Chemical Engineering Journal Advances
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2021
·
IF 0
Chao Liu,Cao Fang,Changsheng Shao,Xinxin Zheng,Hangbo Xu,Qing Huang
Currently, there is a huge demand for medical biomaterials aimed to improve antibacterial effect and promote wound healing. In this work, a facile and single-step approach of synthesizing silver nanoparticles (AgNPs) and reduced graphene oxide (rGO) composite material (namely, AgNPs@rGO) using high-voltage direct-current (DC) non-thermal plasma was proposed. Electron-beam (e-beam) from the DC-plasma discharge zone was implanted into the solution of AgNO 3 and graphene oxide (GO), leading to the reduction of both GO and silver ions. As a result, AgNPs were formed and distributed homogeneously on the reduced graphene sheets. This composite material exhibits excellent antibacterial performance, being able to kill both Gram-positive bacteria Staphylococcus aureus ( S. aureus ) and Gram-negative bacteria Escherichia coli ( E. coli ) effectively. Furthermore, this composite material was utilized to prepare wound-healing band-aids. The in vitro assay on mice confirmed the satisfactory curing effect. The cytotoxicity for bio-compatibility and the mechanism for sterilization were also examined and clarified. As such, this work puts forward a facile and new route of preparing antibacterial biomaterial and demonstrates its promising prospect in wound-healing application.
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BIOMACROMOLECULES
·
2015
·
IF 5.75
Menglin Wang,Jin Sun,Yinglei Zhai,He Lian,Cong Luo,Lin Li,Yuqian Du,Dong Zhang,Wenya Ding,Shuhong Qiu,Yuhai Liu,Longfa Kou,Xiangfei Han,Rongwu Xiang,Yongjun Wang,Zhonggui He
To improve the bioavailability of orally administered drugs, we synthesized a pH-sensitive polymer (poly(ethylene glycol)–poly(2-methyl-2-carboxyl-propylene carbonate)–vitamin E, mPEG–PCC–VE) attempting to integrate the advantages of enteric coating and P-glycoprotein (P-gp) inhibition. The aliphatic polycarbonate chain was functionalized with carboxyl groups and vitamin E via postpolymerization modification. Optimized by comparison and central composite design, mPEG113–PCC32–VE4 exhibited low critical micelle concentration of 1.7 × 10–6 mg/mL and high drug loading ability for tacrolimus (21.2% ± 2.7%, w/w). The pH-responsive profile was demonstrated by pH-dependent swelling and in vitro drug release. Less than 4.0% tacrolimus was released under simulated gastric fluid after 2.5 h, whereas an immediate release was observed under simulated intestinal fluid. The mPEG113–PCC32–VE4 micelles significantly increased the absorption of P-gp substrate tacrolimus in the whole intestine. The oral bioavailability of tacrolimus micelles was 6-fold higher than that of tacrolimus solution in rats. This enteric polymer therefore has the potential to become a useful nanoscale carrier for oral delivery of drugs.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2025
·
IF 3.9
Hao Liu,Shiyang Yan,Wei Wang,Xin Shi,Luming Yang,Haibin Gu
Electronic skin (e-skin), an emerging class of flexible integrated electronic devices, is designed to replicate the multifaceted functionalities of human skin, playing a critical role in the realms of wearable technology and healthcare monitoring. Despite their potential, the existing e-skins often fall short in achieving the robust mechanical strength, multifunctionality, and biocompatibility necessary for real applications. Durability and aesthetic appeal are also highly valued. This study introduced an innovative, ultratough, multifunctional transparent leather-based e-skin that can address these challenges. By employing the natural microstructure of tanned goatskin as a substrate, this work created this e-skin with an interpenetrating network structure containing a cross-linked copolymer of acrylic acid (AA) and hydroxypropyl acrylate (HPA) and integrated a variety of functional fillers, including Zr-CQDs (zirconium-doped carbon quantum dots) for conductivity, curcumin for antibacterial properties, and the eutectic solvent comprised of ethylene glycol and choline dihydrogen citrate for antifreezing and moisturizing capabilities. This e-skin exhibited remarkable mechanical properties with a tensile strength of 11.92 MPa and exceptional toughness of 5.26 MJ/m3, alongside 70% light transmission, showcasing its transparency. Its multimodal sensing capabilities enabled precise monitoring of diverse environmental stimuli, including strain, temperature, humidity, and bioelectrical signals, representing a significant advancement in wearable sensor technology. This work not only breathes new life into traditional leather materials for contemporary applications but also paves the way for sustainable and functional e-skin innovations, pushing the boundaries of wearable technology.
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Journal of Water Process Engineering
·
2020
·
IF 3.465
Wanhe Qi,Songming Zhu,Abubakar Shitu,Zhangying Ye,Dezhao Liu
Under Minamata Convention restrictions, mercury-free UV source was in need for ultraviolet disinfection in recirculating aquaculture systems (RAS). Ultraviolet emitting diodes (UV-LEDs) seemed a potential mercury-free UV source and had gained increasing attention in water disinfection. In this study, a mercury-free UVA-LED and low concentration peroxymonosulfate (PMS) combination was proposed for E. coli (CGMCC 1.3373) inactivation and real RAS wastewater disinfection. Results showed that UVA-LED and low concentration PMS combination enhanced E. coli inactivation over UVA-LED alone. A synergistic effect on E. coli inactivation with synergy factor of 58.7 % was found when combining UVA-LED irradiation with 1 mg/L PMS. Kinetic rate constant increased by up to 139 % by UVA-LED and 1 mg/L PMS combination, which implied the required UV fluence to 2-log E. coli inactivation was saved up to 42 %. Also, UVA-LED and 1 mg/L PMS combination showed disinfection potential for real RAS wastewater treatment. Mechanism study revealed that the Cl − , · OH and SO 4 ·- played important roles and · OH was dominant radical in saline solution by UVA-LED/PMS process compared to that in phosphate buffered solution(PBS). The E. coli inactivation was caused by UVA-LED irradiation and reactive species generated in UVA-LED/PMS system. Our study provided a potential strategy to introduce the mercury-free UV-LED into RAS and a better understanding of UVA-LED/PMS disinfection process.
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Journal of Integrative Neuroscience
·
2025
·Vol. 24
·期 7
·39656
·
IF 2.7
Guoying Dong,Yuxiao Liu,Huijun Liu,Chen Qiao,Xia Chen,Linxiao Wang
Background:Dyslipidemia during midlife represents a significant risk factor for neuropathological alterations associated with cognitive decline. Given the currently incurable nature of dementia, implementation of preventive strategies and early therapeutic interventions prior to disease progression are paramount. Emerging evidence suggests that hyperbaric oxygen (HBO) therapy exhibits neuroprotective properties in various neurological conditions. However, whether HBO treatment modulates lipid metabolism dysregulation and subsequent neurodegeneration remains unanswered. This investigation aimed to elucidate the therapeutic potential of HBO treatment in ameliorating cerebral dysfunction and metabolic perturbations using apolipoprotein E (ApoE)-deficient (ApoE-/-) mice.Methods:ApoE-/- mice received HBO treatment for 10 consecutive days, and then behavioral assessment tests were performed. Serum and brain tissue were collected to measure oxidative stress levels and inflammatory factors.Results:Compared with ApoE-/- group, cognitive declines was significantly reversed in mice of the ApoE-/-+HBO mice. The blood lipid profiles of ApoE-/- mice were also improved after HBO treatment, accompanied by a reduction in body weight. Moreover, HBO treatment was found to ameliorates neuronal injury and amyloid-β deposition in the hippocampus of ApoE-/- mice. Further studies have revealed that the benefits of HBO treatment occurred through the reduction of inflammatory factors and attenuation of oxidative stress.Conclusions:These findings indicate that HBO treatment effectively improves the intracerebral microenvironment of ApoE-/- mice, providing a novel regulatory mechanism of protection against dyslipidemia-associated brain deficits by HBO treatment.
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ACS Nano
·
2026
·
IF 17.3
Ruidong Xu,Tong Xu,Ming Li,Ganghua Li,Shukun Liu,Xinyang He,Bin Sun,Taotao Ai,Mingwei Tian
Flexible tactile-sensing devices are crucial for enhancing precision in wearable interaction electronics. However, traditional array-based sensing units encounter challenges in high environment robustness and spatial resolution. To address this limitation, we propose an array-free tactile-sensing E-textile that attains superior spatial resolution by exploiting non-faradaic junction effect between the E-textile and the human body. Upon finger contact, ions in the dermis redistribute directionally at the interface, creating a purely capacitive coupled nonfaradaic junction behavior that rapidly generates tactile-sensing signals (<40 ms). These signals demonstrate continuous, linearly graded, and complementary characteristics that enable accurate touch coordinate localization, allowing the E-textile to trace tactile trajectories (e.g., handwriting) at superior resolution without auxiliary integrated circuitry. Notably, the E-textile exhibits excellent robust performance under harsh conditions like extreme temperature (−30–80 °C, with error <0.0017%), mechanical damage, and cyclic washing (>50,000 cycle). Interestingly, this sensing approach can be extended to various mediums such as paper, wood, and water, showcasing its versatility for interactive applications. With its high spatial resolution, durability, and multimodal compatibility, the proposed E-textile offers a promising platform for next-generation human–machine interfaces.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Fangjie Liu,Zaifu Gong,HaiZhao Li,Wuhui Li,Yuliang Liu,Qingjie Wang
Proposes a functional modularization strategy to fabricate BZCY-GDC-LCO electrodes. • Exhibits low polarization resistance (0.141 Ω·cm 2 ) with 216 h stable operation. • Single cell delivers 0.757 W·cm −2 (FC) and 1.182 A·cm −2 at 1.3 V (EC) at 650 °C. Efficient triple-conduction (H + /O 2− /e − ) is vital for high-performance reversible protonic ceramic cells (R-PCCs), yet the underlying transport mechanisms and their specific impacts on electrode kinetics remain elusive. In this work, we employ a “functional modularization” strategy to engineer a BaZr 0.1 Ce 0.7 Y 0.2 O 3−δ -Gd 0.1 Ce 0.9 O 1.95 -LaCoO 3 (BZCY-GDC-LCO) triple-phase composite air electrode using commercially available precursors. The synergistic effects and individual roles of the conducting species in optimizing electrochemical kinetics were systematically investigated. The optimized BZCY-GDC-LCO electrode (1:1:1 mass ratio) exhibits excellent chemical compatibility, high oxygen vacancy concentration, and a well-distributed triple-phase boundary. Consequently, it achieves a low polarization resistance of 0.141 Ω·cm 2 at 650 °C and demonstrates robust long-term stability over 216 h of operation. Single-cell tests deliver a peak power density of 0.757 W·cm −2 in fuel cell mode and a current density of 1.182 A·cm −2 at 1.3 V in electrolysis mode at 650 °C. Kinetic analysis reveals oxygen adsorption/dissociation as the rate-determining step, while excessive steam partial pressure inhibits oxygen transport via surface site passivation. This work provides a scalable design strategy for high-performance R-PCC air electrodes, demonstrating that superior performance and favorable techno-economic feasibility can be achieved using conventional materials. Download: Download high-res image (166KB) Download: Download full-size image
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Algal Research-Biomass Biofuels and Bioproducts
·
2026
·
IF 5
Jikang Sui,Jinku Zhang,Xiangning Lu,Kangning Wang,Mingkai Bai,Adewale Olusegun Obadina,Shiyang Li,Guangxin Feng,Haohao Wu
Microalgae are a sustainable and nutrient-dense food source, but their strong off-flavors significantly limit broader consumption. This study evaluates the effectiveness of a laccase-catechin mediator in improving the odor profiles of Spirulina, Chlorella, and Chlamydomonas reinhardtii . Mediators were applied ex situ (pre-formed) or in situ (generated within the suspension). Ex-situ mediators, optimized at 40 °C for 2 h, achieved better deodorization compared to in-situ mediators, with optimal catechin dosages of 28, 16, and 8 mg/g biomass for Spirulina, Chlorella, and C. reinhardtii , respectively. Sensory evaluation showed reduced grassy, earthy, and fatty odors, and enhanced floral and fruity notes, with the ex-situ approach leading to higher overall acceptability. GC–MS analysis confirmed that mediators decreased the diversity and abundance of key odor-active volatiles in three microalgae species. Laccase-catalyzed quinone-type mediators effectively neutralize undesirable compounds, offering a promising enzymatic strategy for improving the sensory quality of microalgae-based foods, especially for sustainable food applications.
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Sustainable Materials and Technologies
·
2026
·
IF 9.7
Shafqat Ali,Sajjad Ali,Wenbo Yang,Shixuan Yan,Raheel Akram,Asif Shahzad,Zareen Zuhra
Gold recovery from waste remains challenging due to the lack of materials that can simultaneously coordinate, reduce and stabilize Au species. Herein, we report a hierarchical redox-engineered copper(II) benzenehexathiol metal-organic framework (BHT MOF) featuring six thiolate coordination sites, uniformly grown on a three-dimensional carbon nanotube sponge (BHT MOF@CNT sponge), for the selective recovery of waste gold ions and their direct conversion into catalytically active gold nanoparticles (Au NPs). The hybrid material exhibits high gold adsorption capacity of 647.9 mg g −1 at pH 1.0 and 50 °C, coupled with outstanding selectivity, showing only a 5–10% decrease in Au uptake in the presence of 11 competing metal ions and achieving a total gold recovery efficiency exceeding 90% in both binary and multicomponent systems. The conformal growth of the BHT MOF on the conductive CNT sponge generates a hierarchical porous architecture with sulfur-rich active sites that provide strong Au-S coordination and thermodynamically favorable binding. Simultaneously, the redox-active thiolate ligands facilitate spontaneous in situ electron transfer, driving the reduction of Au(III) to metallic Au(0) and enabling the formation of uniformly dispersed Au NPs confined onto the hybrid matrix, without the need for external reducing agents or post-synthetic treatments. The resulting Au-BHT MOF@CNT catalyst exhibits an enhanced hydrogen generation rate and excellent cycling stability, benefiting from the synergistic interplay between thiolate-based redox engineering, strong metal-support interactions and accelerated electron transport through the CNT network. This work demonstrates a scalable waste-to-energy platform that integrates waste gold recovery and hydrogen production within a single multifunctional material, providing a sustainable strategy for precious metal recycling and clean energy generation.
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JOURNAL OF FOOD PROCESSING AND PRESERVATION
·
2022
·Vol. 46
·期 3
·e16372
·
IF 2.609
Haixia Ye,Jinmin Wen,Shiyun Wang,Ying Zhang,Bingbing Wu,Siwei Liu,Xinru Chen,Yongqian Xiao,Chengtao Wang,Jianjun Hou,Ming Ni,Xian Xia,Yulin Li
Prolonging shelf life of fresh-cut water chestnuts (FCWC) by vitamin E (vit E) was investigated. Browning degree, decay degree, and edible quality (EQ) of FCWC were evaluated as evaluation indexes of shelf life. Meanwhile, total soluble solids concentration, titratable acid (TA) concentration, ascorbic acid (AA) concentration, hardness, ethylene concentration, polyphenol oxidase (PPO) activity, peroxidase (POD) activity, total phenols (TP) concentration, counts of thermophilic bacteria, yeasts, and molds colonies were analyzed. Shelf life of FCWC could be prolonged for 4 days by soaking them in 0.04% (v v −1 ) vit E anhydrous ethanol (1% [v v −1 ]) solution for 30 min. Vit E probably inhibited the increasing of PPO and POD activities, and the declining of TP concentration and hardness. Vit E had little effect on counts of thermophilic bacteria, yeasts, and molds colonies of FCWC. These results indicated that vit E could prolong shelf life of FCWC. Novelty impact statement Vitamin E (vit E) extents shelf life of fresh-cut water chestnuts for 4 days. Vit E inhibits browning by reacting with oxygen or by reducing polyphenol oxidase and peroxidase activities. Vit E has no effect on total soluble solids, titratable acid, ascorbic acid, and ethylene concentration.
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ACS Omega
·
2023
·
IF 4.1
Yuzhu Li,Kangzhuo Yang,Zhanglan He,Zhipeng Liu,Jialing Lu,Dong Zhao,Jia Zheng,Michael C. Qian
Electronic nose (E-nose) technology is frequently attempted to simulate the human olfactory system to recognize complex odors. Metal oxide semiconductors (MOSs) are E-noses’ most popular sensor materials. However, these sensor responses to different scents were poorly understood. This study investigated the characteristic responses of sensors to volatile compounds in a MOS-based E-nose platform, using baijiu as an evaluation system. The results showed that the sensor array had distinctive responses for different volatile compounds, and the response intensities varied depending on the sensors and the volatile compounds. Some sensors had dose–response relationships in a specific concentration range. Among all the volatiles investigated in this study, fatty acid esters had the greatest contribution to the overall sensor response of baijiu. Different aroma types of Chinese baijiu and different brands of strong aroma-type baijiu were successfully classified using the E-nose. This study provided an understanding of detailed MOS sensor response with volatile compounds, which could be further applied to improve the E-nose technology and its practical application in food and beverages.
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CARBOHYDRATE POLYMERS
·
2023
·
IF 11.2
Chuang Wang,Yiqi Liao,Hou-Yong Yu,Yanjuan Dong,Juming Yao
Fiber-based wearable electronic textiles have broad applications, but non-degradable substrates may contribute to electronic waste. The application of cellulose-based composite fibers as e-textiles is hindered by the lack of fast and effective preparation methods. Here, we fabricated polyaniline (PANI)/cellulose fibers (PC) with a unique skin-core structure through a wet-spinning homogeneous blended system. The conductive network formation was enabled at a mere 1 wt% PANI. Notably, PC15 (15 wt% PANI) shows higher electrical conductivity of 21.50 mS cm −1 . Further, PC15 exhibits excellent ammonia sensing performance with a sensitivity of 2.49 %/ppm and a low limit of detection (LOD) of 0.6 ppm. Cellulose-based composite fibers in this work demonstrate good gas sensing and anti-static properties as potential devices for smart e-textiles.
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危险品化学品经营许可证（带存储）