Materials Chemistry Frontiers
·
2025
·
IF 6.4
Lei Xu,Wenjing Lou,Fan Xu,Yujiao Xie,Yue Hu,Liting Xie,Chengyue Zhang,Aochi Liu,Xinyu Miao,Zhiwei Hou,Wenyuan Ma,Qiyu Zhao,Jie Lin,Aiguo Wu,Tianan Jiang
Irreversible electroporation (IRE) has emerged as a promising therapeutic modality for pancreatic cancer. However, traditional IRE techniques rely on high-voltage electric fields and require precise alignment of multiple electrodes, which complicates the procedure and increases associated risks. To address these challenges, we developed a novel “bipolar” IRE electrode that combines both the cathode and anode into a single device, simplifying the procedure and potentially reducing operational risks. Additionally, we incorporated a conductive metal–organic framework (MOF) to enhance the electric field distribution of the electric field, thereby improving the efficacy of tumor ablation. Mechanistic studies revealed that this combined approach induces tumor cell apoptosis and improves the consistency of ablation outcomes. Both in vitro and in vivo experiments demonstrated that the bipolar electrode, in combination with the conductive MOF, achieved a significant apoptosis rate of 59.95% ± 2.41 in vitro and resulted in an 85.77% ± 0.21 reduction in tumor volume in in vivo models, without any adverse effects. This approach provides a more optimized and potentially more effective solution for treating pancreatic cancer.
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高影响因子
Nanoscale
·
2020
·Vol. 13
·期 1
·131-137
·
IF 6.895
Zehao Zhou,Jian Zhao,Zhenghan Di,Bei Liu,Zhaohui Li,Xuemin Wu,Lele Li
Despite the increasing usage of porphyrinic metal–organic frameworks (MOFs) for combination therapy, the controlled encapsulation of inorganic nanoparticle-based therapeutics into such MOFs with specific structures has remained a major obstacle for improved tumor therapy. Here, we report the synthesis of a mesoporous MOF shell on the surface of gold nanorods (AuNRs), wherein a single AuNR is captured individually in single-crystalline MOFs with a controlled crystallographic orientation, for combinational phototherapy against solid tumors. The core–shell heterostructures have the benefits of a mesoporous structure and photoinduced singlet oxygen generation behavior characterized by the porphyrinic MOF shell, together with the plasmonic photothermal conversion characteristic of AuNRs. We demonstrated that the AuNR@MOF nanoplatform enables an efficient tumor treatment strategy by combining photodynamic therapy and photothermal therapy. We should emphasize that such systems could have applications beyond the field of cancer therapy, like plasmonic harvesting of light energy to induce and accelerate catalytic reactions within MOFs and multifunctional nanocarriers for agricultural formulations.
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PubMed
高影响因子
JOURNAL OF POWER SOURCES
·
2025
·
IF 7.9
Yuhan Cui,Jing Sun,Yining Wang,Lijie Zhao,Jiawei Wang,Yunpeng Wu,Wenxi Zhang,Zengyuan Fan,Yuzhe Tang,Yue Song,Zhongmin Su
The slow kinetics and poor structural stability prevent 2D transition metal selenides from wide application in supercapacitors. However, as a representative of new two-dimensional materials, Ti 3 C 2 T X (MXene) has excellent transport properties and rich surface functional groups, which can well make up for the shortcomings of metal selenides. The optimized morphology engineering from a combination of MXene and 2D bimetallic selenide will bring the performance of supercapacitor electrode material to a new level. In this paper, MXene/Mn 0.8 Ni 0.2 Se composites are creatively prepared by ultrasonic stirring and solvothermal synthesis. The hierarchically layered composite electrode material composed of MXene nanosheets and selenide nanosheets is successfully synthesized and its electrochemical performance as electrode material for supercapacitors is studied. The results show water not only promotes the deprotonation of triethylamine to participate in coordination but also causes triethylamine to generate OH − , which makes it easier to form layered products and restrict the growth of NiMn-Metal Organic Framework (MOF) into a three-dimensional structure. Subsequently, during the selenization process, a small amount of water and disodium ethylenediaminetetraacetic acid are added to further promote the stability of the 2D/2D structure. The wavy hierarchically layered structure can shorten the diffusion path of metal ions and enhance electronic conductivity. As a supercapacitor material, under the current density of 1 A g −1 , the specific capacitance of MXene/Mn 0.8 Ni 0.2 Se is 1126 F g −1 . This capacity is higher than most selenide capacities reported to date. In addition, the energy density of the asymmetric supercapacitor constructed with activated carbon as cathode and Mn 0.8 Ni 0.2 Se as anode can reach 46.18 Wh kg −1 when the power density is 750 W kg −1 . The outstanding specific capacitance and high energy density endow it with great potential for practical application.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2023
·
IF 15.1
Hui Shu,Tingrun Lai,Shanli Wang,Mengyao Li,Haoyu Li,Ting Chen,Xuechun Xiao,Yude Wang
Paraquat is a highly toxic herbicide, and its residue in food poses a huge threat to human health. High-sensitivity detection of trace paraquat is crucial but challenging. Herein, we theoretically predicted that FeCo-MOF materials with Fe and Co dual active sites have potential interactions with paraquat. Moreover, a porous FeCo-MOF materials with Fe and Co dual active sites were in-suit constructed on the surface of foam nickel by self-assembly strategy, and used for the electrochemical detection of paraquat. The electrochemical detection results indicate that the prepared FeCo-MOF foam nickel electrode exhibited ultra-high detection sensitivity (113.85 μA nM −1 cm −2 ) and trace detection limit (0.16 nM) in a wide range of paraquat concentration (1.00 nM–5.00 mM). In addition, we successfully used this FeCo-MOF foam nickel electrode for the detection of paraquat in apples, human serum, and fresh tea leaves (detection recovery is 97.00 %–99.99 %). Furthermore, the density functional theory (DFT) and X-ray photoelectron spectroscopy (XPS) confirm that Fe and Co are active sites for detecting paraquat, and the interaction between Fe and Co promotes highly sensitive detection of trace paraquat. Therefore, this work provides strategies and comprehension for designing and modulating active sites at the microscopic level to improve sensitivity for detecting toxic pesticides.
研究领域:
环境科学
·
分析化学
·
毒理学
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Sijia Zhang,YiJingdan Zhang,Yaxin Zheng,Yingying Li,Ting Wang,Xiaohong Hou
The widespread clinical use of large-volume parenteral preparations (LVP) has raised serious concerns about the migration of additives and their degradation products from plastic packaging into LVP. The simultaneous migration of multiple additives exacerbates the toxic risks of combined exposure. However, simultaneous monitoring of multiple compounds in such complex matrices remains challenging. Here, a novel magnetic solid phase extraction (MSPE) coupled with ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was developed for the enrichment and determination three plasticizers, four UV stabilizers, five antioxidants, and degradation products in both plastic packaging and LVP. The MSPE adsorbent, a newly fabricated MOF-on-MOF composite designated MIL-88 A(Fe)-500C@ZIF-8-2, was prepared via carbonization followed by surfactant-assisted growth. It exhibited a high specific surface area (1043 m 2 ·g −1 ), a hierarchical pore structure (micropores of 1.88 nm and mesopores of 3.49/13.14 nm), abundant functional groups, and excellent hydrophobicity (contact angle 137.8°), which collectively enabled efficient multisite synergistic adsorption. Key extraction parameters were optimized, yielding optimal conditions of 15 mg adsorbent, 10 min adsorption (without pH adjustment), and elution with 1.5 mL acetonitrile for 10 min. Under the optimized conditions, the method demonstrated good linearity ( r > 0.99), low detection limits (0.03–1.1 ng·g −1 for infusion bottle, 0.03–1.3 ng·g −1 for infusion bag, and 1.2–31.0 ng·L −1 for LVP), high accuracy (71.4–98.6%), and precision (RSD < 9.1%). Multiple additives were detected in actual packaging and LVP samples. Adsorption experiments revealed that the adsorption process was well described by the pseudo-second-order and Langmuir isotherm models. The adsorption behavior likely involved synergistic effects of multiple intermolecular interactions, including hydrophobic forces, π-π interactions, hydrogen bonding, and weak electrostatic interactions. This work provided a powerful analytical tool for safeguarding drug quality and a versatile material platform for the extraction of trace contaminants from complex matrices.
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高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2024
·
IF 20.2
Lili Huang,Shengpeng Mo,Xin Zhao,Jiangjing Zhou,Xiaobin Zhou,Yanan Zhang,Yinming Fan,Qinglin Xie,Bing Li,Junhua Li
Herein, a core-shell structured Co 3 S 4 /NC@ZnS/NC heterojunction has been constructed via elaborately synthesizing metal-organic framework (MOF)-on-MOF precursors (ZIF-67@ZIF-8) and following controlled carbonization-sulfidation processes. The developed Co 3 S 4 /NC@ZnS/NC achieves higher performances for CO 2 photoreduction with water vapor towards CO (28.44 μmol g −1 h −1 ), CH 4 (1.93 μmol g −1 h −1 ) and C 2 H 4 (12.23 μmol g −1 h −1 ) in a continuous-flow condition under visible-light irradiation, which are significantly superior than those of Co 3 S 4 /NC and ZnS/NC. 13 CO 2 isotope tracer analysis verifies that CO, CH 4 and C 2 H 4 originate from the carbon source of CO 2 . Experiments and DFT calculations confirm that constructing an electron transport layer (ZnS/NC) in Co 3 S 4 /NC@ZnS/NC can contribute to a feasible channel for the enhanced separation and transfer of charge carriers. In heterojunction , non-bonding Co and Zn atomic pairs as adsorption sites synergistically participate in the CO 2 activation through the unique electron transport channel and acquire the lower energy barriers of COOH* formation. Moreover, in situ DRIFTS reveals the key intermediates and possible conversion pathways to main products. This work presents an attractive strategy to construct dual MOFs-derived metal sulfide heterojunctions for high-performance CO 2 conversion.
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高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2025
·
IF 4.1
Sumin Xu,Wenjing Liu,Jiajia Zhang,Jianying Qu
In this work, a MOF-on-MOF synthesis strategy was employed to successfully prepare (ZIF-8)-on-(CoCu-MOF) composites, which were further pyrolyzed at high temperature to obtain CoCu-CN nanomaterials. The morphological and structural properties of the materials were systematically investigated using SEM, FTIR, XRD and XPS. A novel sensor of CoCu-CN/GCE was constructed at a glassy carbon (GC) substrate, which exhibited excellent electrocatalytic activity to redox reactions of acetaminophen (PA) and p-aminophenol (4-AP). Under optimal conditions, the CoCu-CN/GCE sensor can be employed to detect simultaneously PA and 4-AP in the wider linear ranges of 0.05–270.00 μM and 0.05–170.00 μM, respectively with the lower detection limits of 0.020 μM and 0.019 μM respectively. Practical sample analysis for pharmaceutical and lake water gave satisfactory results. The proposed sensor displays excellent selectivity and stability with potential analytical applications
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2021
·
IF 8.128
Wenxiu Gu,Qian Li,Haiyan Zhu,Luyi Zou
The self-assembled Bi-based metal–organic framework microspheres (Bi-MOF-M) by nanorods were successfully constructed by the glycol-assisted solvothermal method . Using Bi-MOF-M as a homologous template, a petal-like Bi 2 MoO 6 (BMO) layer was grown in situ on its surface to facilely construct a chemically bonded heterojunction interface, realizing a micro/nano hierarchical flower spherical-like Bi-MOF-M/BMO heterojunction composite photocatalyst . The as-prepared series of Bi-MOF-M/BMO- x catalysts show higher visible light catalytic performance for tetracycline hydrochloride (TC) degradation. Among them, Bi-MOF-M/BMO-0.3 has the optimal catalytic activity, and the degradation efficiency can reach 93.6% within 60 min of light irradiation with superior mineralization ability and structural stability , and the degradation kinetic constant is 6.12 times that of Bi-MOF-M and 5.69 times that of BMO, respectively. The homologously grown Bi-MOF-M/BMO chemically bonded heterojunction not only effectively broadens the spectral absorption range and enhances the absorption intensity but also promotes the efficient separation of photogenerated carriers through forming a favorable interfacial electric field and well-matched energy band alignment. A reasonable mechanism for the visible light degradation of TC by the Bi-MOF-M/BMO composite catalyst with h + and 1 O 2 as the main reactive species is proposed. The micro/nano hierarchical structure of the Bi-MOF/BMO catalyst allows it to exhibit the easy recovery advantage of micron-scale materials while maintaining the high catalytic activity of the primary nano-components.
研究领域:
环境科学
·
材料科学
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高影响因子
CATALYSIS LETTERS
·
2021
·Vol. 152
·期 4
·1160-1169
·
IF 3.186
Cheng Lin,Cao Liumei,Ren Hao,Guo Qiaoqiao,Deng Huifang,Li Yiming
The construction of a multifunctional catalyst for multistep sequential\tandem reactions at the molecular level faces a formidable challenge. Multivariate (MTV)-MOFs can provide a facile and tunable platform for rationally designing such multifunctional catalysts via grafting different catalytic groups on the bridging ligands. However, the related investigations are still limited. Here, Pd(II) and l -proline are metalated and decorated to organic linkers, respectively, to build a MTV-MOF, which is then successfully applied to sequential Suzuki Coupling/asymmetric Aldol reactions with satisfied coupling performance (yields up to 99%) and good enantioselectivities ( ee anti up to 98%). Inductively coupled plasma optical emission spectrometer (ICP-OES) measurements of the supernatant and hot leaching test suggest the heterogeneous nature of the catalyst. Macrosubstrate tests verify that the reaction occurs inside the pores of the MOF. The heterogeneous catalyst can maintain structural stability and catalytic activity within three cycles. Graphic Abstract Versatile Pd(II) and l -proline were metalated and decorated, respectively, into stable UiO-67 to construct bifunctional and heterogeneous multivariate MOF catalyst, which displayed efficient and recyclable catalytic activity in sequential Suzuki Coupling/asymmetric Aldol reactions.
研究领域:
化学
·
材料科学
·
催化领域
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高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2024
·Vol. 31
·期 6
·9764-9783
·
IF 0
Zhang Zhenhong,Zhong Yuye,Sun Peng,Zhao Pingping,Li Houbin,Liu Xinghai
The development of effective and practical adsorbents for eliminating pollutants still remains a significant challenge. Herein, we synthesized a novel magnetically separable composite, Co 0.6 Fe 2.4 O 4 /MIL-101-NH 2 , through the in-situ growth of MIL-101-NH 2 on magnetic nanoparticles, designed specifically for the removal of Congo red (CR) from aqueous solutions. MIL-101-NH 2 possessed high BET surface area (240.485 m 2 •g −1 ) and facile magnetic separation function and can be swiftly separated (within 30 s) through an external magnetic field post-adsorption. The investigation systematically explored the influence of crucial parameters, including adsorbent dosage, pH, adsorption duration, temperature, and the presence of interfering ions, on CR adsorption performance. Findings indicate that CR adsorption adheres to the pseudo-second-order (PSO) kinetic model and the Langmuir isotherm model. Thermodynamic analysis reveals the spontaneity, endothermic nature, and orderly progression of the adsorption process. Remarkably, the adsorbent with 0.1 g•L −1 boasts an impressive maximum adsorption capacity of 1756.19 mg•g −1 for CR at 298.15 K, establishing its competitive advantage. The reuse of the adsorbent over 5 cycles remains 78% of the initial adsorption. The CR adsorption mechanisms were elucidated, emphasizing the roles of π-π interactions, electrostatic forces, hydrogen bonding, and metal coordination. Comparison with other dyes, such as methylene blue (MB) and methyl orange (MO), and exploration of adsorption performance in binary dye systems, demonstrates the superior capacity and selectivity of this adsorbent for CR. In conclusion, our magnetically separable metal–organic framework (MOF)based composite presents a versatile and effective solution for CR removal, with promising applications in water treatment and environmental remediation. Graphical
研究领域:
环境科学
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材料科学
·
化学工程
·
纳米技术
·
物理化学
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WATER AIR AND SOIL POLLUTION
·
2025
·Vol. 236
·期 13
·1-19
·
IF 3
Zhang Xia,Zhou Mengqin,Wan Xiu,Liu Xi,Hao Shixiong,Cheng Chunru,Xiao Zhongming,Wang Yongfan
To address the challenges of titanium dioxide's low utilization of visible light, easy recombination of photogenerated charges, and insufficient interfacial contact when integrated with other semiconductors to form heterojunctions, a novel, simple, and easy hybrid MOF template-directed method was developed to enhance the interaction between oxide and support, thereby constructing In 2 O 3 @TiO 2 - x (IT- x ) composites with tightly contacted heterojunction interfaces. After 120 minutes of exposure to visible light, the IT-30% realized a 91.98% degradation rate for tetracycline in wastewater with an initial concentration of 30 mg/L, which is 1.46, 3.39, and 2.07 times higher than that of bare TiO 2 , bare In 2 O 3 , and Degussa-P25, respectively. After 5 cycles (10 h), the IT-30% photocatalyst still maintained high photocatalytic activity with a 14.47% decline in tetracycline degradation efficiency. The experiments on free radical trapping and electromagnetic spin resonance (ESR) revealed that the superoxide radical is the primary active substance in the tetracycline photocatalytic degradation. SEM, HRTEM, and XRD characterization techniques were utilized to demonstrate the successful preparation of hollow composites. The results of BET, UV-Vis DRS, XPS, photoluminescence (PL), and electrochemical impedance spectroscopy (EIS) indicate that the high photocatalytic activity of the prepared IT-30% composite is ascribed to its large specific surface area, strong capacity for visible light absorption, generate abundant oxygen vacancies generated in the composites, and efficient separation and migration of photogenerated carriers. In addition, a possible degradation pathway for tetracycline was proposed according to the HPLC-MS test results of intermediate products.
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高影响因子
FUEL
·
2025
·
IF 7.5
Xiaomei Qin,Chengchao Liu,Xiaoyun Qin,Jianbo Zhao,Huishi Guo,Yanghai Gui,Jingfei Xiao,Zhen Zhang
In this study, activated biochar (ABC) sourced from solid biowaste was prepared using wheat straw as the carbon source. The ABC was then used as a carrier for the in-situ growth of Cu-MOF-74, which was subsequently pyrolyzed at high temperatures to prepare Cu-MOF derivative-modified porous biochar composites Cu/ABC-T (T = 700–1000 °C) with a uniform distribution of Cu species on the biochar surface. The effect of pyrolysis temperature on the as-prepared Cu/ABC was investigated. The experimental results showed that Cu/ABC-900 exhibited the optimal adsorption performance for DBT, confirming that the uniform distribution of Cu on the biomass carbon surface after high-temperature pyrolysis effectively enhanced the desulfurization performance. Specifically, the as-prepared Cu/ABC-900 achieved an adsorption efficiency of nearly 90 % for 1000 ppm DBT, with an adsorption equilibrium time of only 5 min and a maximum adsorption capacity of 19.70 mg S·g −1 . The adsorption process of DBT by Cu/ABC followed the pseudo-second-order kinetic model and Langmuir adsorption model. The adsorption performance of Cu/ABC-900 for different sulfides followed the order: DBT > BT > TH. Furthermore, the adsorption efficiency of Cu/ABC-900 for DBT did not exhibit any significant decline after five regeneration cycles, indicating the excellent regenerability and great potential for practical applications. This work provides a new approach to utilizing carbon-based adsorbents for deep desulfurization, which is beneficial for cost-effective fuel cleaning.
研究领域:
环境科学
·
能源化学
·
材料科学
·
化学工程
·
燃料净化
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高影响因子
危险品化学品经营许可证（带存储）