Journal of Physical Chemistry C
·
2025
·
IF 3.2
Jia-Yi Zhang,Si-Ting Liu,Zhen-Long Dou,Cong-Cong Zhang,Guo-Wei Li,Si-Jing Ding,Li Zhou,Qu-Quan Wang
Hybridization is an effective strategy to obtain complementary and synergistic properties from each component. This study describes an intriguing approach for the synthesis of rod-shaped Cu2S/AgPtSe2–Au hybrids with improved photothermal capabilities. The synthesis protocol involves a silver-mediated method for depositing the topological semimetals of PtSe2 onto the surface of Au nanorods, followed by wrapping a layer of Cu2S with high carrier concentration and mobility. The formed heterojunctions exhibit enhanced light absorption properties and accelerated charge separation of photoexcited carriers. Under excitation of a near-infrared 1064 nm laser, the hybridized Cu2S/AgPtSe2–Au shows enhanced photothermal conversion, with a 2.5-time temperature increase (ΔT) than that of bare Au nanorods.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2019
·Vol. 187
·期 1
·1-11
·
IF 5.479
Wang Qian-Long,Huang Wei-Xue,Zhang Pu-Juan,Chen Li,Lio Chon-Kit,Zhou Hua,Qing Lin-Sen,Luo Pei
An ultra-sensitive method is described here for the determination of HIF-1α (an early biomarker for myocardial infarction) in circulating exosomes in serum. Gold nanospheres were functionalized with a HIF-1α-binding aptamer via sulfydryl chemistry. The apt-AuNP-coated gold seeds were grown by seed-mediated growth, and this significantly increased the peroxidase-mimicking property the nanoparticles. A chromogenic system composed of 3,3′5,5′-tetramethylbenzidine and hydrogen peroxide was used. Absorbance at 652 nm increases linearly in the 0.3 to 200 ng L −1 HIF-1α concentration range, and the limit of detection is 0.2 ng L −1 . The method was tested by analyzing rat serum from isoproterenol (ISO)-induced myocardial infarction. It allows HIF-1α to be directly determined in a 25 μL sample without preconcentration. The assay is not interfered by the polydispersity of exosomes released under either health and disease conditions.
Gold nanospheres were functionalized with a HIF-1α-binding aptamer via sulfydryl chemistry. Nanosized gold seed particles were then modified with the functionalized gold nanospheres, and this strongly increases the peroxidase-mimicking activity of the nanomaterial. By using the tetramethylbenzidine/H 2 O 2 chromogenic system, the absorbance at 652 nm increases linearly in the 0.3 to 200 ng L -1 HIF-1α concentration range.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Chemical & Biomedical Imaging
·
2025
·
IF 5.7
Zhuohan Jing,Fangdong Long,Yuxiao Xiong,Jiaqi Liu,Zhaoju Li,Haolin Chen,Zhiming Liu,Bo Xu
Mitophagy is closely associated with various diseases. Precise monitoring of its dynamics and understanding its mechanisms are crucial for diagnosing and treating mitophagy-related diseases. This study developed a mitochondria-targeted (MT) surface-enhanced Raman scattering (SERS) nanoprobe to investigate the drug-induced mitophagy through unveiling the mitochondria-related metabolic profiling. The MT-SERS nanoprobe is consist of carbon dots coated with gold nanoparticles functionalized with triphenylphosphonium (Au@CDs-TPP) that exhibits exceptional SERS performance, low cytotoxicity, and mitochondria targeting specificity. Au@CDs-TPP is first used to monitor the classic mitophagy triggered by carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone (FCCP), which demonstrates the diverse metabolic profiling related to mitochondria, like degradation in mitochondrial protein, DNA damage, decreased lipid and cytochrome c content, and increased carbohydrate consumption. We further evaluate the cellular response to anesthetic lidocaine, which can also induce mitophagy in HepG2 cells like FCCP. However, the molecular alterations in lidocaine-induced mitophagy fluctuated differentially compared to that in FCCP-induced mitophagy.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Russian Journal of Physical Chemistry A
·
2023
·Vol. 97
·期 13
·3120-3125
·
IF 0.7
Li Zhong,Yuan Tiantian,Tang Shuqin,Chen Xiangting
Abstract A novel 2D bone-like Au nanoplates/graphene oxide composites have been successfully synthesized using a facile ultrasonic-assistant seed-mediated approach. The morphology and structure were investigated by transmission electron microscope (TEM), high-resolution transmission electronic microscopy (HRTEM) and X-ray photoelectron spectra (XPS). Studies found that the as-synthesized 2D Au nanoplates with relatively good distribution are bone-like morphologies with a length of about 50 nm and a width of about 30 nm. The catalytic activity of as-synthesized products was investigated for the reduction of 4-nitrophenol to 4-aminophenol, and it was seen that the 2D bone-like Au nanoplates/graphene oxide composites exhibited significant enhancement in catalytic activity.
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.1
Haiyan Zhang,Sen Liu
Chemiresistive gas sensors based on metal oxides hold a great potential for gas monitoring applications, but applications of these sensors are hindered by inadequate material properties for traditional metal oxides. Herein, we demonstrated the preparation of Au nanoparticles (NPs)-loaded spinel-structured high entropy oxides (Au-HEO) for acetone sensing applications, where Au-HEO was prepared by deposition of Au NPs onto the surface of HEO with the composition of (FeCoCrNiZn) 3 O 4 obtained by glycine-assisted sol-gel method. Experimentally, Au-HEO sensor shows the response value of 1.49 toward 100 ppm acetone at 180 °C, good repeatability and good selectivity. Notably, the Au-HEO sensor not only displays low resistance, compared to traditional metal oxides, but also shows enhanced sensitivity toward acetone compared to pristine HEO. This study paves the way for designing and developing highly efficient functional materials for gas sensing applications.
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 7.7
Yixue Chen,Huaiyu Song,Yan Qin,Yu Liu,Ying Xie,Zhenyu Chu,Wanqin Jin
Pyruvate is one of the most important intermediate metabolites in the fermentation process, thereby making it a potential indicator for monitoring and regulating the fermentation process. Since the fermentation broth is usually complex, including microorganisms, various ions, organic compounds, etc., it is necessary to develop a highly selective method for detecting pyruvate. Therefore, in this work, we proposed an ultrasensitive electrochemical enzymatic biosensor for pyruvate determination at a low working potential through constructing Prussian blue@Au nanoframes (PB@Au NFs) with improved conductivity and high electrocatalytic ability. Due to the strong catalytic ability of PB nanoframes for the reduction of H 2 O 2 , the as-prepared sensor initially demonstrated extremely 2.7-fold sensitivity toward H 2 O 2 than the non-frame structured PB nanocubes. Furthermore, after the conditions for pyruvate detection were systematically optimized, the fabricated sensor was able to effectively identify pyruvate ranging from 5 μM to 0.895 mM at -0.2 V which represented an orders-of-magnitude improvement in sensitivity over existing sensors. Meanwhile, the low working potential and the highly precise recognition ability of pyruvate oxidase ensured the high selectivity of the prepared sensor, and the sensor also showed excellent reproducibility and long-term stability. Finally, our biosensor was employed to detect pyruvate in the real microbial fermentation liquid, giving an excellent accuracy with RSD values of 1.44% - 4.64%. This work provides a new strategy approach for the design and establishment of stable pyruvate sensors and offered a usefulness approach for the pyruvate detection with high performance.
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2020
·
IF 5.339
Rui Gao,Dan Li,Siqing Zheng,Haixin Gu,Wei Deng
Accurate and selective in-field detection of metal ions in complex media has gained wide interests due to the complexed matrices and weak affinity towards sensing surface. Herein, we develop a first trimodal method for sensing of Zn 2+ in complex matrices by stimuli-responsive N-[6-piperazinyl-2-pyridinyl]-N-(2-pyridinylmethyl)-2-Pyridinemethanamine dithiocarbamates (DPY) modified gold nanorods (GNRs-DPY). The presence of Zn 2+ triggers the aggregation of GNRs-DPY, leading to increment of color and fluorescence intensity of the sensing system, which could be visually discerned with bare eye. Moreover, the intensive electromagnetic enhancement among “hot spots” of GNRs, generated during self-aggregation of the GNRs-DPY caused by Zn 2+ , lowers the detection limit of SERS assay to 6 × 10 −3 pM. It is noteworthy that GNRs-DPY based sensing platform not only enables distinguishing Zn 2+ from Cd 2+ , with simplicity and rapidity, but also demonstrates as trimodal nanoprobe for sensitive and selective quantitative determination of Zn 2+ in different matrices. Therefore, the GNRs-DPY provides a new strategy for accurate and credible on-spot determination of Zn 2+ in complicated specimens, as well as offering multiple applications in point-of-care monitoring.
研究领域:
分析化学
·
纳米生物技术
·
环境监测
·
分子诊断
·
金属离子传感
✓ 已验证
DOI
高影响因子
CRYSTENGCOMM
·
2012
·Vol. 14
·期 20
·6581-6585
·
IF 3.842
Shaozhen Wang,Long Kuai,Xing Han,Baoyou Geng
Multi-twinned Au nanostructures expose more corners and edges than other usual nanostructures. In addition, there are many defects on the surface of the multi-twinned nanostructures, so that they can supply many active sites for electrocatalytic reactions. This paper reports unusual branched twinned Au nanostructures in a facile hydrothermal reduction system based on theoretical analysis and experimental exploring. According to the time-dependent and relative experiments, an etching/re-crystallization growth mechanism is proposed. Besides, the electrochemical investigations suggests that the branched twinned Au nanostructures exhibit enhanced electrocatalytic ORR performance in alkaline media compared with sphere-like Au nanoparticles, because of the higher chemical activity of the corner, edge atoms and defects. Namely, the reduction peak potential of O2 is positive-shifted by 48 mV compared with Au nanoparticles, and the reduction peak current density is 1.45 times that of the Au nanoparticles. Thus, our work enriches the theoretical study of twinned noble metallic nanostructures and accelerates the development of cathodic electrocatalysts for alkaline fuel cells.
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2012
·
IF 3.461
Li Sun,Weiling Luan,Yuejin Shan,Shan-tung Tu
Monodisperse Au–Ag alloy nanoparticles were synthesized by a one-step rapid injection method in a capillary microreaction system with a short residence time (less than 3 min). Au–Ag alloy NPs possessed homogenous composition that revealed a linear relationship with surface plasmon resonance absorption peak. The optimal size distribution of Au–Ag alloy NPs with a standard deviation of 6% could be obtained from decreasing the molar ratio of Au 3+ :Ag + from 1:10 to 1:20 or enhancing the synthesis temperature from 140 to 160 °C. Transmission electron micrographs showed as-obtained Au–Ag alloy nanoparticles were sphere-like with the smallest average size of only 2.7 nm.
研究领域:
纳米医学
·
材料科学
·
生物材料
·
药物递送
·
分子影像
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2026
·Vol. 61
·期 27
·19522-19536
·
IF 4.4
Zhang Xi-Hao,Liu Jie,Chen Lan,Zhou Zhigang,Deng Tian-Song
Combining gold nanostructures with cuprous oxide semiconductors can integrate the plasmon resonance effects of noble metals with the visible-light-responsive properties of semiconductors, offering a novel approach to enhancing photocatalytic performance. In this study, we employed Au nanocup as the core component—a nanomaterial featuring a three-dimensional asymmetric structure that exhibits remarkable localized surface plasmon resonance and high specific surface area. By varying the amount of copper precursor, we successfully synthesized a series of Au nanocup@Cu 2 O core–shell composites with different Cu 2 O shell thicknesses. The influence of shell thickness on the optical properties and photocatalytic performance was systematically investigated. In the photocatalytic degradation of methyl orange under visible-light irradiation, the optimized composite demonstrated significantly enhanced activity, with the degradation efficiency being more than 12 times higher than that of pure Au nanocup or pure Cu 2 O. The performance improvement is attributed to two main factors: the efficient transfer of plasmon resonance energy from the Au nanocup to the Cu 2 O shell, which promotes charge generation and separation, and the formation of a heterojunction interface that facilitates charge transport. This study provides new insights for designing efficient photocatalysts and shows promising potential for environmental remediation applications.
✓ 已验证
DOI
高影响因子
CATALYSIS LETTERS
·
2026
·Vol. 156
·期 8
·220
·
IF 2.5
Shi Yinhu,Ma Jiping,Zhang Yunwei,Wang Shuwei,Wang Xinhong
The selective and sustainable production of methyl lactate from biomass-derived polyols remains a significant challenge due to the frequent requirement of homogeneous bases. Herein, an integrated Au/CuO catalyst is reported for the base-free oxidative esterification of 1,2-propanediol to methyl lactate. The Au/CuO catalyst exhibits superior catalytic performance compared with Au supported on other oxides, affording high conversion and selectivity under optimized conditions. Systematic studies reveal that moderate Au loading and reaction conditions are crucial for suppressing over-oxidation and C-C bond cleavage. Mechanistic investigations suggest that the reaction proceeds via parallel oxidation pathways involving both primary and secondary hydroxyl groups, while the Au-CuO interface plays a key role in regulating intermediate oxidation and stabilizing methyl lactate. This work highlights the importance of metal-oxide interfacial effects in base-free oxidative esterification and provides a sustainable route for methyl lactate production from renewable polyols. Graphical
✓ 已验证
产品关联
DOI
高影响因子
Small
·
2026
·
IF 11.8
Yuehui Chen,Zheng Yang,Panpan Gao,Songmei Sun,Weiyan Zhu,Jianhua Yan
Constructing photocatalysts with multidimensional active site architectures represents a powerful strategy for boosting visible-light-driven VOC degradation efficiency. Here, we report a structure regulation strategy achieved through interface coupling of a bimetallic gold-bismuth (Au-Bi) nanodot network with heteromorphic Bi 2 WO 6 composed of mesoporous nanofibers and nanosheets. This yields distinctive Au-Bi nanodot-anchored 1D/2D Bi 2 WO 6 photocatalysts exhibiting optimized charge transfer pathways and amplified surface reactivity. The bimetallic Au-Bi network collaboratively forms multi-scale Schottky junctions, effectively promoting the separation of photogenerated electron-hole pairs while simultaneously enhancing visible-light absorption via localized surface plasmon resonance effects. Concurrently, the in situ formation of 0D Au-Bi nanodots and heteromorphic 1D/2D Bi 2 WO 6 during reduction sintering induces abundant oxygen vacancies, promoting oxygen activation and reactive oxygen species generation. The multidimensional 0D/1D/2D Au-Bi/Bi 2 WO 6 photocatalyst rapidly and thoroughly degrades acetaldehyde, achieving degradation rates 13.2-fold and 5.92-fold higher than those of 1D/2D Bi 2 WO 6 and 1D/2D Bi-Bi 2 WO 6 , respectively. Moreover, this catalyst maintains exceptional stability across five consecutive cycles. This work pioneers an innovative methodology for designing high-performance heterogeneous photocatalysts.
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）