Polymers
·
2019
·Vol. 11
·期 12
·2023
·
IF 3.164
Haoguo Yue,Lingqian Kong,Bo Wang,Qing Yuan,Yan Zhang,Hongmei Du,Yunyun Dong,Jinsheng Zhao
Three soluble conjugated polymers, named BEDPP, FLDPP, and CADPP, were prepared through the Suzuki polymerized reaction, and employed benzene (BE), fluorene (FL), and carbazole (CA) as the donor units, respectively. The electron-deficient molecule 2,5-bis-(2-octyldodecyl)-3,6-bis-(5-bromo-thiophene)-pyrrole[3-c]pyrrole-1,4-diketone(DPP) was introduced and used as the acceptor unit. The properties of these three copolymers were studied by a series of detailed characterization analysis, including X-ray photoelectron spectroscopy (XPS), colorimetry, electrochemical measurements, spectroelectrochemistry, kinetics, quantitative calculation, and thermogravimetric (TG) analysis, etc. The results revealed that BEDPP displayed a blue color in the neutral state and a light brown color in the oxidized state, FLDPP exhibited a cyan color in the neutral state and a gray color in the oxidized state, while CADPP displayed pure blue color in the neutral state and a light gray color in the oxidized state. All these polymers possess narrow optical band gaps lower than 1.80 eV and satisfactory thermal stability. The kinetic characterization showed that the optical contrasts (ΔT%) in the near-infrared region were superior to the visible region. The optical contrasts of BEDPP, FLDPP, and CADPP are 41.32%, 42.39%, and 45.95% in the near-infrared region, respectively, which made them a good application prospect in the near-infrared region. Amid the three polymers, CADPP has the highest coloration efficiency (around about 288 cm2·C−1) and fast switching times (0.77 s in the coloring process and 0.52 s in the bleaching process) in the visible region, and the comprehensive performance of CADPP can be comparable to that of the reported D-A (Donor-Acceptor) type blue color polymers. In general, based on the good performances and the stable neutral blue color, the three polymers had profound theoretical significance for the development of electrochromic material and the completion of the RGB (Red, Green, Blue) color space.Keywords:electrochromic;pyrrole[3-c]pyrrole-1,4-diketone;donor-acceptor;neutral blue color;conjugated polymer
研究领域:
材料科学
·
化学
✓ 已验证
DOI
PubMed
高影响因子
EES Catalysis
·
2025
·
IF 8.1
Jie Yang,Lifang Chen,Xuya Zhu,Wenwen Shi,Mengxue Huang,Chang Liu,Ruimin Ding,Lin Gan,Xi Yin
H2O2 -related electrochemical reactions, including two-electron oxygen reduction reaction (2e-ORR), H2O2 oxidation reaction (HPOR), and H2O2 reduction reaction (HPRR), have received significant attention for the electrosynthesis H2O2 and energy storage. Understanding the complex structure-activity relationships among 2e-ORR/ HPOR/HPRR and their connections is crucial for further developing highly efficient catalysts and working systems. Herein, we unveil these intricacies by employing model Co-N-C catalysts with well-defined active site configuration (Co-N4-pyrrolic and Co-N4- pyridinic ) in a combined experimental and computational approach. We report the higher 2e-ORR/HPOR but lower HPRR activity of CoN4-pyrrolic site than the CoN4-pyridinic site based on their reaction free energy landscapes remodeled considering the chemisorption steps of O2 and H2O2 . The results reveal that the binding free energy of *OOH (ΔG*OOH ) can only be utilized as a reliable descriptor for 2e-ORR/HPOR activity, but not indicative of HPRR activity, regardless of the scaling relationship of the common reaction intermediates ( *OOH or *OH). The HPRR activity of CoN 4 sites strongly depends on the H2O2 adsorption strength and configuration. These findings provide valuable insights into the design of catalysts for H2O2 -related electrochemical energy conversion and storage systems.
研究领域:
电化学
·
催化
·
材料科学
·
能量转换与存储
·
计算化学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Energy Chemistry
·
2022
·
IF 13.599
Xin Wu,Xingyu Xiong,Bin Yuan,Jun Liu,Renzong Hu
A good cycling stability is a prerequisite for the application of metal-based materials in lithium-ion batteries (LIBs). However, an abnormal increase in capacity is often observed, which has rarely been focused on in many studies. In our SnSe-Mo-C composite anode, a high reversible capacity of 737.4 mAh g −1 remained after 5000 cycles at 5 A g −1 between 0.01 and 3.0 V versus Li/Li + . However, a continuous capacity increase occurred in the initial cycles, with 1086.9 mAh g −1 after 1000 cycles and 1216.9 mAh g −1 after 1500 cycles, respectively. Further studies revealed that the electrolyte decomposed at high potentials (2.5–3.0 V) and provided additional capacities. The cut-off voltage and electrolyte filling were controlled, which eliminated the impact of electrolyte decomposition, prevented rapid capacity decay, and provided a stable cycling performance for SnSe-Mo-C anodes in LIBs. This work shows that the composite anode is promising for lithium storage and the findings provide new insights into understanding and controlling the phenomenon of capacity increase with cycling in metal-based anode materials.
研究领域:
材料科学
·
电化学
·
能源存储
·
纳米材料
·
电池技术
✓ 已验证
DOI
高影响因子
Nanoscale
·
2016
·Vol. 9
·期 1
·334-340
·
IF 7.76
Meng Yang,Yanlei Liu,Wenxiu Hou,Xiao Zhi,Chunlei Zhang,Xinquan Jiang,Fei Pan,Yuming Yang,Jian Ni,Daxiang Cui
Human-induced pluripotent stem cells (iPS) possess an intrinsic tumor tropism ability. However, iPS cells are impeded in clinical applications of tumor therapy due to the formation of teratomas and their survival in normal organs such as the liver, lungs, spleen and kidneys. Mitomycin C (MMC) can overcome this limitation by suppressing iPS proliferation. Herein, we fabricated a safe delivery system of iPS cells treated with MMC loading with gold nanorods (AuNRs) for the targeted photothermal treatment of gastric cancer. Our results showed that the tumor cells were efficiently killed by the heat generated from the gold nanorods, and the iPS cells ultimately died due to the action of MMC seven days after the photothermal treatment. This suggested that pre-treated iPS cells with MMC can be used as a novel and safe approach for targeted tumor therapy. This paves the road for clinical translation in the future.
研究领域:
生物医学工程
·
癌症研究
·
纳米技术
·
干细胞生物学
✓ 已验证
DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
·
2022
·
IF 5.436
Zhiyong Bai,Lehui Liu,Zhoubin Lin,Kang Min Ok
A novel guanidinium-templated ultraviolet (UV) nonlinear optical zinc carbonate crystal, [C(NH2)3]2Zn(CO3)2 (GZCO), has been synthesized in a closed system at low temperatures. GZCO crystallizing in the tetragonal noncentrosymmetric nonpolar space group, P41212 exhibits a three-dimensional anionic framework constructed by interconnected [Zn6C6O32] 12-membered ring channels with inorganic CO3 triangles and ZnO4 tetrahedra. Notably, the anhydrous GZCO shows a very high thermal stability among guanidine-based hybrid NLO materials benefiting from the confinement effect of the organic cations within inorganic channels. The UV–visible transmittance spectrum reveals that GZCO has a short UV cutoff edge of 210 nm, corresponding to the large band gap of 5.9 eV. GZCO exhibits a mild second-harmonic generation efficiency of 0.5 × KH2PO4 with type-I phase-matching behavior.
研究领域:
材料科学
·
光学
·
化学
✓ 已验证
DOI
高影响因子
NANOTECHNOLOGY
·
2023
·Vol. 34
·期 14
·145704
·
IF 3.5
Jin Tan,Ling Lan,Yan-ni Wu,Song-bai Qiu
The graphene-like wrapped Ni@C catalysts were facilely synthesized by a modified sol–gel method. Nickel nitrate and citric acid (CA) were adopted as the raw materials to form sol–gel mixture. Under the circumstances, the additive CA were employed not only as a complexing agent but also as a carbon source. It is found that the calcination temperature and the mole ratios between Ni and CA are the key factors affecting the physical property and the catalytic performance of catalysts in the conversion of nitroarenes into corresponding anilines. The results show that the Ni@C-500(1:1) catalyst exhibited the best performance in the hydrogenation of o-chloronitrobenzenes (o-CNB) to o-chloroanilines (o-CAN). The yield of o-CAN was achieved at 100% when o-CNB was completely converted at 40.0 °C under 2.0 MPa H2 for 2.0 h. Furthermore, the Ni@C-500(1:1) catalyst could be separated and recovered easily after reaction by an external magnetic field. The investigated results indicate that the Ni@C-500(1:1) catalyst remained higher activity after using twelve times. More importantly, this kind of catalyst is also active for the selective hydrogenation of other nitroarenes into the corresponding anilines. This new synthetic method may pave a way for producing low-cost Ni@C catalysts on a large scale, which is attractive for industrial anilines applications.
研究领域:
化学工程
·
材料科学
·
催化
·
有机化学
✓ 已验证
DOI
高影响因子
Jove-Journal of Visualized Experiments
·
2024
·
IF 1.2
Miao Cui,Lijuan Jiang,Wei Yang,Wenfeng Zhang
The lethality of liver cancer and the resistance to chemical drugs have forced the search for effective prescriptions of traditional herbs for liver cancer. Animal models that are repeatable, easy to manipulate, and highly mimic the pathophysiological processes of liver cancer are the prerequisite for the successful screening of effective drug candidates. Meanwhile, reliable drug efficacy evaluation indicators and means are also the guarantee of anti-liver cancer drug research and development.Sanleng Jiashen formula, a representative prescription of traditional Chinese medicine containing Sparganium stoloni erum, Buch. -Ham. (Sanleng), Panax ginseng C. A. Mey. (ginseng), Rheum officinale Baill. (rhubarb), and Ligusticum chuanxiong Hort. (Chuanxiong), is prescribed to nourish the liver and clear heat, remove toxins, and promote blood circulation to treat liver cancer. This experimental protocol describes the preparation of lyophilized Sanleng Jiashen formula and the establishment process of in-situ liver cancer in BALB/c-nu mice. Histopathological staining, immunohistochemical detection of cancer markers, in vivo imaging of mice, and chick embryo chorioallantoic membrane test were used to explore the inhibition and anti-angiogenesis effect of Sanleng Jiashen formula on malignant proliferation of liver cancer tissue. The data show that the Sanleng Jiashen formula can effectively resist the malignant proliferation of liver cancer tissue, which is manifested by reduced tumor mass volume, improved pathological damage, and lower levels of the cancer marker ki67.The superior inhibition of angiogenesis also suggests that the Sanleng Jiashen formula may have the potential to treat and prevent the progression and deterioration of liver cancer. The whole experimental scheme shows a comprehensive process of traditional Chinese medicine components in the treatment of mouse liver cancer, which provides a reference for the establishment and optimization of a liver cancer model, as well as the research and development of drugs to prevent and treat liver cancer.
研究领域:
肿瘤学
·
药理学
·
中医药
·
动物模型
·
分子生物学
·
组织病理学
✓ 已验证
DOI
PubMed
高影响因子
RARE METALS
·
2024
·Vol. 43
·期 5
·2053-2066
·
IF 9.6
Lai Jia-Mei,Zou Zhi-Min,Bai Yu,Xing Yu-Tao,Jiang Chun-Hai
Surface modification of graphite anode with electroactive matters has been proven of a more practical strategy in enhancing the performance of Li-ion batteries than exploring alternative novel anode materials. Herein, rutile TiNbO 4− x nanoparticles with a tunnel structure are employed as multifunctional decoration substances in combination with a carbon coating layer to improve the rate and cycle properties of mesocarbon microbeads (MCMBs). As compared to pristine MCMB, the Li + diffusion coefficients of the composite anodes are enhanced due to the synergistic effect of TiNbO 4− x @C. Meanwhile, the overcharge and voltage polarization of the composite anodes at high rate are obviously minimized due to the current sharing effect of the high-potential TiNbO 4− x . Moreover, the amorphous Li y TiNbO 4− x converted from TiNbO 4− x in the initial lithiation process can deliver pseudocapacitive capacity to the composite anodes from the second cycle. All of these functions of TiNbO 4− x @C coating layer have directly contributed to the improved rate and cycle performance of the MCMB/TiNbO 4− x @C composite anodes. The one containing 12.0 wt% TiNbO 4− x exhibits a high reversible specific capacity of 118 mAh·g −1 at 10C (1C = 372 mA·g −1 ), together with a high capacity retention of 90.9% after 300 cycles at 3C, which are all much superior to those of pristine MCMB. Graphical abstract
研究领域:
材料科学
·
电化学
·
纳米技术
·
储能
✓ 已验证
DOI
高影响因子
Current Pharmaceutical Analysis
·
2020
·Vol. 16
·期 6
·763-773
·
IF 0.923
Yaro Peter,Nie Jing,Xu Mingcheng,Zeng Kui,Zeng Su
Background: Terpene lactones are major components of ginkgo biloba extract which are used in cardiovascular and degenerative diseases. To study the involvement of transporters in the transport/disposition of ginkgolides A, B, C, and bilobalide, a bioanalytical assay was developed by
LCMS/ MS system for the quantitation of intracellular levels of terpene lactones in cells expressing organic cation transporter 2 (OCT2). Methods: The assay involved an optimized simple sample handling with methyl tert-butyl ether for liquid-liquid extraction and reconstitution in modified
dissolution solution. Pretreatment of samples with 50 μM ascorbic acid and the addition of ascorbic acid and formic acid in dissolution solution significantly reduced matrix effect and stabilized the postpreparative samples. Separations were performed by Zobrax RRHD column (extend-C18 1.8μm,
3.0 x 100mm) and acetonitrile gradient elution. The analysis was carried out in the negative ion scan mode using multiple reaction monitoring. Results: The method was validated for linearity (concentration range of 20-5000nM), accuracy (±13.1%), precision (<11.0%), recovery
(94.31–105.9%), matrix effect (93.8-111.0%) and stability. Finally, the method was applied in the determination of intracellular concentrations of ginkgolides A, B, C, and bilobalide in Madin-Darby canine kidney (MDCK-mock) and MDCK-OCT2 cells in uptake study. Conclusion: The developed
method was successfully validated. Results suggest that OCT2 is involved in the renal disposition of ginkgolide A, B, and bilobalide. This method would foster the study of transport mediated activity via the interaction of ginkgolides and bilobalide with cellular systems.
研究领域:
药理学
·
分析化学
·
药物代谢
✓ 已验证
DOI
高影响因子
JOURNAL OF ORGANIC CHEMISTRY
·
2024
·
IF 3.3
Jin Yan,Suijie Zhong,Xu Chen,Yihuan Luo,Hua Cao,Xiang Liu,Limin Zhao
Here, we report controlled and site-selective C–H alkenylation and dialkenylation of indolizines and pyrrolo[1,2-a]quinolines with β-alkoxyvinyl trifluoromethylketones under simple and practical conditions. Moreover, this direct C–H alkenylation strategy can also be extended to imidazo[1,2-a]pyridines. Notably, without a transition metal and external oxidant, efficient dehydrogenative β-alkenylation of tertiary amines with β-alkoxyvinyl trifluoromethylketones is presented.
研究领域:
有机化学
·
合成化学
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2020
·
IF 4.939
Wenyu He,Jinhui Wei,Ting Huang,Enren Zhang
For practical applications of microbial fuel cells (MFCs), 5H-dibenz [b,f] azepine-5-carboxamide (Carbamazepine, CBZ) was used as the organic precursor for the synthesis of catalysts composed of Fe–N–C complexes (named as Fe-CBZ-Cats) through a sacrificial support method. Characterizations by SEM, XPS and TEM-EDS elemental mapping show that the synthesized Fe-CBZ-Cats have porous structure and uniformly dispersed Fe/N/C complex centers which could play key roles in effective ORR . Linear scanning voltammetry (LSV) measurements show that the synthesized Fe-CBZ-Cats exhibits ORR activity comparable to commercial Pt/C catalysts under the same catalyst loading (2 mg cm −2 ). The maximum power density produced by cathode-limiting MFCs with Fe-CBZ-Cats air cathodes was 431 ± 23 μW cm −2 , higher than those in the control MFCs with Pt/C air cathodes (403 ± 13 μW cm −2 ) and activated carbon air cathodes (296 ± 24 μW cm −2 ). In addition, the toxicity tolerance of the synthesized Fe-CBZ-Cats is much higher than Pt/C.
研究领域:
环境科学
·
电化学
·
生物工程
✓ 已验证
DOI
高影响因子
BIOORGANIC CHEMISTRY
·
2020
·
IF 4.831
Shiyang Zhou,Gangliang Huang
In this study, a series of novel 7 H -benzo [ c ] [1,3] dioxolo [4, 5- f ] chromen-7-one derivatives were obtained by structural modification of the lead compounds with Fissitungfine B. A total 15 compounds were designed, synthesized and evaluated as inhibitors of tumor. These target compounds have the novel chemical structures that named three six-membered rings including one lactone six-membered ring. In vitro assay, the results showed that the target compounds have a broad spectrum and strong of anti-tumor activity. Such as the target compound 4n to MCF-7 was IC 50 = 0.35 ± 0.01 μM, to A-549 was IC 50 = 0.37 ± 0.01 μM, to Hela was IC 50 = 0.56 ± 0.02 μM, to MDC-803 was IC 50 = 0.53 ± 0.02 μM and COLO-205 was IC 50 = 0.50 ± 0.02 μM in vitro . At the same time, in vivo anti-tumor activity assay results showed that the target compounds had a good inhibitory effect on tumor growth. Among them, the target compound 4n had the best anti-tumor activity, it could inhibit tumor growth well at a low dose. The target compound 4n could be used as a candidate drug for further research and development, in order to be used as early as application in the clinical treatment of tumors.
研究领域:
药物化学
·
肿瘤学
·
有机合成
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）