JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2018
·
IF 3.412
Chunxu Chen,Guijie Chen,Peng Wan,Dan Chen,Tao Zhu,Bing Hu,Yi Sun,Xiaoxiong Zeng
The protein–polyphenol layer by layer (LbL) assembled polymer composite microcapsule is a considerable delivery system that can be used to improve the bioactive stability and effectiveness of natural compounds in various applications. In the present study, three kinds of polyphenols were loaded in the sequence of (−)-epigallocatechin gallate (EGCG), 3,4-O-dicaffeoylquinic acid (3,4-diCQA), and tannin acid (TA) to prepare a BSA–polyphenol LbL membrane. The composition of IgG-(BSA-EGCG/3,4-diCQA/TA)n microcapsules and their stability and releasing ability in the gastrointestinal tract were evaluated. In addition, by binding of these three kinds of polyphenols to BSA, the thermal denaturation temperature and ordered secondary structure of the BSA–polyphenol microcapsules were increased, and the time of scavenging activity on 2,2′-azinobis(3-ethylbenzothiazolin-6-sulfonic acid) free radicals was significantly prolonged. These findings suggest that (BSA-EGCG/3,4-diCQA/TA)n microcapsules can not only protect IgG in food processing and stomach digestion but also release it in the small intestinal tract for bioactive delivery.
研究领域:
食品科学
·
生物化学
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DOI
PubMed
高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2024
·Vol. 59
·期 8
·3573-3584
·
IF 3.5
Xu Man,Luo Yongping,Zeng Linsheng,Huang Ping,Xu Shunjian,Liu Yike,Wang Yongya,Li Xianchang,xie Yu
In consideration of the increased activity of Pt-based catalysts for methanol oxidation in direct methanol fuel cells, it is necessary to apply an ideal support in the construction of Pt-based catalyst for methanol oxidation. In this study, Ag/g-C 3 N 4 nanosheets (Ag/GCNN) nanocomposites with different Ag contents were synthesized and used as the progressive support to construct Pt/Ag/GCNN catalyst. As a nitrogen-rich polymeric semiconductor, GCNN is easily coordinated with various metals. The introduction of Ag nanoparticles can improve the electrical conductivity of the catalyst and cooperate with Pt for optimizing the performance of electrocatalytic oxidation of methanol. The electrochemical experiment results demonstrated that Pt/Ag/GCNN has higher electrocatalytic activity and stability for methanol oxidation than Pt/GC and Pt/GCNN. The mass activity of Pt/Ag/GCNN-0.6 (18.66 mA mg Pt −1 ) is 7.07, 4.60 and 1.26 times that of Pt/GCNN (4.06 mA mg Pt −1 ), Pt/Ag/GCNN-0.4 (4.06 mA mg Pt −1 ) and Pt/Ag/GCNN-0.8 (14.76 mA mg Pt −1 ) at the forward peak potential. The J f / J b ratio of Pt/Ag/GCNN-0.6 is 3.31, which is bigger than that of Pt/GCCN (2.62), Pt/Ag/GCNN-0.4 (2.69), and Pt/Ag/GCNN-0.8 (2.56). A suitable mechanism was proposed to explain that Ag/GCNN supported Pt catalyst can improve the CO toxicity resistance and electrocatalytic performance. Based on the coordination of GCNN, Ag was first modified to form a support, and then the remaining coordination sites were used to support Pt. It provided a new strategy for the design of catalysts for methanol electrooxidation. Graphical abstract
研究领域:
材料科学
·
电化学
·
催化
·
纳米技术
·
能量转换
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Xinyu Du,Xue Bai,Lu Xu,Lei Yang,Pengkang Jin
A novel TiO 2 /g-C 3 N 4 -PS system was proposed, in which a TiO 2 /g-C 3 N 4 heterojunction was used to activate persulfate (PS) to enhance pollutant photodegradation under visible-light irradiation. In this study, the TiO 2 /g-C 3 N 4 photocatalyst was synthesized by a simple calcination method, and acetaminophen (AAP) was chosen as a model pollutant to test the degradation efficiency of the photocatalytic system. The TiO 2 /g-C 3 N 4 -PS system exhibits an efficient activity for PS activation and a high efficiency for pollutant degradation . The results show that 100 mL of a 5 mg/L AAP solution could be almost completely degraded in 30 min with 0.5 g/L photocatalyst and 2 mM PS, and TOC can be decreased by 82.5% in 60 min. After adding PS, the degradation rate of the TiO 2 /g-C 3 N 4 photocatalytic system was greatly improved by nearly 13 times, compared to the TiO 2 /g-C 3 N 4 system. The radical quenching experiments and electron paramagnetic resonance (EPR) results indicate that SO 4 − , OH and h + all contribute to eliminating organic compounds. Additionally, the TiO 2 /g-C 3 N 4 -PS photocatalytic system was employed to eliminate other typical micropollutants, such as phenol , bisphenol A and carbamazepine, and experiments were also carried out using real water matrices, and the ideal performance shows that the TiO 2 /g-C 3 N 4 -PS photocatalytic system has a strong nonselective oxidative ability for degrading contaminants.
研究领域:
环境科学
·
化学
·
材料科学
·
水处理
✓ 已验证
DOI
高影响因子
NANO
·
2023
·
IF 1.2
Chen Wang,Lu Gan,Yuxuan Li,Shan Wang,Li Lu,Siyao Zhang,Wenrui Wang,Yan Chen
Graphite carbon nitride (g-C 3 N 4 ) polymer with two-dimensional planar structure is a new star in nanodrug delivery systems in recent years because it shows characteristics of low cost, nontoxicity, biocompatibility and easy functionalization. However, conventional g-C 3 N 4 shows bulk, macro size, small specific surface area and poor water solubility. To improve this, most works are always confined to physical ultrasound, oxidative peeling or template-strategy, which have the disadvantages of redundant steps, environment-unfriendliness and high cost. In this paper, a modified supramolecular self-assembled strategy was carried out to construct a novel graphitic carbon nitride nanoplatform (named by CA-MA X ) using melamine and cyanuric as precursors. The chemical structure characterization, drug loading experiment and cell tests in vitro of the CA-MA X nanoplatform were carried out and discussed in detail. Results indicated that the obtained samples show enhanced specific surface area, more exposed groups and good biocompatibility. Compared to the traditional carbon nitride (named by MA-CN), the newly prepared CA-MA X carrier shows improved drug loading efficiency and good pH-responsive loading, as well as releasing. Cell uptake experiment demonstrates that CA-MA 2 -DOX can be swallowed by cancer cells and during treatment of the cancer cell process, the CA-MA 2 -DOX complex experiences phagocytizing by the cancer cell, controlled-release DOX and kills the cancer cell after DOX was passively diffused into the nucleus. CA-MA 2 -DOX exhibited significant in vitro antitumor activity. To our knowledge, this is the first time the supramolecular self-assembled method was used in carbon nitride nanocarrier construction for cancer treatment.
研究领域:
纳米技术
·
材料科学
·
药学
·
生物医学工程
·
肿瘤学
·
化学合成
✓ 已验证
DOI
高影响因子
JOURNAL OF SEPARATION SCIENCE
·
2022
·Vol. 45
·期 19
·3754-3762
·
IF 3.614
Zixin Chi,Xi Wu,Qiqi Zhang,Fengyang Zhai,Zesheng Xu,Dandan Zhang,Qing Chen
Titanium-based metal-organic framework MIL-125(Ti) was synthesized by the hydrothermal method of terephthalic acid and tetra butyl titanate in N-N ,dimethylformamide, and methanol. MIL-125(Ti) was characterized by Fourier-transform infrared spectroscopy, X-ray diffraction, thermogravimetric analysis, nitrogen adsorption-desorption, energy-dispersive X-ray spectroscopy, zeta potential, scanning electron microscope, and transmission electron microscopy. The results showed MIL-125(Ti) could be used as a potential adsorbent for protein separation and purification due to the high specific surface area, high stability, and strong hydrophobicity. As a result, MIL-125(Ti) had adsorption selectivity for immunoglobulin G, which was due to the hydrogen bond between MIL-125(Ti) and protein. At pH 8.0, the maximum adsorption efficiency of 0.25 mg MIL-125(Ti) for 300 μL 100 μg/mL immunoglobulin G was 98.3%, and its maximum adsorption capacity was 232.56 mg/g. The elution efficiency of immunoglobulin G was 92.4% by 0.1% sodium dodecyl sulfate. sodium dodecyl sulfate-polyacrylamide gel electrophoresis result demonstrated the successful isolation of highly purified immunoglobulin G from the human serum. Therefore, a new method of separation and purification of immunoglobulin G in human serum using titanium-based metal-organic framework MIL-125(Ti) as a solid-phase adsorbent was established, which broadened the application scope of metal-organic frameworks.
研究领域:
化学
·
生物化学
·
材料科学
✓ 已验证
DOI
PubMed
高影响因子
Microsystems & Nanoengineering
·
2024
·Vol. 10
·期 1
·1-16
·
IF 7.3
Yang Shuo,Li Kaiyue,Huang Ping,Liu Keyan,Li Wenhui,Zhuo Yuquan,Yang Ziwen,Han Donglai
This study introduces a multifunctional device based on Cu 2 O/g-C 3 N 4 monitoring and purification p–n heterojunctions (MPHs), seamlessly integrating surface-enhanced Raman scattering (SERS) detection with photocatalytic degradation capabilities. The SERS and photocatalytic performances of the Cu 2 O in various morphologies, g-C 3 N 4 nanosheets (NSs) and Cu 2 O/g-C 3 N 4 MPHs with different g-C 3 N 4 mass ratios were systematically evaluated, with a particular emphasis on the Cu 2 O/g-C 3 N 4 -0.2 MPH, where g-C 3 N 4 constituted 20% of the total mass. Multiple optical and electrochemical tests revealed that the Cu 2 O/g-C 3 N 4 -0.2 MPH effectively enhances charge separation and reduces charge transfer resistance. The Cu 2 O/g-C 3 N 4 -0.2 SERS sensor exhibited a relative standard deviation (RSD) below 15% and achieved an enhancement factor (EF) of 2.43 × 10 6 for 4-ATP detection, demonstrating its high sensitivity and consistency. Additionally, it demonstrated a 98.3% degradation efficiency for methyl orange (MO) under visible light within 90 min. Remarkably, even after 216 days, its photocatalytic efficiency remained at 93.7%, and it retained an 84.0% efficiency after four cycles. XRD and SEM analyses before and after cycling, as well as after 216 days, confirmed the structural and morphological stability of the composite, demonstrating its cyclic and long-term stability. The excellent performance of the Cu 2 O/g-C 3 N 4 MPH is attributed to its Z-type mechanism, as verified by radical trapping experiments. The evaluation of the self-cleaning performance of the Cu 2 O/g-C 3 N 4 -0.2 SERS sensor demonstrated that its Z-scheme structure not only provides excellent self-cleaning capability but also enables the detection of both individual and mixed pollutants, while significantly enhancing the SERS signal response through an effective charge transfer enhancement mechanism.
研究领域:
材料科学
·
环境科学
·
分析化学
·
光催化
·
纳米技术
·
传感器技术
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Pin Chen,Siyuan Di,Xiaoqing Qiu,Shukui Zhu
In order to achieve excellent visible light photoactivity of TiO 2 , it is still urgently required to extend their optical absorption ability and improve the potential of charge separation and migration. Here we synthesized highly efficient visible-light-active catalysts F-TiO 2 /g-C 3 N 4 via a one-step-calcination method. Due to the synergic effect of ≡Ti−F, ≡Ti:F−H and the heterojunction, the obtained catalysts possess promising properties as highly efficient separation and migration of photoelectron-hole pairs. The prepared F-TiO 2 /g-C 3 N 4 heterojunction can be successfully applied to degrade the widely used flame retardants and antibiotics. More than 95% of tetrabromobisphenol A (TBBPA) was decomposed after light illumination for 120 min, and 98% of sulfamethazine (SMZ) was degraded for 60 min by F-TiO 2 /g-C 3 N 4 . Furthermore, a reasonable catalytic mechanism for the F-TiO 2 /g-C 3 N 4 catalysts was proposed. It could be seen that the active species •O 2 − , •OH, and h + played important roles in the photocatalytic process under visible light illumination.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
Catalysis Science & Technology
·
2021
·Vol. 11
·期 22
·7316-7325
·
IF 6.119
Chao Zhang,Hailian Bao,Xiaodi Chen,Xingliang Liu,Shiai Xu
Three typical arylamine organic dyes were covalently grafted onto g-C3N4 to form the resulting composites g-C3N4/TPA-CNCHO, g-C3N4/EtPTZ-CNCHO and g-C3N4/EtCz-CNCHO. They were synthesized by 1,3-dipolar cycloaddition with (E)-3-(4-(diphenylamino)phenyl)-2-formylacrylonitrile (TPA-CNCHO), (E)-3-(10-ethyl-10H-phenothiazine-3-yl)-2-formylacrylonitrile (EtPTZ-CNCHO), or (E)-3-(9-ethyl-9H-carbazol-3-yl)-2-formylacrylonitrile (EtCz-CNCHO) dyes. The experimental results show that arylamine organic dye moieties were successfully attached to g-C3N4, and this attachment can efficiently extend the light absorption area of pure g-C3N4 from approximately 460 nm to more than 650 nm. The obtained g-C3N4/TPA-CNCHO, g-C3N4/EtPTZ-CNCHO and g-C3N4/EtCz-CNCHO samples showed enhanced H2 evolution activity with photocatalytic H2 production rates that were approximately 105-, 93- and 67-fold that of pure g-C3N4. By combining the comprehensive analysis from experiments and density functional theory (DFT) calculations, a possible mechanism can be drawn: the introduced arylamine organic dye fragments attached to the surface of the g-C3N4 may acquire more light irradiation, and effective photoexcited carrier transfer from the donor dye fragments to the acceptor g-C3N4 could be achieved through the IFCT process. The results confirm that the covalent azomethine ylide bonds formed via 1,3-dipolar cycloaddition between the g-C3N4 and organic dye can truly enhance the photocatalytic H2 evolution rate of the obtained samples. It is believed that this kind of modification can be an effective strategy for achieving other kinds of functional organic dyes grafted onto g-C3N4 with highly efficient photocatalytic H2 activity.
研究领域:
材料科学
·
化学
·
光催化
·
能源材料
✓ 已验证
DOI
高影响因子
FOOD HYDROCOLLOIDS
·
2025
·
IF 12.4
Yingchun Song,Yuyu Teng,Yudi Chen,Jiahui Nie,Yajie Dong,Qianqian Fan,Junxiang Zhu,Hao Wu,Yongkai Yuan
Biofilm-state probiotics can effectively improve their tolerance in harsh environments. Previous studies have shown that calcium alginate is an effective carrier for promoting biofilm formation, but its mechanism is unclear. Here, we show that tuning alginate molecular weight (Mw) and mannuronic/guluronic (M/G) directs Lactobacillus rhamnosus GG (LGG) biofilm formation and gastrointestinal tolerance. Our key finding is that calcium alginate beads with low Mw and low M/G alginates produce denser biofilms and superior gastrointestinal tolerance. These formulations markedly improved LGG survival in simulated challenges (gastric acid: 0.02–0.28 log CFU/g loss; bile: 1.54–2.31 log CFU/g), outperforming free cells. Mechanistic analysis revealed that low Mw and low M/G alginate matrices, with larger specific surface area, pore size, and volume, enhanced quorum-sensing autoinducer-2 signaling and subsequent protective extracellular substance synthesis, thereby improving the gastrointestinal tolerance of biofilm-state LGG. Overall, the findings emphasized that controlling alginate structure provides a rational, material-based strategy for designing advanced probiotic or bioactive delivery systems.
研究领域:
微生物学
·
材料科学
·
食品科学
·
分子生物学
·
药剂学
·
生物材料
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2020
·
IF 4.65
Jiaying Li,Xiang Yu,Yi Zhu,Xionghui Fu,Yuanming Zhang
A novel 3D-2D-3D BiOI/porous g-C 3 N 4 /graphene hydrogel (BPG) composite photocatalyst was synthesized via a two-step hydrothermal method and shows a synergy of adsorption and photocatalysis . In comparison with bulk g-C 3 N 4 , 2D porous g-C 3 N 4 (pCN) exhibited not only shortened diffusion distance for photogenerated carrier transport but also large contact area for rapid interfacial charge separation. Nevertheless, the photocatalytic performance was far from satisfactory due to the poor light harvesting. Incorporating 3D flower-like BiOI with 2D pCN to form a heterojunction was found to be an efficiency way for improving light harvesting, while charge separation efficiency was also enhanced. 3D graphene hydrogel, in which the effective photocatalyst 3D-2D BiOI/pCN heterojunction was homogenously distributed, not only revealed excellent adsorption capability and bulk electron transfer but also provided simplicity of separation and recovery. Consequently, in static system, the degradation efficiency of methylene blue (MB) and the typical antibiotic levofloxacin hydrochloride (LVF) was 7.2 and 2.7 times as high as that for BiOI. In flow system, the pollutants could be constantly degraded without separation with the removal rates about 1.54 and 1.67 times higher than those of BiOI, which kept unchanged for 30 h. The construction of 3D-2D-3D BPG composite combined the excellent adsorption capacity of GH with the photocatalytic activity of BiOI/pCN heterojunction, resulting in a high removal efficiency towards pollutants. This work provided deep insight into design and fabrication of 3D hydrogel composites with excellent synergy of adsorption and photocatalytic properties.
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
ACS Applied Optical Materials
·
2023
·
IF 0
Xiaoya Bu,Yan-gai Liu,Ci’an Xie,Baochen Wang
The long-afterglow luminescent material Sr2MgSi2O7:(Eu, Dy) was combined with the photocatalytic material g-C3N4 to construct a type of Sr2MgSi2O7:(Eu, Dy)/g-C3N4 self-luminous photocatalytic composite. This overcomes the limitation that photocatalytic experiments can only be carried out under an external light source, and it provides a more flexible way to use photocatalytic technology in environmental purification. The morphology, structure, luminescence, and photocatalytic properties of the samples were investigated using a variety of advanced characterization techniques. The results show that the significant improvement in the photocatalytic performance is attributed to the formation of a Z-scheme heterojunction between the luminescent and photocatalytic materials and the promotion of the photocatalytic reaction by the properties of the long-afterglow luminescent material itself. A possible mechanism for the photocatalytic process of the composite is proposed, and it is speculated that the reason for the increased photocatalytic activity is internal electron transfer and electron–hole pair separation based on tests such as X-ray photoelectron spectroscopy and density functional theory calculations. This study provides a strategy for enhancing the photocatalytic activity of photocatalysts and achieving round-the-clock degradation of pollutants.
研究领域:
材料科学
·
环境净化
·
光催化
·
纳米技术
✓ 已验证
DOI
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2018
·Vol. 410
·期 29
·7645-7653
·
IF 3.307
Zhang Dong-Ping,Wang Ling-E,Liu Xiao-Ying,Luo Zhi-Hua,Zheng Lei,He Yun,Zhang Bo
A facile and feasible photoelectrochemical (PEC) immunoassay based on plasmon-enhanced energy transfer between gold nanoparticles (AuNPs) and CdS quantum dots (QDs)/g-C 3 N 4 nanosheets was developed for the ultrasensitive detection of lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ). To construct such a sensing platform, the immunosensor was prepared by immobilizing Lp-PLA 2 on a CdS QDs/g-C 3 N 4 -modified electrode. A competitive-type immunoreaction was utilized for Lp-PLA 2 detection, with AuNP-labeled anti-Lp-PLA 2 antibody used as the competitor. Introducing AuNPs with the specific antibody for the antigen target Lp-PLA 2 led to heavy quenching of the photocurrent of CdS QDs/g-C 3 N 4 due to the plasmon-enhanced energy transfer between AuNPs and CdS QDs. The quenching efficiency decreased with increasing target Lp-PLA 2 concentration. Under optimal conditions, the PEC immunosensor presented a good photocurrent response to the target Lp-PLA 2 in the dynamic linear range of 0.01–300 ng mL −1 , with a low detection limit of 5.3 pg mL −1 . Other biomarkers and natural enzymes did not interfere with response of this system. The reproducibility and accuracy of this method for the analysis of human serum specimens were evaluated, and the results given by the method developed here were found to closely correspond to the results obtained with commercial Lp-PLA 2 ELISA kits. Importantly, this protocol offers promise for the development of exciton–plasmon interaction-based PEC detection systems.
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研究领域:
分析化学
·
生物化学
·
纳米技术
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）