Analytical Methods
·
2024
·
IF 2.7
Yanhong Chen,Li Lv,Xuanjiao Mao,Jun Chai,Jayne Wu,Yicheng Zhou,Jian Zhang,Haochen Qi
A flexible electrochemical sensor with high sensitivity and specificity is developed using gold nanoparticles (AuNPs) and a reduced graphene oxide/molybdenum disulfide (rGo–MoS2) composite modified screen printed carbon electrode (SPCE), with L-cysteine (L-Cys) as a probe for Cu2+ target recognition. Owing to the AuNPs/rGo–MoS2, the electron transference ability is improved by increasing the specific surface area of the working electrode, and a high sensitivity is achieved. Meanwhile, the bidentate chelation of L-Cys to Cu2+ contributes to a good selectivity. Using differential pulse voltammetry (DPV) for spiked standard Cu2+, the test results show a dynamic range from 0.1 μM to 100 μM, a detection limit of 0.020 μM, and a high sensitivity of 1.190 μA μM−1. Furthermore, detection in both environmental water and human plasma samples demonstrates a wide applicability of this sensor in various matrices, and an excellent feasibility for environmental and clinical applications.
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PubMed
高影响因子
JOURNAL OF MOLECULAR STRUCTURE
·
2024
·
IF 4
Hao Hu,Lei Xue,Yelin Yao,Linlong Deng,Haibin Wang
A novel fluorescent probe, WH , was successfully designed and synthesized. WH demonstrated continuous detection capabilities for Cu 2+ and EDTA in the HEPES system. Specifically, the introduction of copper ions resulted in fluorescence quenching, while the addition of EDTA led to the recovery of fluorescence. The detection limits of WH for Cu 2+ and EDTA were calculated to be 29.66 and 172.13 nmol· L −1 , respectively. Moreover, WH exhibited AIE property in THF/H 2 O system. According to the Job's plot, 1 H NMR titration and mass spectrometry, WH could form a complex with Cu 2+ in a 1:1 ratio, and the combinding constant was 8.2 × 10 3 L mol −1 . WH exhibited outstanding selectivity, high sensitivity, large Stokes shift and strong anti-interference ability. Furthermore, WH had been successfully applied in the detection of Cu 2+ in beer and red wine, showcasing its promising potential for practical application.
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JOURNAL OF MOLECULAR STRUCTURE
·
2022
·
IF 3.841
Xiaoling Niu,Hong Zhang,Xiaojing Wu,Shengbo Zhu,Yongliang Liu,Min Tian
Developing highly selective and sensitive sensor for Cu 2+ ions is very important in the fields of chemical, biological and environmental. Herein, a novel Cu 2+ ions sensor based on tetraphenylethylene (TPE) derivative with aggregation-induced emission (AIE) property was designed and synthesized. It was prepared by introducing four Cu 2+ ion chelating centers onto TPE core, which exhibited a sensitive fluorescent “turn-off” behaviour and highly selective responses to Cu 2+ ions in the present of various interferential cations. It also showed a visible colour change from bright yellow to colourless at the addition moment of Cu 2+ ions. The responses mechanism was revealed by 1 H NMR spectrum, dynamic light scattering (DLS) analysis and density functional theory (DFT) calculation. The results showed that the coordination of the sensor's N, O atoms with Cu 2+ ions induced the TPE-Schiff base's structure planarization, and formed a very tight Cu 2+ complex in nano-size aggregation state, which led to the fluorescent emission “ turn-off ”. This study provides a valuable approach to design and prepare AIE-active fluorescent sensor for the detection of Cu 2+ ions.
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Han Yang,Renqiang Chen,Linjun Dai,Boquan Ren,Feng Yang,Yan-Jun Xu,Qing Li
The purpose of this study was to develop a novel reaction-based fluorescent sensor for the detection of Cu 2+ and glutathione in real wine samples. The sensor, tris-(2-pyridyl)-methylamine rhodol derivative, was synthesized and validated for the tandem and selective detection of both Cu 2+ and glutathione. The sensor exhibited a strong linear correlation between fluorescence intensity and Cu 2+ concentration ranging from 100 to 900 nM, while the in situ generated Cu 2+ ensemble selectively detected glutathione with a robust linear response from 3 to 30 μM. The detection limits for Cu 2+ and glutathione were as low as 28 nM and 0.60 μM, respectively. Additionally, the sensor enabled quantitative detection of Cu 2+ and glutathione in real wine samples. This work provides the first reaction-based fluorescence sensor with an “on-off-on” fluorescence response for the tandem detection of Cu 2+ and glutathione in wine, offering potential applications in food and beverage quality control.
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PubMed
高影响因子
Micro & Nano Letters
·
2020
·Vol. 15
·期 8
·535-539
·
IF 0.975
Hongguang Zhang,Meng Wang,Feng Xu
Developing cheap photocatalysts with highly visible-light activity is greatly desired for environmental pollution treatment. In this work, the authors designed and synthesised Cu 2+ -doped TiO 2 (Cu-TiO 2 ) hollow spheres with enhanced photocatalytic activity and antimicrobial activity using a simple hydrothermal process. The X-ray powder diffraction (XRD) results revealed that Cu-TiO 2 hollow spheres were anatase crystal phase. The Cu 2+ -doped into TiO 2 can be confirmed by XRD, Raman spectra, and UV–Vis spectrum. The photocatalytic activity of Cu-TiO 2 samples was evaluated by the degradation of methyl orange. Comparing to the undoped TiO 2 , 6% Cu-TiO 2 sample exhibited remarkably high photocatalytic towards methyl orange under simulated sunlight irradiation, which was attributed to the fact that copper ion doping produced numerous oxygen vacancies (V O ) in the material. In addition, it also showed improved antibacterial properties against both Gram-positive Staphylococcus aureus ( S.aureus ) and Gram-negative Escherichia coli ( E.coli ) bacteria. These results establish that Cu 2+ doping can obviously improve the photocatalytic performance of TiO 2 under simulated sunlight.
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高影响因子
TOXICON
·
2019
·
IF 2.276
Dong Ao,Zhen Lei,Mawuli Dzakpasu,Rong Chen
Cu 2+ and Zn 2+ , two ubiquitous metals in water environments, can widely trigger algae blooms at favourable environmental conditions. This paper elucidates the roles of Cu 2+ and Zn 2+ in the proliferation of Microcystis aeruginosa ( M. aeruginosa ) and synthesis of Microcystins (MCs). Findings indicate significant influences of increasing Cu 2+ and Zn 2+ concentrations on cell proliferation at limited available phosphorus concentrations of less than 0.1 mg/L. By contrast, Cu 2+ and Zn 2+ notably affected MCs production at all the inoculated phosphorus concentrations. The critical concentrations of 1 μg/L and 5 μg/L for Cu 2+ and Zn 2+ , respectively, are determined to trigger rapid cell proliferation and MCs production. Furthermore, the impacts of Cu 2+ and Zn 2+ on nitrogen absorption and, subsequently, on amino acids (AAs) formation in cells, is likely key in MCs synthesis. The two AAs Alanine (Ala) and glutamic acid (Glu) demonstrate the most notable variations with the concentrations of Cu 2+ & Zn 2+ .
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高影响因子
Methods and Applications in Fluorescence
·
2022
·Vol. 10
·期 3
·035004
·
IF 3.849
Linli Xiong,Yong Zheng,Haibo Wang,Jiangyang Yan,Xuguang Huang,Hongyun Meng,Chunhua Tan
A novel fluorescence sensor for successive detection of Cu2+ and Fe3+ based on anti-B18H22 derivative which possesses 5-hydroxyisoquinoline as an ionophore was synthesized via a one-pot and its structure and photophysical properties were characterized by NMR, HRMS, FTIR, UV–vis, PL and theoretical calculation. The fluorophore displays two emission peaks at 460 nm and 670 nm in THF solution coming from the emission of the locally excited state and intramolecular charge transfer fluorescence, respectively. The complex exhibited obvious aggregation-induced emission enhancement (AIEE) characteristics in THF/H2O solution by increasing the aqueous concentration from 70% to 95%. The AIEE molecules showed a high selectivity towards Cu2+ over other metal ions by forming a 2:1 metal-to-ligand complex in THF/H2O (fw = 20%) solution, the fluorescence intensity increased as a linear function of the Cu2+ concentration at 460 nm due to the inhibition of PET effect. The fluorescent emission was quenched linearly by the addition of Fe3+, which provides a method for successive determination of Cu2+ and Fe3+ based on 'off-on-off' fluorescence of the fluorescent. The detection limit of Cu2+ and Fe3+ was 5.7 × 10−6 M and 7.2 × 10−5 M respectively. Morever, a rapid identification of Cu2+ in the aqueous solution by naked eyes can be realized. In addition, the molecules were pH-sensitive, the fluorescence quenching can be observed in strongly alkaline environment. The method has been applied to the determination of copper ions in water samples with satisfactory results.
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高影响因子
CRYSTENGCOMM
·
2018
·Vol. 20
·期 14
·1945-1953
·
IF 3.304
Kaimin Du,Xia Xu,Shuang Yao,Pengpeng Lei,Lile Dong,Manli Zhang,Jing Feng,Hongjie Zhang
Hexagonal phase (β-) NaYF4:Yb/Er upconversion (UC) microrods doped with Cu2+ ions were prepared via a facile solvothermal method. Simultaneous phase and shape control of NaYF4:Yb/Er crystals with enhanced upconversion luminescence (UCL) was successfully realized by codoping with Cu2+ ions. With an increasing Cu2+ ion concentration in the NaYF4:Yb/Er system, the crystal structure changed from a mixture of α- and β-phases to the pure β-phase and was converted into highly uniform microrods. As for the Cu2+ ion doped β-NaYF4:Yb/Er upconversion microrods, the maximum emission occurs with the sample added with 60 mol% Cu2+ ions and the UCL intensities of the green and red emissions were enhanced 37 and 25 times, respectively. Meanwhile, the possible mechanisms for the enhanced UCL of NaYF4:Yb/Er crystals were also discussed in detail. Moreover, the temperature dependent UCL properties of 60 mol% Cu2+ ion doped β-NaYF4:Yb/Er were studied under 980 nm excitation, which were temperature-sensitive over a wide temperature range from 123 K to 423 K. The change in UCL intensity influenced by temperature was discussed in detail.
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CERAMICS INTERNATIONAL
·
2026
·
IF 6
Keqin Zhou,Weifeng Song,Zuoyi Yang,Guangwen Zheng,Yantong Gao,Chuanying Tu,Jingfeng Peng,Junming Bian,Qian Yin
Owing to their excellent fluorescence and other advantageous properties, quantum dots (QDs) are promising candidates for environmental monitoring. Although we synthesized previously CdS QDs using extracellular polymeric substances (EPS) produced by sulfate-reducing bacteria ( Desulfovibrio desulfuricans subsp. desulfuricans ) as biological template, systematic optimization of the synthesis conditions and in-depth investigation of their fluorescence properties remain limited. In the present study, based on an EPS-templated strategy, key synthesis parameters (such as pH, EPS concentration, and precursor ratios) were systematically optimized, enabling the successful extracellular preparation of bright cyan-green fluorescent CdS QDs with an emission maximum at 520 nm and a quantum yield of 11%. Comprehensive characterization confirmed their size (∼4.8 nm), good crystallinity (lattice spacing of 0.209 nm for the (220) plane), and successful formation of Cd-S bonds. FT-IR spectroscopy further indicated that the surface of the QDs was rich in functional groups such as carboxyl, hydroxyl, amino, and thiol groups, which significantly enhanced the colloidal stability of the CdS QDs in solution. The probe exhibited a response time of 5 min, high sensitivity (detection limit of 48 nM), a wide linear range (0–60 μM, R 2 = 0.992), and excellent selectivity for Cu 2+ . Time-resolved fluorescence studies suggested a dynamic quenching mechanism. Satisfactory recovery rates (99.52-110.11%) in real water samples (river and tap water) validated its practical applicability. This work presents a novel EPS-templated biosynthesis route for CdS QDs and establishes an efficient sensing platform, offering a promising strategy for rapid, low-cost heavy metal detection in environmental waters.
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高影响因子
Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 2
·121881
·
IF 7.5
Qun Liu,Jiexiong Zhong,Huaiyu Wang,Shiqi Song,Xiaohui Xu,Wei Yang,Min Lu
The thorough removal of Cu 2+ from water poses a formidable challenge in environmental remediation. To overcome the performance limitations of traditional adsorbents that rely on physical pores or single functional groups. This study successfully constructs a hierarchical mesoporous composite, denoted as Cys-PDA@CoNi-LDH (where Cys, PDA, and LDH refer to L -cysteine, polydopamine, and layered double hydroxide, respectively). It is synthesized by grafting Cys onto a PDA framework via Michael addition, followed by in situ growth of CoNi-LDH nanosheets. The composite exhibits a high Cu 2+ adsorption capacity of 295.3 mg·g −1 and a removal efficiency of 92.2 % under optimal conditions (318 K, pH=6), with strong resistance to ionic interference. The synergistic mechanism involves specific -SH coordination, LDH ion exchange, surface complexation, and mesoporous confinement. Efficient desorption (86 % recovery) is achieved using 0.1 mol·L −1 HCl, and over 75 % of the initial capacity is retained after five cycles. Fixed-bed column experiments confirm its practical potential, with breakthrough curves well-fitted by Thomas and Yoon-Nelson models (adjusted R 2 = 0.986–0.999). Notably, it achieves a treatment capacity of 1.7 L·g −1 for low-concentration Cu 2+ (5 mg·L −1 ). This work provides a promising strategy for designing selective and renewable adsorbents for water purification.
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CEMENT AND CONCRETE RESEARCH
·
2026
·
IF 14
Zedong Zhou,Hangxi Liu,Juanlong Li,Yiru Yan,George Dan Miron,Barbara Lothenbach,Biwan Xu,Ming Fang,Xiaoli Tan,Bin Ma
Calcium silicate hydrate (C-S-H), the principal binding phase in Portland cement, plays a critical role in the immobilization of heavy metals, yet a quantitative and mechanistic understanding of Cu 2+ uptake by C-S-H remains incomplete. This study investigates the immobilization behavior of Cu 2+ by C-S-H with systematically controlled Ca/Si ratios (0.6–1.6) and develops a thermodynamically consistent sublattice solid-solution model. The C-S-Hs were synthesized under sorption equilibrium conditions and characterized to determine their structural evolution with Ca/Si ratio. Cu 2+ sorption was subsequently examined on pre-synthesized C-S-Hs, combined with spectroscopic analyses to elucidate Cu coordination environments. The results show that Cu 2+ is immobilized predominantly through structural incorporation at low Cu 2+ loadings rather than hydroxide precipitation. With increasing Cu 2+ concentration, Cu 2+ progressively intercalates into the interlayers of C-S-H, partially replacing interlayer Ca 2+ and forming Si-O-Cu linkages associated with Q 2 silicate sites. The Ca/Si ratio strongly controls both uptake capacity and binding mechanism. High Ca/Si ratios promote silicate-chain polymerization through conversion of Q 1 to Q 2 units, whereas extremely low Ca/Si ratios induce redistribution between Q 2 and Q b 2 species. At intermediate Ca/Si ratios, Cu 2+ is mainly stabilized as hydroxyl-associated species. Once the sorption capacity is exceeded, excess Cu 2+ transforms into CuO under alkaline conditions. Based on these observations, a CASH+Cu thermodynamic model incorporating five Cu-bearing endmembers was developed and calibrated using both aqueous and solid-phase data. The model quantitatively reproduces Cu uptake, solution chemistry, and phase assemblages, providing a predictive framework for Cu 2+ retention in cementitious systems.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 8.3
Lu-feng Wang,Ya-nan Zhang,Mao-qing Chen,Yingxuan Liu,Yong Zhao
Given the dual role of copper ions (Cu 2+ ) as essential micronutrients and harmful pollutants, the demand for developing sensitive and selective sensors capable of trace-level Cu 2+ monitoring in water bodies is urgently needed. In this paper, an ultra-sensitive surface plasmon resonance (SPR) optical fiber Cu 2+ sensor is proposed, which consists of a multimode fiber (MMF) and a 1 cm single-hole dual-core micro-structured fiber (MOF). Femtosecond laser micromachining is employed to fabricate microfluidic channel within the MOF, followed by polydimethylsiloxane (PDMS) infusion to induce an effective refractive index (RI) difference between dual cores to construct a Michelson interferometer (MI) for temperature monitoring. Simultaneously, a gold film is deposited on the MOF surface served as the SPR excitation channel, and multilayers Schiff base-functionalized hydrogel composites are immobilized onto the gold film through electrostatic layer-by-layer (LBL) self-assembly. The specific chelation between Cu 2+ with Schiff base ligands triggers hydrogel swelling, thereby inducing significant resonance wavelength shifts in the SPR spectrum. Experimental results demonstrate that the sensitivity of Cu 2+ has increased by 6 times, with the maximum sensitivity reaching −504.96 nm/(mg/L) and the limit of detection (LOD) as low as 11.0149 nM. The MI channel exclusively responds to PDMS variations due to temperature, exhibiting insensitivity to Cu 2+ concentration fluctuations, thereby eliminating the temperature cross-talk in the SPR channel. The proposed method provides a new thought for the integrated design of sensitive and specific sensors, which has great potential in food safety, environment and biology monitoring.
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高影响因子
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