MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 8
·1-9
·
IF 6.408
Zhuang Zhenjing,Zhang Chunyan,Yu Zhengdi,Liu Wenyuan,Zhong Yajun,Zhang Jingyun,Xu Zhihui
CuO nanorods bearing Au nanoparticles (Au/CuO nanocomposites) were prepared by a solution-phase synthesis and exhibited efficient hydroquinone (HQ)-oxidase activity with good specificity. The Au/CuO nanocomposites effectively catalyzed the oxidation of colorless HQ to brown benzoquinone with an absorbance maximum at 376 nm but did not catalyze the conversions of catechol or resorcinol. Kinetic studies indicated that the Au/CuO nanocomposites exhibited a strong affinity for HQ, with a Michaelis–Menten constant of K m = 0.33 mM. Owing to the high catalytic activity and specificity, a strong color was observed at low concentrations of HQ. Quantitative measurement of HQ was performed via colorimetric analysis, which yielded a detection limit of 3 μM with a linear range of 5–200 μM. This colorimetric sensor was successfully applied to an HQ assay of real water samples with satisfactory results. Graphical abstract
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2018
·Vol. 410
·期 10
·2629-2636
·
IF 3.307
Yu Huan,Chen Xinfeng,Yu Long,Sun Mingtai,Alamry Khalid A.,Asiri Abdullah M.,Zhang Kui,Zapien Juan Antonio,Wang Suhua
In this study, we have developed a facile method for preparation of highly fluorescent Au nanoclusters (AuNCs) using 11-mercaptoundecanoic acid (MUA) as both the reducing and stabilizing agent. The as-prepared MUA functionalized AuNCs (MUA-AuNCs) have good water solubility, excellent photostability, and strong fluorescence emission at 610 nm with a quantum yield of 7.28% in water. The fluorescence of MUA-AuNCs was first quenched by copper ions through electron transfer, subsequently caused obvious restoration by competitive effect after adding penicillamine, making it a potential fluorescent sensor for penicillamine with a detection limit of 0.08 μM. Furthermore, the newly designed fluorescence “on-off-on” assay was explored for the measurement of penicillamine in complex real water and urine samples with satisfactory results.
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Nanomaterials
·
2022
·Vol. 12
·期 8
·1370
·
IF 5.719
Cong Tian,Zhe Tang,Yike Hou,Asim Mushtaq,Shafaq Naz,Zhangsen Yu,Jabeen Farheen,Muhammad Zubair Iqbal,Xiangdong Kong
Significant attention is paid to the design of magnetoplasmonic nanohybrids, which exploit synergistic properties for biomedical applications. Here, a facile method was employed to prepare plasmonic magnetic Au-MnO heterostructured hybrid nanoparticles for imaging-guided photothermal therapy of cancers in vitro, with the view to reducing the serious drawbacks of chemotherapy and gadolinium-based contrast agents. The biocompatibility of the prepared Au-MnO nanocomposites was further enhanced by Food and Drug Administration (FDA)-approved triblock copolymers Pluronic®F-127 and chitosan oligosaccharide (COS), with complementary support to enhance the absorption in the near-infrared (NIR) region. In addition, synthesized[email protected]nanocomposites exhibited promising contrast enhancement in T1MR imaging with a good r1relaxivity value (1.2 mM−1s−1), demonstrating a capable substitute to Gd-based toxic contrast agents. In addition, prepared[email protected]hybrid nanoparticles (HNPs) produced sufficient heat (62 °C at 200 μg/mL) to ablate cancerous cells upon 808 nm laser irradiation, inducing cell toxicity, and apoptosis. The promising diagnostic and photothermal therapeutic performance demonstrated the appropriateness of the[email protected]HNPs as a potential theranostic agent.Keywords:plasmonic nanoparticles;magnetic nanocomposites;T Magnetic contrast agents;photothermal therapy;cancer theranostics
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ChemSusChem
·
2022
·Vol. 15
·期 13
·e202200092
·
IF 9.14
Xiaohong Hu,Zhijian Li,Haiyong Wang,Haosheng Xin,Song Li,Chenguang Wang,Longlong Ma,Qiying Liu
Graphical Ring-opening : Au/ZrO 2 catalysts with excellent ring-opening hydrogenolysis ability are developed for the selective hydrogenolysis of 5-hydroxymethylfurfural and furfural to produce 2-hexanol and pentanol (1-pentanol and 2-pentanol). The Au-O−Zr interfaces with Lewis acid and metal functionalities play key roles for obtaining the target products with high yield. 2-Hexanol (2-HOL) is a versatile biomass-derived platform molecule for synthesis of liquid transportation fuels, lubricants, or detergents. Herein, a one-step preparation of 2-HOL using 5-hydroxymethylfurfural (HMF) as a substrate was reported for the first time. Several Au-based catalysts supported on different metal oxides were prepared to explore the relationship between carrier and catalytic activity. The results showed that the highest 2-HOL yield of 65.8 % was obtained at complete HMF conversion over the 5 %Au/ZrO 2 catalyst. The 5 %Au/ZrO 2 catalyst exhibited excellent durability after five consecutive recycling runs, while confirming its remarkable ring-opening hydrogenolysis on other biomass-derived furanics, furfural, with a total yield of 1-pentanol and 2-pentanol of 67.4 %. The distinguished ring-opening hydrogenolysis performance of the Au/ZrO 2 catalyst originated from a synergistic effect between the interfacial Au-O-Zr oxygen vacancies-induced Lewis acidic sites (activating C−OH/C=O bonds) and metallic Au (activating H 2 ). This work provides a possibility for producing 2-HOL from HMF with high yield, expanding the sustainable application of lignocellulosic biomass.
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COLLOIDS AND SURFACES B-BIOINTERFACES
·
2022
·
IF 5.999
Ziyi Wang,Zhilong Xu,Xiangdong Xu,Juqun Xi,Jie Han,Lei Fan,Rong Guo
Noble metals act as nanozymes that can generate reactive oxygen species (ROS) by catalysis to induce apoptosis of tumor cells for cancer therapy. But they are easy to aggregate, which will affect their further application. Carbon materials are often used as the carrier of noble metals to improve their catalytic performance. However, designing a composite structure to build an efficient carbon/noble metal hybrid nanozyme with high catalytic performance for tumor therapy is still a significant challenge. In this work, a core-in-shell structure nanozyme composed of gold nanoparticles (AuNPs) embedded in nitrogen-doped hollow carbon nanoshells (AuNPs@N-HCNs) were fabricated, which exhibited peroxidase-like (POD-like) and oxidase-like (OXD-like) activity. Compared with core-out-of-shell structure composite, the AuNPs@N-HCNs showed a better ability to generate ROS to kill tumor cells. Furthermore, AuNPs@N-HCNs also exhibited satisfactory photothermal conversion properties, which helped build a platform for photothermal therapy. Meanwhile, the enzyme activity produced by AuNPs@N-HCNs increased significantly under light irradiation . Comparing the size of AuNPs in carbon shell, 15 nm AuNPs were better than 2 nm in both enzyme-like activities and in vivo therapeutic effect. In vitro and in vivo studies demonstrated that under the synergistic effect of light-enhancing nanozyme catalysis and photothermal therapy, AuNPs@N-HCNs could induce cancer cell apoptosis and destroy tumors effectively, which provided evidence for the feasibility of tumor catalytic-photothermal treatment.
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MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Zhaofei Liu,Xinyue Wang,Yuhang Wei,Weiwei Xie,Song Li,Zhiming Chen
As a biomarker of endocrine gland diseases, the rapid and accurate determination of dopamine has a great significance. The aim of this study was to improve the dopamine biosensing performance of the Fe 3 O 4 @CS-Au-Lac (laccase immobilized on Fe 3 O 4 @CS-Au nanocomposites) by using the photothermal effect of magnetic carriers. Electrochemical impedance spectroscopy measurements revealed that the Fe 3 O 4 @CS-Au nanocomposites enhanced the electron transfer between laccase and the electrode. The Fe 3 O 4 @CS-Au-Lac biosensor presented an ultra-fast response to substrates, accurately detected dopamine within 0.2 s. Dopamine biosensing assays demonstrated that the Fe 3 O 4 @CS-Au-Lac biosensor possessed high sensitivity, remarkable tolerances towards organic compounds and metal ions, and excellent selectivity and stability. Amperometric curves indicated that the illumination brought a higher current to the biosensor compared to the dark environment. The Fe 3 O 4 @CS-Au-Lac biosensor held a low detection limit of 0.79 μM (S/N = 3) and a broad linear range of 1–1000 μM under the irradiation. Most significantly, the Fe 3 O 4 @CS-Au-Lac biosensor provided reliable results in the photothermal analysis of dopamine in synthetic urine samples. This finding paves the way for using the Fe 3 O 4 @CS-Au-Lac biosensor for photothermal detection of dopamine in biomedical applications.
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CHEMICAL PAPERS
·
2019
·Vol. 74
·期 6
·1839-1847
·
IF 1.246
Liu Li,Hao Yan-jun,Li Zhen,Chen Cheng,Wu Ming-yu,Feng Shun
Abstract One gold nanoparticles (NPs) modified zeolitic imidazolate framework material was prepared from cobalt(II) oxide (Au@ZIF-67). The morphology, elemental composition and colorimetric property of it was characterized by UV–Vis spectrophotometer, field-emission scanning electron microscope, transmission electron microscope and energy-dispersive spectroscopy. In presence of 20 amino acids making up proteins, the feature absorbance of Au@ZIF-67 solution at 592 nm decreased accordingly only in presence of cysteine (Cys) and kept almost no change whenever added other 19 amino along or mixed together. Therefore, either naked eye and visible spectrometric methods were proposed for Cys detection with detection limits of 0.5 µM and 0.1 µM, respectively. The distinguished color change, short reaction time, high specificity and sensitivity made Au@ZIF-67 a promising visible colorimetric probe for Cys in water. Moreover, the potential mechanism was studied. The result indicated that Au NPs played as a key role. Graphic abstract
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JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY
·
2015
·Vol. 15
·期 6
·4276-4284
·
IF 1.556
Zhu Yuanna,Yang Ping,Miao Yanping,Cao Yongqiang,Yang Yang
The photoluminescence (PL) quenching of thioglycolic acid (TGA)-capped CdTe quantum dots (QDs) by glutathione (GSH)-capped Au nanocrystals (NCs) were investigated via PL degradated measurement. It was found that the PL of the QDs with several sizes can be effectively quenched by GSH-Au
NCs. The size and PL peak wavelengths of QDs have no significant impact on the quenching processing. Through the characterizations of UV-visble absorption spectrum, Zeta potential and steady-state, and time-resolved fluorescence spectroscopy, it was proved that the PL quenching of the QDs
by GSH-Au NCs was attributed to static quenching caused by the formation of a QDs- Au complex. The binding parameters calculated from modified Stern–Volmer equation showed that the binding affinities between the GSH-Au NCs and CdTe QDs was in the order of 105 L ·mol−1,
which indicated that the binding force was larger and the effective quenching occurred. The thermodynamic parameters studies revealed that the binding was characterized by positive enthalpy and positive entropy changes and hydrophobic force played a major role for QDs-Au association. In addition,
all the quenching experiments were conducted in the phosphate-buffered saline (PBS) buffer solution at pH 7.4 and the investigation is expected to be applied in the biology.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Xiangqian Kong,Wenyan Xia,Yuruo Qiu,Bingrui Zhao,Yuan Zhao,Wei Ma
Polystyrene (PS) plastics were potentially present in consumer products through the use of plastics packaging. The migration and enduring presence for bioaccumulation posed significant threats to human health and the environment. It was significant to develop a simple and reliable approach for sensitive PS plastics detection. In this study, Au-Bi 2 Se 3 hybrid nanosheets (NSs) were designed and utilized as SERS probes for the detection of PS plastics. The electron transfer from Bi 2 Se 3 to AuCl 4 − induced the formation of Au NPs on the surface of thin Bi 2 Se 3 NSs. Au-Bi 2 Se 3 hybrid NSs were found to display enhanced SERS activity by using PS plastics as Raman tags. Besides the unique electromagnetic enhanced mechanism from Au NPs, the introduction of Bi 2 Se 3 supported the Dirac plasmon polaritons in electromagnetic modes, and Bi 2 Se 3 with high dielectric constants inhibited the decay of electromagnetic waves. Au-Bi 2 Se 3 hybrid NSs engineered SERS sensor achieved stable and sensitive detection of PS plastics in essence liquid. Different sized PS plastics ranging from 89.3 nm to 1.48 μm were detected with the LODs of ppm levels. These findings highlight the potential of Au-Bi 2 Se 3 hybrid NSs as effective and universal SERS substrates for detecting different sized plastics in real samples.
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ADVANCED FUNCTIONAL MATERIALS
·
2023
·Vol. 34
·期 7
·2310730
·
IF 19
Qing-Ling Hong,Bin Sun,Xuan Ai,Xin-Long Tian,Fu-Min Li,Yu Chen
Ammonia (NH 3 ) is an essential chemical for agricultural production and a promising next-generation hydrogen-rich fuel. The electrocatalytic nitrate (NO 3 − ) reduction reaction (NO 3 RR) to NH 3 provides a sustainable and low-energy method to replace industrial NH 3 synthesis. However, the NO 3 − to NH 3 conversion is limited by the complex eight-electron and nine-proton reduction processes, thus it is highly desirable to develop efficient electrocatalytic materials to overcome the kinetic barrier of NO 3 RR. Herein, Au nanocrystals (Au-NCs) modified holey PtTeAu metallene (PtTeAu-ML) heteronanostructures (Au-NCs/PtTeAu-MLs) are designed through phase and interface engineering, which achieve the high NH 3 yield (3.499 mg h −1 mg cat −1 ) and Faradaic efficiency of 96.3% for NO 3 RR at −0.03 V versus RHE. Detailed investigations reveal that the introduction of Te atoms significantly inhibits the high activity of Pt atoms for hydrogen evolution reaction that competes with NO 3 RR. Density functional theory results demonstrate that Au atoms further modulate the electronic structure of Pt in PtTe-MLs, resulting in the upward shifted d band center of Pt and in turn the optimized NO 3 RR process on PtTeAu-MLs. Furthermore, Au-NCs allows the sustainable sunlight energy to accelerate the NO 3 RR kinetics at PtTeAu-MLs because of the localized surface plasmon resonance of Au, inducing a higher NH 3 yield of 4.684 mg h −1 mg cat −1 under light irradiation condition.
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Advanced Sustainable Systems
·
2025
·
IF 6.1
Haiyu Ma,Jian Li,René Hübner,Xingyu Tao,Kairui Xu,Mingjia Lu,Jiakun Du,Muwu Li,Zhikun Zheng,Wei Liu
Platinum-based electrocatalysts represent the most promising candidates for the methanol oxidation reaction (MOR) in direct methanol fuel cells. However, the wide commercialization of platinum-based electrocatalysts faces significant challenges, including high material costs, insufficient catalytic activity, limited operational durability, and susceptibility to CO poisoning. To overcome these issues, a new Au-doped Pt-Co aerogel (AG) is fabricated by the facile one-pot aqueous-solution heteroatom doping method. This catalyst demonstrates good electrocatalytic performance for MOR, combining both high activity and remarkable stability. The Au 1 -Pt 67 Co 33 AG with optimized Au doping amount exhibits outstanding mass activity, which is 1.7 times that of its undoped Pt 67 Co 33 AG counterpart and 4.6 times that of the commercial Pt/C catalyst. Furthermore, the Au 1 -Pt 67 Co 33 AG demonstrates significantly enhanced long-term stability under continuous operation. Density functional theory calculations indicate that Au doping reduces the energy barriers for methanol dehydrogenation and lowers the total energy barriers for the *CO oxidation steps, facilitating the rapid dehydrogenation of CH n OH and faster conversion of *CO, thereby significantly enhancing the electrocatalytic activity and stability of the Au 1 -Pt 67 Co 33 AG toward MOR.
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Journal of Materials Chemistry A
·
2025
·
IF 9.5
Yu Liu,Rong Peng,Ying Xu,Xiaoqiong Liu,Yi Song,Wenwei Liu,Wu Tianli,Junwei Zhang,Tao Li
Glycerol, as a renewable fuel with high energy density, has broad application prospects in green energy conversion.However, its electrocatalytic oxidation is limited by the activity and selectivity of catalysts, which severely restricts the efficient release of energy. In this work, we report a facile co-reduction synthesis of bimetallic Au-Ti nanoparticles featuring abundant Au-TiO x interfaces, which nearly doubled the mass activity for glycerol electrooxidation from 1.420 A mg Au -¹ to 2.717 A mg Au -¹, and presented an impressively high mass activity retention after the stability test. In situ attenuated total reflection surface-enhanced infrared absorption spectroscopy (ATR-SEIRAS) analysis confirms that Au-Ti alloy shows a deeper oxidation behaviour. Density functional theory (DFT) calculations further reveal that the formation of Au-TiO x interfaces gives rise to bifunctional synergistic sites, which facilitate the cooperative adsorption of glycerol and hydroxyl species, thereby overcoming the limitations of single-type active sites on Au/C. Meanwhile, CO adsorption further enhances the binding of hydroxyl groups, synergistically promoting deep oxidation of glycerol.
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