RESEARCH ON CHEMICAL INTERMEDIATES
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2021
·Vol. 47
·期 5
·1775-1787
·
IF 2.914
Chen Rong,Wu Songshuai,Meng Chuangang
A facile green synthesis of platinum nanoparticles (PtNPs) using chlorogenic acid (CGA) as a reducing agent and stabilizing agent has been reported here for the first time to the knowledge of the authors. Well-dispersed PtNPs are synthesized in spherical shapes and are tuned in size by simply changing the molar ratio of H 2 PtCl 6 to CGA, with the same salt, temperature and solvent. The average sizes of the particles were 16.9 ± 4.7, 13.3 ± 4.0, 10.8 ± 3.4, and 7.5 ± 2.3 nm, respectively, corresponding to molar ratios of the initial H 2 PtCl 6 /CGA of 1:1, 1:2, 1:3 and 1:4 and decreased with an increase in CGA concentration. Transmission electron microscope; energy-dispersive spectrometer; UV–visible absorption spectra (UV–Vis); and Fourier transmission infrared spectra were used to characterize the PtNPs. Additionally, the advantage of CGA for possible synergistic biological activity was studied through the in vitro antioxidant activity of PtNPs by CGA for capture of free radicals. Our results indicate that CGA is an excellent reducing and stabilizing agent in green synthesis of PtNPs, and these size-tunable PtNPs can provide potential applications in the field of biomedicines. Graphic abstract
研究领域:
纳米医学
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材料科学
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生物化学
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2021
·Vol. 28
·期 21
·27398-27410
·
IF 4.223
Chen Aixia,Pang Jiaju,Wei Xiao,Chen Bei,Xie Yaping
This work explored the use of porous carbon (PC) materials converted from waste lignin as raw materials for the removal of chloramphenicol (CAP) in water. The PC with controllable pores was prepared through a facile, cost-effective one-step method. The physical and chemical properties of the material were characterized by BET, SEM, FT-IR, and XRD, and the best conditions for preparation were selected based on the results of adsorption experiments. The PC, which was prepared at reaction temperature of 800 °C and the K 2 CO 3 /sodium lignosulfonate mass ratio of 4, namely PC-800-4, had a high specific surface area (1305.5 m 2 g −1 ) and pore volume (0.758 cm 3 g −1 ). At a lower initial concentration of CAP ( C 0 = 120 mg L −1 ), the maximum adsorption capacity of this adsorbent was 534.0 mg g −1 at 303 K. In addition, PC-800-4 maintained good adsorption performance in a wide pH range and strongly resisted the interference of ions and humic acid. The results showed that the adsorption removal CAP was based on physical adsorption and chemical adsorption as a process supplement. The advantages of wide sources, high efficiency and speed, wide application, and rich oxygen-containing functional groups made the adsorbent have great application potential for removal chloramphenicol from water.
研究领域:
环境科学
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材料科学
✓ 已验证
DOI
高影响因子
MATERIALS SCIENCE FORUM
·
2021
·
IF 0
Sha Chen,Jing Hua Gong,Jing Hong Ma
Helix is a sophisticated structure in nature and has many unique functions which makes it possible to store more information and energy, even receive more sensitive signals. Besides, as an effective method for preparing hydrogel fibers, microfluidic spinning has achieved unprecedented development in the past decade. However, hydrogel fiber with helical structure has began to be studied only in recent years. In this paper, the helical hydrogel fibers were prepared by the microfluidic spinning method. The microfluidic chip was assembled by PDMS connector, collection tube, inner and outer channels. Sodium alginate (SA) and calcium chloride were used as the core fluid and sheath fluid, respectively. By designing and adjusting the length of the chip, changing the concentration of SA and the ratio of two flow rates (inner flow rate/outer flow rate), a continuous and uniform helical hydrogel fiber was prepared. The relationships between the diameter of the fiber, the pitch of the helix and the concentration of SA, the ratio of two flow rates were discussed. The results showed that the diameter of the fiber was mainly affected by the core fluid. Within a certain range, as the concentration of SA increased, the diameter of the fiber increased. Besides, the pitch of the helix was greatly affected by the flow rate of sheath fluid. As the velocity of the sheath fluid increased, the pitch of the fiber increased. Such helical fiber could be used in micro sensors when added some conductive materials or crosslinked with some temperature responsive polymers such as N-isopropylacrylamide.
研究领域:
材料科学
·
生物医学工程
✓ 已验证
DOI
EXPERIMENTAL BIOLOGY AND MEDICINE
·
2024
·
IF 2.8
Run Ma,Na Xie,Yuanhui Shu,Yafeng Wu,Ping He,Yining Xiang,Yan Zhou,Yuping Wang
Liver fibrosis has become a serious public health problem that can develop into liver cirrhosis and hepatocellular carcinoma and even lead to death. Cannabidiol (CBD), which is an abundant nonpsychoactive component in the cannabis plant, exerts cytoprotective effects in many diseases and under pathological conditions. In our previous studies, CBD significantly attenuated liver injury induced by chronic and binge alcohol in a mouse model and oxidative bursts in human neutrophils. However, the effects of CBD on liver fibrosis and the underlying mechanisms still need to be further explored. A mouse liver fibrosis model was induced by carbon tetrachloride (CCl 4 ) for 10 weeks and used to explore the protective properties of CBD and related molecular mechanisms. After the injection protocol, serum samples and livers were used for molecular biology, biochemical and pathological analyses. The results showed that CBD could effectively improve liver function and reduce liver damage and liver fibrosis progression in mice; the expression levels of transaminase and fibrotic markers were reduced, and histopathological characteristics were improved. Moreover, CBD inhibited the levels of inflammatory cytokines and reduced the protein expression levels of p-NF-κB, NF-κB, p-IκBα, p-p38 MAPK, and COX-2 but increased the expression level of PPAR-α. We found that CBD-mediated protection involves inhibiting NF-κB and activating PPAR-α. In conclusion, these results suggest that the hepatoprotective effects of CBD may be due to suppressing the inflammatory response in CCl 4 -induced mice and that the NF-κB and PPAR-α signaling pathways might be involved in this process.
研究领域:
药理学
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肝病学
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分子生物学
✓ 已验证
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Ying Pan,Congying Rao,Xiaolin Tan,Yun Ling,Ayushi Singh,Abhinav Kumar,Baohong Li,Jianqiang Liu
Rational designing of carbon-based adsorbent precursors is an important way to enhance adsorption performance. In this work, fascinating Co@C composites have been designed and fabricated using a new cobalt-seamed metal–organic nanocapsule (Co-MONC), which exhibits incredibly high adsorption capacity for chlorpromazine (CPZ) removal from aquatic environments. Benefiting from its interconnected micro- and mesoporous structures, well-dispersed and highly available Co adsorption active sites, the optimal Co@C-900 exhibits ultrahigh CPZ adsorption capacity (1039.53 mg g −1 ) and excellent recycling ability, outperforming the reported porous materials and commercial activated carbon. Moreover, the adsorption behaviors of CPZ for the composite have been comprehensively investigated and the plausible adsorption mechanism was proposed. Apart from this, the interaction mechanism between exposed Co adsorption active sites and CPZ have been suggested with the aid of density functional theory (DFT) calculations. The presented investigation demonstrated a facile and designable strategy for the fabrication of highly effectively adsorbents for organic contaminant removal.
研究领域:
环境科学
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材料科学
·
药物化学
✓ 已验证
DOI
高影响因子
CATALYSIS COMMUNICATIONS
·
2015
·
IF 3.699
Feng Ding,Sizhao Zhang,Xuegang Luo,Xiaoyan Lin
A novel S/BiOCl thermocatalyst in response to heat excitation was successfully synthesized by a one-step method and then added into polymeric matrix to give corresponding films. The results obtained show that the surfaces of as-prepared films with S/BiOCl were truly degraded via thermocatalytic reactions at ambient conditions. The average molecular weights of experimental films have fallen dramatically, comparing to the comparisons. In addition, the changes of chemical groups were simultaneously observed in the process. Thus this thermocatalytic process maybe a very fascinating route to come true the degradation of polymeric films with lower temperature triggered.
研究领域:
材料科学
·
高分子化学
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环境功能材料
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催化化学
·
纳米材料
✓ 已验证
DOI
高影响因子
Desalination and Water Treatment
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2024
·
IF 1
Ai Zhang,Yuye Shen,Xueyan Yin,Andere Clement Miruka,Yuyi Gu,Yanan Liu
The fate of glucocorticoids (GCs) in environment has been an increasing concern. In this study, performance of calcium peroxide (CaO 2 ) in removing GCs was investigated using clobetasol propionate (CP) as the representative compound. Critical treatment parameters (including CaO 2 dosage, initial pH, reaction time, and initial CP concentration) were optimized for CP removal by Response surface methodology (RSM) with a four-level Box-Behnken factorial design. A coefficient of determination (R 2 ) value (0.97), model F-value (32.18) and its low p-value (F < 0.0001) along with lower value of coefficient of variation (9.35%) indicated the fitness of the model. The results showed that CaO 2 treatment was effective in CP removal due to its coupled effects of oxidation and adsorption during CaO 2 treatment. At optimum CaO 2 dosage (3.43 g L –1 ), initial pH (7), reaction time (17.34 min), and initial CP concentration (0.03 mM), the model predicted 95.0% CP removal against the experimental value of 94.2 % CP removal. Water matrixes influenced CP removal during CaO 2 treatment in which HCO 3 – ions played an inhibitory role. The highest removal efficiency was obtained in underground water, followed by in secondary effluent, in tap water, and in surface water.
研究领域:
环境科学
·
药物代谢
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分析化学
·
污染控制技术
✓ 已验证
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2016
·
IF 3.299
Yajie Qian,Jing Zhang,Yalei Zhang,Jiabin Chen,Xuefei Zhou
In this study, a newly emerging oxidant nanoscale calcium peroxide (nCaO 2 ) was synthesized to degrade 2,4-dichlorophenol (2,4-DCP). nCaO 2 was prepared from nanoscale Ca(OH) 2 and H 2 O 2 and confirmed to be less than 150 nm in diameter and 62.23 m 2 · g −1 in specific surface area (SSA). For treating 2,4-DCP, the optimal ratio between Ca(OH) 2 and H 2 O 2 was 1:5. Compared with conventional CaO 2 , nCaO 2 was found to be more efficient for destructing 2,4-DCP. 2,4-DCP was completely degraded in 5 d by nCaO 2 while only 75.0% 2,4-DCP was destructed by conventional CaO 2 . The effects of solution pH and water matrix, including SO 4 2− , HCO 3 − and humic acid (HA) were examined. The reactive species in nCaO 2 system was investigated by photoluminescence (PL) technique and the quenching experiments. Results showed that hydroxyl radical (OH ) was the dominant reactive species for destructing 2,4-DCP. The major oxidation products identified in this study were 2-chlorophenol (2-CP), 4-chlorophenol (4-CP), phenol and benzoquinone (BQ). Our works gave an important insight into the use of nCaO 2 to degrade some organic contaminants which might provide some references for the application of nCaO 2 in chlorophenols contaminated groundwater remediation.
研究领域:
环境科学
·
化学
✓ 已验证
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2017
·
IF 3.648
Hongmei Zhang,Yanqing Wang,Haidan Zhu,Zhenghao Fei,Jian Cao
Triclocarban (TCC) is an antibacterial agent in antibacterial personal care products. Human serum albumin (HSA) is the transport protein with the ligand binding properties. The current study was undertaken to identify the binding mechanism of TCC with HSA by using biophysical methods . The fluorescence and UV–vis spectral results showed that the fluorescence quenching of HSA by TCC was static quenching by the formation of HSA-TCC complex. The binding constants were obtained by molecular modeling and fluorescence quenching, and the results indicated the existence of strong interaction between HSA and TCC with binding constant K b ~ 10 5 L/mol. TCC can enter into the binding pocket of domain II of HSA by mainly hydrophobic and hydrogen bonds forces. The conformations of TCC and HSA are all changed during the binding interaction of them. We hope that this work will provide some useful information for understanding the activity and mechanism of antibacterial agent with the transport protein.
研究领域:
生物化学
·
药理学
✓ 已验证
DOI
高影响因子
Journal of Applied Spectroscopy
·
2025
·
IF 1
Han Dan,Niu Xiaoxue,Wang Jing,Yan Zihong
Zr and Cl double-doped carbon dots (Zr/Cl-CDs) were prepared by a one-step hydrothermal method using citric acid, urea, and ZrCl 4 as precursors. Zr/Cl-CDs were characterized by ultra-violet-visible spectroscopy (UV-Vis), transmission electron microscopy, Fourier transform infrared spectroscopy, X-ray diffraction, and X-ray photoelectron spectroscopy (XPS). Experimental analysis revealed that the average size of Zr/Cl-CDs was 2–3 nm, while XPS analysis revealed the presence of C–Cl and Zr–O bonds. The fluorescence quantum yield of the final CDs was 17.5% at the excitation of 360 nm. In addition, Zr/Cl-CDs exhibited excellent performance in the detection of rutin with a concentration of 30–110 and 100–160 μmol/L, respectively. Linear correlation coefficients (R 2 ) were 0.9931 and 0.9962. The underlying mechanism was that rutin had an excellent quenching effect on the emission of the Zr/Cl-CDs as the fluorescence intensity exhibited a good linear relationship between rutin concentration and fluorescence intensity. These findings provide a new strategy for synthesizing double-doped CDs for rutin detection.
研究领域:
材料科学
·
分析化学
✓ 已验证
DOI
高影响因子
JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL
·
2015
·
IF 3.615
Jian Wang,Xue Wang,Xiaolong Liu,Junlin Zeng,Yangyang Guo,Tingyu Zhu
In this article, we present a detailed study combining the kinetic studies and in-situ FTIR experiments to investigate the oxidation behavior of chlorobenzene over V 2 O 5 /TiO 2 catalysts. The catalytic data show the 3–5 wt.% V 2 O 5 /TiO 2 catalysts are best fit for the oxidation of chlorobenzene. The calculated apparent reaction orders are about 0.6 and 0.2, respectively. The results of in-situ FTIR provided mechanism insights into the catalytic reaction, which supports the following proposal: (i) a nucleophilic substitution on V O species and (ii) attacking by surface oxygen through a electrophilic substitution, then (iii) followed by the cracking of ring structure, and further oxidation of the resulting species to form final products. The above results further suggest that the nucleophilic substitution process and surface reaction are kinetically significant steps for chlorobenzene oxidation, determining the overall rate of the reaction. Furthermore, 1,2-dichlorobenzene, 1,3-dichlorobenzene and 1,2,4-trichlorobenzene as additional reactants were tested together with chlorobenzene in binary mixtures to examine their competition reactions.
研究领域:
环境科学
·
催化化学
✓ 已验证
DOI
高影响因子
JOURNAL OF VINYL & ADDITIVE TECHNOLOGY
·
2021
·Vol. 28
·期 4
·689-695
·
IF 1.993
Hong-ying Chu,Hua-bei Li,Xiao-yan Sun,Yao-wang Zhang
The objective of this study is to synthesis biomass-based plasticizer epoxy p -phenylenedioleic acid ester (EPAE) using linoleic acid as raw materials via esterification and epoxidation. EPAE was used as main plasticizer of polyvinyl chloride (PVC) to replace diisobutyl phthalate (DIBP). The plasticizing effect of EPEA on the performance of PVC films was investigated. The results showed that epoxy groups were covalently bonded on branched chains of EPAE. EPAE play a plasticizing role by forming hydrogen bond between epoxy group and a-hydrogen on PVC. When the mass of EPAE was 0.8 g in 2 g PVC, Tg of flexible PVC reached 36.1°C, the elongation at break of flexible PVC was 321.12 ± 6.13%, while the tensile strength reached 19.45 ± 1.35%. The transmittance of DIBP-0.8 and EPAE-0.8 at 800 nm is nearly 70%, indicating relatively high homogeneous amorphous aggregation structures. EPAE showed marginal resistance to volatilization and solvent extraction. The mechanism behind the results was discussed.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）