JOURNAL OF SEPARATION SCIENCE
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2019
·Vol. 42
·期 9
·1757-1767
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IF 2.516
Xiaoyong Zhao,Ge Ma,Datong Wu,Pengfei Cai,Yuanjiang Pan
In the present work, three hydrophilic ionic liquids based on the combination between imidazolium cations attached with ethylene glycol polymers of various lengths and hexafluorophosphate anion were designed and synthesized for the separation of polysaccharides. By employing dextran 100 kDa as model compound, the effects of ionic liquid content, solvent/anti-solvent volume, and temperature on its recovery efficiency were investigated systematically. The ability of these ionic liquids to precipitate dextran 100 kDa, increases with the elongation of ethylene glycol polymer chain. The established ionic liquid-based precipitation system was successfully applied to selectively precipitate polysaccharides from water extracts of three traditional Chinese medicines and the precipitation could be achieved in about 15 min. In addition, the different precipitation responses of acidic, neutral, and basic polysaccharides in the ionic liquid-based precipitation system and theoretical calculations both suggested that the selective precipitation of polysaccharides was probably mediated by interaction between ionic liquids and polysaccharides. The proposed strategy facilitated the isolation and purification of polysaccharides and may trigger a novel application of ionic liquids in carbohydrate research.
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PubMed
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2018
·
IF 2.829
Weiwei Liu,Shuangkun Zhang,Zhi Qiao,Qi Li,Xiaoyu Li,Haiqiao Wang
A series of PEG-based star polymers with hexa(eugenol) cyclotriphosphazene (HECTP) core and controlled number of PEG arms have been prepared in high yields via simple thiol-ene click reaction combining Dicyclohexylcarbodiimide/4-Dimethylaminopyridine (DCC/DMAP) esterification under very mild experimental conditions, and their potential for application as surfactants was investigated. The surface activities, including the critical micelle concentration (CMC) and surface tension at CMC, of the polymer aqueous solutions were studied. The results showed that PEG-based star polymers with two arms have good surface activities such as low surface tension (low to 36.1 mN/m), good emulsification ability, due to their structural features similar to Gemini surfactants . Whereas, the PEG-based star polymers with more than two arms exhibited very low CMC values (low to 0.004 mg/ml) and strong emulsification ability, therefore they could be utilized as surfactants to form high internal phase emulsions (HIPEs). Using these new PEG-based star polymers as surfactants, a very low surfactant concentration (0.01 wt %) was sufficient to form oil-in-water emulsions with long-term stability more than 6 months. Although further studies are necessary to clarify the interfacial properties , this work opens a new study field for this kind of important organic-inorganic hybrid materials.
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JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION
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2019
·Vol. 34
·期 4
·945-949
·
IF 0.605
Kang Jiaqing,Chen Wei,Yao Yuan,Jin Yanqiao,Cheng Xiansu,Lü Qiufeng
Cassava residue was liquefied by using ethylene glycol (EG), ethylene carbonate, propylene carbonate and polyethylene glycol (molecular weight: 400 g/mol) as the liquefaction reagent respectively at the temperature of 130–170 °C with sulfuric acid as the catalyst. The influences of liquefaction parameters, such as the type of liquefaction reagents, mass ratio of EG/cassava residue, liquefaction temperature and time on the properties of the products were discussed. The optimum liquefaction conditions were obtained when the mass ratio of EG/cassava residue was 6:1 ( w/w ), the liquefaction temperature was 150 °C, the liquefaction time was 3 h and the mass fraction of concentrated sulfuric acid/EG was 2.5wt%. The hydroxyl numbers and residue content of the liquefied products at optimal conditions were 1 137 mgKOH/g and 0.43%, respectively. FT-IR spectrum showed that the liquefaction product of cassava residue was polyether polyol and could be used to prepare polyurethane material or alkyd resins.
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IONICS
·
2024
·Vol. 30
·期 5
·2665-2676
·
IF 2.4
Li Xiaogang,Tu Huan,Wu Rui,Wang Zongnan,Zhou Yanhui,Zong Yujie,Lu Yaokang,Qian Li,Zhang Yixian,Song Siyu,Meng Chunfeng,Yuan Aihua
Aqueous zinc-ion batteries are considered promising energy storage devices due to their low cost, high capacity, and high safety. However, the application of aqueous zinc-ion batteries is subject to the limits of Zn anode reversibility, such as the formation of Zn dendrites, Zn anode corrosion, and hydrogen evolution reaction. In this study, we reported an electrolyte additive ethylene glycol monomethyl ether (MOE) with a modulated electrolyte solvation structure, which can suppress the growth of Zn dendrites and enhance the reversibility of Zn chemistry. The MOE molecular shows a higher electron cloud density of oxygen atoms, which enhances the strength of H–O covalent bonds. Therefore, MOE can break the interaction between H 2 O and H 2 O and the interaction between H 2 O and Zn 2+ . The solvation structure of Zn 2+ is optimized to improve the reversibility of the Zn anode. As a consequence, the reversibility of Zn plating/stripping is promoted by 20% MOE-modified electrolyte with high CE of 99.4% at the current density of 1 mA cm −2 , stably cycled for 2100 cycles. The Zn||Zn symmetrical cells can keep dendrite-free cycling for more than 4000 h in the same target electrolyte. In addition, the Zn||V 2 O 5 cell can exhibit excellent long cycling stability for over 1000 cycles even at 5 A g −1 with the reversible capacity of 100 mAh g −1 . This work provides a universal additive strategy to design versatile electrolytes for aqueous zinc-ion batteries.
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RSC Advances
·
2015
·Vol. 5
·期 110
·90904-90912
·
IF 3.84
Yueling Cao,Junwei Wang,Maoqing Kang,Yulei Zhu
Hydrogenolysis of glucose and cellobiose, used as the model feedstocks, over Ni–WO3/SBA-15 catalysts has been investigated to probe the influencing factors for the conversion of cellulose to ethylene glycol (EG). The conversion of glucose and cellobiose to EG showed different dependencies on reaction temperature; a lower reaction temperature was needed for the former. Additionally, the surface atomic ratio of W to Ni on the Ni–WO3/SBA-15 catalysts was the key factor for the product distribution. Both glucose and cellobiose had their own optimum W–Ni ratio for the production of EG, and the ratio of W to Ni for glucose was slightly lower than that of cellobiose. On the other hand, the Ni–WO3/SBA-15 catalysts were thoroughly characterized by N2 adsorption–desorption, X-ray diffraction (XRD), hydrogen-temperature programmed reduction (H2-TPR), X-ray photoelectron spectroscopy (XPS) and transmission electron microscopy (TEM). The results indicated that the reducibility of Ni–WO3/SBA-15 catalysts with high Ni loading was more similar to that of pure NiO. More importantly, the change of surface atomic content of Ni and W of Ni–WO3 catalysts with various Ni loadings resulted from the surface W species of the catalysts being gradually covered by Ni species with the increase of Ni loading.
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Acta Biomaterialia
·
2017
·
IF 6.319
Huicong Zhou,Huanjiao Sun,Shixian Lv,Dawei Zhang,Xuefei Zhang,Zhaohui Tang,Xuesi Chen
Traditional chemotherapy strategy exists undesirable toxic side-effects to normal tissues due to the low selectively to cancer cells of micromolecule cytotoxic drugs. One considered method to realizing the targeted delivery and increasing the specificity to tumor tissues of the cytotoxic drug is to transporting and discharging it through an environment-sensitive mechanism. In this study, a novel enzyme-sensitive polymer-doxorubicin conjugate was designed to delivery chemotherapeutic drug in a tumor-specific behavior and selectively activated in tumor tissue. Briefly, doxorubicin (DOX) was conjugated to carboxyl-terminated 4-arm poly(ethylene glycol) through a tetrapeptide linker, alanine-alanine-asparagine-leucine (AANL), which was one of the substrates of legumain , an asparaginyl endopeptidase that was found presented in plants, mammals and also highly expressed in human tumor tissues. Hereinafter, the polymer-DOX conjugate was termed as 4-arm PEG-AANL-DOX. Dynamic laser scattering (DLS) and transmission electron microscopy (TEM) measurements indicated that the 4-arm PEG-AANL-DOX could self-assemble into micelles in aqueous solution. Drug release and in vitro cytotoxicity studies revealed that the 4-arm PEG-AANL-DOX could be cleaved by legumain. Ex vivo DOX fluorescence imaging measurements demonstrated that the 4-arm PEG-AANL-DOX had an improved tumor-targeting delivery as compared with the free DOX·HCl. In vivo studies on nude mice bearing MDA-MB-435 tumors revealed that the 4-arm PEG-AANL-DOX had a comparable anticancer efficacy with the free DOX·HCl but without DOX-related toxicities to normal tissues as measured by body weight change and histological assessments, indicating that the 4-arm PEG-AANL-DOX had an improved therapeutic index for cancer therapy. Statement of Significance Herein we describe the construction of a novel tumor environment-sensitive delivery system through the instruction of a legumain-cleavable linkage to a polymer-DOX conjugate (4-arm PEG-AANL-DOX). This particular design strategy allows for polymer-DOX conjugates to be delivered in a tumor-specific manner and selectively activable in tumor microenvironment so that it can combine the advantages of tumor-specific delivery and tumor intracellular microenvironment-triggered release systems.
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RSC Advances
·
2016
·Vol. 6
·期 57
·51694-51702
·
IF 3.289
Wenwen Deng,Yufeng Lei,Shengwen Zhou,Anqiang Zhang,Yaling Lin
Polydimethylsiloxanes (PDMS) are soft materials with high elasticity and excellent biocompatibility, giving them high potential for widespread applications as biomaterials. However, the application of PDMS to wound dressing is limited due to its shortcomings, particularly its non-absorptive and poor adhesive properties. This work addresses these limitations in two ways: first, a hydrophilic and biocompatible polyethylene glycol (PEG) block was introduced to the PDMS main chain to obtain carboxyl acid terminated PDMS-b-PEG-b-PDMS copolymers (EPMDS–COOH2); second, EPMDS–COOH2 polymers were reacted with diethylenetriamine and urea via a two-stage route to obtain a novel supramolecular elastomer (ESESi) based on multiple hydrogen bond association. Compared with the supramolecular elastomer based on simple PDMS (SESi), the hydrophilicity, water-absorption rate, adhesive ability and rate of water vapor permeation were significantly improved, enhancing the properties of ESESi films for application to wound dressing. After fully evaluating the bio-compatibilities of ESESi films, a full-thickness dermal wound model was chosen to estimate the healing performance, and traditional vaseline gauze, SESi film and commercialized Tegaderm™ film were chosen as controls. The results confirmed that the ESESi polymer could promote the healing of a skin wound to some extent, mainly due to its improved absorption and adhesive properties.
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COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
·
2016
·
IF 3.719
Junjiu Gao,Jiang Zhu,Jingjing Luo,Jie Xiong
The application of electrospun nanofibrous scaffolds in tissue engineering is limited due to their small pore size which leads to the failure of cell infiltration into the scaffolds. Microporous silk fibroin (SF)/gelatin composite scaffolds with biological properties could be fabricated to mimic tissue structure for tissue engineering applications. This study aimed to present a simple method to fabricate the composite scaffolds which is based on the simultaneously electrospraying of microspheres and electrospinning of nanofibers. Different contents of polyethylene glycol (PEG) microspheres were embedded into the SF/gelatin nanofibrous membranes by varying the content of PEG microsphere. Furthermore, microspheres can be selectively leached, obtaining the single SF/gelatin nanofibrous scaffolds and retaining the hierarchical organization of the porous nanofibers. In conclusion, the multilevel microporous and nanofibrous composite scaffolds can be obtained by varying pump flow rate of electrospraying.
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CATALYSIS COMMUNICATIONS
·
2017
·
IF 3.33
Bo Xu,Zhiming Chen,Bing Han,Cuncheng Li
This work presents MIL-100(Fe) nanoparticles synthesized using glycol with uniform size and morphology. This is the first report of nanoscale MOFs material synthesized using glycol. The MIL-100(Fe) particles have been characterized by SEM, TEM, XRD and the results indicate that the MOFs particles show monodispersed nanospherical morphology. Photocatalytic study reveals that the MIL-100(Fe) nanospheres exhibit good oxidation ability of benzene to phenol under visible light irradiation with high selectivity.
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GREEN CHEMISTRY
·
2016
·Vol. 19
·期 3
·682-691
·
IF 8.506
Naixu Li,Yu Zheng,Lingfei Wei,Hongcheng Teng,Jiancheng Zhou
Although the conversion of cellulose to polyols is currently well-developed, the production of the considerably valuable ethylene glycol (EG) is still challenging. Reactions have long relied on the design of suitable catalysts to obtain a high selectivity and yield of EG. Herein, using well-shaped rectangular tungsten trioxide nanosheets as the substrate, we investigated the catalytic performances of various metal supported catalysts for the convertion of cellulose to EG. Results show that Ru/WO3 is more favorable for EG production, with the highest EG yield of 76.3% over the 1% Ru/WO3 nanosheet catalyst. Our characterizations and activity tests suggest that the embedding of Ru nanoparticles onto the WO3 nanosheets produces more W5+ active sites under the same reduction conditions (NaBH4 or H2), which act as Lewis base sites to promote the glucose retro-aldol condensation reaction. Moreover, the Ru/WO3 catalyst holds a portion of Ru in the form of amorphous RuOxδ+ phases, which could further increase the H+ released into an aqueous solution for cellulose hydrogenolysis. A possible catalytic mechanism for this hydrogenolysis process is accordingly proposed.
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JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY
·
2017
·
IF 1.591
Jianbin Qin,Guangcheng Zhang,Xuetao Shi
The monodisperse polystyrene (PS) microspheres were prepared by dispersion polymerization. The rheological properties of shear thickening fluid (STF) based on PS microspheres dispersing in polyethylene glycol with different concentrations were studied through the steady and oscillatory shear at different temperatures, respectively. All suspensions successively present the first shear thinning, the shear thickening, and the second shear thinning. The experimental results indicate that the shear thickening behavior of STF is controlled by the concentration of PS microspheres and temperature, as changed from continuous shear thickening (CST) to discontinuous shear thickening (DST) with increasing solid content or decreasing temperature. The STF is affected by shear rate, temperature, and the viscosity of the dispersed medium, and it is reversible absolutely and presents transient response ability. Both CST and DST behave as dilatancy. The PS microsphere aggregations formed under shear stress may result in the shear thickening in STFs.
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JOURNAL OF CHEMICAL THERMODYNAMICS
·
2016
·
IF 2.196
Shurui Xu,Shuanshi Fan,Haiyuan Yao,Yanhong Wang,Xuemei Lang,Pingping Lv,Songtian Fang
In this paper, the three-phase coexistence points are generated for multicomponent gas hydrate in methanol (MeOH) solution for (0.05, 0.10, 0.15, and 0.35) mass fraction and ethylene glycol (EG) solution for (0.05, 0.10, 0.15, 0.35, 0.40 and 0.55) mass fraction. The phase equilibrium curves of different system were obtained by an isochoric pressure-search method on high pressure apparatus. The phase equilibrium regions of multicomponent gas hydrate were measured using the same composition of natural gas distributed in the South China Sea. And the different concentration solutions were prepared based formation water. The experimental data were measured in a wide range temperature from 267.74 to 298.53 K and a wide range pressure from 4.22 MPa to 34.72 MPa. The results showed that the hydrate phase equilibrium curves shifted to the inhibition region in accordance with the increased inhibitor concentration. In addition, the equilibrium temperature would decrease about 2.7 K when the concentration of MeOH increased 0.05 mass fraction. Besides, the suppression temperature was 1.25 K with the 0.05 mass fraction increase of EG concentration in the range of 0.05 mass fraction to 0.15 mass fraction. While in high EG concentration region, the suppression temperature was 3.3 K with the same increase of EG concentration (0.05 mass fraction).
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