Environmental Science-Water Research & Technology
·
2024
·Vol. 10
·期 8
·1785-1794
·
IF 3.5
Jun Zhang,Shenjun Wang,Yuhao Wu,Jiahai Ma
In advanced oxidation systems, the promoting effect of bicarbonate is relatively overlooked. Bicarbonate, as an inorganic anion widely present in natural waters, is extremely important for water treatment. Therefore, bicarbonate was added to a PDS/Cu2+ system to investigate the degradation mechanisms of organic contaminants. The generation of alkyl radicals in the PDS/Cu2+/HCO3− system was first demonstrated through Electron Paramagnetic Resonance (EPR) testing. This study reveals that the introduced bicarbonate ions undergo transformation into alkyl radicals. The presence of alkyl radicals promotes the cycling of monovalent, divalent, and trivalent copper ions, facilitating the degradation of contaminants. The production of monovalent and trivalent copper ions in the reaction system was confirmed through UV-vis absorption spectroscopy and quenching experiments. Furthermore, the change in the oxidation state of copper ions was further confirmed through EPR testing. These findings not only shed new light on the degradation mechanism of the PDS/Cu2+ system in the presence of bicarbonate but also open up new avenues for the further application of bicarbonate in advanced oxidation processes.
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DOI
高影响因子
TALANTA
·
2019
·
IF 4.916
Xuan Wang,Caicheng Long,Xiaoyan Xu,Taiping Qing,Peng Zhang,Bo Feng
Micrococcal nuclease (MNase) is a nonspecific endo-exonuclease that digests single-stranded/double-stranded DNA and RNA. The existence of MNase can serves as an important diagnostic biomarker of Staphylococcus aureus ( S. aureus ) infection. However, most of the substrates in MNase-based sensors are single-stranded DNA, which could also be digested by exonuclease I or S1 nuclease and interfere the MNase detection. In this work, we developed a highly selective fluorescent method for MNase detection using a specific dsDNA and nucleic acid dye SYBR Green I (SGI) as the indicator. After rational design, an AT-rich dsDNA with 3′ protruding termini was screened as the high-specific substrate of MNase assay and efficient enhancer of SGI. The AT-rich dsDNA substrate can resist the digestion of other exonuclease and greatly enhance the fluorescence of SGI. This high-specific substrate-based probe can detect MNase in buffer as well as biological sample with highly selectivity . Moreover, this method was also applied to monitor the MNase secreted by S. aureus . Thus, the proposed MNase-based assay has a strong potential to identify S. aureus in food safety and microbial infection due to its excellent analytical sensitivity and high selectivity.
研究领域:
微生物学
·
分子生物学
·
医学诊断
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DOI
PubMed
高影响因子
Nanomaterials
·
2022
·Vol. 12
·期 18
·3121
·
IF 5.719
Zhangwei He,Runnan Yu,Wanrong Song,Yongshuai Gong,Hui Li,Zhan’ao Tan
Bismuth triiodide (BiI3) is a particularly promising absorber material for inorganic thin-film solar cells due to its merits of nontoxicity and low cost. However, one key factor that limits the efficiency of BiI3solar cells is the film morphology, which is strongly correlated with the trap states of the BiI3film. Herein, we report a coordination engineering strategy by using Lewis base dimethyl sulfoxide (DMSO) to induce the formation of a stable BiI3(DMSO)2complex for controlling the morphology of BiI3films. Density functional theory calculations further provide a theoretical framework for understanding the interaction of the BiI3(DMSO)2complex with BiI3. The obtained BiI3(DMSO)2complex could assist the fabrication of highly uniform and pinhole-free films with preferred crystallographic orientation. This high-quality film enables reduced trap densities, a suppressed charge recombination, and improved carrier mobility. In addition, the use of copper(I) thiocyanate (CuSCN) as a hole transport layer improves the charge transport, enabling the realization of solar cells with a record power conversion efficiency of 1.80% and a champion fill factor of 51.5%. Our work deepens the insights into controlling the morphology of BiI3thin films through the coordination engineering strategy and paves the way toward further improving the photovoltaic performances of BiI3solar cells.
研究领域:
材料科学
·
光伏技术
·
理论计算
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2017
·
IF 6.035
Bin Jiang,Haozhen Dou,Luhong Zhang,Baoyu Wang,Yongli Sun,Huawei Yang,Zhaohe Huang,Hanrong Bi
Deep eutectic solvents (DESs), as a new generation of designer solvents , were firstly employed to fabricate the supported liquid membranes (SLMs) for the olefin/paraffin separation via facilitated transport. The novel CuCl/DESs-SLMs were prepared by impregnating the mixture of choline chloride-glycerol based DESs and copper (I) chloride (CuCl) into the microporous nylon membranes. The results of FTIR, 1 HNMR and mass spectrometry (MS) confirmed the existence of various Cu (I)-containing anionic species and hydrogen-bond networks in the membrane liquid of CuCl/DESs. The CuCl/DESs-SLMs were characterized by scanning electron microscope (SEM), contact angle measurement and weight analysis, and their performances of CuCl/DESs-SLMs were evaluated by the C 2 H 4 /C 2 H 6 separation experiments. The effects of DESs composition, CuCl concentration , operation pressure and temperature were investigated systemically. It was found that the activity and chemical stability of Cu (I)-containing anionic species were enhanced through the hydrogen-bond interactions between the anionic species and DESs, which significantly increased the permeability of C 2 H 4 and selectivity of C 2 H 4 /C 2 H 6 . Compared with other studies, the CuCl/DESs-SLMs exhibited comparable permeability and higher selectivity up to 20 for C 2 H 4 /C 2 H 6 . In conclusion, the CuCl/DESs-SLMs provided a promising method for the C 2 H 4 /C 2 H 6 separation.
研究领域:
化学工程
·
材料科学
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DOI
高影响因子
MOLECULES
·
2025
·Vol. 30
·期 5
·1103
·
IF 4.6
Bin Zhang,Xiaoyu Wei,Peiwen Du,Huangqun Luo,Lanfang Hu,Liping Guan,Guangying Chen
Polysaccharides are very promising molecules in the field of pharmacotherapy. Knowing this, the aim of this study was to extract, characterize, and evaluate the action of the polysaccharides in noni juice, using biological models of Type 2 diabetes mellitus processes. In this study, one polysaccharide named NJSPd−1 was separated from fermented noni fruit juice. The characterization assay showed that NJSPd−1 had a molecular weight ( Mw ) of 18,545 Da. NJSPd−1 consisted of galacturonic acid, galactose, rhamnose, and arabinose, with a molar ratio of 28.79:20.34:19.80:18.84 according to HPGPC analysis, and the glycosidic bond mainly included →4)- α -D-GalA p -(1→, 4)- β -D-Glc p -(1→, →2)- α -L-Rha p -(1→, and →3)- α -L-Ara f -(1→. The prevention of oxidative stress activities by NJSPd−1 was evaluated using high-glucose-induced oxidative stress in HepG2 cells. In vitro results showed that NJSPd−1 influenced the downregulation of the proteins and genes Nrf2, Keap1, HO-1, and NQO1 in HepG2 cells. These results suggest that NJSPd−1 exerted a protective effect against oxidative stress in HepG2 cells by activating the Nrf2/HO-1/NQO1 signaling pathway.
研究领域:
药理学
·
生物化学
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DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Jiajia Wang,Li Li,Ruyi Wei,Renfeng Dong
Here, we report the first PbS quantum dot (QD)-based micromotors with NIR-I light-driven photocatalytic propulsion and NIR-II fluorescence. Under the irradiation of NIR-I light (808 nm), PbS QD-doped cuprous oxide (Cu2O@PbS) micromotors can display efficient propulsion in a variety of biocompatible fuels such as malic acid, glucose, and urea. Among them, the Cu2O@PbS micromotors exhibit the best propulsion performance in a very low concentration of malic acid, with an average speed as high as 11.86 μm/s. The enhanced NIR-I photocatalytic activity of Cu2O@PbS micromotors benefits from the doping of NIR-I PbS QDs that can be excited by NIR-I light and exhibit high electron transport efficiency. The doped PbS QDs can effectively increase the absorption efficiency of the micromotors in the NIR-I region while also inhibiting the recombination of photogenerated electron–hole pairs. Interestingly, due to the presence of NIR PbS QDs, the Cu2O@PbS micromotors demonstrate prominent and stable NIR-II fluorescence (emission wavelength: 1100 nm), which offer promising potential for visualization of their position in vivo. In comparison to other photocatalytic micromotors, the simple fabrication strategy, excellent NIR-II fluorescence, together with the NIR-I light-dependent propulsion behavior of the current Cu2O@PbS micromotors, thus pave the way for further development of advanced smart “robots” for intelligent biomedical applications.
研究领域:
纳米技术
·
生物医学工程
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材料科学
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DOI
高影响因子
Advanced Optical Materials
·
2022
·Vol. 10
·期 20
·2200865
·
IF 10.05
Kai Han,Jiance Jin,Binbin Su,Jianwei Qiao,Zhiguo Xia
Metal clusters with color-tunable radioluminescence have attracted growing attention as X-ray detection materials. However, they are generally less scintillation-efficient due to the coexistence of multiple exciton recombination centers. Herein, two new zero-dimensional copper(I)-based clusters (DIET) 3 Cu 3 X 3 (DIET = 1,3-Diethyl-2-thiourea, X = Cl, Br) are designed, which support the single channel photon emission (Cu cluster centered, CC) to enhance the scintillation performance. Those DIET ligands (L) anchoring with copper(I) ions not only generate direct Cu L bonds, but also form a disorder [Cu 3 X 3 ] cluster, which results in the intense X-ray absorption. (DIET) 3 Cu 3 Br 3 with low halogen electronegativity further weakens halogen-to-ligand charge transfer (XLCT) emission, enabling enhanced quantum efficiency (≈69%) and scintillation performance comparable to commercially available Lu 3 Al 5 O 12 :Ce. Moreover, the flexible thin film counterpart demonstrates legible X-ray imaging with high spatial resolution of 11.71 lp mm −1 . This study provides a feasible design principle to discover new metal cluster-based scintillators and to further expand their radiation detection applications.
研究领域:
材料科学
·
辐射探测
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DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2022
·
IF 8.008
Jun Li,Yao-Yao Fan,Jie Wen,Jing Zhang,Zhi-Qi Zhang
The HIV-Ι trans-activation responsive (TAR) RNA–trans-activator of transcription (Tat) protein complex is crucial for the efficient transcription of the integrated human immunodeficiency virus-I genome and is an established therapeutic target for AIDS diagnosis and treatment. Developing a sensitive strategy for the TAR RNA-binding ligand assay could provide antiviral leads with a radically new mechanism for the treatment of AIDS. Herein, a new TAR RNA-binding ligand assay platform was established using a signal amplification strategy that combines aggregation-induced emission (AIE) with a metal-enhanced fluorescence (MEF) concept. The tetraphenylethylene (TPE) derivative was labeled on the Tat peptide as a fluorescent molecule, while the TAR RNA was immobilized on the surface of the Fe3O4@Au@Ag@SiO2 nanoparticles (NPs) to specifically bind the TPE-Tat peptide. The TPE-Tat peptide was weakly emissive itself while emitting strongly in the NP–TAR–TPE-Tat complex by the AIE and MEF signal amplification effect. It was confirmed by known Tat peptide competitors that this system could be applied to the screening and detection of TAR RNA-binding ligands because they could replace the TPE-Tat peptide from the complex and make the system fluorescence decrease. When this system was adopted to test four candidate ligands, it was found that bisantrene had a favorable TAR RNA-binding ability. The proposed AIE–MEF strategy not only provides a sensitive and reliable method for the TAR RNA-binding ligand assay but also can avoid the influence of ligands on fluorescent detection in the conventional displacement assay.
研究领域:
病毒学
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分子生物学
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生物医学工程
·
化学生物学
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DOI
PubMed
高影响因子
Inorganic Chemistry Frontiers
·
2023
·Vol. 11
·期 1
·156-163
·
IF 7
Jiajing Wu,Jing-Li Qi,Yue Guo,Shufang Yan,Wenlong Liu,Sheng-Ping Guo
Hybrid copper halides have been rapidly developed because of their high photoluminescence quantum yield (PLQY), good water resistance, and variable structures; nevertheless, the controlled synthesis and interconversion of multiple hybrid copper halides containing different coordination geometries are rarely reported. In this study, using ethyltriphenylphosphonium as the templating cation [EtPh3P]+, three stable hybrid copper bromides with diverse inorganic anion skeletons, (EtPh3P)CuBr2 (112), (EtPh3P)2Cu2Br4 (224), and (EtPh3P)2Cu4Br6 (246), were synthesized by carefully tuning the feeding ratio of CuBr and (EtPh3P)Br. The emission peaks were located at 536, 546, and 580 nm with optical absorption edges of 3.64, 2.91, and 2.82 eV, respectively, showing a gradual redshift as the inorganic units change from a monomer (112) to dimer (224) and then to a tetramer (246). More interestingly, multiple solvents, including methanol (MeOH), ethanol (EtOH), isopropanol (IPA), acetic acid, ethylene glycol, and water with heat, can induce the spontaneous conversion of 112 and 224 to 246, which is attributed to the affinity of the organic salt with the solvent. Additionally, the crystal structure can transform from 246 into 112 (224) or can undergo a reversible dynamic conversion between 112 and 224 using the crystallization method. This work not only provides a strategy to adjust the inorganic units of the crystals but also to achieve multi-state structural transitions, making them viable candidates for next-generation multifunctional optoelectronic devices.
研究领域:
材料科学
·
化学
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DOI
高影响因子
Food Science and Technology
·
2021
·
IF 1.718
LI Tian-Xiao,LUO Cheng,GENG Zong-Ze,JIANG Zhong-Rong,JI Ling-Bo,SHENTU Hong-Qian,XIE Yun-Fei,HU Jun,LIU Yuan-Fa,LI Dong-Liang
To study the caramel reactions of disaccharides with water, the type I maltose caramel products (MCPs) and sucrose caramel products (SCPs) at three reaction stages were yielded and their reaction rates, UV absorptions, flavor compounds, and antioxidant activities were also detected. It was found that the caramel reactions of sucrose were faster than those of maltose and their reaction rates quickly increased to a high level in the middle stage. UV absorption of SCP in the late stage at 305 nm was much stronger than those of MCPs. Both the MCP and SCP obtained at 180 °C and 4 min had the highest concentrations of 5-hydroxymethylfurfural and total flavor compounds. Moreover, the total flavor concentrations of SCPs were much larger than those of MCPs and the antioxidant effects of SCPs were also stronger. Thus, a preferred condition for both two disaccharide caramel reactions was suggested at 180 °C for 4 min and the sucrose caramels could give better flavors than maltose caramels.
研究领域:
食品科学
·
化学
·
营养学
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DOI
高影响因子
Russian Journal of Non-Ferrous Metals
·
2022
·Vol. 63
·期 1
·46-56
·
IF 0.691
He Puqiang,Xianzhi Hu,Futing Zi,Chaowu Wang
Abstract Effective gold recovery from thiosulfate leaching solution is important for the development of non-cyanide gold leaching technology. Herein, a novel functionalised activated carbon (denoted as AC-SH) that can effectively adsorb Au(I) from thiosulfate solution was synthesised using an environment-friendly route via the solid-phase reaction of activated carbon with 2-mercaptobenzoxazole. In the batch experiments, the effects of contact time, solution pH, temperature, and initial Au(I) concentration on the adsorption performance of AC-SH were investigated. Langmuir isotherm and pseudo-second-order kinetic models suitably described the adsorption of Au(I). Additionally, FT-IR, SEM, EDS, and XPS data revealed that AC-SH was successfully synthesised and Au(I) adsorption on AC-SH proceeded through chelation with Au(I) via the S‑containing functional group. The BET analysis result of AC shows that it is a mesoporous material (average pore diameter 2.193 nm). Additionally, Au-loaded AC-SH could be substantially desorbed (>95% recovery) using a concentrated thiosulfate solution. Herein, an economical, simple, and easy-to-implement method for the effective recovery of Au(I) from thiosulfate solution is described, which is expected to advance the development and application of non-cyanide Au extraction technology.
研究领域:
环境科学
·
材料科学
·
冶金工程
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DOI
高影响因子
Acta Biomaterialia
·
2021
·
IF 8.947
Jing Cao,Yu Sun,Cong Zhang,Xue Wang,Yiqing Zeng,Tao Zhang,Pintong Huang
Sonodynamic therapy (SDT) represents a viable approach to overcoming the limited ability of photodynamic therapy to penetrate biological barriers. However, pancreatic tumors contain a hypoxic microenvironment that limits the efficacy of oxygen-dependent type II SDT, complicating efforts to develop reliable, stable, and hypoxia-tolerant sonosensitizer. Herein, a tablet-like TiO 2 /C nanocomposite with a metal-organic-framework (MOF)-derived carbon structure was designed and found to be hypoxia-tolerant and stable in response to repeated ultrasound irradiation, enabling the TiO 2 /C-mediated generation of large quantities of reactive oxygen species (ROS) and thereby achieving efficacious type I SDT. Importantly, this nanocomposite continued to generate ROS in response to repeated ultrasound irradiation, and was able to induce tumor cell apoptosis via SDT-induced DNA damage in vitro and in vivo . This TiO 2 /C nanocomposite also exhibited good biocompatibility and did not induce any apparent toxicity in vitro and in vivo . Together, these data highlight TiO 2 /C as a valuable nanocomposite capable of facilitating repeated type I SDT, making it a promising tool for the treatment of hypoxic solid pancreatic tumors. Statement of significance In this research, a tablet-like TiO 2 /C nanocomposite with a metal-organic-framework (MOF)-derived carbon structure was designed, which exhibited great stability upon repeated ultrasound irradiation, hypoxic-tolerant ability and good biocompatibility. After ultrasound irradiation, TiO 2 /C could efficiently generate reactive oxygen species in an oxygen-independent manner, which overcame the limitation of pure TiO 2 nanoparticles . Therefore, it was applied to repeated type I sonodynamic therapy of hypoxic pancreatic tumor.
研究领域:
纳米技术
·
癌症治疗
·
生物医学工程
·
材料科学
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DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）