ACS Sustainable Chemistry & Engineering
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2019
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IF 6.97
Guanyi Lin,Shan Jiang,Chunying Zhu,Taotao Fu,Youguang Ma
The mass-transfer process of CO2 absorption into aqueous solution of N-methyldiethanolamine (MDEA) + diethanolamine (DEA) in a T-shaped microchannel was studied using a high-speed camera. The effects of two-phase flow rates and diethanolamine concentration on CO2 absorption efficiency, liquid mass-transfer coefficient kL, specific surface area a, and volumetric mass-transfer coefficient kLa were investigated under slug flow. Results showed that the CO2 absorption efficiency increased with the increase of DEA concentration and liquid flow rate, and decreased with increasing gas flow rate. The kL increased with the increase of liquid flow rate and DEA concentration, while it was insensitive to gas flow rate. For a given liquid flow rate, both kLa and a increased rapidly with gas flow rate and then the trend was slowing down. The increase of liquid flow rate and DEA concentration led to the decrease of the a, whereas the kLa was improved. The enhancement of the liquid flow rate on kL and kLa was more obvious under low DEA concentration. An empirical correlation for predicting the volumetric mass-transfer coefficients kLa was proposed by taking the Hatta number Ha into account for characterizing the effect of chemical reaction.
研究领域:
化学工程
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传质过程
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碳捕集与封存（CCS）
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微流控技术
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反应工程
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高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
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2020
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IF 2.369
Lijiang Guo,Hongxia Li
The solubility of the RbCl–CsCl–H2O ternary system has been investigated at the temperature range from 298.15 to 348.15 K by two different methods, namely, the Flow-Cloud-Point (FCP) method and the Isothermal Dissolve Equilibrium (IDE) method. The measured solubility for this ternary system at 298.15 K by FCP method is consistent with the reported result in literature. The measured solubility results for this ternary system at 323.15 K by the FCP and IDE, two different methods that are consistent with each other, which indicated the results are more reliable. Meanwhile, the measured liquid–wet solid–solid lines proved that the equilibrium solid phases are two types of solid solutions (Rb,Cs)Cl(ss) and (Cs,Rb)Cl(ss) rather than pure salts (RbCl and CsCl) reported in literature. For the first time, the solubility of the RbCl–CsCl–H2O ternary system at 308.15 and 348.15 K has been measured by IDE method. The measured results shown that the equilibrated solid phases in this ternary system at 308.15 and 348.15 K are two types of solid solution (Rb,Cs)Cl(ss) and (Cs,Rb)Cl(ss), at RbCl rich side and CsCl rich side, respectively.
研究领域:
无机化学
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溶液热力学
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物理化学
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Journal of Physical Chemistry C
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2020
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IF 4.189
Yashuai Pang,Yang Zhang,Haiwu Zheng,Qiongzhe Yu,Xu Chen,Jihuai Wu,Qiwei Jiang
To enable the ZnO photoanode obtain superior photovoltaic performance, here, we design a T-ZnOw/ZnONP double-layer structure composite photoanode, in which tetra-needle-like zinc oxide whiskers (T-ZnOw) are used as the light scattering layer, the needles of T-ZnOw inserted into the ZnO nanoparticles (ZnONP) layer form a unique ZnO needle array structure, which acts as one-dimensional (1-D) low resistance channels and enables photoelectrons to reach the fluorine-doped tin oxide (FTO) conductive layer through relatively small number of interfaces. These characteristics make this double-layer structure photoanode possess lower photoelectron transport resistance and lower photoelectron recombination probability, resulting in higher photovoltaic efficiency compared with the traditional single-layer ZnONP photoanode. Moreover, the proposed self-adsorption and self-insertion preparation method of the T-ZnOw layer offer a novel strategy to form 1-D array structures.
研究领域:
材料科学
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光伏技术
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纳米材料
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能源工程
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Advanced Healthcare Materials
·
2022
·Vol. 11
·期 22
·2201166
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IF 11.092
Yueyang Deng,Caixia Tan,Shuguang Huang,Honghao Sun,Zhaoting Li,Jing Li,Zhanwei Zhou,Minjie Sun
Tumor metastasis contributes to high cancer mortality. Tumor cells in lymph nodes (LNs) are difficult to eliminate but underlie uncontrollable systemic metastasis. The CC chemokine receptor 7 (CCR7) is overexpressed in tumor cells and interacts with CC chemokine ligand 21 (CCL21) secreted from LNs, potentiating their lymphatic migration. Here, a site-specific polyplex is developed to block the CCR7-CCL21 signal and kill tumor cells toward LNs, greatly limiting their lymphatic infiltration. A CCR7-targeting small interfering RNA (siCCR7) is condensed by mPEG-poly-(lysine) with chlorin e6 (Ce6) modification (PPLC) to form PPLC/siCCR7. The knockdown of CCR7 by siCCR7 in tumor cells significantly reduced their response on CCL21 and LN tropism. Additionally, photodynamic therapy-mediated immune activation precisely targets and kills tumor cells released from the primary foci before they reaches the LNs, reducing the number of tumor cells entering the LNs. Consequently, the PPLC/siCCR7 polyplexes inhibited up to 92% of lung metastasis in 4T1 tumor bearing mice and reduced tumor cell migration to LNs by up to 80%. This site-specific strategy optimized anti-metastasis efficacy and promotes the clinical translational development of anti-metastatic therapy.
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产品关联
DOI
PubMed
高影响因子
FUEL
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2022
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IF 8.035
Zhe Bai,Luyao Wang,Hongwei Cao,Xiangwen Zhang,Guozhu Li
Hydrodesulfurization (HDS) is an effective way to reduce sulfur content in oil for the enforcement of more stringent environmental regulations. MoS 2 has been widely used as an effective component for catalyzing HDS, and needs to be extensively studied in depth. Herein, MoS 2 nanoflowers with the symbiosis of 1T-2H phases in the basal planes and coexistence of S and Mo vacancies are prepared via the assembly of many nanosheets by a one-pot solvothermal method. The morphology, crystal phase structure and defects of these 1T-2H MoS 2 samples were well characterized. The 1T/2H ratio and the state of vacancies were effectively tuned by changing the solvothermal conditions. Active and stable 1T-2H mixed MoS 2 nanoflowers with high content of 1T phase and moderate S and Mo vacancies were obtained by the regulation of oxalic acid in the mixture of ethanol and water. In the HDS of dibenzothiophene at 300 °C and 4 MPa, the optimal catalyst of MoS 2 -water–ethanol-OA exhibited a substrate conversion of 89.3% in 10 h. Moreover, the activity of MoS 2 -water–ethanol-OA was well retained without any decrease in the recycling experiment.
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Journal of Immunotoxicology
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2022
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IF 3.439
Wenhua Zhong,Penghuan Chang,Lianfang Gan,Lifan Zhong,Zhaoxin Yang
Most current methods to assess T-cell-dependent antibody responses (TDAR) are semi-quantitative and based on measures of antibody titer generated against a standard antigen like keyhole limpet hemocyanin (KLH). The precision, sensitivity, and convenience of TDAR assays might be improved by applying rapid, sensitive, specific cytometric bead assays (CBA). In the study here, KLH antigen was covalently coupled onto the surface of cytometric beads using immune microsphere technology, and IgM antibody capture spheres were prepared for use in pretreatment processing of samples. The working parameters associated with this novel TDAR-CBA system were optimized in orthogonal experiments. The optimal concentration of the KLH coating solution in this system was 160 μg/ml, that of the anti-KLH IgG capture spheres 6.0 × 105/ml, and the optimal dilution of fluorescein isothiocyanate (FITC)-conjugated Affini-Pure Goat Anti-Mouse IgG (H + L) was 60 μg/ml. Repeated tests indicated that this approach yielded good linearity (r2 = 0.9937) method, with a within-run precision of 3.1–4.9%, and a between-run precision of 4.4–4.9%. This new approach had a limit of detection of 113.43 ng/ml (linear range = 390.63–50 000), and an interference rate of just 0.04–3.51%. Based on these findings, it seems that a new mouse TDAR assay based on CBA can be developed that would appear to be more sensitive, accurate, and precise than the current TDAR assay approaches based on traditional ELISA.
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DOI
PubMed
高影响因子
FOOD CHEMISTRY
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2022
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IF 9.231
Xueying Chen,Changyong Cai,Zhijian Tan
T -butanol is widely used in three-phase partitioning (TPP). This study used deep eutectic solvents (DESs) to substitute t -butanol for tomato peroxidase (POD) purification. DES-5 (menthol and octanoic acid) was screened as the optimal solvent. The extraction process was optimized using single-factor experiments. Thereafter, the major three factors were optimized by response surface methodology (RSM). When the ammonium sulfate ((NH 4 ) 2 SO 4 ) concentration was 42%, DES: crude extract (v/v) was 2:1, pH was 5.7, and extraction temperature was 30 °C, the recovery and purification fold reached a maximum of 104.71% and 9.76, respectively. The obtained tomato POD was analyzed by sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE), which showed that this system could effectively purify POD. Finally, recycling studies indicated the good cycle stability of the DES. This TPP based on DESs is greener and more efficient, indicating that DESs can be good alternative solvents for further applications of TPP.
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DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
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IF 7.312
Tongtong Ren,Suli Liu,Hong Li,Angui Zhang,Xingang Li,Wei Yuan,Xin Gao
Utilization of F-T synthetic to produce value-added C 8 linear α-olefin is a promising alternative approach, however, the purification of α-olefin from F-T synthetic products is a great challenge, especially for removing 2-methyl-1-heptene (MH). This article addresses the novel method of etherification reaction to remove MH from F-T synthetic products, and develop by far the most efficiency reactive distillation (RD) method to intensified the etherification process. The scarcity of thermodynamic data was measured and regressed by the activity coefficient models, furthermore, kinetics of the etherification reaction of MH with methanol was explored using an ion exchange resin as catalyst, and then fitted by a pseudo-homogeneous model. The pilot-scale RD experimental results show that the conversion of MH reaches 91.83 % and the purity of α-olefin increases by 14.9 wt% (percentage points). Process analysis method was used to realize the optimization of design and operating parameters of etherification RD column based on the developed rigorous model. The optimization results show that the conversion of MH achieves 99.74 % and the purity of α-olefin achieves 96.87 wt%, which is also illustrated that the novel method for removing MH is proposed paving the way for purification of α-olefin from F-T synthetic products.
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JOURNAL OF MOLECULAR LIQUIDS
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2021
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IF 6.165
Zilong Cui,Zhiruo Zhao,Liang Yao,Yonghong Hu
Brassinolide is a new environmental protection plant growth regulator. With the aim of knocking down selfcost and scale up agriculture market-place emulation, come what will manufacture method is adopted, the final step crystallization is significant for getting exclusive substances. The purpose of this study is to provide some authentic and general energetics data for the actual industrial production of brassinolide. In the research, the solid–liquid equilibrium of brassinolide in twelve pure solvents (tetrahydrofuran, dimethyl sulfoxide, ethanol, acetone, methanol, trichloromethane, acetonitrile, 1-butanol, isopropanol, xylenes, n-hexane and n-heptane) and three binary solvent mixtures (trichloromethane + tetrahydrofuran, acetonitrile + tetrahydrofuran and n-hexane + tetrahydrofuran) were tested by the circumstance of atmosphere pressure at range temperatures between 278.15 K and 323.15 K. Four models like the Buchowski–Ksiazaczak λh model, the modified Apelblat model, the Jouyban-Acree-van't-Hoff model and the Redich-Kister (CNIBS/R-K) model were employed to describe the change trend of solubility. On the groundwork of a series of data analysis, tetrahydrofuran is a better organic solvent and n-hexane can be applied as an effective anti-solvent when separating out brassinolides. These solubility data are very important for optimizing the extraction process and recrystallization of brassinolide.
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JOURNAL OF CHEMICAL THERMODYNAMICS
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2021
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IF 3.178
Shuo Cheng,Yu Bao,Yue Cui,Jingtao Wang
In this paper, the solubility and dissolution thermodynamic properties of dodecanedioic acid (DDDA) in four binary-mixed solvents (ethyl acetate + ethanol, ethyl acetate + acetic acid, and ethyl acetate + acetone) were investigated. The gravimetric method was employed to determine the mole fraction solubility of DDDA in different solvent ratios from 288.15 K to 328.15 K under the atmosphere. In the binary solvents of ethyl acetate + ethanol and ethyl acetate + acetic acid, when the composition was varied the solubility change was not monotonous, and the phenomenon of co-solvency occured. Furthermore, four models were employed to fit the solubility data, among which the modified Apelblat equation and CNIBS/R-K model had better fitting results. Finally, the dissolution thermodynamic properties of DDDA were analyzed based on the modified Van’t Hoff equation.
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POLYMER DEGRADATION AND STABILITY
·
2021
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IF 5.03
Zsófia Kovács,Ákos Pomázi,Andrea Toldy
The complexity of recycling crosslinked polymer composites has promoted the use of thermoplastic in situ polymerisable matrices, including ε-caprolactam-based polyamide 6 (PA6) in long-fibre reinforced composites. Their uptake by the automotive industry has created a need for adequate flame retardancy, which poses several challenges: flame retardants may hinder the in situ polymerisation reaction; moreover, the fibre reinforcement can filter out the additives not soluble in ε-caprolactam during liquid moulding composite processing, such as thermoplastic resin transfer moulding (T-RTM). We discussed the feasibility of the flame retardancy of ε-caprolactam-based PA6 and its composites, including the solubility of the additives in ε-caprolactam and their effect on the polymerisation reaction and fire performance. We evaluated the correlations between the flame retardant structure and the inhibition of polymerisation. Finally, we briefly summarised the composite processing and coating technologies suitable for preparing flame retarded ε-caprolactam-based PA6 matrix and composite systems, as well as the most often used tests for their characterisation.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2021
·
IF 7.312
Liwei Yang,Xuyang Hao,Dian Yu,Peng Zhou,Yaqi Peng,Yanyan Jia,Chuanliang Zhao,Jiaojie He,Chuanlang Zhan,Bo Lai
Due to the low concentrations of pharmaceuticals and personal care products (PPCPs), traditional water treatment processes are difficult to degrade them effectively. 2,5-bis (tributylstannyl) thiophene-perylene diimide-T@TiO 2 (Bis-PDI-T@TiO 2 ) composite photocatalyst is firstly prepared by the bisolvent phase transfer method and has a good ability to activate persulfate (PS) under visible light. 5 ppm Carbamazepine (CBZ) (a typical PPCPs) can be completely degraded by 1.0 g/L prepared photocatalyst and 1.0 mM PS within 30 min in the 0.1 wt% Bis-PDI-T@TiO 2 (PT 0.1 ) system under visible light. Four species of reactive oxidizing species were identified for CBZ degradation, including sulfate radical (SO 4 •− ), hydroxyl radical ( • OH), superoxide radical (O 2 •− ), and positive hole (h + ), and all contributed to CBZ degradation. Furthermore, the PT 0.1 photocatalyst exhibits the high stability and recyclability. This study also proposed the reaction mechanism of the Vis/PS/Bis-PDI-T@TiO 2 system and constructed a route of carbamazepine degradation in the coupled system.
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