ANALYTICA CHIMICA ACTA
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2020
·
IF 5.977
Jun-Tao Cao,Yu-Xiang Dong,Yan Ma,Bing Wang,Shu-Hui Ma,Yan-Ming Liu
Photoactive materials with high photo-electron transfer efficiency and stable signal output hold a key role in constructing the photoelectrochemical (PEC) biosensing systems. In this study, the ternary [email protected] 3 N 4 heterojunction was first prepared and characterized, and its application in PEC bioanalysis was explored. The gold nanoparticles sandwiched between CdS and g-C 3 N 4 , acting as both plasmonic photosensitizer and electron relay, significantly boosted the light absorption and accelerated the charge transfer from g-C 3 N 4 to CdS, both of which contributed to the enhancement of photoelectric conversion efficiency. Signal quenching with graphene oxide-CuS efficiently weakened the photocurrent from [email protected] 3 N 4 . The combination of the excellent PEC properties of [email protected] 3 N 4 and the remarkable quenching effects of graphene oxide-CuS enabled construction of a sandwich-type PEC immunosensor for prostate specific antigen (PSA) detection. This immunosensor achieved sensitive PSA analysis by multiple signal amplification mechanisms, with a detection limit of 0.6 pg mL −1 and a wide linear range from 1.0 pg mL −1 to 10 ng mL −1 . This work not only demonstrates the great potential of noble metal sandwiched ternary heterojunctions in the PEC field, but also lays a foundation for developing the general PEC immunoassays .
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2020
·
IF 3.573
Jincheng Mu,Jianfang Liu,Zhenzhen Ran,Muhammad Arif,Min Gao,Chen Wang,Shengfu Ji
MOF-808(Zr) with the coordinated unsaturated (CUS) Zr4+ centers was synthesized by the thermal reflux method, and a series of Au/MOF-808(Zr) catalysts with different Au loading percentages have been prepared by the impregnation–reduction method. The related X-ray diffraction, Fourier transform infrared spectroscopy, high-resolution transmission electron microscopy, X-ray photoelectron spectroscopy, N2 adsorption–desorption, Inductively coupled plasma-mass spectrometry, and NH3 temperature-programmed desorption characterizations have been undertaken to understand the structure of catalysts. The catalytic activity in CO2 with aniline/H2 to N-methylation and N-formylation has been studied in a batch reactor. Results show that the MOF-808(Zr) structures in catalysts are of high quality and damage-free. The Au nanoparticles (NPs) are highly dispersed on the surface of the MOF-808(Zr) cage with a mean size of 2–20 nm. Also, the catalysts could catalyze the conversion of CO2 with aniline/H2 to N-methylation and N-formylation products with a high efficiency. With a 3.0 wt % Au/MOF-808(Zr) catalyst, the conversion of aniline is 18.4%, and the selectivity of N-methylaniline is 80.9% and that of N,N-dimethylaniline is 19.1%. The preliminary reaction mechanism and the critical role of CUS were also studied. It is determined that H2 is adsorbed and activated on Au NPs. CO2 is adsorbed on the CUS Zr4+ acidic sites and O2– basic sites. The primary and secondary amines are adsorbed on the CUS Zr4+ acidic sites, where they react with CO2 and H2 to form N-formamide. Subsequently, N-formamide reacts with activated H2 to yield N-methylamine.
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BIOSENSORS & BIOELECTRONICS
·
2018
·
IF 8.173
Xianzhen Song,Xiaojian Li,Dong Wei,Rui Feng,Tao Yan,Yaoguang Wang,Xiang Ren,Bin Du,Hongmin Ma,Qin Wei
In this work, 3,4,9,10-perylenetetracar-boxylic acid (PTCA) as luminophor was grafted on the surface of graphene oxide (PTCA-GO) directly. GO exhibited large specific surface area and excellent electrical conductivity which can immobilize large amounts of PTCA to improve the electrochemiluminescence (ECL) efficiency. Moreover, gold nanoparticles (Au NPs) were anchored on the surface of PTCA-GO to immobilize primary antibodies (Ab 1 ) via Au-NH 2 bond and enhance the electron transport of PTCA-GO. CuS was used as a novel co-reaction accelerator in PTCA-K 2 S 2 O 8 system to label secondary antibodies (Ab 2 ), which can react with the coreactant (K 2 S 2 O 8 ) to produce more SO 4 •- . SiO 2 nanospheres with large specific surface area were used to load a mass of CuS and Au NPs, which can directly combine with Ab 2 and accelerate the ECL emission remarkably. Therefore, a novel sandwich-type ECL immunosensor was fabricated successfully for amyloid-β protein (Aβ) detection. Under the optimal condition, a wide detection range from 50 fg/mL to 25 ng/mL and a low detection limit of 18 fg/mL (S/N = 3) were obtained. Featuring favorable specificity, stability and reproducibility, the strategy can be a powerful analytical tool in sensitive trace detection of biomolecules in clinical analysis.
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Journal of Materials Chemistry C
·
2024
·
IF 5.7
Sheng Zhang,Junyin Cheng,Bo Song,Shun Linghu,Yijun Tang,Qing Li,Lei Chen
Winter sports have gained popularity in recent years. These sports and activities, however, come with some health concerns, particularly in harsh and extremely cold conditions. A self-heating, flexible, and smart conductive material that can monitor body health in extreme conditions would thus be highly desirable. Inspired by the structure of a spider-web, a flexible pressure sensor was developed by depositing a CNTs/CuS composite coating on a fabric surface with a cellulose-entangled structure constructed by hydroxypropyl methyl cellulose (HPMC). The obtained flexible pressure sensor demonstrated stable physiological signal detection and temperature insensitivity during photothermal heating, attributed to the water-retention capacity of HPMC. In addition, it exhibited excellent electrical conductivity (resistance of 10 Ω cm−1), deicing (181s), sterilization (≈99.99%), UV resistance (UPF ≈ 13 926), environmental adaptability (−78 °C to 50 °C) and high sensitivity (13.25 ± 0.123 kPa−1). This coating process can be applied to various garments, offering new possibilities for designing and preparing wearable multifunctional sensors.
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Journal of Cleaner Production
·
2020
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IF 7.246
Hongping He,Mei Sun,Deli Wu,Guanglan Di,Xunchang Fei
Heterogeneous Fenton dominated by ·OH is limited in its application, as pre-acidification is required to maximize the generation amount and redox potential of ·OH. It is thus featured to consume resources and generate pollutants. In this study, both CuS/H 2 O 2 and Cu 2 S/H 2 O 2 are found to show better performances under close-to-neutral condition (pH 5.0 to 9.0) than acidic condition (pH 3.0) when degrading a model contaminant, sulfamethazine (SMZ), because ·OH does not play a major role in both systems. The Cu valence-dependent catalytic mechanisms are responsible for the varied kinetics between CuS/H 2 O 2 and Cu 2 S/H 2 O 2 . In CuS/H 2 O 2 , Cu(III) and 1 O 2 contribute to the SMZ degradation, and their contributions are pH-dependent. In Cu 2 S/H 2 O 2 , Cu(III) is responsible for the degradation regardless of the pH. Both systems with optimal performances under neutral condition are advantageous as pre-acidification can be avoided. In addition, air sparging induces additional 16% SMZ degradation in Cu 2 S/H 2 O 2 under acidic condition, because the sparged O 2 reacts with dissolved Cu(I). The more O 2 reacts with the dissolved Cu(I), the less generated Cu(III) is ineffectively depleted. Air sparging is readily applicable to different operations, thus its combination with Cu 2 S/H 2 O 2 potentially benefits the development of environmentally-friendly treatment process for industrial wastewater .
研究领域:
环境科学
·
化学工程
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APPLIED THERMAL ENGINEERING
·
2026
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IF 7.5
Xiaoyu Song,Xuenong Gao,Ziye Ling,Zhengguo Zhang,Yuyuan Zhuang
This study proposes the combination of copper sulfide‑carbon nanotubes (CuS-CNTs) photothermal material with paraffin/expanded graphite. A flat-plate collector based on this material is also designed. Unlike traditional collectors that integrate phase change materials, the composite phase change material in this design can directly absorb sunlight and store heat. The goal is to reduce heat loss from the collector and improve system stability and efficiency. The novelty of this study lies in the preparation of a composite phase change material with high photothermal conversion efficiency, high thermal conductivity, and good shape stability. This material can realize the integration of photothermal conversion and thermal energy storage inside the collector. Key results show that when the CuS-CNTs content is 10%, the photothermal conversion efficiency of the composite phase change material increases from 61.07% to 94.03%. The total efficiency of the solar water heating system reaches as high as 56%. These results indicate that the addition of CuS-CNTs can significantly improve the photothermal conversion efficiency of the material. The prepared composite phase change material has great application prospects in the field of solar energy. In addition, this work uses numerical simulation for analysis. The optimal parameter combination for the collector is determined as an upper layer material density of 0.8 g/cm 3 , a lower layer material density of 0.8 g/cm 3 , and a thickness ratio of 1:1. These findings provide reference and guidance for the structural design of high-performance flat-plate collectors.
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MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 11
·1-11
·
IF 6.232
Cui Ying,Li Junhua,Liu Mengqin,Tong Haixia,Liu Zeng,Hu Jiawen,Qian Dong
A novel hybrid with three-dimensional (3D) hierarchical CuS@Pd core-shell cauliflowers decorated on nitrogen-doped reduced graphene oxide (CuS@Pd/N–RGO) has been prepared by a facile wet-chemical route without utilizing any template molecules and surfactants. The characterization results reveal that the 3D flower-like structure of CuS “core” is composed of interconnecting nanoplates, which is conductive to the loading of Pd nanoparticles’ “shell” and results in the robust interaction between the core and shell for the formation of CuS@Pd cauliflowers. Anchoring such appealing CuS@Pd cauliflowers on the two-dimensional N–RGO can efficaciously inhibit the aggregation of CuS@Pd cauliflowers and accelerate the kinetics of xanthine oxidation. Benefiting from the multi-functional properties and unique morphology, the sensor constructed by CuS@Pd/N–RGO exhibits excellent performance for non-enzymatic detection of xanthine including a wide detection range of 0.7–200.0 μM (0.94 V vs. SCE), a low detection limit of 28 nM (S/ N = 3), high reproducibility (relative standard deviation (RSD) = 4.1%), and commendable stability (retained 90% of the initial electrochemical responses after storage for 30 days), which is amongst the best of various electrochemical sensors reported for xanthine assays till date. Reliable and satisfying recoveries (95–105%, RSD ≤ 4.1%) are achieved for xanthine detection in real samples. The inspiring results make the uniquely structural CuS@Pd/N–RGO greatly promising in non-enzymatic electrochemical sensing applications.
A high-performance non-enzymatic xanthine sensor has been constructed by the three-dimensional hierarchical CuS@Pd core-shell cauliflowers decorated on nitrogen-doped reduced graphene oxide.
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高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Ming Yuan,Xiangwei Yuan,Yao Jin,Yingbo Shi,Zhirong Zou,Xiaoli Xiong
Gallic acid (GA) is a kind of polyhydroxyl phenolic compound, which has good antioxidant function and widely exists in plants, fruits, beverages and drugs. The quantitative detection of GA content is very important for the quality control of human health food and drugs. In this study, 2D (two-dimensional) Cu-benzenedicarboxylate (Cu-BDC) nanosheets are used as precursor to derive CuS nanoparticles embedded in porous carbon (CuS@C) with peroxidase-like activity, which can catalyze colorless 3,3′,5,5′-tetramethylbenzidine (TMB) in the presence of H 2 O 2 , while the antioxidant GA can compete with TMB resulting in a concentration dependent color change in GA. Based on this competitive relationship, a colorimetric platform for GA detection is established with a linear range of 0.5–60 μM and a limit of detection of 0.19 μM under optimal conditions. The mechanism studies indicate that ·OH radicals are the primary active species. In addition, a smartphone-assisted GA quantitative detection mode is further constructed based on the RGB principle with a detection limit of 0.27 μM. The study offers a reliable method for the rapid visual detection of GA in the tea and health care products, and also provides a reference for the design of new nanozymes.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Yun Zeng,Yonghua Zhan,Xinyue Liu,Jingwen Ma,Huifang Liu,Hanrui Li,Tong Yi,Qingxia Zhu,Getao Du,Linfei Zhao,Dan Chen,Xueli Chen
Tumor metastasis is a major cause of poor cancer prognosis. Photothermal therapy (PTT) is a non-invasive, non-oxygen-dependent, and highly spatiotemporally precise treatment that may aid chemotherapy in suppressing tumor growth and metastasis. This article aims to develop and modify a CuS-based nanoplatform linking RGD-Acrk to actively target and internalize doxorubicin (DOX) into tumor cells, resulting in an alternating strategy of synergistic chemo/PTT. The nanoparticle’s shape, spectra, drug encapsulation efficiency, loading content, and controlled release are characterized, and a comparison of 808/980 nm lasers is used to irradiate the nanoplatform. The cell survival rate is used to determine the cytotoxicity of DOX and PTT, and the chemo/PTT is used to treat 4T1-Luc tumor-bearing mice. Simultaneously, bioluminescence and photoacoustic imaging are employed to assess therapy efficacy, as well as tumor size, weight, density, the bodyweight of mice, and survival curves. H&E, immunohistochemistry for HIF-1α, and TUNEL fluorescence staining confirm these findings, suggesting that the nanoplatform has a good active-targeted capacity and perform high-efficiency PTT caused by 980 nm laser irradiation. The synergistic effect is at least 3.53 times higher than chemo/PTT without synergistic effect and tumor liver metastasis is successfully suppressed, showing that it has the potential to be used for cancer treatment and prognosis improvement.
研究领域:
肿瘤学
·
纳米技术
·
诊疗学
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高影响因子
APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Yanlei Liu,Mengbo Shan,Lange Du,Weihao Sun,Dapeng Wu,Qing Bi,Hongju Wang,Yufang Liu
A scalable strategy with commercial feasibility was developed to in situ generate TiO 2 nanowires/amorphous CuS@TiO 2 nanolayer (TiO 2 /CuS@TiO 2 ) composites on the surface of titanium mesh through a sequent hydrothermal method, successive ionic layer adsorption and reaction (SILAR), and atomic layer deposition (ALD) techniques. The TiO 2 /CuS@TiO 2 composites could respectively harness the incident light with different spectra at the photothermal center (CuS, visible and near-infrared light) and photocatalytic center (TiO 2 , UV and visible light), which leads to the effective utilization of the solar energy. Benefiting from the CuS photothermal-induced local heating effect of CuS, the adjacent micro-zone temperature could be elevated and the activation energy barrier could be reduced by 10.5 kJ mol −1 , which promotes the activation of surface lattice oxygen and dissolved oxygen in the photocatalytic process. Meanwhile, the ALD generated TiO 2 nanolayer could both serve as reactive centers but also protecting armor for the CuS, which prohibited the peeling and oxidation of the thermal centers, leading to a high stability of the photocatalyst, which exhibits no obvious fading after 20-cycle reuse. A flow reactor was conceived and made by 3D print and the Ti-mesh based photocatalyst was integrated, which demonstrates high photocatlytic performances, manifesting its great potential for large-scale water treatment.
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 4
·123412
·
IF 7.5
Jiahao Ouyang,Yulin Chen,Xiaonuo Li,Jiahao Li,Qiu Xia,Kai Huang,Guangyang Wang,Yong Ye
To address enzyme inactivation upon immobilization and the underutilization of surplus glycerol from biodiesel production, a near-infrared (NIR)-responsive bioconjugate was developed which comprised Candida antarctica lipase B (CALB) immobilized on a CuS/Cu-TCPP support. In this design, Cu-TCPP (a porphyrin-based metal-organic framework) provides a high-surface-area scaffold, CuS nanoparticles act as NIR photothermal converters, and hydrophobic surface modification enhances lipase adsorption. XRD, XPS, SEM, and TEM confirmed the formation of covellite-structure CuS on Cu-TCPP and successful enzyme immobilization. The system achieves a photothermal conversion efficiency of 22.70% (defined as the ratio of heat generated to absorbed laser energy), retains 99.52% of its initial activity at 70 °C, and preserves 74.20% activity after five reuse cycles. During glycerol esterification under NIR irradiation (808 nm) at room temperature, oleic acid conversion reaches 69.2%, representing a 2.42-fold increase compared to the non-irradiated control (28.6%). Bandgap analysis (1.66 eV > 1.53 eV) confirms the absence of reactive oxygen species generation, preventing enzyme oxidative inactivation. This work enables remote, real-time, and precise control of lipase catalysis via localized photothermal heating, offering a green strategy for glycerol valorization.
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BIOMATERIALS
·
2021
·
IF 12.479
Zengjie Zhang,Yikai Wang,Wangsiyuan Teng,Xingzhi Zhou,Yuxiao Ye,Hao Zhou,Hangxiang Sun,Fangqian Wang,An Liu,Peng Lin,Wenguo Cui,Xiaohua Yu,Yan Wu,Zhaoming Ye
Tissue damage caused by hyperthermia during photothermal therapy (PTT) has largely limited its clinical applications for implant infection. However, rescue of tissue regeneration by conjugating orthobiologics with PTT has been problematic as they can easily deactivate biologics while eradicating bacteria. Herein, we report an orthobiologics-free strategy to synergistically couple photocatalytic antibacterial with pro-osteogenic capacity via self-assembly of copper sulphide nanoparticle (CuS NP) and reduced graphene oxide (rGO) on implant surface . This strategy not only offers enhanced photothermal effects for bacterial eradiation via near-infrared light (NIR), but also promotes vascularized osseointegration via cooperation of copper ion with rGO. In vitro and in vivo data showed that coupling CuS and rGO synergistically increased antibacterial efficacy of implants by 40 times and successfully destroyed bacterial biofilm upon NIR. Moreover, CuS/rGO decorated surface substantially improved bone marrow stromal cell adhesion , proliferation, as well as subsequent differentiation toward osteoblast. We also revealed that enhanced peri-implant vascularization may be attributed to the sustained release of copper ion from CuS NPs, which further collaborated with rGO to promote vascularized osseointegration. Altogether, this novel orthobiologics-free approach offers a practical alternative to circumvent the intrinsic drawbacks of PTT and endows powerful antibacterial and pro-osteogenic capacities for implant associated infections.
研究领域:
生物材料
·
纳米技术
·
生物医学工程
·
骨科
·
感染病学
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高影响因子
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