APPLIED CATALYSIS B-ENVIRONMENTAL
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2026
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IF 19.7
Ximan Wang,Yanshu Chen,Dehui Bian,Sigen A,Wenyue Zhao,Yunfeng Wu,Siqi Bao,Yingchen Duan
Novel Yb-BiOI/Ce-MgAl-LDH S-scheme heterojunction boosts photo-Fenton degradation. • Substrate molecular orbitals govern the selective 1 O 2 -dominated degradation. • S-scheme heterojunction achieves 100% TC-HCl degradation within 20 min. • The system demonstrates excellent environmental adaptability and stability. • Photocatalytic mechanism elucidated via experiments and DFT calculations. Developing highly selective catalytic systems remains a grand challenge in advanced water remediation. A novel S-scheme Yb-BiOI/Ce-MgAl-LDH heterojunction was rationally designed to synergistically boost photo-Fenton degradation via targeted singlet oxygen ( 1 O 2 ) generation. Unambiguously validated by in situ XPS and density functional theory (DFT) calculations, the S-scheme charge-transfer pathway efficiently accelerated spatial carrier separation while preserving maximum redox potentials. Consequently, the composite rapidly degraded the parent tetracycline hydrochloride within 20 min and achieved a mineralization efficiency of 52.5%, exhibiting outstanding degradation performance. Crucially, mechanism studies and density functional theory analyses have demonstrated that this highly selective reaction process, driven primarily by 1 O 2 as the dominant reactive oxygen species, is essentially determined by the energy levels of the specific molecular orbitals of the substrate. Pathway elucidation, coupled with in silico predictions and empirical phytotoxicity bioassays, comprehensively confirmed the substantial reduction in intermediate ecotoxicity. Ultimately, the scientific value of this work lies in providing deep mechanistic insights into S-scheme-driven selective oxidation, offering a robust and sustainable paradigm for designing targeted detoxification systems in wastewater treatment. Download: Download high-res image (262KB) Download: Download full-size image
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VETERINARY MICROBIOLOGY
·
2026
·
IF 2.8
Leyu Hu,Lexi Gao,Xingwei Fu,Zesheng Rong,Yue Cheng,Yuhan Hou,Lu Han,Xin Ran,Guiwen Guan,Ting Zhou,Lingling Chang,Xiaomin Zhao,Qian Du,Yong Huang,Dewen Tong,Mingjun Zhu
PEDV infection induces intracellular iron accumulation in host cells. • Iron promotes CoV replication by enhancing Fe-S cluster-dependent RdRp activity. • TEMPOL suppresses CoV replication by disrupting viral Fe-S cluster integrity. • TEMPOL exhibits broad-spectrum anti-CoV activity in vitro and in vivo. • TEMPOL effectively counteracts iron-exacerbated viral pathogenesis in vivo. Coronaviruses (CoVs) can cause severe respiratory and enteric diseases, posing major threats to human health and the livestock industry. However, the host metabolic mechanisms underlying viral replication remain unclear. Using porcine epidemic diarrhea virus (PEDV) as the primary model, this study investigated the role of iron metabolism in CoV replication and its mechanisms. Our results showed that PEDV infection markedly induced intracellular iron accumulation, while exogenous iron supplementation enhanced viral replication and iron chelation suppressed it. Mechanistically, iron enhances viral replication by promoting the formation of iron-sulfur (Fe-S) clusters, essential cofactors for the viral RNA-dependent RNA polymerase (RdRp). Based on these findings, we further evaluated the antiviral activity of TEMPOL, a small molecule targeting viral Fe-S clusters. TEMPOL reduced RdRp activity and effectively inhibited PEDV replication. Moreover, TEMPOL exhibited broad-spectrum antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), infectious bronchitis virus (IBV), and porcine deltacoronavirus (PDCoV). Importantly, TEMPOL effectively reversed FAC-promoted viral pathogenesis, alleviating tissue lesions and clinical symptoms across multiple CoV animal models. Collectively, this study reveals a key role of iron metabolism in CoV replication and suggests that targeting viral Fe-S clusters may provide a novel strategy for anti-CoV therapy against diverse CoVs.
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高影响因子
Catalysts
·
2026
·Vol. 16
·期 4
·342
·
IF 4.5
Yang Deng,Shuhong Wu,Jun Zhu
Driven by the progress of sustainable development, environmental remediation and water treatment have become increasingly important. Photocatalysis, capable of degrading pollutants through light (especially visible light) irradiation, has received widespread research attention. Titanium dioxide(TiO2) is a promising photocatalyst, yet its practical use is limited by low visible-light utilization and rapid photogenerated charge recombination. Herein, an S-scheme TiO2-WO3(Tungsten trioxide) heterojunction was successfully fabricated; the difference in Fermi levels induces a built-in electric field directed from TiO2to WO3, which thus constructs the S-scheme heterojunction. The as-prepared heterojunction exhibits a markedly enhanced transient photocurrent density, with the carrier lifetime prolonged from 2.69 ns to 41.61 ns. Under visible-light irradiation, the heterojunction achieves a methylene blue (MB) removal efficiency of over 95% within 90 min, and its pseudo-first-order kinetic rate constantkreaches 0.032 min−1, which is approximately 16 times that of pure TiO2. Radical trapping experiments confirm that the dominant active species responsible for the catalytic process are photogenerated holes and the hydroxyl radicals derived therefrom.
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CERAMICS INTERNATIONAL
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2026
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IF 6
Cunxin Wei,Yiheng Cao,Haitao Li,Xinyue Jiang,Tianyi Zhang,Bin Zhang,Huiping Qi,Yan Liu
A CdS-WO 3 S-scheme heterojunction material modified by CQDs was constructed through simple methods, which effectively increases the photocatalytic degradation rate of single CdS. In the composite material, CdS acts as a reducing photocatalyst (RP) and WO 3 acts as an oxidizing photocatalyst (OP), forming an S-scheme heterojunction. In order to solve the photocorrosion problem of CdS, carbon quantum dots (CQDs) were loaded onto CdS. The CQDs possess a high work function, enabling them to facilitate electron transfer, enhance the migration of photogenerated carriers, and suppress electron-hole pair recombination, thus improving photocatalytic performance. The characterizations of XRD, TEM, element mapping, and XPS confirmed the successful synthesis of the CQDs-CdS-WO 3 composite. The material not only exhibited a photocatalytic degradation efficiency of 89.7% and 58.8% towards norfloxacin and tetracycline, respectively, but also revealed a certain degradation capability toward methylene blue and methyl orange. The primary active substances relevant in this degradation process are h + , 1 O 2 , H 2 O 2 , • O 2 − , and • OH. After multiple cyclic experiments, the material still maintains stable crystalline structure and degradation activity. Therefore, the successful preparation of this composite material provides a new method for photocatalytic decomposition of antibiotics and organic dyes.
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JOURNAL OF MEMBRANE SCIENCE
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2026
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IF 8.8
Hao Chen,Haoji Lao,Libin Wang,Qin Wang,Guyu Xiao
Coating the charged aromatic polymers on ultrafiltration membranes is a feasible strategy to fabricate antifouling nanofiltration (NF) membranes. However, these NF membranes haven’t achieved high rejection and also are very limited because such polymers should be soluble in commonly polar solvents. Sulfonated poly(arylene ether ketone)s (sPAEKs) generally show poor solubility in commonly polar solvents due to their rigid polymer backbones, thus they could not be employed as the coating materials of NF membranes at present. Herein, the soluble sPAEKs in commonly polar solvents are synthesized by attaching methyl side groups to their polymer backbones. Accordingly, these sPAEKs could be coated on ultrafiltration membranes to prepare the antifouling NF membranes. Moreover, the Lewis acid-base interactions between the carbonyl and cation of the sPAEKs coating layer could improve rejection. Besides, their hydrophilic sPAEKs coating layer is favorable for improving permeability. Therefore, the sPAEKs coating layer endows the as-made membrane with excellent nanofiltration performances, such as an antibiotic rejection of 98%, a flux of 31.8 LMH/bar, an antibiotic/NaCl selectivity of 43.6, and a flux recovery rate of 98% for the foulant of bovine serum albumin. It still showed excellent resistance to chlorine oxidation because of the aromatic backbone of the sPAEKs coating layer. This fabrication strategy paves a facile way to achieve high performance NF membranes.
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ENVIRONMENTAL SCIENCE & TECHNOLOGY
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2025
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IF 11.3
Yanwei Wang,Jiahui Zhao,Yong Chen,Xuesong Liu,Tengfei Xu,Mingliang Fang
Chronic bisphenol exposure is a recognized disruptor of liver function, and although ferroptosis has been implicated, the underlying molecular mechanisms remain poorly defined. Here, integrative chemical proteomics and untargeted metabolomics were used to elucidate mechanisms of ferroptosis induced by bisphenol A (BPA) and bisphenol S (BPS) in hepatic cells. BPA elicited a pronounced ferroptotic phenotype, whereas BPS elicited a moderate phenotype in hepatocytes. Glutathione peroxidase 4 (GPX4) and pyruvate kinase M2 isoform (PKM2) were identified as critical targets, respectively. Validation through cellular thermal shift assay (CETSA), surface plasmon resonance (SPR), and molecular docking confirmed that BPA specifically binds to GPX4 (KD = 37.6 μM), while BPS exhibits moderate affinity for PKM2 (KD = 14.4 μM). Functional rescue experiments demonstrated that GPX4 overexpression effectively reversed BPA-induced ferroptosis and partially alleviated BPS-induced effects, whereas PKM2 overexpression specifically mitigated BPS-triggered cytotoxicity. Mechanistically, BPA inhibited GPX4 activity, impairing lipid peroxide detoxification and triggering ferroptosis; BPS suppressed PKM2, promoting glucose flux toward the methylglyoxal (MGO) pathway, depleting glutathione, and activating oxidative stress, thereby inducing ferroptosis indirectly. This study clarifies bisphenol-induced ferroptosis via target heterogeneity, providing mechanistic insights that may inform future safety evaluations.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2026
·
IF 19.9
Sibo Wang,Yue Zhang,Wanlong Wu,Quanwei Jiang,Hua-Yu Shi,Xiaoqi Sun
Aqueous Zn─S batteries are promising energy storage systems with high theoretical capacity and low cost. However, the direct conversion between S and ZnS at the cathode suffers extremely sluggish reaction kinetics, which further decay rapidly upon the increase of current density and active material loading. Facing these challenges, we herein present a bi-directional redox mediator strategy and identify a self-adjusted Cu-based candidate. It possesses two redox couples whose potentials are on either side of the thermodynamic redox potential of S/ZnS reaction while between its kinetic oxidation and reduction potentials. These alignments enable the bi-directional mediator to catalyze the charge and discharge processes using either redox couple, respectively. As a result, the sulfur cathode reaches a high capacity of 1629 mAh g −1 at 0.1 A g −1 . It also maintains 880 mAh g −1 after 500 cycles at 1 A g −1 , superior to rapid decay to 148 mAh g −1 after only 28 cycles with the mediator free cathode. Furthermore, with a high sulfur loading of 7.3 mg cm −2 and lean electrolyte of 7 µL mg S −1 , the Zn─S battery achieves a high areal capacity over 10 mAh cm −2 .
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高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Zhanwei Xu,Hang Niu,Ying Zhang,Siyu Chen,Wenyang Li,Jiayin Li,Liang Li,Xuetao Shen
The shuttle behavior and sluggish conversion kinetics of polysulfides (LiPSs) significantly hinder sulfur utilization and cycle stability of lithium–sulfur (Li–S) batteries. Herein, iron hexadecafluorophthalocyanine (FePcF16) nanoparticles were in situ tailored on oxidized apple pomace carbon (OAPC) with a 3D porous structure to construct a high-performance FePcF16/OAPC sulfur host for advanced Li–S batteries. The designed FePcF16 nanoparticles have strong adsorption and catalytic conversion capabilities, which can reduce the redox reaction energy barrier, accelerate the conversion rate, and inhibit the LiPS shuttle. Meanwhile, the unique porous structure of OAPC effectively realizes the sulfur accommodation and rapid transport of substances. The average capacities of batteries with FePcF16/OAPC were 926.83, 847.11, and 782.63 mA h/g after 500 cycles at 1, 2, and 3C current densities, with capacity decay rates of only 0.020%, 0.031%, and 0.043% per cycle, respectively. Furthermore, it delivers favorable cycling stability at a sulfur load of 4.32 mg/cm2.
研究领域:
储能
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材料科学
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电化学
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纳米材料
·
电池技术
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ACS Applied Materials & Interfaces
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2017
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IF 7.504
Si-Yu Liu,Chao-Ying Fan,Yan-Hong Shi,Han-Chi Wang,Xing-Long Wu,Jing-Ping Zhang
A three-layered cathode structure was designed to minimize the shuttle effect of polysulfides and improve active material utilization. The three-layered configuration was fabricated by directly dropping pure sulfur composite slurry into multifunctional dual-barrier layers consisting of a self-standing TiO2/C interlayer and a very thin acetylene black layer (0.35 mg cm–2). In consequence, a decent discharge capacity of 963 mA h g–1 was acquired after 100 cycles at 0.1 C. With cycling at 0.1, 0.2, 0.5, 1, and 2 C, the cells displayed excellent reversible capacities of 1203, 1145, 1035, 934, and 820 mA h g–1, respectively. Furthermore, the cells still delivered a satisfactory discharge capacity of 799 mA h g–1 after 300 cycles at 0.5 C. The light mass of the three-layered configuration guarantees that the energy density is effectively improved, considering the overall mass of the cathode. The energy density (603 W h kg–1 after 100 cycles) was at a high level compared with those of the reported ones. Therefore, it is believed that the synergistic design for the three-layered cathode structure, which combines the mass-produced layer-by-layer structure, provides a novel protocol to the practical application of lithium–sulfur batteries.
研究领域:
储能技术
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材料科学
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电化学
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高影响因子
ELECTROCHIMICA ACTA
·
2023
·
IF 6.6
Xianwei Geng,Chenguang Liu,Chun Zhao,Zhongjie Jiang,Eng Gee Lim,Yongjie Wang,Ivona Mitrovic,Li Yang,Pengfei Song
As a novel two-dimensional (2D) layered material, Ti 3 C 2 T x MXene has excellent electronic conductivity and strong polysulfides adsorption. Its potential for Li-S batteries has been well recoginised since it can compensate conductivity of sulfur and improve cycling stability simultaneously. However, like other 2D materials , the stacking feature of the MXene nanosheet greatly limits its advantages and applications. Herein, a sulfydryl-modified MXene - sulfur cathode is synthesized via simple hydrothermal and copolymerization reactions. Compared to the conventional physical absorption between MXene and polysulfide, it was found that a chemical modification of MXene offers a much robust structure with little stacking on MXene. During the discharge process high-order Li 2 S 4 intermediates were first formed but consumed immediately. The remaining polysulfides are only short chains of Li 2 S, Li 2 S 2 and Li 2 S 3 . This type of cathode can greatly suppress the “shuttle effect” by reducing the generation of soluble high-order polysulfides in the electrolyte, which is attributed to rapid capacity fading. As a result, the cathode achieves an excellent initial specific capacity of 1367 mAh·g −1 at 0.1 C. It also has a high first capacity of 880 mAh·g −1 and remains 715 mAh·g −1 after 500 cycles at 1 C, with a retention rate of 81.3%. Our work provides a new strategy for applying MXene in the Li-S battery field.
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Biomaterials Science
·
2022
·Vol. 11
·期 3
·894-907
·
IF 7.59
Yiran Wang,Mingxi Yang,Jiayi Zhang,Jingyan Ren,Ning Liu,Bin Liu,Laijin Lu,Bai Yang
Myocardial fibrosis (MF) is a critical pathological lesion in the progression of various acute and chronic cardiovascular diseases. However, there is still a lack of clinically effective drugs and treatments for MF therapies. Herein, for the first time, we developed fluorescent sulfur-doped carbonized polymer dots (S-CPDs) as new nano-antioxidants to reduce the cardiomyocyte damage caused by reactive oxygen species (ROS) in the early stage of fibrotic lesions. In vitro results suggested that the pre-protection of S-CPDs significantly increased the survival rate of H9c2 cells under severe oxidative stress, inhibited the isoproterenol (ISO)-induced hypertrophy of myocardial cells through improving the content of mitochondria related proteins and adenosine triphosphate (ATP) in cells. Moreover, S-CPD administration could effectively decrease cardiac hypertrophy and promote heart function in MF rat models. The rapid internalization, high biocompatibility and fluorescence imaging potential of S-CPDs revealed their promising application prospects in the diagnoses and treatments of cardiovascular diseases.
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高影响因子
Advanced Materials Interfaces
·
2022
·Vol. 10
·期 1
·2201730
·
IF 6.389
Zhijia Zhang,Yueqing Li,Xinjiao Cui,Sijia Guan,Long Tu,Haolin Tang,Zhenhua Li,Junsheng Li
Separator is a critical component of lithium–sulfur (Li–S) battery, and the property of separator influences the battery performance significantly. Cellulose-based separator is emerging as a promising alternative to the traditional polyolefin separator used in Li–S battery. Although the excellent battery performance of various cellulose-based separators is shown, a comprehensive understanding of the advantageous features of bacterial cellulose (BC)-based separator in Li–S battery still is lacking. In this work, models of BC separators with different thicknesses are prepared and compared with polypropylene separators in terms of their electrochemical performance. The results show that the BC separator exhibits favorable electrolyte affinity, improved lithium-ion transport, suppressed shuttling of soluble polysulfides, and inhibited the formation of lithium dendrites. The combination of these unique characters of BC separator endows it with excellent battery performance. These results provide insight into the use and design of functional cellulose-based separators in advanced secondary batteries.
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