LANGMUIR
·
2025
·
IF 3.9
Yu Si,Junwang Liu,Yingyi Ma,Xinran Li,Xinzheng Li,Zhihao Zhu,Kexin Liu,Shiyun Wang
Electrochemical sensors capable of detecting different types of biomolecules using a single electrode are highly desirable for simplifying analytical platforms and expanding their practical applicability. Herein, we develop a multifunctional electrochemical sensor based on a 3D honeycomb-like porous rGO/PPy-POM composite film for the independent detection of dopamine (DA) and folic acid (FA), two chemically distinct and clinically relevant biomolecules. The electrode is fabricated through a facile, low-cost, and environmentally friendly breath figure method to create a 3D porous reduced graphene oxide (rGO) framework, followed by codeposition of polypyrrole (PPy) and polyoxometalates (POMs). The synergistic effect of the hierarchical porous structure and the electroactive components significantly enhances the sensor’s surface area, charge transfer efficiency, and electrochemical response. The as-prepared porous rGO/PPy-POM electrode exhibits excellent sensing performance toward DA and FA. It achieves a wide linear range of 0–2300 μM and a low detection limit of 72 nM within 0–10 μM for DA detection, while offers a linear range of 0–3500 μM and a detection limit of 82 nM in the low concentration range for FA detection. The sensor also shows excellent selectivity against common interferents, outstanding repeatability and reproducibility, and long-term operational stability. Importantly, in real human urine samples, the sensor yields recovery rates between 96.2 and 109.8%, confirming its reliability and accuracy for practical biological analysis. This work offers a robust strategy for constructing multifunctional electrochemical sensors capable of detecting diverse biomolecular targets using a unified sensing platform.
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2025
·
IF 21.1
Jiaojiao Sun,Mengxia Shen,A.jun Chang,Jianfeng Huang,Pengbo Wang,Yonghao Ni
Conventional metal-nitrogen-carbon single-atom catalysts (M-N-C SACs) are plagued by electron localization effects arising from symmetric coordination geometries and the absence of synergistic interactions among isolated active sites, both of which critically undermine oxygen reduction reaction (ORR) catalytic performance. To address these limitations, this study introduces a multiscale synergistic engineering strategy that integrates asymmetric coordination design with bioinspired structural innovation. Specifically, the symmetry of the Fe-N 4 coordination is disrupted to generate Fe-N 3 Se sites, which facilitate charge density redistribution; while Fe atomic clusters (FeACs) are strategically integrated to construct asymmetric catalytic centers that activate O 2 and promote O-O bond cleavage. A hierarchical porous carbon submicronspheres architecture, inspired by alveolar structures and featuring gradient-distributed micropores and mesopores, has been developed to enhance the mass transport efficiency at triple-phase interface. Overall, we have developed FeSAs and FeACs anchored on alveolar-inspired hierarchically porous nitrogen/selenium co-doped carbon submicronspheres (Fe SA+AC -N/Se-AHCs), which exhibits outstanding ORR activity (E o =0.99 V, E 1/2 =0.90 V) and long-term durability. Theoretical analyses further demonstrate that the electronic coupling between Fe-N 3 Se sites and FeAC synergistically optimizes the adsorption free energies of critical *OOH and *O intermediates, thereby accelerating O-O bond dissociation. This work presents a comprehensive cathode catalyst platform for developing high-energy-density and long-cycle-life Zinc-air batteries.
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高影响因子
ANALYTICA CHIMICA ACTA
·
2025
·
IF 6
Zhou Yang,Lingling Dai,Fangfei Liu,Kun Jia,Zhiyuan Ren,Yanmei Yang,Qingmeng Zhang,Weifeng Li,Ming Chen
Background Folate is an essential nutrient, but its bioavailability varies greatly depending on the molecular form present in food. The intake of forms that are not readily absorbed by the human body may lead to insufficient folate levels, particularly during pregnancy, thereby increasing the risk of birth defects. As a result, it is essential to develop a highly sensitive and accurate method capable of distinguishing between the two most common natural folates, 5-methyltetrahydrofolate (5-MTHF) and 5-formyltetrahydrofolate (5-FTHF), to ensure proper folate intake and health outcomes. Results In this study, a photochemical method was employed to load gold nanoparticles (Au NPs) onto carbon nanotubes (CNTs), successfully synthesizing CNTs@Au NPs nanocomposites that exhibit excellent thermal stability and robust surface-enhanced Raman scattering (SERS) activity. These nanocomposites, capable of maintaining structural integrity at temperatures as high as 400 °C, serve as highly effective substrates for in situ high-temperature SERS detection. Using this reliable high-temperature-assisted SERS approach, the structural changes of both folates at elevated temperatures were effectively monitored, enabling clear molecular fingerprinting and distinct differentiation between the two natural folates. Moreover, the CNTs@Au NPs demonstrate exceptional sensitivity, achieving a detection limit as low as 10 -8 M for both 5-MTHF and 5-FTHF, enabling accurate quantification of mixed folate samples and demonstrating reliable performance in real sample analysis. Significance The CNTs@Au NPs with in situ high-temperature SERS capabilities show great potential for various analytical applications. In particular, they provide an effective method for monitoring the quality of folate in dietary supplements and fortified foods, thus contributing significantly to the safety and quality assurance of folate products in the market.
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高影响因子
Foods
·
2025
·Vol. 14
·期 18
·3145
·
IF 5.1
Jing Li,Luyao Wang,Jijie Shi,Xuelian Wu,Jing Zhang,Yuecheng Xu,Xinhui Wang,Xiaoqin Li
Here, a highly sensitive and selective electrochemical sensor for dopamine (DA) determination in pork was developed. This sensor was fabricated using iron-based nanocomposites (Fe@(C-S-N)) to modify a glassy carbon electrode (GCE) substrate. The Fe@(C-S-N) nanocomposites were synthesized through a facile low-temperature chemical precipitation approach by adopting ferrous sulfate and melamine as raw materials, with their structural and compositional properties thoroughly investigated using multiple analytical techniques, including X-ray diffraction (XRD), electron microscopy (EM), X-ray photoelectron spectroscopy (XPS), and energy-dispersive spectra (EDS). Cyclic voltammetry (CV), chronocoulometry (CC), and differential pulse voltammetry (DPV) were adopted to investigate the electrochemical performance of the fabricated Fe@(C-S-N)/GCE sensor. Notably, the sensor demonstrated a linear response range from 0.05 to 100 μM with a minimal limit of detection (LOD) of 46 nM. Lastly, the fabrication sensor was used to determine DA in pork samples, showing an acceptable recovery of over 96.89%. Thus, the proposed sensor could offer an effective method for determining DA in pork.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Samuel Ariyo Okaiyeto,Shi-Han Yu,Haiou Wang,Jin-Hong Zhao,Cun-Shan Zhou,Ahmed Jamilu Mustapha,An-An Zhang,Fan Yang,Jing-Shou Zhang,Hong-Wei Xiao
This study evaluates vacuum-steam pulsed blanching (VSPB) as a pretreatment for Vigna unguiculata pods, focusing on drying kinetics, nutritional quality, and anti-nutritional factors. Pods underwent 0–4 VSPB cycles, followed by hot air drying at 50, 60, and 70 °C. VSPB reduced peroxidase activity to 4.8 %, enhancing enzyme inactivation. Texture analysis revealed an 85.6 % reduction in hardness, while the Midilli model provided the best description of drying kinetics (R 2 ≥ 0.9979). Specific energy consumption decreased by up to 40 % at 70 °C for blanched samples. VSPB preserved ascorbic acid, vitamin A, and chlorophyll, reduced lignin by 29.63 %, and lowered lectins from 71.01 to 8.88 Hu/mg. Folate retention declined with increased cycles. SEM and TEM analyses revealed microstructural and ultrastructural disruptions enhancing moisture diffusivity. VSPB proves effective in reducing anti-nutritional factors and retaining nutrients, offering a promising pretreatment for Vigna unguiculata with potential industrial applications.
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高影响因子
JOURNAL OF LUMINESCENCE
·
2025
·
IF 3.6
Yanni Jie,Zengbo Fan,Jiang Yan,Fuchun Li,Ting Meng,Zhenli Guo,Penggao Dai
Carbon dots (CDs) with room-temperature phosphorescence (RTP) characteristics have drawn considerable attention because of their broad applications in various area. However, achieving water-soluble RTP CDs remains highly challenging owing to the severe phosphorescence quenching effect caused by dissolved oxygen in aqueous solutions. Herein, a realizable strategy of attaining long-lifetime and high stability RTP CDs-based composites in aqueous solutions is proposed via constructing a rigid hydrogen-bonded network. The synthesized composites display an ultra-long phosphorescence lifetime of 1.38 s in solid state and 316 ms in aqueous phase. Moreover, the RTP emission remains visible to naked eye for up to 10 s even under strongly acidic or alkaline conditions. TEM, XRD, FT-IR, and XPS analyses confirmed the successful conjugation of cyanuric acid (CA) with carbon dots (CDs) which the rigid CA framework effectively restricted the chromophore vibrations and rotations, minimizing non-radiative recombination of triplet excitons. Finally, applications of CDs in screen printing, anti-counterfeiting and information protection were explored.
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