BIOLOGICAL TRACE ELEMENT RESEARCH
·
2015
·Vol. 171
·期 1
·116-123
·
IF 1.748
Zhang Qiuyue,Cao Zheng,Sun Xudong,Zuang Cuicui,Huang Wanyue,Li Yanfei
Aluminum (Al) is the most abundant metal in the earth’s crust. Al accumulates in erythrocyte and causes toxicity on erythrocyte membrane. The dysfunction of erythrocyte membrane is a potential risk to hypertension. The high Al content in plasma was associated with hypertension. To investigate the effect of AlCl 3 on blood pressure and the function of erythrocyte membrane, the rats were intragastrically exposed to 0, 64(1/20 LD 50 ), 128(1/10 LD 50 ), and 256(1/5 LD 50 ) mg/kg body weight AlCl 3 in double distilled water for 120 days, respectively. Then, we determined the systolic and mean arterial blood pressures of rats, the osmotic fragility, the percentage of membrane proteins, the activities of Na + /K + -ATPase, Mg 2+ -ATPase, Ca 2+ -ATPase, catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GSH-pX), and malondialdehyde (MDA) content of the erythrocyte membrane in this experiment. The results showed that AlCl 3 elevated the systolic and mean arterial blood pressure of rats, increased the osmotic fragility, decreased the percentage of membrane protein, inhibited the activities of Na + /K + -ATPase, Mg 2+ -ATPase, Ca 2+ -ATPase, CAT, SOD and GSH-pX, and increased the MDA content of erythrocyte membrane. These results indicate that AlCl 3 may induce hypertension by disturbing the function of erythrocyte membrane.
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE
·
2015
·Vol. 26
·期 2
·1-12
·
IF 2.587
Tian Jinhuan,Shen Si,Zhou Changren,Dang Xiangli,Jiao Yanpeng,Li Lihua,Ding Shan,Li Hong
Implant-associated infection is one of the biggest problems in orthopedic surgery. Antimicrobial peptides (AMPs) are well-known components of the innate immunity and less susceptible to the development of pathogen resistance compared to conventional antibiotics. Magnesium alloys as potential biodegradable bone implants have been received much attention in biomaterials field. This study investigated the deposition of calcium phosphate (CaP) coatings and loading of AMPs on the magnesium alloy surface by a biomimetic method. Scanning electron microscope (SEM) results presented that a microporous and plate-like CaP coating was processed on the magnesium alloy surface. X-ray diffractometry (XRD) and Fourier transform infrared spectroscopy (FTIR) analysis showed the main component of coating was hydroxyapatite (HA). Degradation assay in vitro showed that the HA coating deposited onto the magnesium alloy was corroded more slowly than the bare one. The amount of AMP loaded in the HA coating was 11.16 ± 1.99 μg/cm 2 . The AMP loaded onto HA coatings had slow release for 7 days. The AMP-loaded coating showed antimicrobial activity against Staphylococcus aureus . Its bacterial inhibition rate exceeded 50 % after 4 days and the antibacterial effect was sustained for 7 days. The coated magnesium alloys loaded with AMP could improve rat bone marrow mesenchymal stem cells (rBMMSCs) proliferation. Furthermore, it could also promote alkaline phosphatase (ALP) activity of rBMMSCs. Both radiographic evaluation and histopathology analysis demonstrated that implantation of the coated magnesium alloy into the rabbit femoral condyle had promoted bone repair and showed anti-inflammatory effect. The results showed that the AMP loaded onto HA coatings on the magnesium alloy surface could be considered an ideal orthopedic implant against S. aureus infection.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2014
·Vol. 49
·期 14
·5141-5150
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IF 2.305
Zhuo Longhai,Kou Kaichang,Wang Yiqun,Yao Pan,Wu Guanglei
We report the design and synthesis of a novel pyridine-containing triamine monomer, 2,6-bis(4-aminophenyl)-4-(4-aminophenoxy)pyridine (BAAP), through combining the nucleophilic aromatic substitution with modified Chichibabin reaction and hydrazine hydrate reduction. Based on it, a novel three-step route was applied in order to obtain a series of new polyimides, containing phthalimide as pendent group and pyridine moieties in main chains. The three-step route consisted of terminating the triamine by incorporating phthalic amic acid as pendant, ring-opening polymerization to form poly(amic acid)s and further chemical imidization to acquire polyimides. Nuclear Magnetic Resonance Spectroscopy ( 1 H-NMR) was used for chemical structural characterization, and the results indicated the various forms of BAAP and branched structure units in the obtained polyimides. The morphology structures of the polyimides were evaluated by X-ray diffraction patterns, and the d -spacing values were found in the range of 4.14–4.65 Ǻ. Most of the resulting polyimides were soluble in polar aprotic solvents, such as NMP, DMF, DMAc, DMSO, and so on. Meanwhile, the polyimides exhibited excellent thermal stability, with the decomposition temperature at 5 and 10 % weight loss temperatures in the ranges of 399.1–461.1 °C and 481.1–566.9 °C, respectively. The polyimides, based on 6FDA, possessed the best comprehensive thermally stable and soluble performance.
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高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2014
·Vol. 301
·期 1
·257-262
·
IF 1.415
Zha Zhongyong,Wang Dingna,Hong Wei,Liu Li,Zhou Sai,Feng Xiaojie,Qin Bing,Wang Jianmei,Yang Yi,Du Liang,Zhang Dong,Fang Zhendong,Xia Chuanqin
This study aimed at influence of europium speciation on its accumulation in Brassica napus (CK) and over-expressing BnTR1 lines (OE), and the kinetics of Eu uptake were investigated. These results indicated that the uptake in the roots of OE was higher than that of CK at high concentrations of europium and even the enrichment in the roots of OE was as high as 20,000 mg/kg at 328.9 μΜ Eu, this suggested that OE might have better resistance to uranium than CK. The time kinetics in plants showed that there had the similar trend between CK and OE. The formation of Eu 3+ at pH 5 in deionized water was beneficial to plants enrichment Eu and carbonate could reduce the adsorption of Eu in two group and phosphate almost completely impress the adsorption of Eu in two group, but citric acid could enhance europium root-to-shoot translocation in two group. These results would help understanding the mechanism of Eu uptake in Brassica napus (CK) and over-expressing BnTR1 lines (OE), therefore properly developing efficient europium/americium phytoremediation.
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高影响因子
JOURNAL OF NANOPARTICLE RESEARCH
·
2014
·Vol. 16
·期 5
·1-12
·
IF 2.278
Lv Shaonan,Zhao Meiqin,Cheng Changjing,Zhao Zhigang
β-Cyclodextrin (β-CD) polymer
brushes decorated magnetic Fe 3 O 4 colloidal nanocrystal clusters (Fe 3 O 4 @PG-CD) were fabricated by a combination of surface-initiated atom transfer radical polymerization on the surface of Br-anchored Fe 3 O 4 colloidal nanocrystal clusters (Fe 3 O 4 –Br) and ring-opening reaction of epoxy groups. The resulted Fe 3 O 4 @PG-CD hybrid nanoparticles were characterized by several methods including Fourier transform infrared, transmission electron microscope, dynamic light scattering instrument, X-ray diffraction, thermogravimetric analysis, and vibrating sample magnetometer. Moreover, the potential of as-synthesized Fe 3 O 4 @PG-CD as a carrier of hydrophobic anticancer drug 5-fluorouracil (5-FU) was also investigated. The results showed that the prepared Fe 3 O 4 @PG-CD have core/shell structure and high saturated magnetism. 5-FU could be loaded into the Fe 3 O 4 @PG-CD via the formation of β-CD/5-FU inclusion complex. Furthermore, the Fe 3 O 4 @PG-CD displayed a high loading capacity and pH-dependent release behavior for 5-FU. The release behavior demonstrated a simple Fickian diffusion in the acidic environment (pH 2.0 and 4.0) but neither non-Fickian nor anomalous when neutral. The results reveal that this nanosystem seems to be a very promising vehicle for the hydrophobic drugs for pH-dependent controlled release.
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高影响因子
WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY
·
2013
·Vol. 30
·期 4
·1251-1260
·
IF 1.262
Zhou Gang,Shi Qing-shan,Ouyang You-sheng,Chen Yi-ben
Isothiazolones are used as preservatives in various modern industrial products. Although microorganisms that exhibit resistance towards these biocides have been identified, the underlying resistance mechanisms are still unclear. Therefore, we investigated the resistance properties of the following Burkholderia cepacia strains to Kathon (a representative of isothiazolones): a wild-type (WT) strain; a laboratory resistance strain (BC-IR) induced from WT; and an isolated strain (BC-327) screened from industrial contamination samples. The bacterial cell structure was disrupted by 50 μg ml −1 Kathon treatment. BC-IR and BC-327 did not display resistance in the presence of 1 ml L −1 Tween 80, 1 ml L −1 Triton X-100, 0.1 % sodium dodecyl sulfate or 1 mmol L −1 EDTA-2Na. Additionally, BC-IR and BC-327 exhibited lower relative conductivity from 10 to 180 min. The types as well as the levels of outer-membrane proteins (OMPs) were altered among WT, BC-IR and BC-327. Finally, the two Kathon-resistance strains BC-IR and BC-327 presented higher resistance capacity to H 2 O 2 . We measured the levels of peroxide-sensor genes and observed that the transcriptional activator oxyR , superoxide dismutase sod1 , sod2 , catalase cat1 and cat3 were all up-regulated under oxidative conditions for all strains. Taken together, OMPs and peroxide-sensor genes in B. cepacia contributed to isothiazolone resistance; However, the laboratory strain BC-IR exhibited a different resistance mechanism and properties compared to the isolated strain BC-327.
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高影响因子
IRANIAN POLYMER JOURNAL
·
2013
·Vol. 23
·期 1
·47-52
·
IF 1.053
Gan Linhuo,Zhou Mingsong,Yang Dongjie,Qiu Xueqing
Carboxymethylated lignin (CML), a water-soluble lignin derivative with more carboxylic groups introduced by chemical modification, can be used as dispersant in industry. In this paper, using the methods of zeta potential measurement, X-ray photoelectron spectroscopy and UV spectroscopy, natural graphite (NG) and high-purity graphite (HPG) were selected to investigate the adsorption characteristics of CML at the hydrophobic solid/water interface. The adsorption isotherm of CML on HPG was more suitable for the Langmuir model than the Freundlich model, whereas the opposite result was obtained for the adsorption of CML on NG. Moreover, the amounts adsorbed of CML on HPG increased with higher ionic strength and lowering solution pH. However, the uptake of CML on NG increased dramatically with adding NaCl under acidic condition, while the ionic strength had no obvious influence on the adsorption under neutral condition. With increasing solution pH, the amounts of CML adsorbed on NG were dropped under acidic condition followed by increases under alkaline condition. It is suggested that the interactions between CML and the minor metallic impurities on NG surface probably contribute considerably to the differences between adsorption behaviors of CML on NG and HPG in varying solution conditions. Moreover, the results showed that the adsorption mechanism of CML at graphite/water interface could be described by Lennard-Jones potential.
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高影响因子
CHROMATOGRAPHIA
·
2013
·Vol. 76
·期 23
·1569-1576
·
IF 1.437
Cheng Xiao-Dong,Peng Xi-Tian,Yu Qiong-Wei,Yuan Bi-Feng,Feng Yu-Qi
A new stationary phase which contains both negatively charged phosphate groups and positively charged amino groups was successfully synthesized by modification of amino-functionalized silica particles with trichlorophosphine oxide (POCl 3 ) for hydrophilic interaction chromatography (HILIC). The composition of the surface grafts was determined by Fourier transform infrared spectroscopy and elemental analysis. Various parameters, such as column temperature, water content, pH values and ionic strength of the mobile phase were investigated to study the retention mechanism. The results demonstrated that the stationary phase involved a complex retention process including surface adsorption, partitioning and electrostatic interactions. Under optimized conditions, the separation of nucleobases and nucleosides, water-soluble vitamins, organic acids on the novel stationary phase could be achieved in the HILIC mode.
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高影响因子
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
·
2013
·Vol. 68
·期 1
·54-59
·
IF 1.66
Li Jie,Chen LianXi,Li Xi,Zhang ZhongMing,Jiao CaiBin
A new class of poly(vinyl acetate) (PVAc)/silica nanocomposite particles was successfully prepared in aqueous solution through a facile synthetic process. First, vinyl functionalized silica nanoparticles (VFSs) were synthesized using one-step method in aqueous emulsion, and then the vinyl groups located on the surface of VFSs were used to induced in situ polymerization of vinyl acetate. Scanning electron microscopy (SEM) images showed that VFSs and PVAc/silica nanocomposite particles all revealed highly monodispersed and uniform spheres. Especially, PVAc/silica nanocomposite particles obtained from transmission electron microscopy images presented an obvious core–shell structure, and the thickness of PVAc shell grafting on the surface of VFSs core was about 17 nm. In addition, the influence of the hydrolyzed and condensed time of vinyl triethoxysilane on the size and size distribution of VFSs was also investigated. The results of dynamic light scattering and SEM analysis indicated that the size and size distribution of VFSs decreased gradually with the extension of the reaction time from 6 to 48 h. Moreover, the structures and thermal properties of the samples were characterized via FT-IR and heat-flow DSC–TG.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2015
·Vol. 26
·期 12
·9941-9948
·
IF 1.569
Zhang Rong,Lu Yi,Wei Ling,Fang Zhenggang,Lu Chunhua,Ni Yaru,Xu Zhongzi,Tao Shunyan,Li Peiwen
Double perovskite oxides Gd 0.8 Ca 0.2 BaCo 2 O 5+δ have been successfully prepared by EDTA-citrate complexation process. The prepared samples were characterized by means of thermogravimetry–differential analysis, X-ray diffraction, Fourier transform infrared spectroscopy techniques. These analyses suggested that pure Gd 0.8 Ca 0.2 BaCo 2 O 5+δ phase could be formed when the pH value was maintained above three and calcination temperature was higher than 850 °C. The conductivity properties analyzed by means of four probes method, scanning electron microscopy and X-ray photoelectron spectroscopy indicated an improvement in conductivity with a high value of nearly 1200 S/cm, which was due to an increase in the number of small polaron hopping conduction units, Co 3+ –O–Co 4+ . Interestingly, the Gd 0.8 Ca 0.2 BaCo 2 O 5+δ samples exhibited a semiconducting behavior through a wide range of temperature below 100 °C and a metallic behavior at 100–500 °C, thereby demonstrating that Gd 0.8 Ca 0.2 BaCo 2 O 5+δ could meet the requirements of a smart material.
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2015
·Vol. 26
·期 7
·5071-5077
·
IF 1.569
Li Anli,Li Pengwei,Hu Jie,Zhang Wendong
Single crystal Cu 2 O materials with morphologies of cube, truncated cube, truncated octahedron, octahedron etc. have been synthesized by a facile glucose reduction method. Polyvinylpyrrolidone concentration dependent, crystal-facet-controllable growth mechanism of the synthesized Cu 2 O crystals has been proposed in the article. The photocatalytic test results show that the octahedral Cu 2 O crystals with dominant {111} planes have super photocatalytic activity than the cubic ones packaged by {100} surfaces, which could be explained by that the polar, highly active {111} facets with unsaturated “Cu” have more excellent activity on the methyl orange dye degradation. This article will contribute to promote the morphology construction and crystal-dependent catalytic properties of metal oxide semiconductor materials.
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高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2015
·Vol. 307
·期 1
·269-276
·
IF 1.034
Luo Bai-Cheng,Yuan Li-Yong,Chai Zhi-Fang,Shi Wei-Qun,Tang Quan
Metal–organic frameworks (MOFs) UiO-66 and its amine derivative (UiO-66-NH 2 ) with high surface area and unprecedented chemical stability were synthesized and first explored for U(VI) capture from aqueous solutions. At pH 5.5, U(VI) sorption reach equilibrium in ca. 4 h and the maximum sorption capacity is more than 100 mg g −1 . Moreover, they show desirable selectivity towards U(VI) over a range of competing metal ions. Sorption results demonstrate that introduction of amino groups into MOFs does not enhance U(VI) sorption, probably result from the lower activity of aromatic amines, decrease of surface area and formation of intermolecular hydrogen bonds.
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