INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2025
·
IF 8.5
Zhiyue Feng,Shiqi Chen,Ke Han,Qiang Ma,Boyan Sun,Chujun Liu,Qiqi Wang,Hao Zhao,Zimo Liu,Junying He,Zhimeng Zhang,Haiyang Jiang
Infections caused by multidrug-resistant bacteria significantly hinder wound healing, highlighting the need for non-antibiotic alternatives. Here, we developed a multifunctional hydrogel platform, LAMC@PCN-224@BBR, by incorporating photodynamic PCN-224 and the natural product berberine (BBR) into lipoic acid-modified chitosan (LAMC). This design combines photo-crosslinking for enhanced tissue adhesion with photodynamic therapy (PDT) for antimicrobial activity. Upon light irradiation, the hydrogel generates reactive oxygen species (ROS), effectively eradicating methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli ( E. coli ) with an efficiency exceeding 99 %. Its excellent biocompatibility and adaptive adhesion allow conformal coverage of irregular wounds. In a full-thickness skin defect model, the hydrogel accelerated healing by suppressing inflammation, promoting collagen deposition, enhancing angiogenesis, and polarizing macrophages toward the pro-regenerative M2 phenotype. These findings demonstrate that the LAMC@PCN-224@BBR hydrogel is a promising clinical strategy for controlling resistant infections and promoting tissue regeneration.
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高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2025
·
IF 8
Ying Zhang,Cheng Qin,Jiajia Pang,Xiaoxue Pan,Rehab Khaled Mahmoud,Xiaosheng Tang,Zunyao Wang,Ruijuan Qu
This study systematically investigated the degradation of bisphenol AF (BPAF) using a visible light-assisted magnetite/persulfate (Vis/magnetite/PS) system. Visible light irradiation significantly enhanced the activation efficiency of PS by magnetite, leading to improved BPAF removal. Under the optimal conditions, a removal efficiency of 91.7 % was achieved. Notably, while magnetite exhibited specificity toward PS activation, the system also demonstrated exceptional versatility by achieving 99 % degradation efficiency for methylene blue. Monochromatic light irradiation revealed wavelength-dependent degradation kinetics, with BPAF removal efficiencies following the order as: Vis > purple > red > blue > green > yellow light. Significant elevation in superoxide radical and singlet oxygen contribution rates occurred when transitioning from standard irradiation to monochromatic light or darkness. Four primary transformation pathways of BPAF were identified: hydroxylation, sulfate addition, bond cleavage, and coupling reactions. Photocoupling was found to selectively increase the abundance of hydroxylated and coupled products. The system reduced operational costs compared to zero-valent iron-based systems, owing to the utilization of natural sunlight and unprocessed magnetite ore. These findings provide fundamental insights into the wavelength-dependent synergism between light and magnetite in PS activation, offering a scalable and eco-friendly strategy for water and wastewater remediation.
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高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Juanru Huang,Zhenhua Hu,Yanrui Xue,Yao Wang,Yu Wang,Fanyong Yan
In heterogeneous catalysis, optimizing the separation of photogenerated carriers by tuning synthesis of catalysis, is always a crucial strategy to strengthen the photocatalytic performance. Here, O vs -BiOCl@Carbon dots/Bi 2 WO 6 (OB/CB) of a Z-scheme heterojunction, was fabricated by coupling O vs -BiOCl (OB) nanosheets with carbon dots/Bi 2 WO 6 (CB) compound in one-pot hydrothermal treatment. The optimized heterojunction of OB/CB with the weight ratio of 1:2 (OB/CB-1:2) achieve the degradation efficiency of 91.66 % of Tetracycline (TCH) under the visible light, which was much higher than those of pure OB of 34.46 % and CB of 81.92 %. Meanwhile, the Z-Scheme OB/CB-1:2 also display the extremely adaptable and effective to eliminate Rhodamine B (Rh. B) of 99.43 %, Oxytetracycline (OTC) of 83.04 % and Ciprofloxacin (CIP) of 87.66 %, respectively. The photocatalytic activities are probably attributed to the recombination of photogenerated carriers, occurring at the accumulated electrons (e - ) from the conduction band (CB) of Bi 2 WO 6 (BWO) transfer to the holes (h + ) from the valence band (VB) of O vs -BiOCl in the heterojunction driven by CDs, and thus the more oxidizing h + of BWO with the more reducing e - can be retained synchronously. The extra oxygen vacancies maximize the reduction ability of e - and further support the higher photocatalytic activity of OB/CB-1:2 than other counterparts. In addition, the corresponding photoelectrochemical measurements and scavenging experiments cooperatively demonstrated that the formation of OB/CB-1:2 definitely facilitated the separation of photogenerated carriers, and further revealed that species of •O 2 ‾ and h + mainly contributed to the photodegradation. This work illustrated that the potential utilization of CDs can effectively modulate Z-scheme heterojunction to achieve water remediation etc.
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Small
·
2025
·
IF 12.1
Zhijun Liu,Zhiying Guo,Ruoyan Liu,Zhirui Liu,Lanlan Zhai,Qian Miao,He Huang,Yun Yang,Jun Zou,Chao Zou
Quantum-confined perovskite nanoplatelets (NPLs) with ultra-narrow emission linewidths represent promising blue-emission materials for ultrahigh-definition displays. However, their practical applications have been severely hindered by material instability and poor charge transport properties. Herein, we employed thioglycolic acid (TA) and anilinium bromide (AnHBr) as dual short-chain ligands, successfully synthesizing monodisperse CsPbBr 3 NPLs with an emission peak at 463 nm and a remarkable photoluminescence quantum yield (PLQY) of 89%. This approach involves introducing TA into the perovskite precursor solution, where its carboxyl groups strongly coordinate with uncoordinated Pb 2+ on the surface to form TA-modified NPLs (TA-NPLs). Subsequently, the introduced Br − from AnHBr effectively fills existing Br − vacancies on initial NPLs’ surface to form TA- and AnHBr-modified NPLs (TA+AnHBr-NPLs). Both ligands enhance structural stability through strong interactions with the [PbBr 6 ] 4− octahedra. The resulting solution maintains stable blue emission when stored in air for 21 days and exhibits excellent photostability. The fabricated TA+AnHBr-NPLs-based light-emitting diodes demonstrate efficient deep-blue electroluminescence at 461 nm, with an external quantum efficiency (EQE) of 1.00%, CIE color coordinates of (0.146, 0.085), and remarkable spectral stability. This study offers a method for synthesizing high-stability perovskite materials and further fabricating high-performance devices.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Min Cai,Zhaoshuang Li,Rongkang Chen,Yin He,Xu Xu,Xu-Min Cai,Wei Yuanfeng,Zhenfei Yang,Chuntao Kuang,Guoen Yang,Yan Qing,Xingong Li,Yiqiang Wu
Room-temperature phosphorescent (RTP) materials based on carbon dots (CDs) have received much attention due to their potential applications in anti-counterfeiting in recent years. However, it remains a considerable challenge to prepare CDs-based RTP materials with sunlight excitation and excellent stability. This work provides a straightforward method for one-step calcination of rosin-based carbon quantum dots (R-CDs) with aluminum hydroxide (Al(OH) 3 ) to create ecologically sustainable room-temperature phosphorescent materials (CDs@Al 2 O 3 ). CDs@Al 2 O 3 exhibit excitation dependence, emitting green phosphorescence under 365 nm excitation, yellow phosphorescence under visible light excitation, and blue-green phosphorescence under sunlight excitation. Surprisingly, CDs@Al 2 O 3 display time-dependent afterglow, switching from blue to green phosphorescence when excited at 285 nm. Furthermore, after being submerged in polar and acid-base solutions for 21 days, the phosphorescence of CDs@Al 2 O 3 is still visible to the unaided eye. At last, CDs@Al 2 O 3 composites are utilized in applications including smart flashing traffic signals, multi-level information, and anti-counterfeiting. This work expands creative application opportunities by offering a straightforward and adaptable approach to generating ecologically friendly RTP materials.
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Materials Today Bio
·
2025
·
IF 10.2
Shaobo Zhai,Jiaqian You,Zheng Yang,Yang Liu,Tianming He,Yuchuan Wu,Xuyan Wei,Mucong Li,Xiaolu Shi,Fengxiang Gao,Shunli Chu
Wound infection is a serious clinical challenge, often accompanied by persistent inflammatory response and the threat of increased bacterial resistance, there is an urgent requirement to develop a wound dressing with potent antimicrobial as well as immunomodulatory effects. In this study, we developed a multifunctional wound dressing to promote healing of infected wounds by doping puerarin-loaded mesoporous polydopamine nanoparticles into a carboxymethyl chitosan/sodium alginate oxide-based hydrogel. The hydrogel has good injectability, adhesion, and self-healing capabilities, and can be well matched to irregular wounds and against external injuries. The loaded PUE is rapidly released from the hydrogel in response to near-infrared (NIR) laser irradiation, which has a controlled release property. In addition, under NIR laser irradiation, the hydrogel with good photothermal properties exerted good antimicrobial properties through localized high temperature, and exhibited good antioxidant, immune microenvironment modulation, and pro-angiogenic effects through accelerated released PUE. In the E. coli-infected full-thickness skin wounds healing experiments, the hydrogel can effectively kill bacteria, regulate the immune microenvironment, promote collagen deposition and angiogenesis, and significantly accelerate the wound healing, showing promising applications.
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高影响因子
ACS Nano
·
2025
·
IF 16
Jinyang Liu,Xuebo Zhang,Bingjie Zhao,Huan Ling,Yanzhong Li,Kuangshi Sun,Song Chen,Yanxin Zhang,Tianli Zhai,Yunxiang Zhang,Fuyou Li,Qian Liu
Single-molecule tracking offers nanometer resolution for studying individual molecule dynamics but is often limited by sparse labeling to avoid signal overlap. We present Red-Light-Activated Single-molecule Tracking (RE-LAST) strategy to address this challenge utilizing a photoactivatable probe, SiR670. SiR670 combines traditional silicon rhodamine with a photocage called SO, quenching fluorescence via photoinduced electron transfer (PET). Red light triggers SiR670 excitation, generating singlet oxygen that oxidizes the SO cage, halting PET and restoring fluorescence. RE-LAST used red light for both activation and imaging, eliminating harmful UV exposure. This method enables high-throughput single-molecule tracking, achieving approximately 9 times more tracks than conventional methods and allowing detailed classification of CD56 membrane protein motion. Furthermore, in situ imaging of single live cells revealed the effects of triplet quencher and oxygen scavenging system (OSS) on membrane protein dynamics. While triplet quenchers like Trolox had minimal impact on protein movement patterns, OSS significantly accelerated protein movement and increased the proportion of mobile proteins. This approach provides a comprehensive method for investigating membrane protein dynamics in living cells, contributing to further developments in cellular and molecular biology.
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高影响因子
Advanced Optical Materials
·
2025
·Vol. 13
·期 8
·2402764
·
IF 7.2
Jiaxiang Wang,Zunxian Yang,Ye Chen,Hui Zhang,Yue Chen,Yuting Bai,Xudong Jiang,Benfang Liu,Jiajie Hong,Zhezhou Fang,Jinzhu Gao,Zheyu Zhou,Runsen Yu,Xuanyao Song,Zhiyu Yuan,Tailiang Guo,Fushan Li,Yongyi Chen,Zhenzhen Weng
Perovskite quantum dots (PQDs) have emerged as promising candidates for next-generation high-quality lighting and high-definition displays due to their outstanding luminescence properties, characterized by a narrow emission spectrum and tunable color. However, during the purification process involving polar solvents, ligand detachment from the quantum dot surface often induces crystal defects, thereby compromising their long-term stability. Herein, the effects of various post-processing strategies on PQD performance are systematically explored, including the use of oleic acid (OA), didodecyldimethylammonium bromide (DDAB), and their combinations, alongside OA-assisted synthesis. Furthermore, a synergistic post-processing strategy based on DDAB-NaMeS (sodium methanesulfonate) is proposed to elucidate the mechanism of ligand reconstruction on the quantum dot surface during purification. The resulting PQDs demonstrated excellent stability over a storage period exceeding one month, and the corresponding Quantum Dots Light-Emitting Diodes (QLEDs) achieved a peak external quantum efficiency (EQE) of 9.82%, representing a 1.91-fold improvement over standard devices. These QLEDs exhibited exceptional optoelectronic performance, underscoring their potential for application in other sulfonic acid ligands and perovskite-based materials.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Jianxing Feng,Zhenqing Guo,Runli Li,Chaoqun Zhang,Ting Du,Xiang Li,Xuewei Yang,Junchen Zhuo,Yanmin Liang,Yaru Han,Jianlong Wang,Shuo Shi,Wentao Zhang
Recent advances in functionalized micro-nanostructures have enlightened promising non-thermal-dependent antibacterial strategies with broad applications in preventing agrofood spoilage, clinical infections, and environmental pollution caused by pathogens. These advances highlight the need for precise design of efficient and multi-mode bactericides. Herein, photosensitive vitamin B 2 (VB 2 ) was exploited to functionalize semiconductors with limited visible-light response and intrinsic antibacterial activity, while ZnO served as a paradigm for the fabrication of VB 2 -functionalized zinc oxide (VB 2 -ZnO) with persistent antibacterial effects. The enhanced visible photocatalytic activity and the released Zn 2+ in VB 2 -ZnO contribute to potent antibacterial and anti-biofilm effects by disrupting bacterial structures and inducing oxidative stress. Furthermore, the successful fabrication of composite films incorporating VB 2 -ZnO and natural locust bean gum (LBG) exhibited improved physicochemical properties and persistent antibacterial effects, resulting in the shelf-life extension of perishable berries. This work pioneers a novel approach to functionalizing semiconductor photocatalysts with VB 2 photosensitizer, offering novel solutions for ensuring agrofood safety through multi-mechanism antibacterial materials.
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APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Jianfeng Du,Yongpeng Huang,Yikai Yun,Wenjie Wei,Sijie Jiang,Yinxiao Yang,Mengyu Chen,Cheng Li
The deposition of charge blocking layer (CBL) has been proved as an essential approach to improve the unbalanced charge injection and enhance the external quantum efficiency (EQE) of perovskite light-emitting diodes (PeLEDs). Nonetheless, in near-infrared (NIR) PeLEDs, the CBL covering on the typical ZnO electron transport layer (ETL) usually affects the deprotonation process and thereby decreases the crystallinity of perovskite film. In this work, we improve the performance of PeLEDs by atomic layer deposition (ALD) of an ultra-thin (0.43 nm) aluminum oxide (Al 2 O 3 ) CBL between the ETL ZnO and perovskite layer. This CBL improves the charge injection balance and optimizes the morphological and crystalline characteristics of perovskite film. The NIR PeLEDs achieve a peak EQE of 17.0 % with the optimal Al 2 O 3 CBL, representing a 25 % enhancement compared to the control device. In particular, with in-situ electroabsorption (EA) spectroscopy, we discover that the presence of interface permanent dipoles ascribed to the ultra-thin Al 2 O 3 CBL, facilitates the charge injection balance by greatly increasing the built-in potential and reducing the electron injection. Hence, this work paves a practical way to enhance the efficiency of NIR PeLEDs without influencing the deprotonation process.
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Sensors & Diagnostics
·
2023
·
IF 0
Shaoyang Yu,Qiaohong Ke,Fan Cai,Sisi Gong,Rongfu Huang,Chunmei Fan
This work reports on the proof-of-concept of innovative photothermal immunosensing platform for the sensitive screening of YKL-40 in biological fluids by coupling near-infrared light (NIR)-excited platinum nanoparticle (PtNP) with a handheld digital thermometer. First, a sandwiched immunoreaction was carried out on monoclonal rabbit anti-human YKL-40 capture antibody-coated microplate using PtNP-labeled anti-YKL-40 secondary antibody. After formation of the sandwiched immunocomplex, the carried PtNP caused the photothermal conversion under 808-nm laser irradiation relative to the 3,3',5,5'-tetramethylbenzidine (TMB)-H2O2 system, thereby resulting in an increase of the temperature of the detection solution. Under optimum conditions, PtNP-based photothermal immunoassay exhibited a linear relationship within a dynamic range of 0.03 – 100 ng mL-1 at a low limit of detection of 0.014 ng mL-1 YKL-40. High specificity, good reproducibility and long-term stability were achieved with this system. In addition, the accuracy of this method was evaluated for the analysis of human serum samples, giving matched-well results in comparison with human YKL-40 enzyme-linked immunosorbent assay.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2019
·
IF 6.361
Wenxiu Yang,Kun Zeng,Jiaxin Liu,Lechen Chen,Mozhen Wang,Shengchi Zhuo,Xuewu Ge
The combination of the molecular imprinting technology and porous materials is a promising way to obtain high-efficient selective adsorption and separation materials for bioactive macromolecules . In this work, we developed a novel approach to prepare near-infrared (NIR)-light-response inverse-opal lysozyme (Lyz)-imprinted polydopamine/polypyrrole (IO-PDA/PPy-MIP) composite microspheres using micron-sized SiO 2 colloidal crystal microspheres as the sacrificed template. The pore size of the IO-PDA/PPy-MIP microspheres can be tuned from 200 to 800 nm by the size of silica nanoparticles which self-assemble to form the template SiO 2 colloidal crystal microspheres. The IO-PDA/PPy-MIP microspheres show a rapid selective adsorption ability for Lyz due to the inverse-opal macroporous structure. The adsorption capacity exceeds 800 mg/g within 20 min, and the imprinting factor is as high as 24. The bound Lyz molecules can be released rapidly from IO-PDA/PPy-MIP microspheres triggered by the irradiation of NIR laser and remain enough bioactivity to decompose Escherichia coli efficiently. The prepared IO-PDA/PPy-MIP microspheres also exhibit excellent structure stability and good recyclability. The adsorption capacity can remain up to 90% of the initial value after 5 times recycle. This work provides not only a method to prepare novel NIR-light-response inverse-opal macroporous molecularly imprinted microspheres, but also a new perspective on the design of selectively separation materials for the fast, high-efficient recognition and separation of biomacromolecules.
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