Scientific Reports
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2019
·Vol. 9
·期 1
·1-13
·
IF 4.011
Chen Cuihua,Chen Jiali,Shi Jingjing,Chen Shuyu,Zhao Hui,Yan Ying,Jiang Yucui,Gu Ling,Chen Feiyan,Liu Xunhong
In this study, a fingerprint-activity relationship between chemical fingerprints and hepatoprotective activity was established to evaluate the quality of salt-treated Apocyni Veneti Folium (AVF). Characteristic fingerprints of AVF samples exposed to different concentrations of salt were generated by ultrafast liquid chromatography tandem triple time-of-flight mass/mass spectrometry (UFLC-Triple TOF-MS/MS), and a similarity analysis was performed based on common characteristic peaks by hierarchical clustering analysis (HCA). Then, the hepatoprotective activity of AVF against CCl 4 -induced acute liver damage in mice was investigated by assessing biochemical markers and histopathology, which showed that a high dose of AVF exposed to low levels of salt stress produced a marked amelioration of hepatic damage compared with the other salt-treated AVF. Finally, fingerprint-activity relationship modeling, which was capable of discovering the bioactive markers used in the quality evaluation, was investigated by the chemical fingerprints and the hepatoprotective activities utilizing multivariate statistical analysis, gray correlation analysis (GCA) and bivariate correlation analysis (BCA). The results showed that the accumulation of polyphenols, such as flavonoids and phenolic acids, in AVF subjected to low levels of salt stress could result in the effective scavenging of free radicals. Therefore, the present study may provide a powerful strategy to holistically evaluate the quality of salt-treated AVF in combination with chemical fingerprint and bioactivity evaluation.
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PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2019
·Vol. 30
·期 24
·21219-21228
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IF 2.195
Zhao Yan,Chen Yuan,Liu Qingqing,Yuan Ming,Huang Yunpeng,Lian Jiabiao,Bao Jian,Qiu Jingxia,Xu Hui,Xu Yuanguo,Li Huaming
Cobaltous oxide/nickel–iron oxide (Co 3 O 4 /NiFe 2 O 4 ) hybrids were fabricated via a template-free hydrothermal route with cyclodextrin as a reactor and a further two-step annealing treatment in an air atmosphere. The hybrid is composed of many small nanoparticles with a particle size distribution range from 20 to 50 nm. The hybrid combined the advantages of Co 3 O 4 and NiFe 2 O 4 nanoparticles, presenting enhanced electrochemical properties than its single component. The Co 3 O 4 /NiFe 2 O 4 (0.6:1) hybrid electrode exhibited the highest specific capacitance and great electrochemical cycle stability (over 90.7% of total capacitance at 2 A g −1 after 1000 cycles and still kept 84.6% at 5 A g −1 after 5000 cycles). This may be ascribed to the common contribution of each component, which not only provided good electronic conductivity for efficient charge transfer but also a stable structure for better ions diffusion. A Co 3 O 4 /NiFe 2 O 4 //AC asymmetry supercapacitor was assembled and manifested the highest energy density of 76.0 Wh kg −1 at a power density of 859.7 W kg −1 and still kept 37.3 Wh kg −1 at the highest power density of 6.0 kW kg −1 . This work indicated that the Co 3 O 4 /NiFe 2 O 4 hybrid should be a potential active material for the electrochemical application.
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INTERNATIONAL JOURNAL OF LEGAL MEDICINE
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2019
·Vol. 134
·期 1
·177-183
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IF 2.094
Xie Mingkun,Song Feng,Li Jienan,Xie Bowen,Wang Shuangshuang,Wang Weizhi,Ma Hong,Luo Haibo
Genotyping by targeting short tandem repeats (STRs) has been widely used in forensic applications. However, most commercial kits detect autosomal STRs or Y-STRs alone, which waste both time and opportunity. The AGCU Expressmarker 16 + 22Y Kit includes 16 autosomal and 22 Y-chromosomal STR loci and is designed for the forensic science field and obtaining quicker results. Here, we conducted the validation study according to Scientific Working Group on DNA Analysis Methods (SWGDAM) guidelines. Validation of PCR-based studies, species specificity, sensitivity, DNA mixture studies, inhibitors, precision, and sizing accuracy were performed. Furthermore, this system was also tested in 346 random male samples from Han, Hui, Tibetan, and Zhuang populations in China, showing its high power for forensic discrimination in the Chinese population. In addition, this system was able to deal with AMELY deletion cases, which can correctly identify sex in forensic criminal investigations. Our results suggested that the AGCU Expressmarker 16 + 22Y Kit is a useful tool for rapid criminal investigation.
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PubMed
高影响因子
Journal of the Australian Ceramic Society
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2019
·Vol. 56
·期 3
·895-903
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IF 0.692
Ma Jing-Yi,Zhang Yi-Bing,Wang Jun-Xia,Song Yu-Yang,Zhou Tong,Wang Yan,Wang Hao-Yu,Wang Jin
In the present paper, the ordered Nd 2 Zr 2 O 7 pyrochlore was primarily synthesized by flux method and the MgO-Nd 2 Zr 2 O 7 composite ceramics were fabricated subsequently through a conventional sintering route. A suite of characterization techniques, including XRD, Raman and BSE-EDS were employed to investigate the phase composition and microstructure of the as-prepared Nd 2 Zr 2 O 7 and MgO-Nd 2 Zr 2 O 7 samples. The acid solubility of the MgO-Nd 2 Zr 2 O 7 composite ceramics was also tested. XRD results showed that the ordered Nd 2 Zr 2 O 7 pyrochlore can be synthesized when the calcination temperature is in the range of 850–1200 °C. Raman results suggested that the chemical bonds of Nd 2 Zr 2 O 7 pyrochlore get stronger, and more ordered structure can be gradually formed with the increase of calcining temperature. For the MgO-Nd 2 Zr 2 O 7 composite ceramics, XRD results also showed that the Nd 2 Zr 2 O 7 phase in the composite ceramics presents higher crystallinity degree and no other phase is formed after sintering at 1400–1550 °C. Moreover, BSE-EDS results indicated that the MgO-Nd 2 Zr 2 O 7 composite ceramics are compact and dense, and the MgO and Nd 2 Zr 2 O 7 phases are almost uniformly distributed between each other. In addition, the relative density of the bulk ceramics was about 96–98%, and it was concluded that ≥ 1500 °C could be the suitable sintering temperature to produce MgO-Nd 2 Zr 2 O 7 composite ceramics. At last, the dissolution behavior of the ceramics in nitric acid solution revealed that only MgO in the MgO-Nd 2 Zr 2 O 7 composite ceramics can be dissolved in the 11 M HNO 3 solution within 24 h, and the dissolution rate was relatively low because of the high densification of the sample.
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CHINESE JOURNAL OF POLYMER SCIENCE
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2019
·Vol. 38
·期 1
·9-16
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IF 2.804
Man Shou-Kuo,Wang Xiao,Zheng Jin-Wen,An Ze-Sheng
Polymerization-induced self-assembly (PISA) is an efficient and versatile method to afford polymeric nano-objects with polymorphic morphologies. Compared to dispersion PISA syntheses based on soluble monomers, the vast majority of emulsion PISA formulations using insoluble monomers leads to kinetically-trapped spheres. Herein, we present aqueous emulsion PISA formulations generating worms and vesicles besides spheres. Two monomers with different butyl groups, n -butyl ( n BHMA) and tert -butyl ( t BHMA) α -hydroxymethyl acrylate, and thus possessing different water solubilities were synthesized via Baylis-Hillman reaction. Photoinitiated aqueous emulsion polymerizations of n BHMA and t BHMA employing poly(ethylene glycol) macromolecular chain transfer agents (macro-CTAs, PEG 45 -CTA, and PEG 113 -CTA) at 40 °C were systematically investigated to evaluate the effect of monomer structure and solubility on the morphology of the generated block copolymer nano-objects. Higher order morphologies including worms and vesicles were readily accessed for t BHMA, which has a higher water solubility than that of n BHMA. This study proves that plasticization of the core-forming block by water plays a key role in enhancing chain mobility required for morphological transition in emulsion PISA.
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IONICS
·
2019
·Vol. 26
·期 2
·777-787
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IF 2.289
Jing Pengcheng,Lu Huimin,Yang Wenwen,Cao Yuan,Xu Binbin,Cai Wei,Deng Yan
Magnesium batteries based on Mg 2+ /Li + dual ion electrolytes (MLIBs) have attracted increasing attention due to fast Li + or Mg 2+ /Li + insertion kinetics, abundant Mg resources, and high volumetric capacity of dendrite-free Mg anodes. Herein, we report polyaniline (PANI)–coated VS 4 @reduced graphene oxide (rGO) with nanostructures synthesized via hydrothermal synthesis and subsequent PANI polymerization as the cathode material for MLIBs. The PANI layer serves as a conductive medium to enhance electron transfer and Mg 2+ /Li + transportation as well as to mitigate the structure changes of VS 4 during the cycling process. Indeed, this material demonstrates enhanced electrochemical performance with a high discharge capacity of 200.7 mAh g −1 after 20 cycles and 91.2% retention after 50 cycles. Mechanism analysis reveals that Li + insertion into VS 4 produced an amorphous VS 4 host in the first discharge, which inclined to store Mg 2+ rather than Li + in the subsequent cycles. Our study provides new insights into the development of amorphous electrode materials for magnesium batteries.
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高影响因子
CHINESE JOURNAL OF POLYMER SCIENCE
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2019
·Vol. 38
·期 1
·72-83
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IF 2.804
Han Yue,Tang Dong-Hao,Wang Guang-Xing,Sun Ya-Nan,Guo Ying,Zhou Heng,Qiu Wen-Feng,Zhao Tong
Vanillin was used as sustainable source for phthalonitrile monomer synthesis, and allyl/propargyl ether moieties were introduced to improve the processability at the minimal cost of thermal properties. The synthesis route was optimized to minimize side-reactions and simplify post-processing, and the monomers were obtained in high purity and good yields. The curing behavior, mechanism, and processability of the monomers were studied, and the thermal properties of cured polymers were evaluated. Of the two monomers, the allyl ether-containing one exhibited a wide processing window of 185 °C, and was mainly cured into phthalocyanine and linear aliphatic structures through self-catalytic curing process. Also, the glass transition temperature was higher than 500 °C. In contrast, the propargyl ether-containing monomer could only be partially cured, and heat resistance was found to be compromised. Compared with traditional petroleum-based phthalonitrile resins, the bio-based monomers could be cured without the addition of catalysts, and improvement in processability was achieved at no cost of thermal performances.
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CELLULOSE
·
2019
·Vol. 26
·期 17
·9335-9348
·
IF 3.917
Yang Yingying,Huang Wei,Guo Zengpei,Zhang Shiyu,Wu Feng,Huang Jingjing,Yang Hongjun,Zhou Yingshan,Xu Weilin,Gu Shaojin
Abstract Superhydrophobic cotton fabrics with improved ultraviolet resistance were prepared via in situ growing NH 2 -MIL-125(Ti)(Ti-MOF) nanoparticles on cotton fibers and subsequently coating with polydimethylsiloxane (PDMS) under room temperature. The synergetic effect of Ti-MOFs nanoparticles and PDMS was critical and essential for obtaining a superhydrophobic coating with anti-UV property. The surface microstructure, chemical composition, and superhydrophobic property of the as-prepared fabrics were characterized by K/S value, scanning electron microscopy, X-ray photoelectron spectroscopy, energy dispersive spectroscopy, and water contact angle (WCA) measurements. The as-prepared cotton fabrics not merely exhibited desirable superhydrophobic property with a water contact angle (WCA) of 154.7 ± 0.7° and a sliding angle of 3.6°, but also displayed the considerable UV resistance. The oil–water separation, stability of UV protection and superhydrophobicity were also investigated. The superhydrophobicity, anti-ultraviolet property, and K/S value of as-prepared PDMS/Ti-MOFs@cotton fabrics were stable after 300 cycles of abrasion and 5 cycles of washing. The facile synthesis technique provided a simple method for scalable construction of multifunctional fabrics. Graphic abstract
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高影响因子
CELLULOSE
·
2019
·Vol. 26
·期 17
·9323-9333
·
IF 3.917
Zhou Jing,Hu XinYue,Zhu YiYuan,Lyu HongFen,Zhang Lei,Fu FeiYa,Liu XiangDong
This work proposes a facile approach to improve the durability of antibacterial cotton fabric by using carboxymethyl chitosan (CMC) and l -methionine (Met) as a combination binder to immobilize silver nanoparticles (Ag NPs). The durable antibacterial function is achieved by grafting CMC and Met molecules onto a cotton fabric by a simple pad-dry-cure process, followed by the preparation of Ag NPs on the modified surface. This surface modification process provides the cotton fabric with an excellent antibacterial effect and outstanding laundering durability. Structural analyses of the modified surface revealed that the covalent bonds between Met, CMC, and cotton fibers were formed, and the thioether groups caused the stable immobilization of the Ag NPs. Notably, the modification process does not significantly damage the original fiber structure. The desired cotton properties such as vapor permeability, water absorptivity, and flexibility of the modified fabric were very close to the original cotton. Moreover, the safety to human skin was verified by cytotoxicity tests using fibroblast cells.
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高影响因子
FIBERS AND POLYMERS
·
2019
·Vol. 20
·期 8
·1577-1585
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IF 1.439
Wan Yizao,Lin Zhonghong,Gan Deqiang,Cui Teng,Wan Meirong,Yao Fanglian,Zhang Quanchao,Luo Honglin
Graphene-based nanomaterials have been used as biomaterials to enhance cell adhesion, growth, and differentiation. However, the effect of graphene materials on cancer cell behavior has not been thoroughly investigated. Herein, we have incorporated graphene oxide (GO) into cellulose acetate (CA) to develop nanofibrous scaffolds for in vitro cancer cell culture, which is a crucial step for drug screening and cancer research. The Go/CA scaffolds were seeded with breast cancer cells and cell viability, proliferation, adhesion, infiltration, and morphology were assessed. Mechanical characterization demonstrated that the mechanical properties of GO/CA scaffolds were significantly better than bare CA scaffold and improved with increasing GO content. More importantly, the in vitro cell studies showed that the cancer cells on GO/CA scaffolds had significantly higher viability and better cell adhesion and growth than bare CA. Our results confirm an important role of GO in improving mechanical properties and cancer cell performance on GO/CA scaffolds. These results suggest the potential of the GO/CA scaffolds as a promising candidate for in vitro cancer models.
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高影响因子
MACROMOLECULAR RESEARCH
·
2019
·Vol. 28
·期 1
·51-56
·
IF 1.758
Zhang Siyu,Shi Baoli,Yang Guang
Due to the high toxicity for brain and the nervous system of humans and other living organisms, the design and fabrication of a robust and sensitive method for the detection of Pb 2+ in the aqueous solution has attracted the increasing attention among scientists. Herein, a colorimetric and fluorometric sensor for the detection of Pb 2+ in the aqueous solution by incorporating a new phenylboronic acid functionalized polydiacetylene liposome was designed. The molar ratio of 4:1 between the monomers, 10,12-pentacosadiynoic acid (PCDA) and phenylboronic acid functionalized PCDA (PCDA-pBA) not only offered sufficient binding sites for Pb 2+ , but also interrupted the efficient π -conjugation backbone of polydiacetylene (PDA) chains associated with the color and fluorescence changes. Compared with other metal ions, only Pb 2+ could cause the color change and the fluorescence enhancement. Moreover, the hybrid PDA liposomes exhibited high sensitivity, fast response time (10 s), and a reasonable detection limit for Pb 2+ (0.1 µM). This work not only provides a versatile methodology for the fabrication of sensors for Pb 2+ detection, but also is of great fundamental value for a deeper understanding of the complexion-induced color changes based on polydiacetylene materials, and may pave the way for fabrication a new method for recognizing other metal ions.
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CHEMICAL PAPERS
·
2019
·Vol. 74
·期 3
·971-984
·
IF 1.246
Gong Qiuyan,Guo Zidong,Sun Zhihao,Gong Jinggeng,Wei Fengyu
Abstract Ginkgo biloba leaves (GBL) contain many biologically active compounds such as flavonoids and terpene trilactones. In this study, graphene oxide (GO)-assisted ethanol reflux extraction (GERE) was adopted to extract the Ginkgo flavonoids (GF) from GBL, and the kinetics and mechanism of GF extraction were studied. SEM, XRD and FT-IR results all showed that GO could disrupt the cellulose structure and reduce the crystallinity of GBL. Through the obtained experimental data, it can be seen that So–Macdonald model was suitable to describe the extraction kinetics with high values of the coefficient of determination ( R 2 ≥ 0.994) and low values of the residual sum of squares ( RSS ≤ 0.00022). The optimum leaching conditions of GERE were 70% (v/v) of ethanol concentration, 16 mL/g of liquid to solid ratio, 1.5 mg/g of GO dosage and 140 rpm of stirring speed at 70°C for 4 h by the single factor experiments. Under these conditions, the equilibrium yield of GF by GERE reached 82.63%, about 5.60% higher than the conventional ethanol reflux extraction (ERE). The value of the apparent activation energy obtained was 3.69 kJ/mol for GERE, 6.35% lower than that for ERE at a temperature within the range of 40–70 °C. HPLC results indicated that GO could not decompose flavonoids. The higher yield of GF can be attributed to the catalytic hydrolysis to the cell wall by GO, which can decrease the apparent activation energy and accelerate the leaching of GF at the fast diffusion stage. Graphic abstract GERE method is an efficient and green extraction technology and So–Macdonald model satisfactorily described the extraction kinetics of Ginkgo flavonoids.
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