Food Frontiers
·
2025
·
IF 6.9
Sibo Zhao,Jielin Jiang,Yan Liu,Mianhong Xu,Rui Yang,Zhi Yang,Jilin Xie,Zhanggui Ding,Liyong Luo,Liang Zeng
Excessive alcohol consumption in contemporary society induces alcoholic liver disease (ALD). Previous laboratory studies demonstrated hepatoprotective and gut microbiota–modulating effects of ripe Pu-erh tea. To identify the key bioactive components responsible for these effects and to support the development of functional beverages, we investigated the preventive effects of various membrane-separated Pu-erh tea extracts on a chronic ALD mouse model. The extracts included an 800-Da nanofiltration fraction, a fraction isolated via a 50-nm ceramic membrane, the retentate from the 50-nm ceramic membrane filtration, and unfiltered Pu-erh tea. The results revealed that the fraction isolated via a 50-nm ceramic membrane (T4) significantly improved alcohol-induced intestinal barrier dysfunction, reduced lipopolysaccharide (LPS) release, and suppressed the release of proinflammatory cytokines, including tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β). Furthermore, T4 attenuated hepatic lipid accumulation, oxidative stress, and inflammatory responses by modulating the Nrf2/NQO1 antioxidant pathway and inhibiting toll-like receptor 4 (TLR4)/MyD88-mediated proinflammatory signaling. Notably, T4 restored microbial homeostasis by increasing the relative abundance of beneficial bacteria, such as Dubosiella , Muribaculum , and Lactobacillus , and significantly regulated tryptophan metabolism and its related metabolite, indole-3-acetic acid (IAA). Overall, the membrane separation technology enriched T4 with polyphenols and flavonoids, which further regulated tryptophan metabolism by regulating liver oxidative stress and promoting probiotic colonization and ultimately alleviates ALD. The membrane-fractionated Pu-erh tea, particularly T4, represents a promising functional beverage to combat alcohol-induced metabolic disorders.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2025
·
IF 4.6
Juanli Du,Shuang Feng,Wenying Wu,Xu Jing,Hao Wu,Kasim Sakran Abass,Xiaowen Wang,Jianhai Zhang
Sulfonamides (SAs) are widely used, and their residues pose a serious threat to food safety and human health. Herein, we developed a green, accurate, and sensitive method for detecting SAs residues in animal-derived food using a modified QuEChERS method combined with enzyme inhibition–based colorimetry. Magnetic COF (TpPa-Cl)@Fe 3 O 4 was simple to synthesise, chemically stable and reusable. When used as an adsorbent in modified QuEChERS, it simplifies the purification process and has a high purification capacity. An environmentally friendly natural deep eutectic solvent synthesized using propylene glycol and betaine can serve as a green substitute for traditional organic extractants. SAs were detected by inhibiting the colorimetric reaction between carbonic anhydrase and p -nitrophenyl acetate, and were quantitatively analyzed by digital image colorimetry (DIC) of smartphone. Under optimal conditions, the limits of detection and quantification were 0.53–0.86 µg·kg −1 and 1.52–1.95 µg·kg −1 , respectively. The recoveries of SAs were in the range of 93.60%–101.60%, and the relative standard deviation was < 4.9%. Based on the combined results, our developed method has good applicability in the analysis of SAs residues in food.
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
·
2025
·
IF 4.6
Rui Wang,Yanchun Yang,Guonan Cui,Lulu Bai,Zhihui Gong,Chengjun Zhu
CuSb(S, Se) 2 (CASSe) is known to have great potential for copper-based low-cost thin-film solar cells due to its excellent stability, earth-abundant raw materials, and suitability for the low-temperature preparation process. In this work, CASSe thin-film solar cells were prepared using the green n-butylammonium butyrate ionic solution-based method for the first time. The phase purity, crystallinity , morphology, and electrical properties of films prepared at different conditions (sintering and selenization conditions) were studied. With the help of the XRD , Raman spectra , SEM, and c-AFM measurements, the optimal preparation of CASSe thin film is confirmed at 230 °C for 3 min (sintering condition) and 390 °C for 20 min (selenization condition). Using glass/Mo/CuSb(S, Se) 2 /CdS/i-ZnO/ITO/Al as the structure of the device, the corresponding thin film solar cell can be fabricated, which presents a photoelectric conversion efficiency (PCE) of 0.14 %. Although the performance of the device is poor, our conclusions are meaningful in the development of CASSe material, supplementing the blank of preparing CASSe thin film solar cells by the green solution-based method.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Functional Foods
·
2025
·
IF 4
Zhenhua Yin,Hao Zhang,Juanjuan Zhang,Guangyu Hong,Xia Zhang,Qingfeng Guo,Wei Zhang,Li Wang,Lin Chen
Pleurotus placentodes , a nutritionally rich mushroom species within the Pleurotus spp. genus, contains rich polysaccharides. As its primary bioactive component, it has been rarely reported. This study provided the first report on in vitro digestion and fermentation properties of polysaccharide PPp-W through simulated digestion and anaerobic fermentation. The results showed that during simulated digestion, PPp-W resisted enzymatic degradation, as shown by its stable molecular weight and absence of free monosaccharide release. However, PPp-W was degraded and utilized by intestinal microorganisms, leading to the production of short-chain fatty acids (SCFAs), particularly acetic acid (increased 2.61 times) and propionic acid (increased 19.79 times), accompanied by a marked pH reduction in fecal culture medium. PPp-W administration significantly regulated the composition of intestinal flora by enhancing the relative abundance of beneficial bacteria ( Bacteroides , Parabacteroides , and Lactobacillus ) while suppressing harmful bacteria ( Escherichia - Shigella and Enterococcus ). These findings indicated that PPp-W exhibited significant prebiotic potential and represented a promising candidate for functional food applications targeting gut health modulation.
✓ 已验证
产品关联
DOI
高影响因子
Food Bioscience
·
2025
·
IF 5.9
Pengfei Ren,Hui Qi,Biqian Wei,Wanting Qin,Meng Liu
The gut microbiome's composition and function undergo significant remodeling with age, contributing to declining health. While the marine carotenoid astaxanthin (AST) is known to beneficially modulate the gut microbiota, its effects have primarily been studied in young organisms. Whether AST exerts age-divergent effects on the gut ecosystem remains unexplored. We employed an in vitro colonic fermentation model inoculated with fecal samples from healthy young (23–25 years) and elderly (70–75 years) cohorts to investigate the age-specific impact of AST on microbial community structure, ecological networks, and metabolic output. Our findings reveal that AST orchestrates fundamentally distinct, age-adapted ecological strategies. In young microbiomes, AST enhanced microbial diversity and fostered a highly interconnected, cooperative network, concurrently increasing the acetate/propionate ratio and favoring the production of neuroactive metabolites like serotonin. In stark contrast, in elderly microbiomes, AST did not broadly increase diversity but instead induced a targeted restructuring: enriching beneficial taxa, depleting potential pathobionts, and promoting ecological niche specialization. Most notably, AST preferentially and profoundly amplified butyrate synthesis and redirected tryptophan metabolism towards neuroprotective and antioxidant intermediates, such as 3-Hydroxyanthranilic Acid and Niacin, specifically in the aged gut. This study demonstrates that astaxanthin acts as an age-responsive dietary modulator of the gut microbiome. Its ability to tailor its effects—promoting microbial integration in youth while driving functional specialization and restoring key health-related metabolites in old age—highlights its significant potential for developing precision nutrition strategies aimed at promoting healthy aging.
✓ 已验证
产品关联
DOI
高影响因子
Laser & Photonics Reviews
·
2025
·
IF 10
Mengxin Liu,Jiejun Pan,Xinan Shi,Bingsuo Zou,Daocheng Pan
Rare-earth doped metal oxide nanocrystals with high visible luminescence have been widely used in lighting and display applications owing to their low toxicity, and excellent thermal and chemical stability. However, the room-temperature preparation of near-infrared (NIR) luminescent rare-earth doped metal oxide nanocrystals remains a challenge. Herein, sub-4 nm Yb 3+ /Nd 3+ -doped CaMoO 4 nanoparticles are prepared by a facile room-temperature ligand-assisted coprecipitation method, which can be completed within 1 min under ambient conditions. Short-chain butyric acid and butylamine as binary ligands play a crucial role in the synthesis of NIR luminescent nanoparticles. The as-prepared nanocrystals can be well dispersed in organic solvents such as chloroform since they are capped with butyric acid and butylamine. The energy transfers from MoO 4 2 − ${\rm MoO}^{2-}_{4}$ ions to Yb 3+ and Nd 3+ ions are systematically investigated in CaMoO 4 :Yb 3+ and CaMoO 4 :Nd 3+ nanoparticles, respectively. More importantly, this ultrafast and room-temperature synthesis strategy is particularly suitable for the large-scale preparation of Yb 3+ /Nd 3+ -doped CaMoO 4 nanoparticles (≈23 g) with NIR emission, which provides new ideas and possibilities for the commercial production of extremely small and NIR-emitting nanophosphors.
✓ 已验证
产品关联
DOI
高影响因子
FOOD HYDROCOLLOIDS
·
2025
·
IF 12.4
Han Qiu,Angxin Song,You Luo
Rosa roxburghii Tratt fruits are rich in polysaccharides. Two novel polysaccharides, RRTP-1 and RRTP-2, were purified and characterized as pectin using HPLC, FTIR, GC-MS, and NMR analysis. RRTP-1 was primarily composed of homogalacturonan (HG), featuring a linear main chain with various branching structures including galactose, glucose, arabinose, and mannose residues. RRTP-2 was also a highly branched HG with significant contributions from galactose, rhamnose and arabinose. Compared to RRTP-2 (262.35 kDa, DE 22.03 %), RRTP-1 exhibited a lower molecular weight (179.05 kDa) and a higher degree of esterification (DE, 41.10 %). Both of them were efficiently utilized by gut microbes to produce butyric acid and lower pH. Their structural differences led to distinct gut microbiota composition. RRTP-1 selectively enriched Phocaeicola , Faecalibacterium , and Bifidobacterium , whereas RRTP-2 selectively enriched Limosilactobacillus , Lachnospira , and Coprococcus . Despite structure differences in RRTP-1 and RRTP-2, the keystone microbes and enzymes involved in their degradation exhibited similarities. Bacteroides and Megamonas emerged as dominant contributors. Glycoside hydrolases and carbohydrate esterases were identified as the primary enzymes facilitating their breakdown. These findings suggest that the fine structure of pectin exerts a selective effect on fermenting consortia. Furthermore, both RRTP-1 and RRTP-2 show promise as effective prebiotics.
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL PHYSICS
·
2024
·
IF 2
Xinyuan Zhang,Xinyao Tang,Zhenhai Zhong,Xinyi Ge,Qingguo Zhang
The hydroxylammonium ionic liquids (ILs) falling within the category of protic ionic liquids (PILs) have garnered attention from researchers, owing to their outstanding solubility properties. A one-step method was employed to synthesize a series of ethanolamine ILs. The thermodynamic properties of the ILs, including surface tension, density, and electrical conductivity, were measured across varying temperatures. Essential parameters such as thermal expansion coefficient, molecular volume, surface entropy, and surface energy were estimated using empirical equations. In order to elucidate the intermolecular interactions within the ethanolamine carboxylate ILs, the sigma profiles of ILs were determined using COSMO-RS. It was observed that the ethanolamine cation has a strong potential as a H-bond donor, while the carboxylate anion demonstrates significant capability as a hydrogen bond acceptor. By DFT calculations, it was observed that the N H in the ethanolamine cation can form H-bonds with the oxygen atom in the carboxylate anion.
✓ 已验证
产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2024
·
IF 10.7
Jingjing Dong,Yanli Wang,Ying Chen,Qin Wang,Bo Zhang,Xiaoxiao Li,Zhengyu Jin,Yuxiang Bai
The recently characterized Limosilactobacillus reuteri N1 GtfB (LrN1 GtfB) from glycoside hydrolase family 70 is a novel 4,6-α-glucanotransferase acting on starch/maltooligosaccharides with high enzyme activity and soluble protein yield (in heterogenous system). In this study, the influence of the treatment by LrN1 GtfB on the fine structure and functional characteristics of three maize starches were furtherly investigated and elucidated. Due to the treatment of LrN1 GtfB, the starch molecules were transformed into reuterans containing linear and branched (α1 → 6) linkages with notably smaller molecular weight and shorter chain length. Moreover, the (α1 → 6) linkage ratios in the GtfB-modified high-amylose maize starch (GHMS)/normal maize starch (GNMS)/waxy maize starch (GWMS) increased by 18.3 %/12.6 %/9.0 % as compared to their corresponding controls. In vitro digestibility experiment revealed that the resistant starch content of GHMS, GNMS and GWMS increased by 16 %, 18 % and 25 % as compared to the starch substrates. Furthermore, the butyric acid yielded from GHMS, GNMS and GWMS in the in vitro fermentation experiments were 1.4, 1.5 and 1.4 times higher than those of commercial galactose oligosaccharides . These results indicated that the highly-branched short-clustered reuteran synthesized by LrN1 GtfB might serve as novel potential prebiotics , and provide insights for the synthesis of promising prebiotic dietary fiber from starch.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Food Bioscience
·
2024
·
IF 4.8
Jingyi Wang,Shumin He,Sihong Tao,Shuzhen Ma,Yufan Luo,Muci Wu,Mengzhou Zhou
This study explores the effect of ultrasound-assisted cellulase (UE) processing on the structure, functional performance, and prebiotic properties of guava insoluble dietary fiber (RIDF). As the ultrasound exposure time increased (0–40 min), the particle size (from 126.3 μm to 38.7 μm) and crystallinity (from 30.72% to 14.42%) of RIDF significantly decreased, while its soluble carbohydrate content (from 1.40% to 6.17%) and water solubility (from 8.6% to 16.4%) notably increased. These crucial changes suggested the degradation and disorganization of RIDF. Meanwhile, UE-RIDF (modified RIDF) demonstrated a honeycomb network microstructure with a larger surface area, indicating distinct structural and morphological properties compared to RIDF. Consequently, UE-RIDF showed stronger retention/adsorption capacity and improved in vitro prebiotic activity. Interestingly, UE treatment increased RIDF fermentability, leading to additional shifts in its modulation of human fecal microbiota, including a higher abundance of Proteobacteria and Phascolarctobacterium . Furthermore, compared to pure cow/goat yogurt, yogurt fermented with UE-RIDF displayed a lower pH, better stability, and improved texture and rheological properties during a 21-day refrigeration period. These findings highlight the potential application of RIDF as a novel prebiotic active ingredient in fermented foods for the first time, underscoring the critical role of UE treatment in enhancing its performance.
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Energy Materials
·
2024
·
IF 5.4
Fuyan Chen,Bowen Liu,Wei Shao,Jiaxin Gao,Chenxi Zhao,Dongdong Shen,Daocheng Pan,Xinan Shi
Compared with the traditional Mo back electrode of Cu2ZnSn(S,Se)4 (CZTSSe) solar cells, the transparent and conductive electrode of fluorine-doped tin oxide (FTO) has the advantages of low lattice mismatch with the CZTSSe absorber, earth-abundant composition, transparency, and advanced applications in building integrated photovoltaics. Hence, the research of bifacial FTO/CZTSSe thin film solar cells has attracted more and more attention. However, the poor interface contact between n-type FTO/p-type CZTSSe prevents the improvement of power conversion efficiency (PCE) of CZTSSe thin film solar cells deposited on the FTO substrate. Therefore, back contact interface modification is an effective strategy to promote the performance of the FTO/CZTSSe solar cells. Here, we choose the solution-processed MoO3 as the interface layer to modify the interface of FTO/(Cu,Ag)2ZnSn(S,Se)4 (CAZTSSe), and systematically investigate the effects of the thickness of MoO3 interface layer on the performance of FTO/MoO3/CAZTSSe solar cells. It is found that the optimal thickness of the solution-deposited MoO3 interface layer is 30 nm. As a result, kesterite solar cells on the FTO substrate achieve a front-side PCE of 9.49 % and a rear-side PCE of 1.04%.
✓ 已验证
产品关联
DOI
高影响因子
Solar RRL
·
2024
·
IF 6
Chenxi Zhao,Bowen Liu,Fuyan Chen,Jiaxin Gao,Xinan Shi,Daocheng Pan
Cu(In, Ga)(S, Se) 2 (CIGSSe) solar cell is one of the most promising thin-film solar cells with a record power conversion efficiency (PCE) of 23.6%. Conventional CIGSSe thin-film solar cells are usually fabricated on Mo-coated soda-lime glass substrate, thereby, the sunlight on the rear side cannot be utilized by the monofacial CIGSSe solar cells owing to the opacity of the Mo electrode. CIGSSe solar cells fabricated on transparent conductive oxide (TCO) electrode enable to fabricate bifacial solar cells, which can generate power on both sides of solar cells, so that bifacial solar cells have a high potential application in building-integrated photovoltaics. However, the PCEs of CIGSSe solar cells fabricated on TCO substrates are significantly lower than those of ones on Mo substrates. In this article, bifacial CIGSSe solar cells on fluorine-doped tin oxide (FTO) substrate are fabricated by using an ionic liquid-assisted solution approach and utilizing a MoO 3 thin film as an interface layer between FTO and CIGSSe absorber layer, yielding a front-side PCE of 9.73% and a back-side PCE of 1.77%.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）