FOOD CHEMISTRY
·
2019
·
IF 5.399
Xiaodong Xu,Rui Xu,Qian Jia,Tao Feng,Qingrong Huang,Chi-Tang Ho,Shiqing Song
The volatile compounds of Volvariella volvacea mushroom were investigated by solvent assisted flavor evaporation (SAFE)/gas chromatography-mass spectrometry (GC–MS), gas chromatography-olfactometry (GC-O), odor activity value (OAV), combined with aroma reconstitution and omission. The results showed that a total of 63 compounds were detected after SAFE extraction. A total of 26 compounds were determined after GC-O and 17 compounds whose OAV greater than 1 were subjected to reconstitution and omission experiments. The results showed that dihydro-β-ionone, 1-octen-3-one, 1-octen-3-ol, γ-undecalactone, 3-octanol, 2-octanone, hexanal, 2-methylbutanal, camphene, carvone, 2-nonanone, and phenylacetaldehyde have been successfully identified as the key aroma compounds. More significantly, dihydro-β-ionone as a key aroma compound was first found in Volvariella volvacea mushroom.
研究领域:
食品科学
·
微生物学
✓ 已验证
DOI
PubMed
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2013
·
IF 2.672
Yuanyuan Yao,Long Zhang,Jingkun Xu,Xiaoqiang Wang,Xuemin Duan,Yangping Wen
A rapid, sensitive and enzymeless methyl parathion (MP) electrochemical sensor based on carboxylic acid-functionalized single-walled carbon nanotubes–β-cyclodextrin modified glassy carbon electrode (ƒ-SWCNT–β-CD/GCE) was successfully constructed for the trace analysis of MP in vegetable samples. Cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy were utilized to characterize the properties of the modified electrode. Experimental parameters such as preconcentration time, pH value, and the concentration of ƒ-SWCNT and β-CD were optimized. The proposed electrode displayed excellent electrocatalytic activity towards MP. The calibration curve for MP was obtained in both ranges of 0.002–0.02 μg mL −1 and 0.02–17.5 μg mL −1 , with a low detection limit ( S/N = 3) of 0.4 ng mL −1 after a very short preconcentration time for 80 s. The modified electrode exhibited fast current response, high sensitivity, good reproducibility, and satisfactory anti-interference ability, and also successfully employed for the trace analysis of MP in vegetables samples. Satisfactory results revealed that this proposed electrochemical sensor can provide a promising candidate for the trace analysis of MP in agricultural and environmental samples.
研究领域:
分析化学
·
环境科学
·
农业科学
✓ 已验证
DOI
高影响因子
POLYMERS FOR ADVANCED TECHNOLOGIES
·
2021
·Vol. 33
·期 2
·492-504
·
IF 3.665
Zhongyang Yao,Qiming Cao,Chenyang Li,Weiguang Gong,Xin Meng
In this article, a β-cyclodextrin(CD)/cardanol (CA) inclusion complex (IC) was fabricated by co-precipitation method, which was used to guarantee excellent thermal oxidative stability and environmental-response antioxidation releasing property of PLA. The results showed that CA was successfully immobilized into β-CD with a stoichiometric ratio of 1:1, and the immobilization inhibited the migrant of CA from PLA during storage, resulting in the enhancement of antioxidant life of CA in PLA. Thus, PLA stabilized by IC (PLA/IC) maintained higher oxidation onset temperature (OOT) and molecular weight after long-term thermal oxidative aging. Moreover, CA releasing comparison from PLA/IC and PLA stabilized by CA (PLA/CA) in food stimulant suggested that PLA/IC released CA faster than PLA/CA when PLA contacted with food stimulants due to the solubilization of β-CD for CA, which would induce the quicker antioxidation of CA in food. In a word, IC can make PLA with longer anti-oxidative stability during storage and quicker environmental-response antioxidation releasing property during usage, showing strong potential as an active food-packaging materials.
研究领域:
材料科学
·
食品包装工程
✓ 已验证
DOI
高影响因子
TALANTA
·
2018
·
IF 4.244
Miao Wang,Kun Su,Jing Cao,Yongxin She,A.M. Abd El-Aty,Ahmet Hacımüftüoğlu,Jing Wang,Mengmeng Yan,Sihui Hong,Shuibing Lao,Yanli Wang
Here, we developed a novel non-enzymatic rapid testing method for determination of organophosphate pesticide (malathion) in water. In principle, target molecule can block the Fluorescence resonance energy transfer (FRET) between chemical fluorescent probe (energy donor) and β-cyclodextrin-coated silver nanoparticles (@AgNP) (receptor). The effects of malathion on the dynamics of fluorescent probe and β-cyclodextrin@AgNP were evaluated and their properties were further characterized. The current methodology showed a good sensitivity of 0.01 μg/mL represented as a limit of detection (LOD) and the calibration curve was linear over the concentration range of 0.1–25 μg/mL. Recovery rate from water samples spiked at 3 different concentration levels (0.3, 0.4, and 0.6 μg/mL) showed satisfactory range between 83% and 101%.
研究领域:
分析化学
·
环境科学
·
农药检测
✓ 已验证
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2015
·
IF 4.504
Xiangli Zheng,Shan Liu,Xiaoxia Hua,Fangquan Xia,Dong Tian,Changli Zhou
ABSTRACT A new electrochemical sensor for determination of 2,4,6-trichlorophenol (2,4,6-TCP) was fabricated. The characterization of the sensor was studied by scanning electron microscopy, electrochemical impedance spectroscopy and cyclic voltammetry techniques. The electrochemical behavior of 2,4,6-TCP was investigated using cyclic voltammetry and differential pulse voltammetry at the HS-β-cyclodextrin (HS-β-CD)/gold nanoparticles (AuNPs) composite modified indium tin oxide (ITO) electrode. The results showed that the current responses of 2,4,6-TCP greatly enhanced due to the high catalytic activity and enrichment capability of composites. The peak current of 2,4,6-TCP increases linearly with the increase of the 2,4,6-TCP concentration from 3.0 × 10 −9 to 2.8 × 10 −8 M, with the limit of detection of 1.0 × 10 −9 . Further more, the modified electrode was successfully applied to detect the level of 2,4,6-TCP in tap water samples with excellent sensitivity.
研究领域:
分析化学
·
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
Food & Function
·
2025
·
IF 5.4
Shanshan Zhang,Yonggan Sun,Linlin Gao,Ziyi Zhang,Yongkang Yu,Dechang Xu,Shaoping Nie
The combination of probiotics and prebiotics has emerged as a promising strategy for managing ulcerative colitis (UC). Among these, β-glucan (BG) and Lactobacillus johnsonii have individually shown potential in alleviating colitis, with BG notably enriching L. johnsonii populations, suggesting a synergistic therapeutic potential when combined. This study investigates the protective effects of a novel synbiotic formulation, BG and L. johnsonii NSP009 (LJ), termed BGLJ, in a dextran sulfate sodium (DSS)-induced colitis mouse model. Our results reveal that BGLJ significantly mitigated DSS-induced weight loss, reduced the disease activity index, and alleviated intestinal inflammation and barrier dysfunction. Notably, BGLJ markedly increased L. johnsonii abundance in mouse feces, with LJ producing substantial levels of indole-3-lactic acid (ILA), an aryl hydrocarbon receptor (AhR) agonist. BGLJ treatment robustly elevated ILA levels in the gut, activating AhR and upregulating IL-22 production. Collectively, our findings highlight the therapeutic potential of the BGLJ-based synbiotic in maintaining intestinal homeostasis and underscore its promise as a novel intervention for UC management.
研究领域:
消化病学
·
微生物组学
·
免疫学
·
分子生物学
·
营养学
·
转化医学
✓ 已验证
DOI
PubMed
高影响因子
Natural Product Communications
·
2024
·
IF 1.5
Jing Wang,Yuqian Yang,Wenxin Wei,Xingyu Li,Feng Liu,Jianshu Liu,Wei Lan,Feng Gao,Hong Wang,Peifeng Wei
Background: Osteoporosis has emerged as a significant global public health concern, predominantly affecting postmenopausal women. Its pathogenesis is intricate and the disease course is protracted, imposing substantial medical burden on both society and individuals. Objective: To investigate the effects of 2,3,5,4′-tetrahydroxystilbene-2-O-β-d-glucoside (TSG) and acetylated-TSG (Ac-TSG) on osteoblast viability, in vivo pharmacokinetics in rats and anti-osteoporotic effects in ovariectomized rat model. Methods: Ac-TSG was obtained by acetylation of TSG, and the purity and structure of Ac-TSG were determined by HPLC and 1H NMR. The effects of TSG and Ac-TSG on MC3T3-E1 cell viability, pharmacokinetics in rats, blood biochemical indexes of OVX model rats were detected. Hematoxylin–eosin (HE) staining was used to observe bone tissue morphology, tartrate-resistant acid phosphatase (TRAP) staining was used to observe osteoclast morphology, micro-CT was used to perform three-dimensional reconstruction of femur, and femur parameters were analyzed. Results: The structure of the compound is Ac-TSG and the purity is more than 98%. Both TSG and Ac-TSG could reduce the damage of oxidative stress to MC3T3-E1 cells and effectively improve the levels of Ca, P, ALP and BGP in serum of OVX rats. Compared with TSG, Ac-TSG has a longer action time in vivo and can improve the femoral structure, the number of trabecular bone and the number of osteoclasts in rats. Conclusion: Ac-TSG conferred protection to MC3T3-E1 cells against oxidative stress-induced damage and enhanced their bioavailability. Simultaneously, Ac-TSG ameliorated abnormal bone metabolism and mitigated bone microstructural changes in OVX rats, exhibiting a protective effect against osteoporosis.
研究领域:
药理学
·
骨科
·
分子生物学
✓ 已验证
DOI
高影响因子
FOOD HYDROCOLLOIDS
·
2025
·
IF 12.4
Akhunzada Bilawal,Muhammad Ishfaq,Shah Zareen,Zhanmei Jiang,Juncai Hou
The demand for innovative and sustainable food structuring technologies has driven significant research into high internal phase Pickering emulsion gels (HIPPEGs) as versatile systems for encapsulation and delivery applications. In this study, we developed high internal phase Pickering emulsion gels (HIPPEGs) stabilized by whey protein isolate microgels (WPIM) complexed with β-cyclodextrin (βCD) for potential applications in 3D food printing. WPIM was prepared through thermal and mechanical treatments, followed by complex formation with βCD at concentrations of 0.5–4.5%. The HIPPEGs, formulated with 75% sunflower oil and 25% aqueous WPIM-βCD dispersions, exhibited enhanced stability and rheological properties. Increasing βCD concentration significantly reduced interfacial tension (from 15.3 to 9.8 mN/m) and contact angle (from 135.3° to 83.2°), indicating improved wettability and interfacial adsorption. Particle size increased (18.2 to 142 μm) with higher βCD and NaCl concentrations, while zeta-potential shifted negatively, enhancing electrostatic repulsion and stability. Rheological analysis demonstrated shear-thinning behavior and increased apparent viscosity (250 to 540 Pa·s) and storage modulus (G') with βCD addition, supporting extrusion and self-supporting characteristics essential for 3D printing. Microscopy revealed uniform droplet encapsulation and a tightly packed structure, minimizing coalescence. Stability tests confirmed structural integrity over 32 days without phase separation. These findings demonstrate that WPIM-βCD-stabilized HIPPEGs possess excellent printability, mechanical strength, and storage stability, offering a scalable approach for designing functional and sustainable 3D-printed food materials.
研究领域:
食品科学
·
材料科学
·
界面化学
✓ 已验证
产品关联
DOI
高影响因子
KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
·
2021
·Vol. 25
·期 2
·131-137
·
IF 2.016
Jing Cheng,Chaoyang Ren,Renli Cheng,Yunning Li,Ping Liu,Wei Wang,Li Liu
Aging is the process spontaneously occurred in living organisms. Cardiac fibrosis is a pathophysiological process of cardiac aging. Mangiferin is a well-known C-glucoside xanthone in mango leaves with lots of beneficial properties. In this study, rat model of cardiac fibrosis was induced by injected with 150 mg/kg/d D-galactose for 8 weeks. The age-related cardiac decline was estimated by detecting the relative weight of heart, the serum levels of cardiac injury indicators and the expression of hypertrophic biomakers. Cardiac oxidative stress and local inflammation were measured by detecting the levels of malondialdehyde, enzymatic antioxidant status and proinflammatory cytokines. Cardiac fibrosis was evaluated by observing collagen deposition via masson and sirius red staining, as well as by examining the expression of extracellular matrix proteins via Western blot analysis. The cardiac activity of profibrotic TGF-β1/p38/MK2 signaling pathway was assessed by measuring the expression of TGF-β1 and the phosphorylation levels of p38 and MK2. It was observed that mangiferin ameliorated D-galactose-induced cardiac aging, attenuated cardiac oxidative stress, inflammation and fibrosis, as well as inhibited the activation of TGF-β1/p38/MK2 signaling pathway. These results showed that mangiferin could ameliorate cardiac fibrosis in D-galactose-induced aging rats possibly via inhibiting TGF-β/p38/MK2 signaling pathway.
研究领域:
药理学
·
心脏病学
·
老年学
·
分子生物学
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2015
·
IF 2.999
Chuanying Wang,Xianhua Cheng
β-NaYF 4 :Yb 3+ /Er 3+ microcrystals codoped with Cr 3+ ions were prepared for the first time via a facile hydrothermal method . The influence of doping concentration of Cr 3+ ions on growth and upconversion (UC) luminescence properties of β-NaYF 4 :Yb 3+ /Er 3+ microcrystals were investigated in detail. Scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectra and photoluminescence (PL) spectra were used for characterization. The results demonstrated that the morphology and size of β-NaYF 4 :Yb 3+ /Er 3+ microcrystals were influenced by doping concentration of Cr 3+ ions, the possible mechanism was proposed. The UC intensity of β-NaYF 4 :Yb 3+ /Er 3+ microcrystals was significantly enhanced by doping of Cr 3+ ions. In contrast to β-NaYF 4 :Yb 3+ /Er 3+ microcrystals without doping of Cr 3+ ions, the green and red emission intensities of the microcrystals codoped with 15 mol% Cr 3+ ions were enhanced by 16 and 7 times, respectively. The enhancement of the UC intensities should be ascribed to the distortion of local symmetry around Er 3+ ions, the UC mechanism was discussed. This work will be helpful for improving the UC intensity of other lanthanide-doped UC nano- and micro-crystals.
研究领域:
材料科学
·
无机化学
·
光功能材料
·
纳米医学
·
生物成像
·
分子影像学
·
光学材料
✓ 已验证
DOI
高影响因子
FOOD AND BIOPRODUCTS PROCESSING
·
2019
·
IF 3.324
Liling Wang,Yifeng Zhou,Yanbin Wang,Yuchuan Qin,Bentong Liu,Minge Bai
Dihydromyricetin (DMY) is the main flavonoid present in vine tea and is also known to possess various beneficial health effects. Extractions of DMY from vine tea were investigated by ultrasonic-assisted extraction (UAE) with β-Cyclodextrin (β-CD) and ionic liquid (IL), which were the two green extraction methods attracting more attentions in recent years. Single factor and response surface methodology (RSM) were used in order to optimize the extraction conditions for obtaining maximum amount of DMY in the two approaches. The results of HPLC analysis showed that the addition of β-CD or 1-hexyl-3-methylimidazolium bromide ([HMim] Br) to the water solution had excellent effects on the extraction of DMY. In β-CD-UAE, the optimum conditions were 3.6% β-CD, ultrasonic time 8 min, liquid–solid ratio of 33 (mL/g), and ultrasonic power 360 W. Molecular docking results indicated that the ‘host-guest’ effect between β-CD and the molecule of DMY in water solution, which utilized molecular recognition and interactions through non-covalent bonding and hydrogen bonding is the main driver of the binding. And for IL-UAE, the optimal conditions were 1.25 mol/L [HMim] Br, ultrasonic time 5.5 min, liquid–solid ratio of 45 (mL/g), and ultrasonic power 240 W. Under above suitable conditions, the extraction yield of DMY can reach to about 40%; moreover, β-CD-UAE and IL-UAE can be easily applied for experimental or industrial scale in food or functional food use.
研究领域:
食品科学
·
植物化学
✓ 已验证
DOI
高影响因子
Nutrients
·
2020
·Vol. 12
·期 6
·1889
·
IF 4.546
Nancy Saji,Nidhish Francis,Lachlan J. Schwarz,Christopher L. Blanchard,Abishek B. Santhakumar
Oxidative stress is known to modulate insulin secretion and initiate gene alterations resulting in impairment of β-cell function and type 2 diabetes mellitus (T2DM). Rice bran (RB) phenolic extracts contain bioactive properties that may target metabolic pathways associated with the pathogenesis of T2DM. This study aimed to examine the effect of stabilized RB phenolic extracts on the expression of genes associated with β-cell function such as glucose transporter 2 (Glut2), pancreatic and duodenal homeobox 1 (Pdx1), sirtuin 1 (Sirt1), mitochondrial transcription factor A (Tfam), and insulin 1 (Ins1) in addition to evaluating its impact on glucose-stimulated insulin secretion. It was observed that treatment with different concentrations of RB phenolic extracts (25-250 µg/mL) significantly increased the expression ofGlut2,Pdx1,Sirt1, Tfam,andIns1genes and glucose-stimulated insulin secretion under both normal and high glucose conditions. RB phenolic extracts favourably modulated the expression of genes involved in β-cell dysfunction and insulin secretion via several mechanisms such as synergistic action of polyphenols targeting signalling molecules, decreasing free radical damage by its antioxidant activity, and stimulation of effectors or survival factors of insulin secretion.Keywords:rice bran;phenolic extracts;β-cell function;gene expression;insulin secretion
研究领域:
营养学
·
分子生物学
·
内分泌学
·
药理学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）