JOURNAL OF MOLECULAR LIQUIDS
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2022
·
IF 6.633
Fulin Li,Lihong Deng,Qiwei Xu,Ke Yuan,Hang Song
1,8-Cineole has anti-inflammatory, antibacterial and physiological properties and its high purity is important to application. However, 1,8-cineole usually mixes with monoterpene hydrocarbons in plant essential oils and they are difficult to separate via distillation due to their close boiling points. In this study, a series of lactic acid (LA) based deep eutectic solvents (LaDESs) were formed and used in liquid–liquid separation of 1,8-cineole and monoterpene hydrocarbons. LaDES formed by LA and tyrosine (Tyr) showed 24.8 selectivity of 1,8-cineole to γ-terpinene at 25 ℃. Synergists or auxiliary extractant such as tert -butanol can improve the distribution coefficient but reduce the selectivity. Some effect factors to the extraction were investigated and 99% purity of 1,8-cineole was achieved in the final product. The extraction thermodynamic parameters and kinetic process were studied. The re-extraction and the LaDES recovery were carried out satisfactorily. It further proved that the separation of 1,8-cineole from α-pinene, α-terpinene and ρ-cymene could be performed well with the LaDES respectively. Liquid-liquid extraction separation of 1,8-cineole and γ-terpinene has the advantages of low energy consumption, high selectivity and safety. It would provide an alternative strategy for separating 1,8-cineole and monoterpene hydrocarbons whose boiling points are close.
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2022
·
IF 24.319
Qiu Xu,Chungang Wang,Zongling Shang,Chao Zhang,Xinchao Wang,Qiang Liu,Lingling Dang,Yanchun Liu,Fengyu Zhao
The activation and ring opening reaction of lactone bond is of great significance in biomass utilization. Cu-based catalysts are widely used in the biomass hydrogenation processes, in which the effect of oxide promoters on Cu catalysts is one of the most attractive research topics. Herein, the transformation of lactones to diols over Cu/Al 2 O 3 and CuLa x /Al 2 O 3 catalysts was studied and the promoting role of LaO x has been discussed. The CuLa 0.25 /Al 2 O 3 catalyst showed outstanding catalytic performance with high 1,4-butanediol yield of > 90 %, and it also showed high efficiency for the hydrogenation of series of five- and six-membered lactones (γ-butyrolactone, γ-valerolactone, δ -hexalactone, etc) to diols. Based on the comprehensive analysis of the XRD, TEM, TPR, XPS, low temperature CO-DRIFT results, the crucial contribution of LaO x species in promoting the selectivity and stability of catalysts were investigated in detail. The presence of LaO x species not only results in the formation of Cu + -LaO x interfacial active sites, which facilitate the adsorption and activation of lactones, but also promotes the stability of catalyst.
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APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Wenfang Miao,Shaopeng Li,Xingru Cao,Enmin Lv,Hongtao Yu,Xuefeng Zhang,Xinglong Dong
The sluggish kinetics of oxygen reduction reaction at the cathode is one of the obstacles of the next-generation energy conversion system such as fuel cell and Zn-air battery. Here, a simple pyrolysis method was used to transform delignification-treated balsa wood into nitrogen-doped porous layered carbon materials. γ-Fe 2 O 3 nanocrystals were supported on N-doped wood-derived carbon materials. The prepared Fe 2 O 3 -CW 1000 catalyst exhibits superior ORR performance with a high onset potential of 0.98 V RHE in alkaline environment. This is consistent with the potential of commercial Pt/C. The superior ORR activity is attributed to the fact that γ-Fe 2 O 3 nanoparticles promote the activity of Fe-N x sites. And the N-enriched porous carbon matrix facilitates the faster electron movement on the catalyst surface and the full exposure of the active sites.
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MOLECULES
·
2022
·Vol. 27
·期 10
·3068
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IF 4.927
Wenyun Wang,Song Liu,Mingyan Yan
Salinity is one of the major abiotic stresses limiting crop growth and productivity worldwide. Salt stress during germination degenerates crop establishment and declines yield in wheat, therefore alleviating the damage of salt stress to wheat seedlings is crucial. Chitooligosaccharide (COS) was grafted with γ-aminobutyric acid based on the idea of bioactive molecular splicing, and the differences in salt resistance before and after grafting were compared. The expected derivative was successfully synthesized and exhibited better salt resistance-inducing activity than the raw materials. By activating antioxidant enzymes such as superoxide dismutases (SOD), catalase (CAT) and phenylalanine ammonia-lyase (PAL) and subsequently eliminating reactive oxygen species (ROS) in a timely manner, the rate of O−2production and H2O2content of wheat seedlings were reduced, and the dynamic balance of free radical metabolism in the plant body was maintained. A significantly reduced MDA content, reduced relative permeability of the cell membrane, and decreased degree of damage to the cell membrane were observed. A significant increase in the content of soluble sugar, maintenance of osmotic regulation and the stability of the cell membrane structure, effective reduction in the salt stress-induced damage to wheat, and the induction of wheat seedling growth were also observed, thereby improving the salt tolerance of wheat seedlings.Keywords:chitooligosaccharide;γ-aminobutyric;salt stress
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BIOSENSORS & BIOELECTRONICS
·
2022
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IF 12.545
Yanli Zhou,Jiaxiang Liu,Hui Dong,Zi Liu,Lu Wang,Qiaoxia Li,Jianhua Ren,Yintang Zhang,Maotian Xu
Interferon-gamma (IFN- γ ) is one kind of crucial inflammatory cytokines, and its expression level is closely associated with various disease progressions. This work addresses the development of a sensitive and specific electrochemical assay for detection of IFN- γ by combing the recognition unit of aptamer with the signal reporter of target-induced silver nanoclusters (AgNCs). For biosensor preparation, the gold nanoparticles (AuNPs) immobilized on the amine-terminated electrode surface provided electrochemical interfaces for the self-assembly of C-rich modified aptamers. Then, the aptamer recognized IFN- γ and the free aptamer hybridized with conjugated DNA sequences . After the nuclease-catalyzed cleavage of DNA duplex, in situ-generated AgNCs in the C-rich template was utilized as the electrochemical indicator for IFN- γ detection. The present method demonstrated a good performance for detection of IFN- γ with a low detection limit of 1.7 pg mL −1 . This aptasensor was verified to be applied for the evaluation of IFN- γ secreted by cell.
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ACS Applied Materials & Interfaces
·
2023
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IF 9.5
Xiaoyang Chen,Jian Chen,Yijie Liu,Yang Liu,Yun Gao,Siwei Fan,Xiangxi He,Xiaohao Liu,Chao Shen,Yong Jiang,Li Li,Yun Qiao,Shulei Chou
Metal–CO2 batteries, especially Li–CO2 and Na–CO2 batteries, are regarded as ideal new-generation energy storage systems owing to their high energy density and extraordinary CO2 capture capability. However, the advancement of metal–CO2 batteries is still at an early stage. The problems caused by accumulation of carbonates during charge–discharge cycles, such as large polarization and poor reversibility, restrict their practical application. Therefore, designing efficient catalysts is crucial for promoting the decomposition of carbonate to improve the electrochemical performance of metal–CO2 batteries. Herein, we first adopted sea urchin-like γ-MnO2 as the cathode material for Li/Na–CO2 batteries. Benefiting from the unique structure and excellent catalytic activity of γ-MnO2, the as-prepared Li–CO2 and Na–CO2 batteries can achieve low overpotentials of 1.28 and 1.36 V, respectively, at a current density of 100 mA g–1 with a cutoff capacity of 1000 mA h g–1. The overpotentials are lower than those of most of the state-of-the-art catalysts in previous reports. After 100 and 50 cycles of Li–CO2 and Na–CO2 batteries, respectively, their charging termination voltages remain at around 4.1 and 3.9 V, respectively; such a low charging platform indicates the excellent catalytic activity of the γ-MnO2 cathode on the discharge products. Our findings offer a promising guideline to design efficient electrocatalysts for high-performance metal–CO2 batteries.
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Crystals
·
2023
·Vol. 13
·期 5
·810
·
IF 2.7
Ruonan Tian,Huai Tan,Gang Chen,Hongtao Guan,Chengjun Dong,Zongyou Yin
Although individual γ-Fe2O3and α-Fe2O3have been widely fabricated for gas sensors, their mixed phase of α/γ-Fe2O3might deliver excellent sensing properties. In this study, a facile solvothermal method was used to fabricate Fe-alkoxide. After thermal treatment, it was converted into γ-Fe2O3, α-Fe2O3and their mixed-phase α/γ-Fe2O3with a nanosheets-assembled flower-like structure. We studied the influence of calcination temperature on the phase and sensing properties on acetone detection. The α/γ-Fe2O3which annealed at 400 °C included 18% α-Fe2O3and it exhibited excellent sensing performance towards acetone compared to that of γ-Fe2O3and α-Fe2O3. It showed a response of 353 to acetone with a concentration of 200 ppm, and a low limit of detection of 0.5 ppm at 160 °C. In addition, the change in responses with acetone concentration from 50 to 200 ppm shows a good linear relationship. Moreover, this material has good reproducibility and selectivity as well as a fast response time of 22 s and recovery time of 14 s to 200 ppm. Therefore, our mixed phase of α/γ-Fe2O3possesses great prospects for acetone detection.Keywords:Fe2O3;phase;gas sensor;acetone;sensing performance
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Advanced Healthcare Materials
·
2026
·
IF 11
Yiru Ding,Youyan Chen,Ziqian Zhao,Hexin Xie
Photodynamic therapy (PDT) is a minimally invasive cancer treatment, but its clinical translation is limited by the intrinsic conflict between hydrophilicity for systemic delivery and hydrophobicity for cellular uptake and retention. Here, we report a γ-glutamyltransferase (GGT)-activatable, hydrophilicity-switchable, and self-immobilizing near-infrared photosensitizer, GGT-PS2 . Initially hydrophilic and photoinactive, GGT-PS2 undergoes enzymatic cleavage by tumor-associated GGT, triggering a hydrophilic-to-hydrophobic transition and generating a reactive quinone methide intermediate for covalent immobilization. This process simultaneously activates near-infrared fluorescence and singlet oxygen production. In vitro studies demonstrate GGT-specific activation, efficient protein binding, and enhanced photodynamic performance compared to control analogs. In a HeLa tumor xenograft model, GGT-PS2 achieves selective tumor accumulation and prolonged retention, resulting in complete tumor regression after a single intravenous administration with light irradiation, without observable toxicity or recurrence. This “one-to-multi” design provides an effective strategy to overcome the solubility–retention trade-off, offering a promising platform for precision PDT.
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Journal of Analytical Methods in Chemistry
·
2023
·
IF 2.6
Xiaoyu Yang
Simultaneous enantioseparation of three commonly used chiral antifungal pesticides (diniconazole, hexaconazole, and imazalil) was first studied based on micellar electrokinetic chromatography (MEKC) with hydroxypropyl-γ-CD (HP-γ-CD) as chiral selector. In this study, the importance of experimental parameters such as chiral selector type and concentration, sodium dodecyl sulfate (SDS) concentration, the ratio of methanol, and separation voltage in optimizing were investigated. The simultaneous enantioseparation of diniconazole, hexaconazole, and imazalil was successfully achieved in 30 mM borate buffer (pH 9.0) containing 10 mM HP-γ-CD and 20 mM SDS with methanol (8%) added as organic modifiers. The resolution of diniconazole, hexaconazole, and imazalil was 15.2, 2.12, and 2.78, respectively, and the peak efficiency (N) was over 566,825 plates/m. This study provides an alternative way to systematically separate chiral antifungal pesticides with high efficiency.
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JOURNAL OF BIOTECHNOLOGY
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2021
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IF 3.307
Jingbai Wen,Jie Bao
Fermentative production of γ-aminobutyric acid by the glutamate overproducing Corynebacterium glutamicum from cheap sugar feedstock is generally regarded as one of the most promising methods to reduce the production cost. However, the intracellularly expressed glutamate decarboxylase in C. glutamicum often showed feeble catalysis activity to convert glutamate into γ-aminobutyric acid. Here we tried to secretory express glutamate decarboxylase to achieve efficient extracellular decarboxylation of glutamate, thus improving the γ-aminobutyric acid production by C. glutamicum . We first tested glutamate decarboxylases from different sources, and the mutated glutamate decarboxylase GadBmut from E. coli with better catalytic performance was selected. Then, a signal peptide of the SEC translocation pathway directed the successful secretion of glutamate decarboxylase in C. glutamicum . The extracellular catalysis by secreted glutamate decarboxylase increased the γ-aminobutyric acid generation by three-fold, compared with intracellular catalysis. Enhancing glutamate decarboxylase expression and decreasing γ-aminobutyric acid degradation further increased γ-aminobutyric acid production by 39 %. The fed-batch fermentation of the engineered C. glutamicum strain reached the record high titer (77.6 ± 0.0 g /L), overall yield (0.44 ± 0.00 g/g glucose), and productivity (1.21 ± 0.00 g/L/h). This study demonstrated a unique design of extracellular catalysis for efficient γ-aminobutyric acid production by C. glutamicum .
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CATALYSIS TODAY
·
2020
·
IF 5.825
Juan Liu,Wen-Ying Li,Jie Feng,Xiang Gao
The improvement of the sulfur tolerance over Pt catalyst is critical for the hydrotreatment of crude oil. Fe was co‒impregnation with Pt on γ-Al 2 O 3 at different calcination temperature. Results revealed that adding Fe significantly facilitated the reduction of Pt oxides for the catalyst calcined at 400 °C. The morphological analysis and CO chemisorption showed Fe improved the dispersion of Pt nanoparticles. The surface chemical state analysis implied the co‒existence of the electron‒deficient Pt and metallic Fe. However, the increase of calcination temperature caused a decreased reducibility of Pt oxides due to strong metal support interaction. A higher dibenzothiophene hydrodesulfurization conversion of 97.7 % with a dominant biphenyl selectivity of 96.7 % were acquired for the catalysts incorporated with Fe. The density functional theory calculations confirmed the alloyed Fe led to the formation of electron‒deficient Pt atoms, and the higher affinity to sulfur made Fe be a favorable additive for noble metal catalyst in the hydrodesulfurization.
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Catalysts
·
2020
·Vol. 10
·期 9
·1096
·
IF 3.52
Ligang Luo,Xiao Han,Qin Zeng
A series of Ni-Fe/SBA-15 catalysts was prepared and tested for the catalytic hydrogenation of levulinic acid to γ-valerolactone, adopting methanol as the only hydrogen donor, and investigating the synergism between Fe and Ni, both supported on SBA-15, towards this reaction. The characterization of the synthesized catalysts was carried out by XRD (X-ray powder diffraction), TEM (transmission electron microscopy), H2-TPD (hydrogen temperature-programmed desorption), XPS (X-ray photoelectron spectroscopy), and in situ FT-IR (Fourier transform–infrared spectroscopy) techniques. H2-TPD and XPS results have shown that electron transfer occurs from Fe to Ni, which is helpful both for the activation of the C=O bond and for the dissociative activation of H2molecules, also in agreement with the results of the in situ FT-IR spectroscopy. The effect of temperature and reaction time on γ-valerolactone production was also investigated, identifying the best reaction conditions at 200 °C and 180 min, allowing for the complete conversion of levulinic acid and the complete selectivity to γ-valerolactone. Moreover, methanol was identified as an efficient hydrogen donor, if used in combination with the Ni-Fe/SBA-15 catalyst. The obtained results are promising, especially if compared with those obtained with the traditional and more expensive molecular hydrogen and noble-based catalysts.Keywords:biomass ester derivatives;solvothermal processing;levulinic acid;γ-valerolactone;Ni-Fe bimetallic catalysts
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