Acupuncture and Herbal Medicine
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2024
·Vol. 4
·期 4
·487
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IF 0
Wang Zhiyun,Shang Haihua,Gou Wenfeng,Xu Feifei,Hou Yue,Liu Gaiting,Ren Zhonghao,Li Yiliang,Tian Yuhua,Li Wei,Wang Yuefei,Hou Wenbin
Objective: Camellia nitidissima Chi, a Chinese medicine commonly used by ethnic minorities in Guangxi, China, is beneficial for clearing heat, detoxifying, inducing diuresis, and suppressing swelling. It has various pharmacological properties, including antitumor, anti-inflammatory, and antioxidant. However, its potential application in radioprotection remains unclear. In this study, we aimed to determine whether Camellia nitidissima Chi has radioprotective effects against radiation-induced gastrointestinal and hematopoietic damage. Methods: The 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical and 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) techniques were used to assess the ability of Camellia nitidissima Chi to scavenge free radicals. We conducted a 30-day survival rate experiment to evaluate the radioprotective capabilities of Camellia nitidissima Chi. Additionally, we developed models of radiation-induced intestinal and hematopoietic damage. Alterations in the white blood cell (WBC) count, total superoxide dismutase (T-SOD), glutathione (GSH), and protein expression linked to apoptosis were observed. Results: Camellia nitidissima Chi scavenged 84.72% and 93.47% of DPPH and ABTS, had a certain radiation protection potential, and increased the survival rate of mice to over 90%. Moreover, following exposure, Camellia nitidissima Chi enhanced WBC, T-SOD, and GSH levels. Camellia nitidissima Chi increased B-cell lymphoma-extra large (BCL-XL) expression and suppressed Bcl-2 associated X protein (BAX) expression, providing radioprotection to cells. Conclusions: Camellia nitidissima Chi has a strong antioxidant ability; it can improve the survival rate of mice after lethal dose irradiation and protect against radiation-induced hematopoietic and gastrointestinal damage. These findings can serve as a guide for using Chinese medicines for radioprotection.
研究领域:
药理学
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放射医学
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民族医药
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生物学
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DOI
CHEMICAL ENGINEERING JOURNAL
·
2015
·
IF 4.321
Yi-Si Feng,Cui Liu,Yu-Mei Kang,Xue-Mei Zhou,Liang-Liang Liu,Jin Deng,Hua-Jian Xu,Yao Fu
Biomass glycerol is an important raw material for many available chemicals, such as 1,2-propanediol (1,2-PDO). Hydrogenolysis of glycerol to 1,2-PDO is considered as a sustainable process with renewable potential application. In this paper, a series of bimetallic PdCu-KF/γ-Al 2 O 3 were prepared and the structures of catalysts were characterized by XRD, XPS, TEM and CO 2 -TPD. By measuring the activity of the catalyst, we found that PdCu-KF/γ-Al 2 O 3 (Pd:Cu:KF = 0.05:1:0.5) can be used as an efficient catalyst for hydrogenolysis of glycerol to 1,2-PDO, with 98.3% selectivity and nearly 100% conversion (200 °C, 2.5 MPa initial H 2 pressure, 20 h).
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DOI
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OZONE-SCIENCE & ENGINEERING
·
2023
·
IF 2.7
Tingfeng Xue,Jing Zhang,Jingcheng Wei,Bingyan Zhu,Jianwei Song,Shuang Xu,Liwei Pan
In this study, a novel NiAl2O4/NiO@γ-Al2O3 catalyst was prepared by the impregnation-calcination method and used for the catalytic ozonation of tartrazine wastewater. The NiAl2O4/NiO@γ-Al2O3 catalyst were characterized by X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscopy, transmission electron microscopy, and nitrogen adsorption-desorption experiments. It was found that NiAl2O4/NiO@γ-Al2O3 significantly improved the removal of chemical oxygen demand of the dye wastewater from 40% for the direct ozone oxidation to 65%, and the ozone concentration depletion for catalytic ozonation was 120% of that for ozone alone. The catalytic activity of the catalyst did not significantly decrease after reuse for six cycles and leaching concentration of metal ions less than 1%. However, the toxicity of the dye wastewater was greatly reduced after the catalytic ozonation. The pyridine Fourier transform infrared spectroscopy showed the catalytic ozonation reaction was related with Lewis acid sites. The presence of hydroxyl radicals, superoxide anion radicals, and singlet oxygen was verified by an electron paramagnetic resonance, and the quenching experiments confirmed that the removal of organic pollutants from the tartrazine wastewater mainly relied on hydroxyl radicals and singlet oxygen. Therefore, the NiAl2O4/NiO@γ-Al2O3 could be an effective catalyst for the rapid catalytic ozonation of dye wastewater.
研究领域:
环境工程
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催化化学
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水处理
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高级氧化技术
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材料科学
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DOI
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ACS Applied Materials & Interfaces
·
2026
·
IF 7.8
Ye Xuanzhen,Fang Bin,Liu Xin,Liu Shilin,Wang Fangbao,Song Xiaoyuan,Wu Bin,Xu Wei,Huang Wei,Xu Zhichun,Geng Jiahao,Zhao Dou,Chen Liang,Xu Yadong
The zero-dimensional (0D) copper halide perovskite Cs 3 Cu 2 I 5 exhibits outstanding luminescence and scintillation properties, making it a highly promising scintillator for γ-ray detection. Solution growth is a favorable and inexpensive method for growing Cs 3 Cu 2 I 5 single crystals; however, scalable growth of Cs 3 Cu 2 I 5 crystals with low defect density suffers from the unavoidable formation of secondary phase CsCu 2 I 3 . In this work, centimeter-size, high quality Cs 3 Cu 2 I 5 single crystals are synthesized via a constant-temperature solvent evaporation crystallization (CT-SEC) method, in which the formation of CsCu 2 I 3 can be eliminated by precursor engineering. The phase evolution behavior is elucidated as the decrease in the I − /Cu + concentration ratio during the growth of the Cs 3 Cu 2 I 5 crystal. Through synergistic regulation of precursor antioxidative treatment and raw material stoichiometry, the long-term phase-stable growth of Cs 3 Cu 2 I 5 single crystals is achieved. The obtained Cs 3 Cu 2 I 5 crystals exhibit excellent energy resolutions of 5.38% for 137 Cs and 13.30% for 241 Am γ-ray irradiation.
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PubMed
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CHEMICAL ENGINEERING SCIENCE
·
2023
·
IF 4.7
Fuming Miao,Shuai Zhang,Xueliang Sun,Yamin Li,Ruize Shang,Wenli Wu,Weizhou Jiao,Youzhi Liu
In this study, Mn-CoO X / γ -Al 2 O 3 (MCA) was prepared by impregnation for catalytic ozonation of phenol in a rotating packed bed (RPB), and the effects of high gravity factor ( β ), liquid flow rate ( Q L ), initial solution pH and gaseous ozone concentration ( C O 3 ) on the mineralization of phenol were explored. The results show that the degradation rate of phenol ( η phenol ) reaches 100% at 9 min and the mineralization rate ( η TOC ) reaches 95.01% at 45 min under conditions of β = 104, C O 3 = 80 mg L -1 , Q L = 80 L/h, and pH = 6. Compared with the bubbling reactor (BR)/MCA/O 3 and O 3 /RPB systems, the η TOC of the MCA/O 3 /RPB system is increased by 25.81% and 40.85%, respectively. The electron paramagnetic resonance (EPR) results reveal that hydroxyl radical (·OH) plays a critical role in the degradation of phenol by MCA catalyzed ozonation. The quenching experiment using tertiary butyl alcohol (TBA) as a scavenger of ·OH reveals that the ratio of direct and indirect degradation of phenol is 16:9. The intermediates generated during the degradation of phenol were detected by gas chromatography-mass spectrometry (GC–MS), and possible degradation pathways were proposed. In conclusion, MCA-catalyzed ozonation and RPB have a synergistic effect on ·OH initiation and improve the degradation and mineralization of phenol. This study provides a new perspective for the degradation of phenol.
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CHEMISTRY-A EUROPEAN JOURNAL
·
2023
·Vol. 29
·期 52
·e202300950
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IF 4.3
Fukun Li,Ronghe Yang,Zheng Tian,Ziting Du,Jinhang Dai,Xingmin Wang,Ning Li,Jie Zhang
Graphical Microwave-assisted one pot cascade transformation of furfural to γ-valerolactone catalyzed by Sc(OTf) 3 . γ-Valerolactone (GVL) is considered as a star biochemical which can be used as a green solvent, fuel additive and versatile organic intermediate. In this study, metal triflate (M(OTf) n ) was utilized as the catalyst for one-pot transformation of furfural (FF) to GVL in alcohol media under microwave irradiation. Alcohol plays multiple functions including solvent, hydrogen donor and alcoholysis reagent in this cascade reaction process. And process efficiency of GVL production from FF upgrading is strongly related to the effective charge density of selected catalyst and the reduction potential of selected alcohol. Complex (OTf) n -M−O(H)R, presenting both Brønsted acid and Lewis acid, is the real catalytic active species in this cascade reaction process. Among various catalysts, Sc(OTf) 3 exhibited the best catalytic activity for GVL production. Various reaction parameters including the Sc(OTf) 3 amount, reaction temperature and time were optimized by the response surface methodology with the central composite design (RSM-CCD). Up to 81.2 % GVL yield and 100 % FF conversion were achieved at 143.9 °C after 8.1 h in the presence of 0.16 mmol catalyst. This catalyst exhibits high reusability and can be regenerated by oxidative degradation of humins. In addition, a plausible cascade reaction network was proposed based on the distribution of product.
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PubMed
高影响因子
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
·
2023
·Vol. 112
·期 1
·e35316
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IF 3.4
Qinwei Yang,Jiadong Zhu,Jing Chen,Peizhi Zhu,Chunxia Gao
As potential alternatives for calcium phosphate bone cements, magnesium phosphate bone cements (MPC) have attracted considerable attention in recent years. However, their several defects, such as rapid setting times, highly hydration temperature and alkaline pH due to the part of the unreacted phosphate, restricted their applications in human body. With aim to overcome these defects, a novel polypeptite poly(γ-glutamic acid) (γ-PGA) modified MPC were developed. Effect of γ-PGA content on the injectability, anti-washout ability, setting times, hydration temperature, mechanical compressive strength, in vitro bioactivity and degradation were investigated. Moreover, in vitro cyto-compatibility was evaluated using MC3T3-E1 cells by CCK-8 and Live/Dead staining. All these results indicated that the 10%PGA-MPC with an improved handling performances, low hydration temperature, high mechanical compressive strength, and good cyto-compatibility hold a great potential for bone repair and regeneration.
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高影响因子
Journal of Materials Chemistry B
·
2023
·
IF 7
Chuang Hu,Haoran Ji,Yan Gong,Xuhui Yang,Yunxuan Jia,Yuanhao Liu,Guangyu Ji,Xiansong Wang,Mingsong Wang
Following the global COVID-19 pandemic, the incidence of tracheal epithelial injury is increasing. However, the repair of tracheal epithelial injury remains a challenge due to the slow renewal rate of tracheal epithelial cells (TECs). In traditional nebulized inhalation treatments, drugs are enriched in the lungs or absorbed into the blood, reducing drug concentration at the tracheal injury site. In this study, we prepared an epidermal growth factor (EGF)-loaded gamma-polyglutamic acid (γ-PGA)/epsilon-poly-L-lysine (ε-PLL) (PP) hydrogel (EGF@PP) to promote the repair of tracheal epithelial injury. Epidermal growth factor promotes the proliferation of TECs and enhances vascularization, thereby accelerating injury repair. The PP hydrogel exhibits outstanding wet adhesion, slow drug release, and antibacterial and anti-inflammatory properties, making it suitable for application in the airways and creating an environment conducive to epithelial repair. Here, we established a rabbit model of tracheal injury using a laser to destroy the tracheal epithelium and delivered EGF@PP powder to the injury site under fiberoptic bronchoscopy guidance. Our findings revealed that this was an effective therapeutic strategy for accelerating the repair of tracheal epithelial injury.
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DOI
PubMed
高影响因子
JOURNAL OF MAGNETIC RESONANCE IMAGING
·
2023
·
IF 4.4
Xue Yang,Ying Liu,Cai-xia Fu,Ying-Hua Chu,Qun Chen,He Wang,Da-Xiu Wei,Ye-Feng Yao
Background Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter in human brains, playing a role in the pathogenesis of various psychiatric disorders. Current methods have some non-neglectable shortcomings and noninvasive and accurate detection of GABA in human brains is long-term challenge. Purpose To develop a pulse sequence capable of selectively detecting and quantifying the 1 H signal of GABA in human brains based on optimal controlled spin singlet order. Study Type Prospective. Subjects/Phantom A phantom of GABA (pH = 7.3 ± 0.1) and 11 healthy subjects (5 females and 6 males, body mass index: 21 ± 3 kg/m 2 , age: 25 ± 4 years). Field Strength/Sequence 7 Tesla, 3 Tesla, GABA-targeted magnetic resonance spectroscopy (GABA-MRS-7 T, GABA-MRS-3 T), magnetization prepared two rapid acquisition gradient echoes sequence. Assessment By using the developed pulse sequences applied on the phantom and healthy subjects, the signals of GABA were successfully selectively probed. Quantification of the signals yields the concentration of GABA in the dorsal anterior cingulate cortex (dACC) in human brains. Statistical Tests Frequency. Results The 1 H signals of GABA in the phantom and in the human brains of healthy subjects were successfully detected. The concentration of GABA in the dACC of human brains was 3.3 ± 1.5 mM. Data Conclusion The developed pulse sequences can be used to selectively probe the 1 H MR signals of GABA in human brains in vivo. Evidence Level 1 Technical Efficacy Stage 1
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Journal of Cleaner Production
·
2022
·
IF 11.072
Xiyan Xu,Shuming Liu,Peifu Sun,Zhiren Guo,Kate Smith,Dongxiang Zhang,Hansheng Li,Jorge Bedia,Carolina Belver
Reverse osmosis (RO) does not effectively remove carcinogenic 1,4-dioxane and, consequently, this compound needs to be eliminated from RO-reclaimed water for potable reuse. This work analyzed the 1,4-dioxane mineralization on a solar-driven system using home-made catalysts with iron tungstate (wt%: 1–20%) supported on nano-γ-alumina. Characterization has been conducted using SEM-EDS, N 2 adsorption-desorption, XRD , XPS , UV–vis spectra, PL , EIS and transient photocurrent analyses. The BET area of FeW/nAl5 catalyst was close to 200 m 2 g −1 . XRD and XPS analysis confirmed that iron tungstate was loaded on the support. Mineralization has been checked with catalyst concentration ranging 0.1–0.9 g L −1 . More than 90% TOC removal was achieved, with no iron or tungsten leaching after 4 h reaction. Scavenging tests, ESR, ionic chromatography and UPLC-MS analysis confirms that • OH and O 2 •− radicals were responsible for 1,4-dioxane degradation. Iron promotes • OH formation and 1,4-dioxane photodegradation . Several ring-opening intermediates were identified, whereas condensation byproducts were detected in minor amounts. Based on byproduct identification, reaction pathway was postulated.
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FUEL
·
2022
·
IF 8.035
Tianliang Lu,Xianfeng You,Yanlong Zong,Yongming Xu,Xiaomei Yang,Lipeng Zhou
Production of γ-valerolactone (GVL) from ethyl levulinate (EL) was studied by catalytic transfer hydrogenation (CTH) strategy under mild conditions. Hydrothermally synthesized Sn-Beta zeolites with high crystallinity show high catalytic activity and selectivity. With isopropanol as hydrogen source, 97.1 % GVL yield with 100 % selectivity was given under 110 °C. Crystallization time for synthesis of Sn-Beta showed great effect on the catalytic performance. Sn-Beta- x d catalysts with longer crystallization time (≥7 days) have high crystallinity and better catalytic performance. Firstly, longer crystallization time is necessary for the formation of large amount of Lewis acid sites which catalyze the conversion of EL to GVL. Secondly, high level of silanol groups in Sn-Beta has negative effect on the catalytic performance. High crystallinity means the amount of silanol groups in Sn-Beta- x d at a low level which is favorable for this CTH reaction. Meanwhile, this is why hydrothermally synthesized Sn-Beta shows higher catalytic activity than post-synthesized Sn-Beta in the conversion of EL to GVL. Furthermore, the catalyst was reusable.
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JOURNAL OF ANALYTICAL AND APPLIED PYROLYSIS
·
2022
·
IF 6.437
Koïta Djakaria,Ziyue Tang,Jingai Shao,Xu Chen,Haoyu Xiao,Joseph Smith,Haiping Yang,Hanping Chen
Furfural is one of the top valuable building block chemicals, the selective production of furfural from biomass has attracted increasing concerns in recent years. In this work, a novel method for the selective production of furfural through cellulose catalytic pyrolysis with WO 3 /γ-Al 2 O 3 was reported, and the synergistic effect between γ-Al 2 O 3 and WO 3 was explored. Compared with cellulose pyrolysis alone, the addition of γ-Al 2 O 3 improved the selectivity of furans and greatly inhibited the formation of sugars; while, WO 3 addition promoted the formation of levoglucosenone . When (20–40%) WO 3 /γ-Al 2 O 3 were added, the amount of sugars was further reduced, and the yields of furans (furfural and 2-methylfuran, in particular) were further increased at the same time. Under the optimum conditions (temperature = 600 °C, residence time = 15 s, and catalyst to cellulose mass ratio of 4), 30%WO 3 /γ-Al 2 O 3 showed the best performance, and the selectivity and yield of furfural were improved by nearly 100% and 300%, respectively, as compared with cellulose pyrolysis alone. In addition, compared with γ-Al 2 O 3 , the addition of 30%WO 3 /γ-Al 2 O 3 further increased the yield of furfural and 2-methylfuran to about 50% and 200%, respectively. The high selectivity and yields of furans with WO 3 /γ-Al 2 O 3 addition might be due to that WO 3 crystals in the composite promote the formation of levoglucosenone, which is further converted to additional furans through the Lewis acid sites of γ-Al 2 O 3 . The study may provide some meaningful advices for improving the production of furfural from green catalytic pyrolysis of cellulose.
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