JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2024
·
IF 4
Xiaofang Li,Jinyan Li,Yongwei Feng,Liqiang Liu,Hua Kuang,Chuanlai Xu,Lingling Guo
Fumonisin Bs (FBs) are the most common toxic and carcinogenic substances found among naturally occurring contaminants of cereals. A group-specific monoclonal antibody (mAb) 2H7 was prepared that equably recognized fumonisins B 1 (FB 1 ), B 2 (FB 2 ), and B 3 (FB 3 ) with a half-maximal inhibitory concentration (IC 50 ) value for the three forms of 1.52, 2.93, and 3.85 ng/ml, respectively. On this basis, a fluorescent microsphere-based immunochromatographic strip (FM-ICS) was established for the rapid qualitative and quantitative detection of total FBs (FB 1 , FB 2 , and FB 3 ) in corn , wheat, and rice. A recovery test showed that the recovery of FM-ICS was 92.8–108.3% with coefficients of variation of 1.2–7.9%. This method has the same reliability as seen with liquid chromatography-tandem mass spectrometry. And the accuracy was further confirmed by certified reference materials. Therefore, it can be used for the detection of FBs in cereal samples.
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DOI
高影响因子
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
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2024
·
IF 2
Shanshan Tang,Jia Zhao,Chang Liu,Dezhi Huang,Jing Tian,Yi Yang
Coprinus comatus is an edible mushroom and its fermented product possesses antioxidant activity. In this study, to further enhance the antioxidant activity and improve the reusability of the strain, calcium alginate hydrogel was used as the carrier for embedding and immobilizing Coprinus comatus. The effects of CaCl2 concentration, sodium alginate concentration, microsphere diameter, and the amount of magnetic particle on the antioxidant activity of fermented products were investigated. The results showed that the magnetic immobilized microsphere prepared by 2.50% CaCl2, 2.00% sodium alginate and 0.50% Fe3O4 had the best fermentation antioxidant activity (EC50 was 0.43 ± 0.01 mg/mL) when the diameter was 5 mm, which increased by 24.56% compared to the initial activity. Besides, the microsphere showed strong reusability, the antioxidant activity was still better than the free strain after being used five times. This study not only enhanced the antioxidant activity of Coprinus comatus fermented product through immobilization, but also provided an effective method for microbial fermentation.
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DOI
PubMed
高影响因子
POLYMER
·
2024
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IF 4.1
Cuiqing Zhou,Long Ni,Junyu Lu,Haichao Meng,Yinfu Luo,Mei Liang,Huawei Zou
The development of efficient and multifunctional broadband microwave absorption (MA) materials is critical for military applications to cope with complex environments. Herein, polyimide (PI)/carbon nanotube (CNT) composite foams (PCCFs) were successfully fabricated by assembling CNT with PI via the microsphere foaming method, where gradient CNT allowed tunable electromagnetic parameters. Benefiting from the improved the impedance matching characteristics and microwave dissipation, PCCFs displayed a remarkable reflection loss value of −53.5 dB and an EAB that could be extended up to 13.5 GHz through thickness variation, encompassing almost all C, X and Ku bands. Furthermore, the composite foams exhibited outstanding mechanical property with a specific compressive strength up to 6.8 MPa/(g/cm 3 ), as well as low thermal conductivity (0.106 W/(m·K)) and excellent heat resistance, which are important references for the development of high-performance MA structural components for applications in extreme environments.
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Journal of Materials Chemistry A
·
2022
·Vol. 10
·期 26
·13895-13906
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IF 14.511
Xueting Zhao,Youyou Lan,Tingyuan Wang,Yuanyuan Jiang,Jiefeng Pan
The emerging solar steam generation technology enables an alternative water purification strategy, which shows great potential for alleviating the global energy and water crisis. The elaborate designs of interfacial photothermal materials play important roles in promoting solar steam generation. Herein, novel photothermal membranes with tailored hierarchical cactus-like microsphere networks are fabricated via multiple polyphenol-mediated complexation. The hierarchical cactus-like microsphere network exhibits bi-continuous, superwetting and photothermal functional features, which play critical roles in balancing solar-to-thermal and water-to-steam conversion. The tightly distributed hierarchical cactus-like microspheres simultaneously trap sunlight inside the porous network, and thus promote localized solar-to-thermal conversion. The bi-continuous porous and superhydrophilic microsphere network provides efficient water-transport/vapor-escape channels and facilitates water-to-steam conversion. These features endow the photothermal membrane with a high evaporation rate of 1.83 kg m−2 h−1 and a solar-to-vapor conversion efficiency of 95.2% under one sun illumination. The photothermal membranes are also demonstrated to produce clean water by seawater desalination and wastewater decolorization. Moreover, the universality of the proposed strategy to engineer hierarchical cactus-like microsphere network membranes provides a scalable and flexible platform for promising solar-powered water purification application.
研究领域:
材料科学
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环境工程
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太阳能技术
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水处理
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高影响因子
BIOMACROMOLECULES
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2018
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IF 5.738
Junhua Li,Xuequan Zhang,Mingying Zhao,Lihuang Wu,Kui Luo,Yuji Pu,Bin He
Nanoparticle- and microsphere-based drug delivery systems (DDSs) have attracted wide attention in cancer therapy; those DDSs that are responsive to tumor environment can selectively identify tumor and normal tissues and therefore have shown enhanced anticancer efficacy and alleviated systemic toxicity. Here, tumor-pH-sensitive polymeric microspheres, which are prepared by multiblock poly(l-lactide) with pH-sensitive acetal bonds in the backbone, are employed to efficiently load water-soluble anticancer drug doxorubicin hydrochloride (DOX·HCl, drug loading content: ∼10%). The pH-sensitive DOX-loaded hollow microspheres were in the size range 2–10 μm and exhibited acid-accelerated degradation of polymer matrix and drug release, and thereby efficient in vitro cancer cell inhibition. The microspheres were further intratumorally injected into breast-tumor-bearing mice, and the in vivo anticancer experiment showed that pH-sensitive DOX-loaded microsphere showed better antitumor efficiency and prolonged life-span than its counterpart that does not have pH-responsive property. Moreover, negligible organ toxicity, especially cardiotoxicity that generally exists in DOX-involved chemotherapy where DOX is administrated by intravenous injection, was observed for DOX-loaded microspheres. Hence, tumor-pH-sensitive polymeric microspheres have appeared to be a simple and efficient platform for delivering hydrophilic anticancer drug with excellent anticancer efficacy and low systemic toxicity.
研究领域:
药剂学
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肿瘤学
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生物材料学
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PubMed
高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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2022
·Vol. 23
·期 24
·16227
·
IF 6.208
Jizhou Zhao,Peng Lu,Tengteng He,Jing Huang,Shiao Zhang,Yan Liu,Yun Wang,Cheng Meng,Dingzhong Yuan
The development of adsorption materials which can efficiently isolate and enrich uranium is of great scientific significance to sustainable development and environmental protection. In this work, a novel phosphonic acid-functionalized magnetic microsphere adsorbent Fe3O4/P (GMA-MBA)-PO4was developed by functionalized Fe3O4/P (GMA-MBA) prepared by distill-precipitation polymerization with O-phosphoethanolamine. The adsorption process was endothermic, spontaneous and kinetically followed the pseudo second-order model. The maximum uranium adsorption capacity obtained from the Langmuir model was 333.33 mg g−1at 298 K. In addition, the adsorbent also had good acid resistance and superparamagnetic properties, which could be quickly separated by a magnetic field. XPS analysis showed that the adsorption of adsorbent mainly depended on the complexation of phosphonic acid group with uranium. This work offers a promising candidate for the application of magnetic adsorbents in the field of uranium separation and enrichment.Keywords:uranium elimination;magnetic polymer microsphere;phosphonic acid;radioactive water treatment
研究领域:
环境科学
·
材料科学
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PubMed
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2017
·Vol. 409
·期 13
·3337-3346
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IF 3.431
Fan Yu-Han,Zhang Shou-Wen,Qin Shi-Bin,Li Xiao-Shui,Zhang Yuan,Qi Shi-Hua
Alkyl moieties which can retain target analytes due to their lipophilicity are important in sample preparation. In this work, hexadecyl-functionalized magnetic core-shell microspheres (Fe 3 O 4 @SiO 2 -C 16 ) was successfully prepared by one-pot sol–gel method and used for magnetic solid-phase extraction of polychlorinated biphenyls (PCBs) in environmental water samples. Optimized preparation method was achieved by altering the adding moment of hexadecyl-silane. The resultant materials were systematically characterized by scanning electron microscope, transmission electron microscope, Fourier transform infrared spectroscopy, energy dispersive X-ray spectrometry, tensionmeter, and vibrating sample magnetometer. The results demonstrated that the optimized adsorbent exhibited core-shell structure, superparamagnetic (66 emu/g), and extremely hydrophobic (water contact angle of 122°) properties. To evaluate the extraction performance, the prepared material coupled with gas chromatography-triple quadrupole mass spectrometry (GC-MS/MS) was applied to determinate PCBs. The extraction conditions were optimized. Under the optimal conditions, the proposed method showed a good linearity range of 1–100 ng L −1 with correlation coefficients ( R ) of 0.9989–0.9993. Based on a signal-to-noise ratio of 3 and 10, the limits of detection (LODs) and limits of quantification (LOQs) were in the range 0.14–0.27 and 0.39–0.91 ng L −1 , respectively. The intra- and inter-day relative standard deviations (RSDs) were less than 9.06%. The absolute recoveries of PCBs in spiked real water samples were in the range of 75.17 to 101.20%. Additionally, reusability and batch-to-batch reproducibility of the resultant material were acceptable with RSDs less than 5.64 and 3.25%, respectively.
The synthesis procedure of Fe 3 O 4 @SiO 2 -C 16 and determination of PCBs in water sample 129 × 50 mm (300 × 300 DPI)
研究领域:
分析化学
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环境科学
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PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2020
·
IF 7.632
Yufu Yi,Peng Wang,Guorong Fan,Zongde Wang,Shangxing Chen,Ting Xue,Yangping Wen
A hierarchically porous carbon microsphere (PCM) with phosphorus doping (A-PCM) for an oxidase-like sensor and supercapacitor was prepared by the hydrothermal reaction using d-(+)-xylose as a carbon source, F127 as a pore expanding agent, and phosphoric acid as an activation agent. Phosphoric acid activation resulted in phosphorus doping that was beneficial to produce micropores. The introduction of F127 promoted the formation of large mesopores and macropores. In contrast with conventional PCMs, the prepared A-PCM demonstrated a large specific surface area of 1469.71 m2/g, distinctive adsorption and diffusion properties, best conductivity, and cycling stability, which enabled it to serve as a high-performance electrode material that displayed a high peak current response with about 130-fold enhancement compared with bare GCE, intrinsic oxidase-like characteristics, excellent electrocatalytic capacity for niclosamide in linear ranges from 0.3 to 100 μM with a low detection limit of 8.4 nM under the optimum operation conditions, and a high specific capacitance of 445.71 F/g at a current density of 1 A/g.
研究领域:
材料科学
·
分析化学
·
电化学
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高影响因子
NEW JOURNAL OF CHEMISTRY
·
2026
·
IF 2.6
Yan Wang,Zeqi Wang,Yang Liu,Wanxuan Li,Xiangrong Zhang
Quercetin exhibits distinct therapeutic effects on various dermatologic diseases, including atopic dermatitis (AD), which is the most prevalent inflammatory skin disease, and psoriasis. The present study is aimed at developing a gel composed of quercetin-loaded porous microspheres and evaluating its therapeutic efficacy in mice with DNFB (2,4-dinitrofluorobenzene)-induced AD. Carbomer, a high molecular weight, hydrophilic, non-toxic, and non-irritating cross-linked acrylic polymer, was utilized in the formulation. Gel formulations containing carbomer demonstrate excellent adhesive properties and exhibit sustained drug release over 24 hours in our study. Building on prior research, ethyl cellulose-based microspheres of quercetin were prepared using a quasi-emulsion-solvent diffusion method. These microspheres were then dispersed in Carbomer 934 to create the microsphere-containing gel. The effects of the quercetin porous microsphere gel on DNFB-induced AD in mice were assessed through the atopic dermatitis area severity index scoring, spleen index assay, histopathological analysis, and measurement of inflammatory cytokines. Results from the animal studies indicated that the quercetin porous microsphere gel exhibited therapeutic effects. This study demonstrates that the quercetin porous microsphere gel shows promise as a carrier for the topical administration of quercetin in the treatment of AD.
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高影响因子
Surfaces and Interfaces
·
2023
·
IF 6.2
Hedong Chen,Wenxia Hu,Dao Wang,Min Dong,Yecheng Qiu,Lin Liu,Haiqing Qin,Shaofeng Wang,Prayoon Songsiriritthigul,Fuming Chen,Xianhua Hou
The anchored Si on the graphite as anode has attracted enormous attention as a promising alternative to graphite in the high-performance lithium-ion batteries (LIBs). However, the limited Si load, huge volume expansion and structural instability seriously restrict the performance of LIBs. In this work, the robust Si-based microspheres with double protective layers of ultrafine graphite sheet (UGS) and carbon layer are fabricated in a large scale and low-cost. The Si loads up to 44.7 wt% in the abundant 3D interconnected nano-porous channels. Both of UGS and UGS/nano-Si display excellent fast discharge/charge properties, compared with bulk flake graphite (FG) and FG/nano-Si. UGS/nano-Si@C exhibits an excellent electrochemical behavior. The initial capacity is up high to 1431.1 mAh g −1 at 0.1 A g −1 and the capacity retention can be maintained at 82.5% after 300 cycles. The excellent electrochemical properties are mainly ascribed to the robust composite structure and 3D interconnected nano-porous channels, which are beneficial for the fast electron/lithium-ion transfer and the reduced volume change. The ultrafine graphite sheet also shortens the lithium-ion diffusion path . The feasible strategy of the enhancement of Si load, the improvement of electronic conductivity and structural stability of Si-C composites will be significant for the next-generation electrode fabrication of high-capacity LIBs.
研究领域:
材料科学
·
储能
·
电化学
·
纳米材料
·
锂离子电池
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高影响因子
MATERIALS RESEARCH BULLETIN
·
2026
·
IF 5.8
Wentong Su,Wei Zhang,Wenke Zhang,Yuantao Chen
This study used a solvothermal method to prepare chlorella microspheres (ZCS-Ch) loaded with carbon-hybridized, nitrogen-oxygen-doped Zn 0.3 Cd 0.7 S (ZCS) nanoparticles, employing Chlorella (Ch) as a biological template. The catalyst's morphology and structure were characterized using XRD, SEM, and XPS. Under simulated visible light, the catalyst effectively degraded Norfloxacin (NOR). Experimental results show that the photocatalytic activity of the nanocomposite is greatly enhanced. ZCS-Ch8 achieved a 92.3% NOR degradation rate within 1 h, with a degradation rate of 0.04198 min-1, which is 1.6 and 15.6 times higher than ZCS (0.02963 min −1 ) and Ch (0.00269 min −1 ) respectively. The increased photocatalytic activity was examined through photoelectrochemical characterization. The addition of Ch effectively promoted charge transfer of photogenerated carriers and reduced their recombination. Finally, radical scavenging experiments and electron spin resonance (ESR) techniques confirmed that superoxide radical (·O 2 - ) is the main active species. Additionally, the catalyst showed excellent cycling stability over five consecutive degradation tests.
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高影响因子
POLYMER COMPOSITES
·
2026
·
IF 4.9
Siqi Han,Jiabao Lang,Xin Shao,Manyi Huang,Xinru Li,Ruquan Jin,Yadong Jia
Hollow glass microsphere/epoxy (HGM/EP) composites are lightweight polymer composites for acoustic matching layers, but the smooth microsphere surface has weak compatibility with epoxy, causing interfacial gaps, aggregation, and unstable acoustic transmission. In this study, hexagonal boron nitride-decorated hollow glass microspheres (HGM@BN) were prepared through hydroxylation, amination, and electrostatic self-assembly, and then incorporated into epoxy resin. The modification was intended to regulate the filler–matrix interface rather than only adjust acoustic impedance. Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and scanning electron microscopy confirmed the stepwise surface modification and the attachment of boron nitride nanosheets onto the microsphere surface. Compared with pristine HGM/EP, the optimized HGM@BN-5/EP composite showed fewer interfacial defects, a longitudinal sound velocity of 2210 m s −1 , an acoustic impedance of 1.35 MRayl, an increase in glass transition temperature from 84°C to 105°C, and an increase in compressive strength from 78 to 120 MPa. When used as a matching layer in approximately 200 kHz air-coupled ultrasonic transducers, HGM@BN-5/EP increased echo peak-to-peak amplitude by about 60% and reduced maximum relative center-frequency drift from 6.0% to 2.7% over −20°C to 70°C. Gas-flow and wind-speed sensing tests further verified its functional acoustic value. These results show that HGM@BN offers an effective interface-regulation route for lightweight epoxy-based acoustic matching composites. Highlights Interfacial gaps around microspheres were visibly reduced. Glass transition temperature increased by 21°C. Compressive strength increased from 78 to 120 MPa. Echo amplitude increased by about 60%. Maximum center-frequency drift decreased from 6.0% to 2.7%.
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高影响因子
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