Solar RRL
·
2024
·
IF 6
Meijuan Ding,Mei Li,Jingzhi Wang,Zhiliang Jin
Herein, the application of graphdiyne (GDY) in photocatalytic splitting of water and hydrogen evolution is explored. In this article, GDY is prepared by ball milling using calcium carbide as raw material, and it is compounded with phosphating Mo–metal-organic frameworks (MOFs), to explore the photocatalytic hydrogen evolution performance and hydrogen evolution mechanism of composite catalysts. In the results, it is shown that the P–Mo–MOFs (PMF)/G-25 composite photocatalyst has the best hydrogen evolution activity, and the hydrogen evolution rate is highest at pH = 9, reaching 1668.5 μmol g −1 h −1 . Through the four-cycle hydrogen evolution cycle stability test, the PMF/G-25 composites still has good hydrogen evolution stability. It is shown that the combination of phosphating Mo–MOFs and GDY can enhance the hydrogen evolution activity and has excellent hydrogen evolution performance. In the Mott–Schottky test, it is found that PMF and GDY are n-type semiconductors. The conduction and valence values are −0.56 and 1.10 eV for GDY, and −0.68 and 0.97 eV for PMF, respectively. The mechanism of photocatalytic hydrogen evolution is analyzed, and it is speculated that S-Scheme heterojunction is formed between PMF and GDY to further promote photocatalytic hydrogen evolution.
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NEW JOURNAL OF CHEMISTRY
·
2025
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IF 2.5
Ming Huang,Yingfeng Wang,Yuhan Zhu,Maoli Yin,Zhipeng Ma,Xiaojuan Li
To address the challenge of antibiotic resistance and cross-infection from microorganisms, chitosan (CS) was covalently bound with rose bengal (RB) and blended with polyethylene oxide (PEO) to prepare nanofiber membranes with good antibacterial properties. Morphological and structural characteristics confirmed successful integration of RB-modified CS (CS-RB) without compromising the fiber morphology or stability of PEO/CS-RB nanofiber membranes. FT-IR and TG analyses were employed to characterize the chemical structure and thermal stability of PEO-based membranes. With visible light irradiation, PEO/CS-RB nanofiber membranes efficiently generated reactive oxygen species (ROS), enabling rapid inactivation of all Escherichia coli (E. coli), Staphylococcus aureus (S. aureus) and Candida albicans (C. albicans) within 30 min. The PEO-based membranes exhibited well-balanced hydrophilicity and water stability, along with low hemolytic activity, indicating good biocompatibility. This strategy creates PEO-based membrane materials that exhibit good biocompatibility, hydrophilicity, and photodynamic antibacterial properties, making them suitable for use in the biomedical and healthcare fields.
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ACS Nano
·
2025
·
IF 16
Chang Liu,Yuxi Gao,Yibo Qi,Zhenyi Zhu,Liping Liu,Kuncheng Lv,Xiaoye Lin,Yang Yu,Xinghui Si,Wantong Song,Wei Li
Exploiting localized, sustained-release drug delivery carriers to enhance the efficiency of tumor immunotherapy has become a major research interest. However, due to the multistep nature of immune activation and the need to target multiple sites─such as simultaneously activating both tumors and lymph nodes─using a single delivery carrier to meet all the complex requirements of immune activation poses significant challenges and limitations. Here, we report a self-adjuvant gel (SAG) for the delivery of the chemotherapeutic agent doxorubicin (DOX) and the immune adjuvant TLR-9 agonist CpG to tumor sites and lymph nodes, enabling sequential, multistep immune activation. This SAG is cross-linked by polyethylenimine grafted with 4-benzimidazole (PEI-4BImi), which has innate immune activation properties, with oxidized dextran. The released PEI-4BImi further assembles in situ with tumor antigens to form nanoparticles of appropriate sizes that can drain to the lymph nodes, promoting antigen presentation and dendritic cell (DC) activation. The SAG exhibits sustained degradation and drug release both in vitro and in vivo over 25 days, efficiently transporting CpG and antigens to the lymph nodes and enhancing DC activation within the lymph nodes. In vivo therapeutic results demonstrated that the SAG could suppress tumor growth, achieving 93% tumor inhibition rates in a subcutaneous liver tumor model and 97% in an orthotopic colon tumor model. Importantly, the immune activation mechanisms, including antigen release and presentation, DC activation, and T-cell priming, were further confirmed through flow cytometry, RNA-seq, and proteomics. Collectively, this SAG presents a potent targeted strategy for cancer immunotherapy.
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高影响因子
RSC Advances
·
2025
·Vol. 15
·期 51
·43676-43682
·
IF 4.6
Hua Zeng,Xiaoyi Sun,Qian Li,Sheng Song
Thermotropic liquid crystalline polymers (TLCPs) have been widely studied since the 1970s, and producing TLCPs in a more efficient way for both cost saving and performance enhancement has always intrigued us. One of the most effective ways is further increasing the degree of acetylation of monomers. Herein, we report a strategy of introducing a second acetylating agent, acetylates of polyphenols, which works at high temperatures when the first acetylating agent, acetic anhydride, is removed from the system. A model reaction proved that benzene-1,3,5-triyl triacetate (PGAc) could efficiently acetylate phenol to form phenyl acetate at 200 °C in a short time (1 h), which was evidenced by 1H NMR. Adding the second acetylating agent, PGAc, in the polycondensation of HBA and HNA without modifying the process flow accelerated the propagation stage even in the absence of catalyst as shown by the data of distillate with time and the evacuation time of the melt polycondensation. Furthermore, other acetylates of polyphenols were also found to be acetylating agents to accelerate the polymerization and form a series of new TLCPs, inserting a small amount of which didn’t affect the chemical structures and thermodynamic properties much. The strategy of introducing a second acetylating agent shows great potential in both theoretical research and practical application.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Xin Wang,Shuangjie Qin,Caiwen Wu,Hongbo Li,Hongjuan Li,Jinghua Yu
Milk fat globule membrane materials possess diverse biological activities and excellent emulsifying properties, but their application in the dairy industry remains limited. In this study, high-fat emulsions were prepared by replacing anhydrous milk fat with high-fat cream at different ratios, and their physicochemical properties were characterized. The interfacial composition, microstructure, and mechanical properties were analyzed using sodium dodecyl sulfate polyacrylamide gel electrophoresis, nuclear magnetic resonance, laser confocal microscopy, and atomic force microscopy. The results revealed that samples with added membrane materials exhibited superior stability during storage and under simulated gastrointestinal conditions. Membrane proteins and phospholipids adsorbed heterogeneously on the milk fat globule (MFG) interface and exhibited stronger fluorescence. The addition of membrane materials reduced the Young's modulus of the interfacial membrane (646.17 ± 5.24 kPa). The emulsion prepared via this method was enriched with membrane components, altering interfacial molecular distribution and mechanical properties, enhancing MFG stability.
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Materials Today Energy
·
2025
·
IF 8.6
Hongliang Fu,Qiaowei Wang,Yue Lian,Yongfeng Hu,Jing Zhao,Huaihao Zhang
It is crucial to rationally design catalysts with high activity and strong stability for electrolytic water oxygen evolution reaction (OER). Here, Ni-FeNbO 4 @NC microspheres were successfully synthesized as OER catalysts by interface optimization and Ni-doping. To address FeNbO 4 problems such as easy agglomeration, low catalytic activity and poor electrical conductivity, the catalyst was incorporated in N p-orbital of imidazole and metals (Ni and Fe) empty d-orbitals to form coordination compound, thus avoiding oxides direct contact and effectively improving dispersion. Moreover, Ni-doping provides additional catalytic active sites, good current impact resistance and large intrinsic conductivity for Ni-FeNbO 4 @NC. Besides, under high-temperature carbonization, the Ni-FeNbO 4 surface imidazole evolves into N-containing carbon layer, which enhances overall electrical conductivity to reduces ohmic overpotential. According to density functional theory calculations (DFT), Ni-doping lowers Gibbs free energy of OER decisive rate step, and enlarges reaction kinetics. From in-situ Fourier Transform infrared spectroscopy (FTIR) and in-situ differential electrochemical mass spectrometry (DEMS), Ni-FeNbO 4 @NC displays multiple types of catalytic active sites (Ni∗, and C-N∗) and efficient oxygen production efficiency. Under the synergistic effect of interface optimization and Ni-doping, Ni-FeNbO 4 @NC exhibits good catalytic activity in OER (low overpotential: 286 mV@10 mA cm −2 , small Tafel slope: 56.7 mV dec −1 , 50 h long stability).
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LANGMUIR
·
2025
·
IF 3.9
Ruiyv Bai,Weian Huang,Zengbao Wang,Yunfeng Liu,Lin Jiang
A novel Mannich base quaternary ammonium salt (MIB) was synthesized via a two-step method using imidazole, acrylamide, and benzyl bromide as primary raw materials. Its corrosion inhibition performance for N80 carbon steel in 20% HCl solution was investigated through weight loss and electrochemical experiments, and the synergistic effects between MIB and different additives were evaluated. MIB demonstrated potential as a temperature-resistant inhibitor, exhibiting a corrosion rate of 6.04 g·m–2 ·h–1 and an inhibition efficiency (IE) of 99.3% at 363 K with the addition of 1% MIB. A notable synergistic effect was observed when MIB was used in conjunction with KI. Under more severe conditions (433 K, 3 MPa, 20% HCl), the system maintained a corrosion rate of 59.12 g·m–2·h–1 while still achieving a high IE of 95%. Adsorption kinetics and thermodynamics studies revealed that the adsorption of MIB on the N80 steel surface followed the Langmuir adsorption model, increasing the energy barrier of the corrosion reaction and thereby making the process more difficult to occur. Theoretical calculations and surface analysis indicated that both neutral and protonated forms of MIB possess electron-donating and electron-accepting capabilities, which facilitate their adsorption onto the metal surface. Under high-temperature conditions, iodide ions (I–) not only adsorb onto the metal surface, filling the gaps between MIB molecules, but also form a negatively charged layer. This negative layer subsequently attracts the positively charged quaternary ammonium cations of MIB, thereby enhancing the adsorption capability of MIB on the metal surface in high-temperature environments.
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POLYMER DEGRADATION AND STABILITY
·
2025
·
IF 7.4
Jianqi Lu,Wei Wu,Wenyao Wang,Biao Wu,Jinhong Deng,Jie Zhou,Xiaoli Zhou,Weiliang Dong,Min Jiang
Recycling of waste polyester-cotton blended fabrics (PCB) is confronted with challenges due to the different chemical properties of each component and their intertwined structure. Herein, PCBs were degraded into monomers through room-temperature dissolution-precipitation pretreatment and enzymatic depolymerization. Polyester was selectively dissolved and separated from PCB and then precipitated in anti-solvent. The influence of the dissolved PET concentration on the recovery, particle size, and crystallinity of precipitated PET was investigated. The precipitated PET exhibited nanometer size and low crystallinity of 7.8%, which significantly accelerated the enzymatic depolymerization. The separated cotton fibers from PCB were also enzymatically depolymerized into glucose. At last, real-world PCBs with different component ratios and colors were successfully converted through this approach. This research provides a promising method for closed-loop recycling of PCB wastes.
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WASTE MANAGEMENT
·
2025
·
IF 7.1
Li Zhao,Wenwen Qu,Xianzhi Hu,Futing Zi
Achieving efficient and selective gold recovery from electronic waste is a desirable approach for the sustainable utilization of existing rare metal resources. In this study, an ingenious positively charged trap based on azole-functionalized polymer (CMCPS-IMZ) was strategically designed and synthesized via solvothermal method for the precise capture of gold complex ions. By incorporating nitrogen-containing heterocyclic groups onto the CMCPS surface, the porous structure and large surface area promoted the formation of gold-binding sites, thereby enhancing adsorption efficiency. Specifically, CMCPS-IMZ exhibited exceptional Au(III) adsorption performance, with a maximum loading capacity of 323.08 mg/g, following pseudo-first-order kinetics and Freundlich isotherm models. Theoretical calculations and experimental analysis suggested that the electrostatic interactions between the RNH + group on CMCPS-IMZ and AuCl 4 - served as the primary driving force to realize the highly efficient gold recovery, as well as involved in weak intermolecular interactions. Furthermore, CMCPS-IMZ demonstrated remarkable stability over multiple adsorption–desorption cycles using 0.5 M SC(NH 2 ) 2 as the ideal eluent, underscoring its potential as a robust and sustainable platform for precious metals recovery. Notably, CMCPS-IMZ microspheres achieved a gold extraction efficiency exceeding 93.33 % even in the presence of high concentrations of interfering ions in actual e-waste leachate. This work provides valuable insights into the nature of ion affinity and selectivity, offering guidance for the rational design of advanced adsorbents with tailored binding sites for targeted ion capture.
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FREE RADICAL BIOLOGY AND MEDICINE
·
2025
·
IF 8.2
Jiansong Liu,Shuo Wang,Changyu Tao,Haoyun Liu,Yutong Mao,Xinhui Zhao,Kaiqi Cheng,Guanqun Mu,Meng Wang,Weibin Wang,Ence Yang,Jiadong Wang,Yang Yang
Peroxisomes are essential organelles that maintain cellular redox homeostasis. Although alternatively spliced variants of certain peroxisome-related genes have been identified, the regulatory mechanisms governing alternative splicing (AS) and its functional impact on peroxisomal redox homeostasis remain poorly understood. Here, we demonstrate that glucose starvation (GS) induces crotonylation of DEAD-box helicase 1 (DDX1), which is regulated by the crotonyltransferase general control non-repressed protein 5 (GCN5) and the decrotonylase histone deacetylase 1 (HDAC1). DDX1 crotonylation at the lysine 490 residue enhances its interaction with heterogeneous nuclear ribonucleoprotein K (HNRNPK), which mediates mutually exclusive AS of acyl-CoA oxidase 1 (ACOX1). The AS of ACOX1, driven by DDX1 crotonylation and HNRNPK, promotes the generation of peroxisomal ROS, thereby enhancing oxidative damage and ultimately suppressing colorectal cancer (CRC) cell proliferation. Our findings uncover a novel mechanism by which DDX1 crotonylation regulates the AS of peroxisome-related genes and mediates peroxisomal redox homeostasis. This discovery bridges a critical gap in our understanding of how posttranslational modifications (PTMs) of DEAD/DEXD box RNA helicases modulate gene AS and identifies a potential therapeutic target for colorectal cancer.
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PROGRESS IN ORGANIC COATINGS
·
2025
·
IF 7.3
Jianyuan Zhang,Yize Liu,Haonan Liu,Shun Zhang,Shuyi Liu,Zihua Wang,Zhanjian Liu,Huaiyuan Wang,Chijia Wang
In this study, nitrogen-doped carbon quantum dots with non-covalently functionalized imidazole groups on their surface were chemically grafted onto fly ash filler via hydrothermal synthesis and equivalent-volume impregnation. An epoxy composite coating was then prepared by spraying. The I-CFA filler uses citric acid as carbon source and imidazole as nitrogen source, and a large number of nitrogen-doped carbon quantum dots are grown in-situ in the fly ash surface and inside, thereby improving the compatibility of the filler and epoxy resin. In addition, when the coating is damaged, nitrogen-doped carbon quantum dots will be released, and the imidazole groups on their surface can act as corrosion inhibitors to chemically adsorb Fe atoms on the surface of the substrate, and a continuous complexation reaction can be formed to form a passivation protective film grown in situ, which is adsorbed on the surface of carbon steel, thus playing a good barrier effect and slowing down the erosion of corrosive media. Compared with pure epoxy coating, the impedance modulus of I-CFA composite epoxy coating after double modification is 1000 times higher at common temperature condition, and 10 5 –10 6 times higher at harsh CO 2 -rich high temperature and high pressure conditions. This study is expected to provide new insights into the preparation of fly ash coatings with unique functions.
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GREEN CHEMISTRY
·
2025
·
IF 9.2
Shibin Zhang,Yan Xu,Danni Zhang,Lishun Bai,Yue Liu,Ying He,Feiyan Yu,Chengjun Liu,Sijie Li,Zhi Chang
Aluminum metal batteries (AMBs), as a next-generation green energy system, have garnered significant attention due to their inherent safety, low cost, and environmental benignity. However, non-uniform aluminum deposition and dendrite growth during cycling lead to rapid battery failure, resulting in resource waste and environmental pollution. To enhance resource utilization and achieve aluminum metal batteries with high efficiency and long cycle life, this study proposes an eco-friendly soft ZnP-H2Im glass film fabricated via a melt-quenching process as a protective layer for the aluminum anode, which minimizes the use of hazardous substances and improves process sustainability. This material combines excellent mechanical flexibility, chemical stability, and ion transport regulation (via its sub-nanochannels), enabling homogeneous AlCl4− and Al2Cl7− migration and promoting uniform aluminum nucleation and deposition. As a result, Al//Al symmetric cells based on soft ZnP-H2Im-protected Al achieve record-breaking cycle lives of more than 10 000 hours at various areal capacities and current densities, far surpassing those of unmodified systems. In addition, after coupling the soft ZnP-H2Im-protected Al with two organic cathodes, tetrachlorobenzoquinone (TCQ) and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ), the AMBs demonstrate high capacity, high reversibility, and high stability, with a capacity retention of 95% after 200 cycles and 80% after 220 cycles, respectively. This study not only advances interfacial engineering for AMBs but also provides a potential reference for extending this eco-friendly coordination polymer vitrification strategy to other metal anode systems, providing a transformative approach for developing high-performance secondary batteries with enhanced resource efficiency.
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