Nanoscale
·
2026
·
IF 5.2
Le Luo,Xiaoming Mo,Yusheng Song,Zhentao Du,Sheng Cao,Jinju Zheng,Bingsuo Zou,Jialong Zhao
Quantum-confined CsPbBr3 nanoplatelets (NPLs) are appealing candidates for ultraviolet (UV)/blue photodetectors due to their strong excitonic binding energy and large absorption coefficient. However, the inherent soft lattice and surface defects of CsPbBr3 NPLs lead to poor operational stability, limiting their practical applications. Here, we report an A-site alloying strategy that enhances the structural rigidity and defect formation energy of CsPbBr3 NPLs. The strategy synergistically employs short-chain tetrolic acid (TLA) ligands to passivate uncoordinated Pb2+ ions and formamidinium (FA+) cations to compensate for Cs+ vacancies. This dual repair strategy enhanced both the conductivity and UV irradiation stability of CsPbBr3-based NPLs. As a result, the self-powered UV photodetectors based on Cs0.73FA0.27PbBr3-TLA NPLs exhibited a responsivity of 89 mA W-1, a specific detectivity of 3.99 × 1012 Jones, and an on/off ratio approaching 106 at 0 V bias. Even after 30 days of ambient storage, the device maintained excellent photoresponse and a high specific detectivity of 1.73 × 1012 Jones. Clear images obtained with a custom-built 2D imaging system corroborate the fast response and excellent stability of the device. These results underscore the efficacy of the combined lattice and surface engineering approach for realizing high-performance, durable perovskite NPL-based UV photodetectors.
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INORGANIC CHEMISTRY
·
2026
·
IF 4.6
Bailin Chen,Yansheng Jiang,Hangwei Jia,Shuai An,Xueling Hou,Shilie Pan
Birefringent crystals, as core materials for polarization modulation, hold significant importance for the advancement of laser polarizing technology, high-precision instruments, and other optical communication fields today. However, balancing the deep ultraviolet (DUV) cutoff edge and birefringence remains a demanding challenge. Borophosphates have emerged as a promising research direction for optoelectronic functional materials, but the small birefringence of most borophosphates limits their applications. Here, a novel mixed-coordinated hydroxyborophosphate, NH4B3PO6(OH)3, has been successfully designed and obtained. This compound belongs to the triclinic space group P1 (No. 2), exhibiting pronounced birefringence (the experimental refractive index difference value is 0.057 at 546 nm) and a short DUV cutoff edge below 200 nm. These properties indicate that NH4B3PO6(OH)3 exhibits excellent potential as a DUV birefringent material.
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Science China-Life Sciences
·
2025
·
IF 9.5
Feng Yue,Lin Zishen,Wang Haoran,Men Zhaoyue,Shen Jiakun,Ma Xi
Deoxynivalenol (DON) is a prevalent mycotoxin in animal feed that particularly impacts weaned piglets, causing liver damage, growth retardation, and posing significant public health risks. However, the precise mechanisms underlying DON-induced liver damage and optimal treatment approaches remain unclear. The pregnane X receptor (PXR) holds a pivotal position in hepatic xenobiotic elimination and drug metabolism. This research aimed to explore the involvement of PXR in DON-induced liver injury and evaluate the potential of the PXR agonist, 3-indolepropionic acid (IPA), to alleviate liver damage and associated diarrhea in weaned piglets under practical farming conditions. The results demonstrated that DON initiates p53-mediated hepatocyte apoptosis in weaned piglets. RNA-seq and hepatocyte-specific PXR knockout (PXR-HKO) mice revealed PXR’s regulatory role in DON-induced hepatocyte apoptosis. IPA reduces DON-induced hepatocyte apoptosis in piglets, mice, and hepatocyte cell lines by enhancing PXR expression and facilitating nuclear translocation. Furthermore, AlphaFold3 predictions and Co-IP assays demonstrate that DON diminishes PXR-p53 binding, thereby amplifying p53-mediated apoptotic transactivation. In conclusion, this study elucidates a novel mechanism by which PXR decreases its binding to p53 upon DON exposure, thereby promoting hepatocyte apoptosis. Additionally, it validates the positive impact of IPA in mitigating liver damage and diarrhea caused by DON in weaned piglets.
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Applied Sciences-Basel
·
2025
·Vol. 15
·期 13
·7318
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IF 2.5
Jiawei Cui,Yan Li,Ming Yan
D-allulose is a rare sugar with promising applications in food and health industries, owing to its low caloric value and multiple health benefits. In this study, we systematically investigated a thermostable D-allulose 3-epimerase (TcDAEase) fromThermogemmatispora carboxidivoransfor food-compatible continuous production. The enzyme exhibited remarkable thermostability, with over 70% activity retained at 80 °C, and showed broad pH tolerance across the range of 8.0 to 13.0. Notably, TcDAEase exhibited high catalytic activity toward D-allulose and D-fructose even without the addition of metal ions. Moreover, food-grade Mg2+was identified as enhancing enzyme activity by 14.3%, thus ensuring compliance with Generally Recognized as Safe (GRAS) standards for food applications. To improve industrial applicability, the enzyme was immobilized using a chitosan-diatomaceous earth (DE) matrix via three-step adsorption–crosslinking–embedding strategy. The immobilized TcDAEase achieved 48.7% ± 2.4% activity recovery and retained 90.3% ± 1.5% activity over seven reaction cycles. Furthermore, continuous production of D-allulose was realized in a packed-bed reactor, operating stably at 60 °C, pH 8.0 and 5 mM Mg2+for 150 days, producing 756 kg of D-allulose with a conversion yield exceeding 89.7% of the theoretical maximum. Overall, this study provides a feasible strategy for the continuous and efficient production of high-value-added D-allulose in the food industry.
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JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2025
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IF 6
Weiwei Lu,Xiantao Liang,Jianmin Liu,Fangfen Jing,Mingzhu Jin,Xinyang He,Tao Wang,Rongtai Yu
Heavy metal pollution in water poses severe threats to ecosystems and human health, demanding urgent development of efficient and sustainable adsorbents. Herein, we report a novel amino-functionalized phenolic resin (APF) synthesized via a facile self-assembly strategy using 3-aminophenol and formaldehyde. This approach eliminates the need for toxic crosslinkers or complex post-modification steps, offering a green and scalable route for nanoscale polymer fabrication. The APF particles were engineered with controlled amino group density and hierarchical porosity through optimizing monomer ratios, achieving abundant active sites for multi-metal interactions. The APF adsorbent exhibits exceptional adsorption capacities for both cationic and anionic heavy metals, notably achieving 297.75 mg·g −1 for Cd 2+ – surpassing conventional clay composites and rivaling advanced MOFs. Its multifunctional groups (–NH 2 , –OH) enable synergistic mechanisms: (1) electrostatic attraction for Cr 6+ oxyanions at low pH, (2) chelation-dominated Cd 2+ capture via amino coordination, and (3) ion exchange for Pb 2+ /As 3+ . This work advances the design of cost-effective, multi-mechanistic adsorbents for comprehensive heavy metal remediation.
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Energy Material Advances
·
2023
·
IF 12.9
Zhongyue Wang,Cheng Tang,Zhi Wang,Qing Zhang,Peng Lv,Kehan Yu,Jiajin Zheng,Wei Wei
Developing high-energy cathode for sodium ion batteries (SIBs) that enables 3-electron reaction is the most effective way to reduce high cost and solve range anxiety and safety hazards. Here, a novel NASICON-type Na 4 MnCr(PO 4 ) 3 (NMCP) is synthesized as a high-energy cathode for SIBs. The as-prepared 6.4 wt% carbon-coated NMCP (NMCP@C) cathode annealed at 700 °C delivers a discharge capacity of 107.3 mA h g −1 @0.1C, high rate capability up to 15C, and well capacity retention of 69.3% after 500 cycles at 5C within 1.4 ~ 4.3 V. Meanwhile, it also provides an exciting reversible capacity of 164.3 mA h g −1 @0.1C within 1.4 ~ 4.6 V and an ultrahigh energy density of 523.6 Wh kg −1 . Moreover, high sodium ion diffusion coefficients ( D Na+ , 10 −12 ~ 10 −9 cm 2 s −1 ) demonstrate the superior electrode process kinetics, and both solid solution and 2-phase reactions are involved in the sodium ion extraction/insertion process through ex situ x-ray diffraction analyses. Na 3.3 La 0.3 Zr 1.7 Si 2 PO 12 with 3 wt% Na 2 B 4 O 7 additive (NLZSP(NBO3)) ceramic electrolyte is utilized to assemble NMCP@C//NLZSP(NBO3)//Na solid-state sodium metal batteries for the first time, which reveals an initial discharge capacity of 99.1 mA h g −1 (1.4 ~ 4.3 V) and 121.7 mA h g −1 (1.4 ~ 4.6 V) at 0.1C and an excellent cycling performance (capacity retention of 75.8%/72.6% after 100 cycles at 0.2C) at 30 °C. All these confirm that NMCP@C is a high-energy cathode with great practical potential for all-solid-state SIBs.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2019
·
IF 4.175
Feng-Hua Zhang,Yu-Chong Wang,Lei Wang,Jian Liu,Hong-Liang Ge,Bin Wang,Xin-Yu Huang,Xue-Dong Wang,Zong-Tao Chi,Wan-Feng Xie
Metal oxide semiconductor (MOSC) sensors based on nanocrystalline MoO 3 , In 2 O 3 , and their composites are considered to be very sensitive to detect low concentrations of ethanol, ozone, hydrogen, formaldehyde, and nitrogen dioxide . Here, we firstly introduced In 2 (MoO 4 ) 3 phase, which has excellent negative thermal expansion and high electric conductivity properties, into In 2 (MoO 4 ) 3 @In 2 O 3 crystalline nanocomposites . The gas-sensing performance of the In 2 (MoO 4 ) 3 @In 2 O 3 nanocomposites was studied upon exposure to the ethanol gas with different concentration from 5 to 300 ppm at the optimum temperature (300 °C). What's more, the device possesses ultra-high response of 110 and selectivity to ethanol. Particularly, it can effectively work in high humidity (RH = 80%) with super long-term stability of as long as 90 days, compared with the pristine In 2 O 3 sensor and previous reports. The presented novel In 2 (MoO 4 ) 3 @In 2 O 3 sensor offers great opportunities for future ethanol detection under harsh conditions.
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MICROCHIMICA ACTA
·
2022
·Vol. 190
·期 1
·1-12
·
IF 6.408
Zhong Yaping,Guo Lijuan,Lu Zhentan,Wang Dong
A simple method is reported for hypochlorite determination based on fluorescence 3-aminophenylboronic acid–functionalized molybdenum disulfide quantum dots (B-MoS 2 QDs). B-MoS 2 QDs with strong fluorescence at 380 nm have been successfully synthesized by the amidation reaction between APBA and hydrothermal MoS 2 QDs. Hypochlorite sensing was proposed utilizing the fluorescent quenching effect of 3,3ʹ,5,5ʹ-tetramethylbenzidine dihydrochloride (TMB) on B-MoS 2 QDs and the fast redox reaction between hypochlorite and TMB. The fluorescent quenching effect of TMB to B-MoS 2 QDs was proved to be caused by static dynamic quenching and inner filter effect. A good linear relationship was obtained in the hypochlorite concentration range from 1 to 20 μM, and the limit of detection (LOD) was 36.8 nM. The proposed fluorescent detection assay was simple and fast, taking only 5 min at room temperature. Satisfactory results were obtained in the standard spike recovery tests on tap water and milk samples, which indicate high potential in constructing fluorescent bio-detection assays. Graphical Abstract
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Food & Function
·
2023
·Vol. 14
·期 4
·2200-2211
·
IF 6.1
Dongbao Cai,Xusheng Li,Qingjie Xu,Haiwei Li,Ruijing Liu,Jiali Chen,Xinwei Jiang,Jianxia Sun,Caiyong Lai,Weibin Bai
Testicular hyperthermia induced by unhealthy living habits and pathological or occupational factors can cause spermatogenic dysfunction with an outcome of sub-fertility or even infertility. Cyanidin-3-O-glucoside (C3G) is the most typical anthocyanin in foods that has been recognized as an antioxidant with promising protection for male reproduction. However, its specific effect against testicular hyperthermia and the mechanisms involving its primary gastrointestinal metabolite protocatechuic acid (PCA) are still unexplored. In the present study, testicular hyperthermia in mice was established by employing a single hot water bath at 43 °C for 30 min. C3G and PCA were intragastrically given to investigate their prevention ability against heat stress-induced testicular damage. It was found that C3G and PCA restored the external diameter and thickness, and alleviated atrophy and vacuolation of seminiferous tubules. Simultaneously, C3G and PCA enhanced testicular heat stress tolerance through reducing superfluous eIF2α phosphorylation and stress granule formation. C3G and PCA effectively improved the testicular antioxidant system and regulated the IRE1α-XBP1 pathway, contributing to mitigatory spermatogenesis dysfunction and testicular damage. This finding revealed that anthocyanins were the novel compounds for alleviating testicular damage, and provided a reliable theoretical basis for improving male fertility disturbed by heat stress.
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Petroleum Science
·
2022
·
IF 4.757
Xiao-Yi Liu,Xiu-Ping Li,Rong-Xiang Zhao
Ce 2 (MoO 4 ) 3 was synthesized by a simple reflux method using cerium nitrate hexahydrate and ammonium molybdate as reactants. The as-prepared Ce 2 (MoO 4 ) 3 was characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), Scanning electron microscope (SEM), and X-ray photoelectron spectroscopy (XPS). The removal of dibenzothiophene (DBT) in model oil was studied using Ce 2 (MoO 4 ) 3 as catalyst and oxygen as oxidant. The reaction factors such as reaction temperature, amount of catalyst, and sulfide type on sulfur removal were researched. The results prove that both Ce 3+ and MoO 4 2- play significant role in the conversion from DBT to DBTO 2 . The Ce 2 (MoO 4 ) 3 catalyst has an excellent performance for the sulfur removal of DBT. Under the optimum reaction conditions, sulfur removal of 99.6% was obtained. After recycling five times, no significant loss in catalyst activity of Ce 2 (MoO 4 ) 3 . Mechanism of aerobic oxidative desulfurization was proposed based on the experiment of free radical capture and infrared characterization.
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JOURNAL OF SOLID STATE CHEMISTRY
·
2022
·
IF 3.656
Cong Liu,Qibin Zhu,Zhonghui Zhu,Chen Sun,Yimin Xuan,Kai Zhang
Foreigner element doping is one of effective strategies to promote photocatalytic reaction. Herein, a convenient one-step solvothermal method is applied to enable the isomorphic substitution of In 3+ in In(OH) 3 by Bi 3+ . The composition and microstructure of the photocatalysts were mainly obtained by X-ray diffraction (XRD), scanning electron microscope (SEM) and transmission electron microscope (TEM). UV–Vis diffuse reflectance and photoluminescence (PL) spectroscopy revealed the optical properties of photocatalysts. The surface properties of photocatalysts were mainly characterized by X-ray photoelectron spectroscopy (XPS). Theoretical calculations were used to reveal the reaction mechanism. The results indicated that CO production rate and selectivity of Bi 3+ doped In(OH) 3 are much higher than that of the pure In(OH) 3 , which could be attributed to the extended solar spectral response, the enhanced CO 2 adsorption capacity and the accelerated photogenerated carriers separation. The current work verifies the potential application of isomorphic substitution as an efficient route for solar fuel production.
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Jia Cheng Qian,Dan Liu,Li Ping Lin,Wen Jing Zhu,Ren Xiang Tan
Kimchi is a globally consumed food with diverse health-benefits, but the low-abundance bioactive compounds in kimchi remain largely neglected. Here we show that kimchi contains a family of low-abundance (0.5–1.6 μg/g, dried weight) high-order indole oligomers derived from indole-3-carbinol (I3C), a breakdown product released from cruciferous vegetables used for producing the traditional subsidiary food. The structure determination of such complex molecules was accomplished by synthesizing linear indole oligomers as standard materials followed by the LC–HR–MS analysis. One indole tetramer (LTe2) is substantially toxic to tumor MV4-11 (IC 50 = 1.94 μM) and THP-1 cells (IC 50 = 7.12 μM). Collectively, the work adds valuable information to the knowledge package about kimchi, and may inspire the generation of indole-based molecules, to which many drugs belong.
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危险品化学品经营许可证（带存储）