JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY
·
2014
·
IF 2.063
Jixiang Wang,Jianming Pan,Yijie Yin,Runrun Wu,Xiaohui Dai,Jiangdong Dai,Lin Gao,Hongxiang Ou
Thermal-responsive and magnetic molecularly imprinted polymers (TMMIPs) based on Fe 3 O 4 @carbon (Fe 3 O 4 @C) were prepared by free radical polymerization and applied to selective adsorption and controlled release of 2,4,5-trichlorophenol (2,4,5-TCP) from aqueous solution. TMMIPs were composed of multilayer structure, and exhibited magnetic sensitivity, magnetic stability and thermal stability (especially below the. The reversible transform of mean diameter resulted from the change of testing temperature, indicating the thermo-responsive properties of TMMIPs. Selective adsorption and controlled release of 2,4,5-TCP were also investigated at 25 °C and higher temperature (such as 45 °C and 60 °C), respectively.
研究领域:
环境科学
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材料化学
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高分子科学
·
分析化学
·
水处理
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2017
·Vol. 135
·期 13
·46052
·
IF 1.86
Cong Jia,Xiao Zhang,Yufeng Li,Yanghui Jiang,Min Zhang,Panfang Lu,Hongkun Chen
A novel controlled release fertilizer was developed using interpenetrating polymer network (IPN) as the coating material. The IPN was successfully sprayed on the surface of the urea particles to form IPN-coated fertilizers (IPNCU) for controlled nitrogen release. The IPN was synthesized by bio-based polyamide (PA) from d -glucaric acid and epoxy (EP) through network interpenetrating. The chemical structure and microscopic morphology characteristics of IPN were examined by Fourier transform infrared spectroscopy, 1 H-nuclear magnetic resonance, and scanning electron microscopy. The property of IPN with the different PA/EP mass ratios were investigated and compared with that of EP-coated fertilizers (EPCU). The nutrient release behaviors of IPNCU in water and soil were detected. The results showed that the IPNCU with 5% PA content increased the nitrogen release longevity by 41 days, raised the water contact angle of surface by 23.9°, and then significantly slowed the nitrogen release rate of the IPNCU. The nutrient release mechanism of IPNCU was discussed in detail. This work indicated that the environment-friendly IPN with superior controlled release properties could be especially useful in horticultural and agricultural applications. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135 , 46052.
研究领域:
聚合物科学
·
农业化学
·
环境科学
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ACS Omega
·
2019
·
IF 2.584
Yangjie Shao,Dongqi You,Yiting Lou,Jianhua Li,Binbin Ying,Kui Cheng,Wenjian Weng,Huiming Wang,Mengfei Yu,Lingqing Dong
Naringin, a Chinese herbal medicine, has been demonstrated to concentration-dependently promote osteogenic differentiation of mesenchymal stem cells (MSCs). However, it remains a challenge to load naringin on coatings for osteogenesis and further control the release kinetics. Here, we demonstrated that the release behavior of naringin on rutile nanorod films could be controlled by either mixing naringin with gelatin methacryloyl (GelMA) before spinning onto the films or soaking the obtained GelMA-incorporated films with the naringin solution to achieve the distinct degradation-type release and diffusion-type release, respectively. We further revealed that the naringin-loaded coatings facilitated adhesion, proliferation and late differentiation, and mineralization of MSCs. Our findings provided a novel strategy to engineer the coatings with controlled release of naringin and emphasized the bioactivity of naringin for the osteogenic differentiation of MSCs.
研究领域:
生物材料学
·
细胞生物学
·
组织工程学
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PubMed
高影响因子
MACROMOLECULAR MATERIALS AND ENGINEERING
·
2022
·Vol. 307
·期 7
·2100983
·
IF 4.402
Ying Cao,Jianmin He,Jianhua Wu,Xiaoyu Wang,Wei Lu,Jingyu Lin,Yiting Xu,Guorong Chen,Birong Zeng,Lizong Dai
Inspired by the various applications of self-assembled amphiphilic polymers in aqueous solution, a novel “semi-amphiphilic” copolymer is designed, which can self-assemble in organic systems by taking advantage of the compatibility difference between epoxy and the units with different structures in the polymer chains. A novel kind of polymer, poly(syringaldehyde methacrylate)-co-poly(dopamine methacrylate) is prepared by reversible addition-fragmentation chain transfer polymerization, which contains aldehyde groups and is further used to prepare the polymer/guanine conjugate by forming the Schiff base. The polymer/guanine conjugate is semi-amphiphilic, since the compatibility between dopamine methacrylate unit and epoxy is better than that between syringaldehyde methacrylate and epoxy, and therefore assemblies are formed in the organic system when it is added into the epoxy resin to prepare the anti-corrosive coating. The imine linkage is responsible for the pH-controlled release of the corrosion inhibiters, namely guanine, from the core of the assemblies. The self-assembled behaviors of the semi-amphiphilic copolymer in epoxy are investigated by dynamic light scattering and scanning electron microscopy. The stable encapsule and controlled-release of the inhibitors are confirmed by UV spectrophotometry. The properties of the smart coatings are comprehensively studied.
研究领域:
材料科学
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化学工程
·
防腐蚀技术
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DOI
高影响因子
MACROMOLECULAR CHEMISTRY AND PHYSICS
·
2021
·Vol. 222
·期 13
·2000365
·
IF 2.527
Qiong Guo,Jiangtao Liu,Hong Yang,Zhongli Lei
Stimuli-responsive chemical bonds have already been widely applied to construct nanomaterials, however, such materials rarely have great amounts of responsive groups and stable structures. Herein, a triple-stimuli-responsive interface-cross-linked (ICL) copolymer which is synthesized via Cu(I)-catalyzed azide-alkyne cycloaddition click polymerization and atom transfer radical polymerization (ATRP), is reported. N, N′-bis(bromoacetyl) cystamine is used for intramolecular crosslinking of the linear polymer chains. The ο-nitrobenzyl groups, peroxalate ester bonds, disulfide bonds, and triazole units are regularly and repeatedly arranged in the hydrophobic blocks, therefore enabling the polymer a large amount of responsive chemical bonds. The polymer self-assembles into spherical micelles with uniform size in deionized water. Using hydrophobic dye Nile red (NR) as a model drug to evaluate the effect of release in vitro, the multi-stimuli-sensitive release properties of the ICL micelles are investigated in detail by means of UV–vis, transmission electron microscopy, dynamic light scattering, and fluorescence spectrophotometry, and the results indicate the ICL micelles can respond to the photo, oxidation, or reduction responsiveness either independently or synergistically. Furthermore, the cross-linked structure enhances the stability of the micelles and rarely impacts the total amount of drug release. The research may have applications in the field of drug delivery systems for cancer therapy.
研究领域:
材料科学
·
药学
·
生物医学工程
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SCIENCE OF THE TOTAL ENVIRONMENT
·
2017
·
IF 4.9
Tao Zhou,Yan Wang,Sheng Huang,Youcai Zhao
Nearly 1.3 billion tons of food are discarded annually in the production process. In this study, a novel slow-release nitrogen fertilizer with water absorbency was developed using leftover rice and crosslinking methods. Urea was incorporated as the nitrogen source in a leftover rice-g-poly(acrylic acid)/montmorillonite (LR-g-PAA/MMT) network, and then the leftover rice-g-poly(acrylic acid)/montmorillonite/Urea (LR-g-PAA/MMT/Urea) retained in the soil, and used as the loss control agent for water and nutrients. Variables including concentrations of acrylic acid , montmorillonite , N,N´-methylenebis acrylamide (MBA), and potassium persulfate (KPS) were investigated. Samples were with a water absorbency of 102.6 g/g in distilled water and 25.1 g/g in 1.0 wt% NaCl solution under optimized conditions. Swelling measurements and water-retention indicated that higher-covalent cations would aggregate the hydrogels and decrease swelling. Investigating leaching behavior showed that these samples have the potential to carry the necessary nitrogen (N). The results demonstrated that the LR-g-PAA/MMT/Urea had a low leaching losses of N (19.7%) compared with pure urea (52.3%). Therefore, the developed fertilizer may be widely applicable in agriculture and horticulture , and could provide a new platform for reusing leftover rice.
研究领域:
农业化学
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环境材料
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可持续农业
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土壤科学
·
高分子科学
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高影响因子
Journal of Functional Biomaterials
·
2023
·Vol. 14
·期 5
·278
·
IF 4.8
Chengqun Yu,Abid Naeem,Yali Liu,Yongmei Guan
Oxidants play a crucial role in the development of oxidative stress, which is linked to disease progression. Ellagic acid is an effective antioxidant with applications in the treatment and prevention of several diseases, since it neutralizes free radicals and reduces oxidative stress. However, it has limited application due to its poor solubility and oral bioavailability. Since ellagic acid is hydrophobic, it is difficult to load it directly into hydrogels for controlled release applications. Therefore, the purpose of this study was to first prepare inclusion complexes of ellagic acid (EA) with hydroxypropyl-β-cyclodextrin and then load them into carbopol-934-grafted-2-acrylamido-2-methyl-1-propane sulfonic acid (CP-g-AMPS) hydrogels for orally controlled drug delivery. Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC) were used to validate ellagic acid inclusion complexes and hydrogels. There was slightly higher swelling and drug release at pH 1.2 (42.20% and 92.13%) than at pH 7.4 (31.61% and 77.28%), respectively. Hydrogels had high porosity (88.90%) and biodegradation (9.2% per week in phosphate-buffered saline). Hydrogels were tested for their antioxidant properties in vitro against 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2′-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS). Additionally, the antibacterial activity of hydrogels was demonstrated against Gram-positive bacterial strains (Staphylococcus aureusandEscherichia coli) and Gram-negative bacterial strains (Pseudomonas aeruginosa).Keywords:hydrogels;polyphenol;phytoconstituents;inclusion complexation;anti-oxidants;bioavailability
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高影响因子
EUROPEAN POLYMER JOURNAL
·
2023
·
IF 6
Lu Wang,Xin Gang,Yu Xiao,Yi Ren,Jianhong Wang,Baolong Niu,Wenfeng Li
In this study, CMCS-CuO nanoparticles were added to the SA matrix by blending method to prepare SA/CMCS-CuO composite microspheres. The chemical structure and morphology of the composite beads were characterized. The results showed that there was a certain molecular interaction between CMCS-CuO NPs and SA matrix. The swelling experiment showed that with the increase of the mass of CMCS-CuO NPs, the maximum swelling ratio of gel microspheres decreased from 49.83% to 38.2%, and the time to reach the maximum swelling ratio also increased from 8 h to 11 h. Cytotoxicity test, hemolysis test, and cell migration test showed that the composite microspheres had good biocompatibility. Curcumin was added to the composite bead matrix by the blending method, and curcumin-loaded SA/CMCS-CuO composite beads were prepared by the crosslinking method. In vitro release experiments showed that SA/CMCS-CuO composite microspheres had good pH sensitivity, and the addition of CMCS-CuO NPs prolonged the in vitro release time of cur. It has certain application potential in the field of drug release.
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JOURNAL OF HAZARDOUS MATERIALS
·
2022
·
IF 14.224
Shuxuan Wu,Sheng Deng,Fu Xia,Xu Han,Tianyu Ju,Han Xiao,Xiangjian Xu,Yu Yang,Yonghai Jiang,Beidou Xi
The increasing risk of organic contamination of groundwater poses a serious threat to the environment and human health, causing an urgent need to develop long-lasting and adaptable remediation materials. Controlled-release materials (CRMs) are capable of encapsulating oxidants to achieve long-lasting release properties in aquifers and considered to be effective strategies in groundwater remediation . In this study, novel hydrogels (ASGs) with thermosensitive properties were prepared based on agarose and silica to achieve controlled persulfate (PS) release. By adjusting the composition ratio, the gelation time and internal pore structure of the hydrogels were regulated for groundwater application, which in turn affected the PS encapsulated amount and release properties. The hydrogels exhibited significant temperature responsiveness, with 6.8 times faster gelation rates and 2.8 times longer controlled release ability at 10 ℃ than at 30 ℃. The ASGs were further combined with zero-valent iron to achieve long-lasting degradation of the typical nitrobenzene compound 2,4-dinitrotoluene (2,4-DNT), and the degradation performance was maintained at 50 % within 14 PV, which was significantly improved compared with that of the PS/ZVI system. This study provided new concepts for the design of controlled-release materials and theoretical support for the remediation of organic contamination.
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高影响因子
Scientific Reports
·
2022
·Vol. 12
·期 1
·1-13
·
IF 4.996
Luo Meng,Lin Juntao,Zhou Xinhua,Pu Xia
This study provides a promising controlled release form of nuclear polyhedrosis virus (NPV) for targeted control of lepidopteran pests. However, the application of NPV is limited due to its sensitivity to UV inactivation. This study investigated the anti-UV properties of microcapsules of SeMNPV occlusion bodies (OBs) encapsulated by calcium alginate (CA), and also the influence of the modification of CA by chitosan (CS), whey protein (WP), and polydopamine (PDA). These capsules were used to deliver, in a controlled release manner virions under alkaline pH conditions. Characterization of the structure, morphology, particle size, encapsulation efficiency, contact angle, insecticidal activity, UV resistance and in vitro release of the microcapsules was conducted. The modified microcapsules had better sphericity, and were devoid of SeMNPV OBs on the surface. The encapsulation rate was 84.76 ± 0.59%. PDA@CA-NPV had the highest wettability and the contact angle was 74.51 ± 0.53°. The 50% lethal concentration values (LC 50 ) of CA-NPV, CS@CA-NPV, WP@CA-NPV and PDA@CA-NPV were 11.5, 10.7, 10.5 and 1.2 times that of SeMNPV OBs alone. The modified microcapsules all improved the anti-UV performance of the virus, and PDA@CA-NPV was the most UV-resistant. Using qPCR, it was observed that under alkaline conditions, a large number of virions were released from PDA@CA-NPV, CA-NPV and SeMNPV OBs. Microencapsulated virus under alkaline conditions did not change the release pattern of virions.
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POLYMER BULLETIN
·
2023
·
IF 3.2
Faqir Yahya,Chai Yunlong,Jakhar Ali Murad,Wu Sanmei,Luo Tong,Liao Shiyu,Kalhoro Mohammad Talib,Li Linqiu,Kaleri Abdul Rasheed,Tan Chengjia,Ma Jiahua,Zhang Qiling,Cao Shidong,Adeel Mohammad
The present study was undertaken with the aim of evaluating the ginger essential oil potential and its urea-loading efficacy in the preparation of control-releasing chitosan microspheres. The ginger oil for hydro-distillation was extracted by applying Clevenger apparatus, chemical composition was characterized by FTIR, and the GC-MS was used to identify the oil compounds. Urea-loaded chitosan microsphere formulations were formulated through modified emulsification and cross-linking procedure. The various factors and levels related to preparation of urea-loaded chitosan microspheres were evaluated using response surface test. The present study was also an effort to observe the yield and content of nitrogen. Additionally, FTIR and SEM were applied to characterize the microspheres. The results show the yield of ginger oil as 6.0%. Main compounds identified by GC-MS were gingerol, decanal, isoshogaol, octanal, and others. FTIR also showed that some typical bands appeared in ginger oil. The nitrogen content % in urea-loaded microspheres showed a significantly higher value in proportion to higher oil volume and cross-linking. However, by decreasing the amount of urea and enhancing acetic acid, nitrogen content was decreased. The lower oil concentrations improved the microsphere surface structure and morphology. Response surface analysis showed that the optimum preparation conditions are as follows: 2.094% of Span 80, 2.302% of acetic acid, and cross-linking agent ratio of formaldehyde to glutaraldehyde 1:8.15. Under these conditions, the theoretical value of nitrogen content of urea-loaded chitosan microspheres was 4.683%. According to release test, the urea diffused uniformly in the microspheres after 48 h. It is concluded that the use of ginger oil in control release of fertilizers is the right option in the formulations of control-releasing micro-fertilizers.
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COLLOIDS AND SURFACES B-BIOINTERFACES
·
2023
·
IF 5.8
Shengyuan Ye,Yang Cheng,Zheng Guo,Xingguo Wang,Wei Wei
This study aimed to prepare single-component LNPs with sugar alcohol fatty acid monoesters for temperature-controlled release. In total, 20 kinds of lipids with a series of sugar alcohol head groups (ethylene glycol, glycerol, erythritol , xylitol and sorbitol) and fatty acyl tails (12:0, 14:0, 16:0 and 18:0) were synthesised via lipase-catalysed esterification . Their physicochemical properties and upper/lower critical solution temperature (LCST/USCT) were analysed. Two groups of mixed lipids, 78 % ethylene glycol lauric acid monoester + 22 % sorbitol stearic acid monoester (LNP-1) and 90 % ethylene glycol lauric acid monoester + 10 % xylitol myristic acid monoester (LNP-2), had LCST/USCT of approximately 37 °C, which formed empty LNPs using the emulsification−diffusion method. These two mixed lipids were prepared for LNPs loaded with curcumin , showing high encapsulation (>90 %), mean particle sizes of approximately 250 nm and low polydispersity index (≤0.2). These lipids have the potential for tailor-made LNPs achieving thermo-responsivity in delivering bioactive agents and drugs.
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危险品化学品经营许可证（带存储）