the title compound, and the relationship between the electronic structures and optical properties has also been investigated by theoretical calculations.
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Nanoscale
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2019
·Vol. 11
·期 19
·9444-9456
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IF 6.97
Xinyi Lian,Zhou Chen,Xiang Yu,Tingting Fan,Yunyun Dong,Hesheng Zhai,Weiping Fang,Xiaodong Yi
To solve the intrinsic deficiency inherited from the large band gap of ZnSn(OH)6 (ZSH), a gradual sulfur doping strategy is first proposed here to expand the optical absorption range, improve the separation efficiency of photogenerated electron–hole pairs, and thus enhance the photocatalytic activity. It is demonstrated that the distribution of sulfur in the flower-like ZSH (the sulfur doped sample is denoted as S-ZSH) tends to be largest on the outer most surface and becomes smaller towards the interior. The S-ZSH therefore has a gradual bandgap structure that is beneficial for transferring photogenerated charge carriers from the interior to the surface, which will greatly enhance the utilization of photoelectrons. As a result, the visible light photocurrent density of S-ZSH and the photocatalytic degradation rate of rhodamine (RhB) are about 5 and 10 times higher than with pristine ZSH, respectively.
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JOURNAL OF MEMBRANE SCIENCE
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2018
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IF 6.578
Shun Ren,Dongqing Liu,Yingbo Chen,Shulin An,Yiping Zhao,Yufeng Zhang
Membranes of anion channels in matrix were constructed through amphiphilic self-assembly of polyelectrolyte , SO 3 H group containing polyamide 6 (SPA6). SPA6 molecules self-aggregated into 255 nm micelles with negative charges at the surface in casting solution. Micelles switched into nanofibers , which formed pompoms of divergent arrangement of nanofibers from the center after immersed in coagulation bath. They adhered and piled up to construct the membrane. Charged groups were remained at the surface of pompoms during solidification. The gaps between spheres provided channels full of anions, which supplied great repulsion to anions. It endowed membranes the potential to remove anion dyes from aqueous solution. The rejection was up to 99.73% for 500 mg/L Congo red and 85.68% for 100 mg/L Acid blue 93 and 63.06% for 100 mg/L Methyl orange after first filtration. Total removal percentage was 95.48% for Acid blue 93 and 79.51% for Methyl orange after second filtration. Self-aggregation of dye molecules also helped their high removal efficiency. Flux of film 30 M of 100 mg/L CR solution dropped to 67.34% and rejection rate was higher than 95% in 1500 min. Flux could be brought back to more than 90% of the original values after washed by deionized water , suggesting that 30 M had good anti-fouling capacity. SPA6 membranes displayed a potential for effective treatment of textile wastewater.
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CHINESE JOURNAL OF CHEMICAL ENGINEERING
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2018
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IF 1.712
Chongwen Jiang,Jundong Zhu,Bing Wang,Lu Li,Hong Zhong
Zirconium doped mesoporous KIT-6 samples with different Si/Zr ratios were synthesized by the direct hydrothermal method. Various characterization techniques confirm that highly distributed ZrO 2 nanoparticles and multi-coordinated Zr 4+ species are incorporated in the mesoporous composites. One-pot synthesis of 5-hydroxymethylfurfura(HMF) from glucose was examined in the presence of Zr-KIT-6(20) the molar ratio of Si to Zr is 20 under aqueous system. The effects of temperature, reaction time, catalyst dosage and biphasic solvent system on the conversion of glucose and the HMF yield were investigated. It was found that the glucose conversion and the HMF yield have been improved from 54.8% to 79.0% and from 19.5% to 34.5% in the biphasic MIBK-water system, respectively. Both the acidity of Zr-KIT-6(20) and the biphasic MIBK-water system are responsible for the improved performance of glucose dehydration to HMF.
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ACS Applied Materials & Interfaces
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2018
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IF 8.097
Youdan Zheng,Rui Wang,Xiangyu Dong,Lixin Wu,Xu Zhang
The rapidly growing fields of aerospace, energy, and electronic devices raise the demand for materials with ever-increasing mechanical properties and electrical and thermal conductivity. However, the combination of unusual high performance is difficult to attain. In this study, using prebuilt three-dimensional (3D) closely packed interconnected multiwalled carbon nanotube (MWNT) networks as a backbone for assembly of polymer matrix, a novel, green (solvent-free), and energy-saving method to prepare robust, highly electrical, and thermal conductive polyamide nanocomposites is reported. The as-prepared nanocomposites exhibit significant enhancements of 16 orders of magnitude in electrical conductivity and 505% in thermal conductivity, which mainly benefits from the contributions of closely packed 3D networks and conductive pathways of carbon nanotubes. In addition, even at a high MWNT loading of 25 wt %, the as-prepared nanocomposites still possess a high tensile strength of 99.4 MPa and Young’s modulus of 5.3 GPa. The performance of the as-prepared nanocomposites exceeds that of most of the composites, which confirms the potential of the prebuilt MWNT network method for fabricating robust and highly conductive nanocomposites and the importance of good interconnectivity of nanofillers–nanofillers and nanofillers–matrix. The special fabrication method could open up a broad range of possibilities for aerospace, conducting elements, and structural nanomaterials, as well as electronic components with the requirements of heat dissipation, mechanical strength, thermal repair, corrosion resistance, and so on.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2018
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IF 2.829
Yanjun Liu,Ping Na,Jitao Chen,Yulong Xie
K 2 Zn 3 [Fe(CN) 6 ] 2 @ Ni-P (KNiP) composites with high cesium selectivity were synthesized for the first time. Nickel phosphorus (NiP) was used as a solid base for the adsorption of K 2 Zn 3 [Fe(CN) 6 ] 2 (KZnHCF). The synthesized KNiP composites were characterized by SEM, TEM, XRD , VSM and BET. The characteristic results demonstrated that the composites possess a ball-shape structure, a large surface area of 305.031 m 2 /g and high saturation magnetization of 2.95 emu/g. The ICP-OES analyser was used to determine the concentration of ions in this study. KNiP showed good cesium adsorption performance over a wide pH range and high selectivity for cesium over coexistent competing ions. Analysis of dynamics showed that KNiP has good adsorption performance toward cesium, with an adsorption capacity of 54.95 mg/g. Equilibrium was achieved within only two hours and the experimental data fit the Pseudo second-order model, indicating that the adsorption process was chemisorption . The adsorption process followed the Freundlich isotherm model, indicating that it mainly occured on a heterogeneous surface.
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INTERNATIONAL JOURNAL OF PHARMACEUTICS
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2017
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IF 3.649
Qilong Wang,Qiuyu Wei,Qiuxuan Yang,Xia Cao,Qiang Li,Feng Shi,Shan Shan Tong,Chunlai Feng,Qingtong Yu,Jiangnan Yu,Ximing Xu
[6]-Gingerol, one of the components of the rhizome of Ginger, has a variety of biological activities such as anticoagulant, antioxidative, antitumor, anti-inflammatory, antihypertensive, and so forth. However, as one of the homologous phenolic ketones, [6]-gingerol is insoluble in water which limits its applications. Herein, we prepared [6]-gingerol proliposomes through modified thin-film dispersion method, which was spherical or oval, and physicochemically stable with narrow size distribution. Surprisingly, in vitro release of [6]-gingerol loaded proliposome compared with the free [6]-gingerol was significantly higher and its oral bioavailability increased 5-fold in vivo. Intriguingly, its antitumor effect was enhanced in the liposome formulation. Thus, our prepared [6]-gingerol proliposome proved to be a novel formulation for [6]-gingerol, which significantly improved its antitumor effect.
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Marine Drugs
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2017
·Vol. 15
·期 9
·284
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IF 3.503
Wenbo Dong,Weiping Li,Yu Chen,Yanchun Ye,Shaohua Jin
In the present work, a fluorescent H2O2biosensor was constructed by encapsulating fluorescent probe Rhodamine B (RhmB) in the hydrophobic cavity of the cyclodextrin (β-CD) and immobilizing catalase (CAT) on the 2-NH2of chitosan (CTS) in a chitosan 6-OH immobilized β-cyclodextrin derivative (CTS-6-CD). The inclusion complex of CTS-6-CD to RhmB (CTS-6-CD-RhmB) was prepared by a solution method. Its structure and inclusion efficiency were determined by Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), and fluorescence spectroscopy (FL). CAT was immobilized on CTS-6-CD-RhmB to eventually form the functional membrane, CTS-6-CD-RhmB-CAT, via glutaraldehyde crosslinking, which was further characterized by FTIR and FL, and used as a H2O2biosensor. The functional membrane was used to simultaneously oxidize and detect H2O2. The detection condition was optimized as pH 8, a reaction temperature of 25 °C, and an immobilized enzyme concentration of 2 × 10−4mol/L. The fluorescence response of the biosensor exhibited a good linear relationship with the concentration of H2O2in the range of 20 mΜ–300 μM and the detection limit of 10−8mol/L.Keywords:chitosan;catalase;β-cyclodextrin;Rhodamine B;fluorescent biosensor
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Frontiers in Bioengineering and Biotechnology
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2023
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IF 5.7
Wang Cai,Xin Dongyuan,Yue Qianwen,Wan Huiyu,Li Qian,Wang Ying,Wu Jingguo
Introduction: Interleukin-6 (IL-6) is a multifunctional polypeptide cytokine composed of two glycoprotein chains, which plays an important role in many cellular reactions, pathological processes, diagnosis and treatment of diseases and so on. The detection of IL-6 plays a promising role in the cognition of clinical diseases.Methods: 4-mercaptobenzoic acid (4-MBA) was immobilized on the gold nanoparticles modified platinum carbon (PC) electrode with the linker IL-6 antibody, and finally formed an electrochemical sensor that specifically recognized IL-6. Through the highly specific antigen-antibody reaction, the IL-6 concentration of the samples to be detected. The performance of the sensor was studied by cyclic voltammetry (CV) and differential pulse voltammetry (DPV).Results: The experimental results showed that the linear detection range of the sensor for IL-6 was 100 pg/mL–700 pg/mL and the detection limit was 3 pg/mL. In addition, the sensor had the advantages of high specificity, high sensitivity, high stability and reproducibility under the interference environment of bovine serum albumin (BSA), glutathione (GSH), glycine (Gly) and neuron specific enolase (NSE), which provided a prospect for specific antigen detection sensor.Discussion: The prepared electrochemical sensor successfully detected the content of IL-6 in standard and biological samples, showing excellent detection performance. No significant difference was found between the detection results of the sensor and that of ELISA. The sensor showed a very broad prospect in the application and detection of clinical samples.
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JOURNAL OF ENVIRONMENTAL MANAGEMENT
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2022
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IF 8.91
Guangyu Duan,Zhanfang Cao,Hong Zhong,Xin Ma,Shuai Wang
Heavy metal wastewater pollution has become an ecological challenge worldwide. This study reports the development of a novel poly (6-acryloylamino-N-hydroxyhexanamide) (PAHHA) resin for effective adsorption of heavy metal ions , including Cu 2+ , Pb 2+ and Ni 2+ . The chelating resin was synthesized by the grafting reaction between 6-amino-N-hydroxyhexanamide and polyacrylic resin , thus containing the hydroxamate and acylamino groups. The batch adsorption experiments revealed that the PAHHA resin exhibited an excellent adsorption performance for Cu 2+ , Pb 2+ and Ni 2+ . The maximum adsorption capacities of Cu 2+ , Pb 2+ and Ni 2+ were determined to be 238.59, 232.48 and 115.77 mg·g −1 , respectively. Based on the adsorption kinetics , the pseudo-second-order kinetic model was noted to fit well for all metal ions. The metal ion concentration as a function of the equilibrium adsorption capacity fitted well with the Langmuir isotherm , thus indicating the single layer adsorption process . The adsorption mechanism was investigated by using Fourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM), density functional theory (DFT) calculations, X-ray photoelectron spectroscopy (XPS) and adsorption isotherms . It was revealed that the PAHHA resin possessed multiple active sites, including –CONHOH, –CONH– and –COOH, which could strongly adsorb the metal ions. Specifically, the –CONHOH group displayed a high affinity by forming a stable five-membered ring with heavy metal ions. Overall, the developed resin exhibits advantages such as simple synthesis, inexpensive raw material and good recyclability , along with high adsorption ability, thus providing a new approach for efficiently treating wastewater contaminated with heavy metal ions.
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POLYMER DEGRADATION AND STABILITY
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2022
·
IF 5.204
Wentao He,Huahui Xu,Pingan Song,Yushu Xiang,Shuhao Qin
Flame-retardant functionalized nanomaterials have attracted much research interests due to the combined advantages of organic and inorganic components. In the present study, P, N-decorated halloysite nanotube (MA-PPA@HNT) was prepared via simple steps of phenphosphinic acid intercalation and subsequent electrostatic interaction with melamine. Compared to unmodified HNT, the incorporation of MA-PPA@HNT into polyamide 6 (PA6)/aluminum diethylphosphinic acid (AlPi) composite results in significant improvement of flame retardancy. At equal HNT loading of 2wt%, the UL-94 rating grade of PA6/AlPi/MA-PPA@HNT composite was V-0, whereas that of PA6/AlPi/HNT composite V-2. And compared with PA6 , there is a decrease of peak heat release rate (pHRR) and total heat release (THR) by 72.6% and 17.4%, respectively. The flame retardant mechanism was analyzed by cone calorimetry, gas volatility and characterization of char residues. It is considered that MA-PPA@HNT plays the critical role of promoting the formation of P, Si-rich intumescent char in the condensed phase and enhancing the barrier effect for heat and mass transfer.
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Frontiers in Pharmacology
·
2022
·
IF 5.988
Sun Chao-Yue,Talukder Milton,Cao Di,Chen Cun-Wu
Abemaciclib is a cyclin-dependent kinases 4/6 (CDK4/6) inhibitor approved for the treatment of metastatic breast cancer. Preclinical studies suggest that abemaciclib has the potential for lung cancer treatment. However, several clinical trials demonstrate that monotherapy with abemaciclib has no obvious superiority than erlotinib to treat lung cancer patients, limiting its therapeutic options for lung cancer treatment. Here, we show that the US Food and Drug Administration (FDA)-approved drug, gilteritinib, enhances the cytotoxicity of abemaciclib through inducing apoptosis and senescence in lung cancer cells. Interestingly, abemaciclib in combination with gilteritinib leads to excessive accumulation of vacuoles in lung cancer cells. Mechanistically, combined abemaciclib and gilteritinib induces complete inactivation of AKT and retinoblastoma (Rb) pathways in lung cancer cells. In addition, RNA-sequencing data demonstrate that combination of abemaciclib and gilteritinib treatment induces G2 phase cell-cycle arrest, inhibits DNA replication, and leads to reduction in homologous recombination associated gene expressions. Of note, abemaciclib-resistant lung cancer cells are more sensitive to gilteritinib treatment. In a mouse xenograft model, combined abemaciclib and gilteritinib is more effective than either drug alone in suppressing tumor growth and appears to be well tolerated. Together, our findings support the combination of abemaciclib with gilteritinib as an effective strategy for the treatment of lung cancer, suggesting further evaluation of their efficacy is needed in a clinical trial.
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