APPLIED OPTICS
·
2025
·Vol. 64
·期 19
·5593-5601
·
IF 1.7
Chenxi Wang,Siyu Wan,Deen Wang,Ruoyu Li,Zhiyang Jin,Alan R. Kost,Xiaolan Sun
Copper ions (${{\rm Cu}^{2 +}}$) play critical roles in biological systems but induce toxicity at elevated concentrations. This study, to our knowledge, reports a novel ratio-metric fluorescence sensor based on near-infrared (NIR)-emissive PbS quantum dot (QD)-doped hydrogel fiber sensor for real-time, selective detection of ${{\rm Cu}^{2 +}}$. The sensor employs a biocompatible and mechanically flexible HF with a core-cladding structure to confine light within the core for efficient transmission. Densely silica-coated PbS QDs (Si-QDs, emission at 1000 nm) serve as a stable reference signal, while copolymer-functionalized PbS QDs (P-QDs, emission at 1300 nm) exhibit ${{\rm Cu}^{2 +}}$-specific fluorescence quenching via photoinduced electron transfer. By ratiometrically monitoring the dual emission intensities (${F} = {{I}_{1300}}/{{I}_{1000}})$, the sensor achieves quantitative ${{\rm Cu}^{2 +}}$ detection with a linear range of ${0 {-} 100}\;\unicode{x00B5}{\rm M}$ and a limit of detection of 1.57 µM, effectively mitigating environmental interference. This work synergistically integrates the biocompatibility of hydrogels with the deep tissue penetration advantages of the NIR window. It has been preliminarily tested in laboratory environments, establishing a foundational platform for future-deep tissue implantable sensors.
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DOI
PubMed
高影响因子
Small
·
2025
·
IF 12.1
Deguang Ji,Zi Yang,Yaxiong Yao,Yichao Hou,Zidong He,Pengfei Da,Wei Shen,Li An,Yuanmiao Sun,Pinxian Xi,Chun-Hua Yan
Copper-based catalysts show considerable promise in the electrochemical CO 2 reduction reaction (CO 2 RR) for the production of hydrocarbons and oxygenates, particularly methane (CH 4 ), which is a highly reduced product. The high-valent state of copper (Cu) exerts a positive influence on the formation pathway of CH 4 , but the reduction potential will lead to a decrease in the valence state during CO 2 RR. In this study, a highly crystalline and structurally well-defined Y 2 Cu 2 O 5 catalyst is constructed to stabilize Cu 2+ with the orderly alternating Y─O skeleton layer, owing to the strong bonding interaction. The Y 2 Cu 2 O 5 exhibits a remarkable enhancement in CH 4 selectivity compared to CuO (up to 9.59-folds), achieving a selectivity of 61.3% at 300 mA cm −2 and 58.4% at 400 mA cm −2 , together with good stability. In situ attenuated total reflectance Fourier transform infrared spectra (ATR-FTIR) and density functional theory (DFT) calculations reveal that the presence of the Y─O skeleton layer in Y 2 Cu 2 O 5 significantly enhances the adsorption of *CO intermediate, and accelerates its hydrogenation process, facilitating the conversion of CO 2 to CH 4 . This work highlights Y─O skeleton-mediated stabilization of Cu 2+ for efficient electroreduction of CO 2 to CH 4 , providing valuable insights into the design of efficient electrocatalysts for CO 2 conversion.
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DOI
PubMed
高影响因子
PLoS One
·
2014
·Vol. 9
·期 3
·e93000
·
IF 3.534
Hao Cai,Zhiyong Xie,Guanghui Liu,Xiuman Sun,Guangtian Peng,Baoqin Lin,Qiongfeng Liao
Reactive oxygen species leads to some diseases associated with oxidative stress. Callicarpa kwangtungensis Chun (CK) is a common remedy in traditional Chinese medicine and possesses diverse biological activities involving antioxidant properties; its main compounds phenylethanoid glycosides (PG) and flavonoids are always reported as antioxidants. In order to develop CK as a safe and activated antioxidant, our investigation was performed to validate antioxidant properties and assess which types of compounds (similar polarity or similar structure), even which compounds, played the role of antioxidants. The extracted compounds of CK were analyzed qualitatively and quantitatively by HPLC-DAD-ESI-Trap MS and UV for their contents and antioxidant activities. The correlations between antioxidant activities and known contents were respectively counted and a semi-quantitative experiment was designed to screen antioxidant compounds of CK with HPLC-UV. The n-butanol fraction (BF) showed the highest total phenolic and flavonoid contents (TPC, TFC), and three PG (forsythiaside B, poliumoside and acteoside) contents. BF showed the significantly best ( P <0.05) activities in most assays. There were significant correlations ( P <0.05) between DPPH•, ABTS + •, •O 2 − scavenging, Cu 2+ -chelating, anti-lipidperoxidation activities and TPC. BF also has significant antioxidant activities on CCl 4 -induced acute liver injury Mice and TBHP-reduced HepG2 cells. Nine PG (forsythiaside B, poliumoside, acteoside, alyssonoside, brandioside and their derivatives) and one flavone (rhamnazin) were screened out as antioxidants. BF in CK contained abundant polyphenolic, which reflected some definite antioxidant properties. The antioxidant compounds consisted at the least of nine PG and one flavone.
研究领域:
药理学
·
植物化学
·
中药学
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DOI
PubMed
高影响因子
Journal of Inorganic and Organometallic Polymers and Materials
·
2025
·
IF 4.9
Guo Yuxiang,Zhu Jingyun,Sun Changge,Li Yubao,Li Tian,Liu Chao,Wang Qi
Carbon dots (CDs) are suitable for metal ion detection owing to their distinct optical tunability, structural controllability, and varied fluorescence response mechanisms. This research produced blue-fluorescent carbon dots (B-CDs) and red-fluorescent carbon dots (R-CDs) by a one-step microwave-assisted technique. B-CDs specifically recognized Cu 2+ in an aqueous system, while R-CDs exhibited a distinctly selective response to Fe 3+ . Composite carbon quantum dots (B/R-CDs) with purple fluorescence were synthesized by integrating B-CDs and R-CDs, achieving superior dual-metal ion detection capabilities. Using B/R-CDs with dual fluorescence emission peaks, and by monitoring the changes in their ratio fluorescence signals, the designed ion detection system can simultaneously detect Cu 2+ and Fe 3+ in aqueous solutions. The detection process for the two metal ions corresponds to distinct dynamic quenching behaviors of the B/R-CDs. Specifically, Cu 2+ and Fe 3+ form unique coordination structures with the functional groups of the B/R-CDs, leading to different energy level arrangements. This not only enables the discriminative detection of the two metal ions by the B/R-CDs but also ensures immunity from interference by other metal ions. The synthesized dual-emissive B/R-CDs material can be prepared as a single reagent for the quantitative detection of two trace metal ions. Furthermore, test strips and test inks developed with it as the primary component enable semi-quantitative and visual detection.
研究领域:
材料科学
·
分析化学
·
纳米技术
·
环境监测
·
传感器与生物传感器
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DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2015
·
IF 2.711
Xiaoyong Zhang,Qiang Huang,Meiying Liu,Jianwen Tian,Guangjian Zeng,Zhen Li,Ke Wang,Qinsong Zhang,Qing Wan,Fengjie Deng,Yen Wei
The environmental applications of carbon nanotubes (CNTs) have attracted great research attention since their first discovery. However, the performance of pristine CNTs for removal of heavy metal ions is greatly limited by their severe aggregation and lack of functional groups. In this work, a novel method has been developed for preparation of amine functionalized CNTs via combination of mussel inspired chemistry and Michael addition reaction. CNTs were first coated with polydopamine (PDA) through mussel inspired chemistry. And then commercial available agent polyethylene polyamine with a number of amine groups was further conjugated with PDA coated CNTs via Michael addition reaction. A series of characterization techniques have demonstrated that the amine functionalized CNTs have been successfully prepared. Furthermore, the adsorption application of thus amine functionalized CNTs for Cu 2+ was examined. The effects of various parameters including pH solution, temperature, initial Cu 2+ concentration and the adsorbent concentration were investigated. The data from experiments were analyzed by the Langmuir and Freundlich models of adsorption. Due to the universal of mussel inspired chemistry, the method described in this work should be a general strategy for surface modification of materials for environmental applications.
研究领域:
环境科学
·
材料科学
·
化学工程
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DOI
高影响因子
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
·
2020
·Vol. 36
·期 6
·1039-1044
·
IF 1.063
Gu Xianmo,Ma Pengwei,Liu Pei,Wang Ruiyi,Li Xincheng,Zheng Zhanfeng
A new type of activated carbon immobilized copper(Cu/AC) photocatalyst was prepared by a facile impregnation-adsorption method, where Cu 2+ is chemically adsorbed by abundant oxygenated functional groups on large-surface-area activated carbon surface. Cu/AC exhibited good activity and selectivity to imine for the hydroamination of alkynes at 60 °C under visible light irradiation. The reaction is initialized by the activation of alkynes molecules at Cu active sites with the aid of light as evidenced by the solid-state NMR and laser photolysis measurements and the control experiments. This strategy for catalyst design is potentially extended to the immobilization of other metal homogeneous catalysts for various heterogeneous catalytic systems.
研究领域:
催化化学
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材料科学
·
有机合成
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DOI
高影响因子
Materials Advances
·
2021
·Vol. 2
·期 10
·3346-3352
·
IF 0
Ying Li,Dan Liu,Ya-Qi Wang,Fang-Fang Wang,Han-Xun Qiu
In this study, we developed a novel flexible method to construct a lanthanide dual-emitting ratiometric fluorescence nanoprobe with excellent luminescence properties and significant selectivity for the detection of copper ions, where the central Eu3+ ions are coordinated with 2,6-pyridinedicarboxylic acid (DPA) on the surface of CQDs. The structure and chemical sensing photoluminescence properties of the as-prepared fluorescent probe have been investigated in detail. Moreover, the results have shown that Eu-DPA–CQDs exhibit two fluorescence emissions at 450 nm and 613 nm, respectively, under an excitation wavelength of 285 nm. The responses of the two emissions towards Cu2+ ions are completely different and can provide references for each other. Therefore, it can be designed as a fluorescence sensor for the detection of Cu2+ ions. The emission spectrum at 613 nm is markedly quenched, while that at 450 nm slightly changed after the addition of Cu2+ ions. When the Cu2+ ion concentration was 0–150 μM, the FL ratio (IEu/ICQDs) showed a good linear relationship with the lowest detection limit (LOD) of 6 nM. Thus, the reported sensor has a high selectivity, satisfactory accuracy and precision, and it may provide the potential application in the biological and environmental fields.
研究领域:
材料科学
·
分析化学
·
环境科学
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DOI
ENVIRONMENT INTERNATIONAL
·
2019
·
IF 7.943
Lianqin Zhao,Xin Guan,Baowei Yu,Na Ding,Xinmei Liu,Qiang Ma,Shengnan Yang,Ailimire Yilihamu,Sheng-Tao Yang
Due to the strong interaction with pollutants and the huge adsorption capacity, graphene adsorbents are widely applied in water decontamination. However, graphene adsorbents are seldom used in soil remediation, because the adsorptive sites on graphene would be occupied by soil components. In this study, we prepared carboxylated graphene oxide-chitosan (GO-COOH/CS) spheres for the immobilization of Cu 2+ from water and soil. The pores in GO-COOH/CS allowed the internal diffusion of Cu 2+ solution, while they blocked the direct contact between the solid soil and the adsorptive sites on graphene sheets. Therefore, the high adsorption capacity of GO-COOH/CS spheres (78 mg/g) was largely retained for the soil Cu 2+ fixation. The partition coefficient (PC) for Cu 2+ adsorption onto GO-COOH/CS spheres was 4.2 mg/g/μM at C e of 0.48 mg/L and q e of 31 mg/g, while the PC value decreased to 0.096 mg/g/μM at C e of 91.4 mg/L and q e of 78 mg/g. At initial Cu 2+ concentrations of 120 mg/L and lower, the fixation efficiencies were all higher than 99% and the corresponding free Cu 2+ concentrations in leachates were lower than 1.0 mg/L. The Cu 2+ fixation on GO-COOH/CS spheres largely reduced its bioaccumulation in wheat roots from 127.8 μg/g to 51.2 μg/g. The toxicity evaluations suggested that GO-COOH/CS spheres were of low toxicity to wheat seedlings and did not amplify the toxicity of Cu 2+ . The implications to the design of graphene adsorbents for soil remediation are discussed. Overall, our results collectively indicated that porous GO-COOH/CS spheres were high-performance adsorbents for the immobilization of Cu 2+ to reduce Cu 2+ bioaccumulation in plants.
研究领域:
环境科学
·
农业科学
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DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2016
·
IF 4.758
Shi Gang Liu,Na Li,Yu Zhu Fan,Nian Bing Li,Hong Qun Luo
We have demonstrated a fluorescence approach for rapid, environment-friendly, and selective detection of Cu 2+ in aqueous media using a kind of easily prepared and autofluorescent polymer nanoparticles (PNPs) as a sensor. The PNPs were synthesized by crosslinking hyperbranched polyethyleneimine (hPEI) with formaldehyde in water solution, and they emitted strong intrinsic fluorescence without the conjugation to any external fluorescent agent. The Cu 2+ assay was on the basis of the principle that Cu 2+ can be adsorbed on the surface of the PNPs, resulting in the fast and remarkable fluorescence quenching through electron transfer. The developed sensor was applied to the analysis of copper ions in environmental water samples with satisfactory results. Furthermore, the fluorescence of the PNPs-Cu 2+ system can restore upon addition of cysteine (Cys) because of its ability to remove Cu 2+ from the surface of PNPs. Based on the fluorescence “on-off-on” conversion, a reversible IMPLICATION logic gate was designed by using Cu 2+ and Cys as the two inputs, and fluorescence intensity of the PNPs as the output signal.
研究领域:
分析化学
·
材料科学
·
生物传感
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DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2015
·
IF 5.636
Limin Zhang,Yingying Han,Fan Zhao,Guoyue Shi,Yang Tian
Metals are essential components of all living cells, and in many cases cells trigger and utilize dynamic metal movements for signaling purposes. So, it is very critical to develop the biosensors for determination of metal ions in living systems with high selectivity and accuracy. In this work, taking Cu2+ as a model, an accurate and selective ratiometric electrochemical biosensor was developed. First, the specific molecule, 2,2′,2″-(2,2′,2″-nitrilotris(ethane-2,1-diyl)-tris((pyridin-2-ylmethyl)azanediyl)triethanethiol (TPAASH), was designed and synthesized for specific recognition of Cu2+. Meanwhile, electroactive molecule, 6-(ferrocenyl)hexanethiol (FcHT) was coimmobilized with TPAASH at one electrode as inner reference molecule to provide a built-in correction for avoiding the environmental effects. Thus, the developed biosensor demonstrated high accuracy and remarkable selectivity toward Cu2+ against other metal ions, amino acids, and so on. In addition, the biosensor also showed high sensitivity due to the electrocatalytic activity of the nanostructured gold flowers. As a result, the present ratiometric electrochemical biosensor was successfully applied in detection of Cu2+ in brain microdialysates of normal rat brain and that followed by global cerebral ischemia.
研究领域:
生物传感技术
·
神经科学
·
分析化学
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DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Dongjian Zhu,Aishan Ren,Xingcun He,Yanghe Luo,Zhenhua Duan,Xiaowei Yan,Yuhao Xiong,Xing Zhong
A novel hemicyanine-based ratiometric fluorescent probe 3 for Cu 2+ was described. The probe exhibited fluorescence emission at 448 nm. Upon addition of Cu 2+ , the emission at 448 nm quenched and simultaneously generated a significant bathochromic shift of the emission maximum to 503 nm due to the Cu 2+ -triggered hydrolysis reaction of the picolinate moiety. Thus, a single-excitation, dual-emission ratiometric measurement with a large red shift in emission (Δ55 nm) and remarkable changes in the ratio (F 503nm /F 448nm ) of the emission intensity (R/R 0 up to 22-fold) could be established. Moreover, the probe exhibited a large Stokes shift, high sensitivity (detection limit of 1.1 nM), and high selectivity for Cu 2+ over other metal ions in complete aqueous solution.
研究领域:
分析化学
·
生物化学
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DOI
高影响因子
CRYSTENGCOMM
·
2022
·Vol. 24
·期 45
·7962-7970
·
IF 3.756
Meng Li,Jingtao Xu,Yang Song,Feiyong Chen
Although various cations have been explored as a substitute for Pb2+ in CsPbX3 nanocrystals (NCs), there has been little research to study the influence of the doping methods on the doping results. Cu2+ is one such candidate as a transition metal with low toxicity, yet there are limited studies on Cu2+-doped CsPbX3 NCs, especially on the effect of the doping methods. Herein, Cu2+ was successfully doped into CsPbBr3 NCs with the replacement of Pb2+via a hot-injection method and postsynthetic cation-exchange reaction. Using the hot-injection method, the introduction of additional Cu2+ promoted the formation of CsPbBr3 nanoplates with a uniform thickness. The size of the CsPbBr3 nanoplates increased with the increase in the temperature. Differently, using the postsynthetic cation-exchange reaction, doping moderate Cu2+ ions into CsPbBr3 NCs evidently improved the PLQY, prolonged the PL lifetime, and decreased the non-radiative decay, resulting from an effective passivation of the surface defects on CsPbBr3 NCs. The different effect of Cu2+ was the outcome of how the CuBr2 interacted with the CsPbBr3 NCs in the different protocols. Our results should promote further research on the substitution of Pb2+ with other cations, providing effective protocols to prepare low-dimensional CsPbBr3 nanoplates with a uniform thickness and easily controlled lateral size, and can achieve an enhancement of the PLQY of CsPbBr3 NCs, which will benefit the further development of CsPbX3 in optoelectronic and other fields.
研究领域:
材料科学
·
光学
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DOI
高影响因子
危险品化学品经营许可证（带存储）