Journal of Physical Chemistry C
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2023
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IF 3.7
Huan-Yu Chen,Xing-Biao Liu,Qi-Xin Guan,Can-Jun Zou,Ping-Ping Fang
The detection of antibiotics has attracted great attention among scientists and health researchers in the past decades. However, it is still difficult to realize the sensitive and selective detection of antibiotics with similar structures. Herein, the antibiotic molecules of oxytetracycline (OTC) can be sensitively and selectively detected by surface-enhanced Raman spectroscopy (SERS) on NH2–UiO-66(Zr)@Au nanoparticles (NPs). The SERS substrate of NH2–UiO-66(Zr)@Au NPs realizes a detection sensitivity of 1 × 10–12 g·L–1 for 4-mercaptobenzoic acid, indicating its high SERS activity. A high detection sensitivity of 10–11 g·L–1 is obtained for OTC on such a SERS substrate. Besides the high sensitivity, NH2–UiO-66(Zr)@Au NPs can also selectively detect OTC from streptomycin sulfate, salicylic acid, and ofloxacin by SERS on NH2–UiO-66(Zr)@Au NPs, with a selective detection limit of 10–10 g·L–1. Furthermore, OTC can be selectively detected in a real sample of river water with a detection limit of 1.0 × 10–10 g·L–1. Therefore, this study provides an effective way to enrich and detect antibiotics in real samples in the environment.
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ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Li Wang,Yi Pan,Zhengwu Wang,Yuanfeng Wang,Xinlin Wei
Organophosphorus pesticides (OPPs) are extensively used in agricultural production, and the contamination caused by their residues has raised significant concerns regarding potential threats to human health. Herein, a novel fluorescence nanoprobe based on an enzyme-mediated silver nanoparticle-modified metal organic framework (AgNPs@PCN-224) was successfully prepared for the rapid detection of OPPs. Initially, AgNPs@PCN-224 were synthesized by reducing silver nitrate (AgNO3) using sodium borohydride (NaBH4) embedded into luminescent PCN-224. This triggered the inner filter effect, leading to fluorescence quenching. Meanwhile, under the catalysis of acetylcholinesterase (AChE) and choline oxidase (CHO), acetylcholine (ATCh) was decomposed to hydrogen peroxide (H2O2), which could destroy AgNPs to form Ag+ released from PCN-224 for fluorescence recovery. Instead, fenitrothion, an OPP, inhibited AChE activity, allowing the quenched fluorescence to be reactivated. Under the current optimum conditions, the fluorescence intensity had a good correlation (Y = −728.5370X + 2178.4248, R2 = 0.9869) over a dynamic range of fenitrothion concentrations from 0.1 to 500 ng/mL, with an LOD of 0.037 ng/mL. In addition, the anti-interference ability and robustness of the proposed sensor was verified for the monitoring of fenitrothion in tea with recoveries of 87.67–103.72% and the relative standard deviations (RSD) < 5.43%, indicating that the system has excellent prospects for OPP determination in practical applications. Furthermore, this work provides a universal platform for screening other enzyme inhibitors to detect OPPs.
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International Journal of Electrochemical Science
·
2023
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IF 1.5
Yong Chang,Fengli Gao,Tong Wu,Qiuzhi Pan,Lin Liu,Qijun Song
Protein kinases play a vital regulatory role in various biological processes. In this work, we developed an electrochemical biosensor for the detection of protein kinases using methylene blue (MB)-functionalized Zr-based metal-organic frameworks (MOFs, UiO-66-NH 2 ) as the signal labels. The results of UV-Vis spectroscopy, X-ray diffraction and N 2 adsorption–desorption experiments confirmed the successful encapsulation of MB into UiO-66-NH 2 . The phosphate groups in phosphorylated peptides were recognized by UiO-66-NH 2 via the robust coordination with Zr-O clusters on the surface of MOFs. The encapsulated MB molecules in UiO-66-NH 2 produced a strong electrochemical signal for highly sensitive detection of protein kinases, which was recorded by square wave voltammetry (SWV). With protein kinase A (PKA) as a model target, the biosensor achieved a detection limit of 0.02 U/mL and a linear range from 0.05 to 20 U/mL. The proposed biosensor was utilized to screen potential inhibitors and determine PKA in serum samples with satisfactory results. This work provided an effective strategy for electrochemical assays of phosphorylation-related biological events in clinical diagnosis.
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Nano Energy
·
2023
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IF 17.6
Xiangcong He,Jinju Zheng,Tao Yang,Deliu Ou,Chris R. Bowen,Songhan Shi,Qiaochu Chen,Hui Fu,Shuangwu Huang,Yumin Ye,Xiaocheng Huang,Wenna Liu,Weiyou Yang
Piezoelectric nanogenerators (PENGs), which operate based on mechanical-to-electrical energy conversion, have been widely explored for exciting applications in modern devices such as wearable electronics , self-powered sensors, and energy harvesters . Herein, we report on high-performance PENGs based on Cs 2 Ag 0.3 Na 0.7 InCl 6 double perovskite (CDP) within a polyvinylidene fluoride (PVDF) matrix, which exhibit enhanced polarity due to rationally designed Zr/Te codoping. As a proof of concept , the resultant PENGs based on Zr/Te codoped CDP@PVDF deliver an excellent piezoelectric output, with a maximum open-circuit voltage and short-circuit current density of 67 V and 18 μA·cm −2 . This level of performance is ∼19 and ∼12 times higher than PVDF-based PENGs with no CDP, and ∼2 and ∼4 times higher than CDP@PVDF-based PENGs without doping or with single Te doping, and ∼1 and ∼2 times higher than CDP@PVDF-based PENGs with single Zr doping, respectively. Moreover, the as-assembled PENGs exhibit impressive potential in wearable energy harvesters, motion sensors, and DC-power devices with robust stability, underscoring their bright future toward practical applications.
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SENSORS AND ACTUATORS B-CHEMICAL
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2023
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IF 8.4
You Lei,Yuting Gao,Yi Xiao,Pengcheng Huang,Fang-Ying Wu
Developing a fluorescence sensor capable of precisely identifying highly toxic nerve agents has become a focus of research, given that they are easily available and can be used by terrorists to threaten the security of the world. In this work, we designed a ratiometric fluorescence sensing platform with Cu 2+ -modified UiO-66-NH 2 (Cu 2+ @UiO-66-NH 2 ) and o-phenenediamine (OPD) as signal indicators and successfully used for the liquid and gas detection of the nerve agent simulant diethyl chlorophosphate (DCP). UiO-66-NH 2 obtained oxidase activity by simple Cu 2+ modification, which catalyzed the oxidation of OPD to give a yellow fluorescent product 2, 3-diaminophenazine (DAP). In this detection system, the fluorescence of UiO-66-NH 2 was greatly enhanced by blocking the ligand metal charge transfer (LMCT) process inside the framework by DCP. At the same time, the amino group of DAP was phosphorylated by DCP, and the attenuation of DAP fluorescence was observed by the static quenching effect. In addition, the Cu 2+ @UiO-66-NH 2 /OPD loaded agarose hydrogel device can be used to detect DCP vapor with naked eyes and showed satisfactory detection result (LOD: 6.65 ppb).
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FOOD CHEMISTRY
·
2023
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IF 8.8
Yijian Zhao,Meiyi Liu,Shuai Zhou,Zhiyu Yan,Jingsheng Tian,Qiaojuan Zhang,Zhiyi Yao
Accurate on-site analysis of tetracycline (TC) is of great research value for ensuring food safety and estimating environmental pollution. Herein, a smartphone-based fluorescent platform for TC detectionhas been developed based on a europium functionalized metal–organic framework (Zr-MOF/Cit-Eu). Based on the inner filter and antenna effect between Zr-MOF/Cit-Eu and TC, the probe exhibited a ratiometric fluorescent response toward TC, resulting in an emission color change from blue to red. Excellent sensing performance was achieved with a detection limit of 3.9 nM, consistent with the linear operation spanning nearly four orders of magnitude. Subsequently, visual test strips based on Zr-MOF/Cit-Eu were prepared, possessing the potential for accurate testing of TC via RGB signals. Finally, the proposed platform was well applied in actual samples with satisfied recoveries (92.27 to 110.22%). This MOF-based on-site fluorescent platform holds great potential on constructing intelligent platform for visual and quantitative detection of organic contaminants.
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International Journal of Electrochemical Science
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2023
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IF 1.5
Ying Wang,Liya Zhang
In recent years, with the misuse and uncontrolled release of antibiotics, the detection of antibiotics has become an important area of research in analytical chemistry. This work utilizes the self-polymerization property of dopamine in alkaline solution to synthesize polydopamine-coated Zr-MOF composites (Zr-MOF-PDA) using zirconium-based metal-organic framework (Zr-MOF) of ligand 4-carboxyphenylporphyrin as the carrier material. The electrochemical sensor for highly sensitive detection of amoxicillin (AMO) was successfully constructed by drop coating this compliant material on the surface of glassy carbon electrode. The AMO was detected by differential pulse voltammetry under the optimized experimental conditions. The linearity range was 0.25~90 μM, and the detection limit was 71 nM. The sensor was successfully used to determine AMO in river water and tap water samples with good recovery. The proposed sensor provides a feasible solution for the sensitive detection of AMO.
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RSC Advances
·
2023
·Vol. 13
·期 16
·11215-11224
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IF 3.9
Haidi Feng,Lu Zhao,Zhiqiang Bai,Zhihui Xin,Chaoyu Wang,Lizhen Liu,Jinping Song,Haifei Zhang,Yunfeng Bai,Feng Feng
Active-targeted nanoplatforms could specifically target tumors compared to normal cells, making them a promising therapeutic agent. The aptamer is a kind of short DNA or RNA sequence that can specifically bind to target molecules, and could be widely used as the active targeting agents of nanoplatforms to achieve active-targeted therapy of tumors. Herein, an aptamer modified nanoplatform DOX@PCN@Apt-M was designed for active-targeted chemo-photodynamic therapy of tumors. Zr-based porphyrinic nanoscale metal organic framework PCN-224 was synthesized through a one-pot reaction, which could produce cytotoxic 1O2 for efficient treatment of tumor cells. To improve the therapeutic effect of the tumor, the anticancer drug doxorubicin (DOX) was loaded into PCN-224 to form DOX@PCN-224 for tumor combination therapy. Active-targeted combination therapy achieved by modifying the MUC1 aptamer (Apt-M) onto DOX@PCN-224 surface can not only further reduce the dosage of therapeutic agents, but also reduce their toxic and side effects on normal tissues. In vitro, experimental results indicated that DOX@PCN@Apt-M exhibited enhanced combined therapeutic effect and active targeting efficiency under 808 nm laser irradiation for MCF-7 tumor cells. Based on PCN-224 nanocarriers and aptamer MUC1, this work provides a novel strategy for precisely targeting MCF-7 tumor cells.
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MICROPOROUS AND MESOPOROUS MATERIALS
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2019
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IF 4.182
Shi-Wen Lv,Jing-Min Liu,Hui Ma,Zhi-Hao Wang,Chun-Yang Li,Ning Zhao,Shuo Wang
Nowadays efficient and rapid removal of organic dyes from wastewater is still a complicated task with great challenge. Herein, the amino groups functionalized UiO-66 (denoted as UiO-66-NH 2 ) was synthesized via a one-step process and then applied in simultaneous removal of methyl orange (MO) and methylene blue (MB) for the first time. The as-prepared UiO-66-NH 2 showed excellent adsorption ability to both MO and MB, and the maximum adsorption capacities were as high as 148.4 (MO: pH = 5, T = 25 °C) and 549.6 (MB: pH = 9, T = 25 °C) mg/g, respectively. Significantly, UiO-66-NH 2 exhibited highly pH-dependent selective adsorption for MO and MB. More interestingly, the simultaneous removal of MO and MB from the MO/MB mixture solution could be achieved by UiO-66-NH 2 under neutral condition. The adsorption mechanisms and reusability were also investigated. Overall, UiO-66-NH 2 could be a perfect candidate for removing MO and MB application in dye-containing wastewater treatment . And the results from this study also provided some new insights for the treatment of wastewater containing various dyes.
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ELECTROCHIMICA ACTA
·
2018
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IF 5.116
Yongxiang Chen,Yunjiao Li,Wei Li,Guolin Cao,Shuyun Tang,Qianye Su,Shiyi Deng,Jia Guo
The stabilities of the host and interfacial structure for layered LiNi x Co y Mn 1-x-y O 2 cathode materials are critical for their electrochemical properties, especially at high voltage. This study reports the synergetic effect of the Zr and Ti elements on the LiNi 0.5 Co 0.2 Mn 0.3 O 2 cathode material (NCM523). The as-obtained Zr/Ti modified LiNi 0.5 Co 0.2 Mn 0.3 O 2 cathode material shows the excellent electrochemical performance at high voltage. It delivers 167.3 mAh·g −1 at 1 C over 3.0–4.4 V corresponding 94.20% capacity retention after 200 cycles. Moreover, the rate capability of Zr/Ti co-modified NCM523 at 16 C (3.0–4.4 V) rises to 139.4 mAh·g −1 and corresponding capacity retention (vs. 0.5 C) is 79.57%. In addition, its capacity retention reaches to 91.71% after 100 cycles at 1 C rate even at 3.0–4.6 V. Such superior electrochemical performances are ascribed to the Zr doping and Ti modification. The synergetic modifications of the Zr/Ti elements not only stabilize the crystal structure, but also absorb the lithium residues to form mixed Li 4 Ti 5 O 12 /Li 2 TiO 3 coating layers, which strengthen the stability of the interfacial structure and the kinetic characteristics of the cathode materials.
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JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2018
·Vol. 102
·期 3
·1414-1424
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IF 2.956
Yaowu Wei,Tao Zhang,Qi Zhang,Bingqiang Han,Nan Li
Improving the hydration resistance of CaO aggregates is the key to successful application of lime-based refractories in metallurgical industry. Additive Zr(OH) 4 and Al(OH) 3 were introduced in the preparation of CaO granules using granulation equipment and calcination method in this study. The results showed that the hydration resistance of CaO granules was improved significantly, especially for granules with 0.6 wt.% Zr(OH) 4 and 0.9 wt.% Al(OH) 3 , respectively. The shell of CaO granules was relatively dense after calcination and the volume of open pores of CaO granules decreased from 3.56 × 10 −2 to 1.80 × 10 −2 cm 3 /g when additive was introduced. Zr(OH) 4 and Al(OH) 3 have the opposite effect on the closed porosity of CaO granules, the closed porosity of CaO granules was decreased with Zr(OH) 4 addition, but increased with Al(OH) 3 addition.
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OPTICAL MATERIALS
·
2018
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IF 2.32
Zhenzhen Zhou,Guanghui Liu,Jia Ni,Wanlu Liu,Qian Liu
A kind of novel compound Ba 1-x (Zr,Ti)Si 3 O 9 :xEu simultaneously activated by different-valence Eu 2+ and Eu 3+ ions has been successfully synthesized. The existence of Ti 4+ -O 2- charge transfer (CT) transitions in Ba 1-x ZrSi 3 O 9 :xEu is proved by the photoluminescence spectra and first principle calculations, and the Ti 4+ ions come from the impurities in commercial ZrO 2 raw materials. Under the excitation of multi-wavelength ultraviolet radiation (λ EX = 392, 260, 180 nm), Ba 1-x ZrSi 3 O 9 :xEu (x = 0.15) can directly emit nearly white light. The coexistence of multiple luminescent centers and the energy transfer among Zr 4+ -O 2- CT state, Ti 4+ -O 2- CT state, Eu 2+ and Eu 3+ ions play important roles in the white light emission. Ba 1-x ZrSi 3 O 9 :xEu (x = 0.15) has good thermal stability, in particular, the intensity of emission spectrum (λ EX = 392 nm) at 150 °C is ∼96% of that at room temperature. In general, the multi-wavelength ultraviolet-excited single-phase white light emitting phosphor Ba 1-x (Zr,Ti)Si 3 O 9 :xEu possesses a promise for applications in white light emitting diodes (WLEDs), agriculture, medicine and other photonic fields.
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