Micromachines
·
2021
·Vol. 12
·期 9
·1116
·
IF 2.891
Shuiqin Chai,Lijia Zhou,Shuchen Pei,Zhiyuan Zhu,Bin Chen
It is a major challenge to effectively inhibit microbial pathogens in the treatment of infectious diseases. Research on the application of nanomaterials as antibacterial agents has evidenced their great potential for the remedy of infectious disease. Among these nanomaterials, carbon quantum dots (CQDs) have attracted much attention owing to their unique optical properties and high biosafety. In this work, P-doped CQDs were prepared by simple hydrothermal treatment of m-aminophenol and phosphoric acid with fluorescence emission at 501 nm when excited at 429 nm. The P-doped CQDs showed effective antibacterial activity againstEscherichia coli(E. coli) andStaphylococcus aureus(S. aureus). The minimal inhibitory concentrations (MICs) of P-doped CQD were 1.23 mg/mL forE. coliand 1.44 mg/mL forS. aureus. Furthermore, the morphologies ofE. colicells were damaged andS. aureusbecame irregular when treated with the P-doped CQDs. The results of zeta potential analysis demonstrated that the P-doped CQDs inhibit antibacterial activity and destroy the structure of bacteria by electronic interaction. In combination, the results of this study indicate that the as-prepared P-doped CQDs can be a promising candidate for the treatment of bacterial infections.Keywords:carbon quantum dots;biocompatibility;antibacterial activity
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高影响因子
MATERIALS & DESIGN
·
2020
·
IF 6.289
Lei Miao,Tingting Jiang,Shudong Lin,Tao Jin,Jiwen Hu,Min Zhang,Yuanyuan Tu,Guojun Liu
p -Aramid is an ideal building block for forward osmosis (FO) membranes due to its extraordinary thermal resistance, chemical stability, and mechanical properties. However, existing aramid membranes have certain limitations such as large pore diameters and low salt rejection rates. In this work, we describe a facile solvent exchange-delay phase inversion strategy to prepare p -aramid nanofibrous membranes that would be suitable for FO applications. In this strategy, p -aramid nanofibers with an average diameter of 16 ± 4 nm and an average length of 382 ± 89 nm were employed as membrane matrices. Prior to the immersion of the cast film into a coagulation bath, a pre-evaporation protocol was carefully designed and introduced to provide a slower exchange rate between the good solvent and the non-solvent, which delayed the demixing process between p -aramid nanofibers and thus yielded an asymmetric membrane with a denser active layer as well as a loose substrate layer. The resultant membrane showed excellent FO water flux, NaCl rejection ratios, tensile strength, thermal properties, and solvent resistance. The membrane reported in this work may provide a promising candidate for separation applications and the results reported herein will facilitate the development of high-performance nanofibrous membranes.
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Advanced Composites and Hybrid Materials
·
2025
·Vol. 8
·期 1
·1-12
·
IF 21.8
Yao Feichong,Xie Wenhao,Zhao Xiqiu,Gu Hongbo
With the advent of the information age, wearable thermoelectric fabric devices have garnered significant attention for their ability to harness environmental waste heat and body heat to supply convenient, reliable, and environmentally friendly electricity for next-generation wearable electronics. However, the complex production process and unstable power supply restrict their development. Here, we report a high-performance flexible, dependable, and wearable p-type thermoelectric device consisting of silk threads/polyaniline/amino multiwalled carbon nanotubes through dyeing process. By optimizing the weaving structure and simple assembly, this p-type fabric device generates a voltage of 0.749 ± 0.003 mV, a maximum power of 0.326 ± 0.007 nW, and a power density of 1087.532 ± 22.985 nW·m −2 at a temperature difference of 90 ℃. Besides, this device also possesses an excellent photo-thermoelectric conversion capability and the assembled fabric bracelet can generate an output voltage of approximately 6.1 mV outdoors when worn on the hand of the experimental personnel. This fabric device also exhibits a superb reliable property even after 5000 times of folding. This strategy makes it easy to manufacture a thermoelectric fabric device on a large scale and provides a promising way for wearable electronics.
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POLYCYCLIC AROMATIC COMPOUNDS
·
2016
·
IF 0.959
Hongyun Nie,Maiqian Nie,Yongzhe Yang,Jing Zhao,Xinyi Zhang,Yutao Guo,Yi Wan,Jing Zi
Characterization of phenol metabolization by P. stutzeri N2 was proposed based on the identification of relevant metabolites and enzyme activities of catechol 1,2-oxygenase and catechol 2,3-dioxygenase. P. stutzeri N2 started to grow on 400 mg l−1 phenol with no obvious lag phase, and then phenol decomposition was rapidly completed within 32 h. Results of enzyme activities, UV spectrums of cultures, and the mass spectrum identification of cis, cis-muconic and 2-HMS, which showed that catechol C12O and C23O were acting simultaneously on the fission of the phenol ring. The existence of P-hydroxybenzoic acid and straight-chain saturated dicarboxylic acids in the culture medium showed that carboxylation and hydrogenation were involved during the phenol degradation. Metabolites containing five or four carbons indicated that catechol and its immediate ring-cleavage intermediates could be furthermore metabolized by P. Stutzeri N2. Therefore, P. stutzeri N2 which could degrade phenol with high efficiency and diverse pathways could have potential applications in the treatment of wastewater containing phenol.
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WATER RESEARCH
·
2014
·
IF 5.323
Huajun Feng,Xueqin Zhang,Yuxiang Liang,Meizhen Wang,Dongsheng Shen,Yangcheng Ding,Baocheng Huang,Jiali Shentu
p -Fluoronitrobenzene ( p -FNB) tends to accumulate in industrial effluents because of its recalcitrant properties. Approaches to the removal of p -FNB always encounter conflicts between treatment efficiency and economic efficiency. A bioelectrochemical system (BES) was established to facilitate the removal and mineralization of p -FNB. The treatment cost was reduced by using inexpensive electrode materials and reducing the electrical energy used. p -FNB was effectively removed using the BES, and the reaction rate was higher than the sum of the rates of two control systems, i.e., a biological system (BS) and an electrocatalytic system (ECS), by a maximum of 62.9% under a voltage of 1.4 V. The voltage is a crucial kinetic factor for the BES performance; as the voltage increased from 0 to 1.4 V, the reaction rate constants for p -FNB removal and defluorination increased from 0.0520 to 0.1811 h −1 and 0 to 0.0107 h −1 . The synergistic effect of multistrains gave a TOC removal efficiency in the BES of about 34.05%, yet the removal efficiencies were low for the two control. The defluorination reaction rate was significantly slower than the p -FNB removal rate, which indicated that defluorination lagged p -FNB removal, and p -FNB transformation to p -fluoroaniline ( p -FA) was the fastest step. The electrochemical assistance provided electrons and accelerated the electron transfer rate in the microbial reduction of p -FNB to p -FA. In this study, the critical voltage for defluorination in the BES was 0.8 V, which was approximately 0.2 V lower than that in the ECS. The decrease in the critical voltage for defluorination was based on the production of p -FA, which is more electrocatalytically activated. These results demonstrate the mechanism of efficient p -FNB removal and mineralization in a BES.
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高影响因子
COLLOID AND POLYMER SCIENCE
·
2020
·Vol. 298
·期 8
·1053-1061
·
IF 1.536
Cai Shuwei,Gu Shiyu,Li Xian,Wan Songhan,Chen Songbo,He Xianru
A controlled grafting modification starch exhibited tunable phase transition temperature in aqueous solution was prepared via reversible addition–fragmentation chain transfer (RAFT) polymerization and esterification reaction under mild condition. P(AM/AN) copolymer was grafted onto the starch backbone and endowed the grafted copolymer thermosensitivity. The molecular structure and composition of P(AM/AN) copolymers were characterized by gel permeation chromatography (GPC), FTIR, and NMR, indicating a structurally controllable side chain of the grafted copolymer. Results of X-ray diffraction (XRD) demonstrate that the crystallinity of grafted copolymer decreases compared with starch due to side chains destruct the structural regularity of starch. Scanning electron microscopy (SEM) images show that grafted copolymer displays a rough, multilayer, and irregular morphology. Dynamic light scattering (DLS) and UV tests indicate that the grafted copolymer forms aggregates in aqueous solution and the UCST of the grafted copolymer is dependent on percent grafting (PG) and molecular interactions of side chains.
研究领域:
高分子化学
·
材料科学
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PLoS One
·
2025
·Vol. 20
·期 5
·e0322835
·
IF 2.6
Fujie Xu,Xiaohang Shan,Jialin Li,Jing Li,Jiqiao Yuan,Daozeng Zou,Manyuan Wang
Artemisinin-based combination therapies (ACTs) constitute the principal strategy for combating malaria in contemporary times, and research into the multifaceted components of Artemisia annua L. ( A. annua ) has garnered widespread interest among scientists. The aim of this study was to prepare A. annua extracts (nACTs) and to explore whether nACTs have higher bioavailability and efficacy than artemisinin (ART) alone due to its multiple bioactive components. Initially, the in vivo antimalarial activity of nACTs was evaluated by two murine malaria models. The results revealed that the antimalarial effect of nACTs was about 10-fold higher than that of ART alone when administered at the same dosage of ART. Then, we analyzed the pharmacokinetic characteristics of nACTs in rat plasma. Remarkably, nACTs exhibited significantly enhanced oral bioavailability, longer half-life as well as extended mean retention time in rats. In addition, the impact of nACTs on P-glycoprotein (P-gp) was evaluated using the Caco-2 cell line. The results showed that both ART and nACTs reduced the efflux rate of the P-gp substrate rhodamine 123 (R123) and induced the expression of P-gp in Caco-2 cells over a range of concentrations. nACTs had certain components-deoxyartemisinin (DEART), artemisinic acid (AA), and dihydroartemisinic acid (DHAA)-that inhibited the efflux and translocation of P-gp and facilitated the reduction of ART efflux. In conclusion, A. annua extracts significantly improved the antimalarial efficacy and bioavailability compared with ART.
研究领域:
药理学
·
寄生虫学
·
植物化学
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高影响因子
ACS Applied Energy Materials
·
2022
·
IF 6.959
Yiyuan Ding,Xin Ren,Dong Chen,Fanjue Wen,Ting Li,Fei Xu
Rechargeable Mg batteries have the advantages of abundant reserves and high safety, but suitable inorganic cathodes are quite limited. Organic polymers break the hindrance of the inorganic Mg-storage crystal lattice and provide more selections, but the reports on organic rechargeable Mg battery cathodes are relatively few. Herein, high-capacity bipolar organic cathodes are developed for rechargeable Mg batteries. Poly(1,5-diaminoanthraquinone) with double polyaniline chains is used as a bipolar cathode. The carbonyl and amino groups are employed as the N-doping and P-doping centers, respectively, and the conjugated anthraquinone unit delocalizes the charge density change during the redox reactions. Considering the mass of Mg salt, the poly(1,5-diaminoanthraquinone) cathode provides a high corrected capacity of 267 mA h g–1 (non-corrected capacities of 297 mA h g–1) for bipolar reactions. Moreover, compared with the single-chained poly(1-aminoanthraquinone) (44% capacity maintained after 140 cycles), the double-chained poly(1,5-diaminoanthraquinone) shows a much better N-doping cycleability (97% capacity maintained after 300 cycles), as the double polyaniline chains enhance the structure stability during the Mg-storage reaction. The present study demonstrates the importance of a large conjugated double-chain structure to enhance the Mg-storage performance of organic polymers. It is also imagined that the bipolar organic materials with both of N- and P-dopings are a highly promising strategy for development of high-capacity organic Mg battery cathodes.
研究领域:
材料科学
·
电化学
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高影响因子
NANOTECHNOLOGY
·
2020
·Vol. 31
·期 25
·255501
·
IF 3.551
Huapeng Wang,Mingpeng Chen,Qian Rong,Yumin Zhang,Jicu Hu,Dongming Zhang,Shiqiang Zhou,Xinbo Zhao,Jin Zhang,Zhongqi Zhu,Qingju Liu
Xylene is a volatile organic compound which is harmful to the human health and requires precise detection. The detection of xylene by an oxide semiconductor gas sensor is an important research direction. In this work, Co3O4 decorated flower-like SnO2 nanorods (SnO2/Co3O4 NRs) were synthesized by a simple and effective two-step method. The SnO2/Co3O4 NRs show high xylene response (Rg/Ra = 47.8 for 100 ppm) and selectivity at the operating temperature of 280 °C, and exhibit high stability in continuous testing. The resulting SnO2/Co3O4 NRs nanocomposites show superior sensing performance towards xylene in comparison with pure SnO2 nanorods. The remarkable enhancement in the gas-sensing properties of SnO2/Co3O4 NRs are attributed to larger specific surface area and the formation of p–n heterojunction between Co3O4 and SnO2. These results demonstrate that particular nanostructures and synergistic effect of SnO2 and Co3O4 enable gas sensors to selectively detect xylene.
研究领域:
材料科学
·
环境科学
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Biosensors-Basel
·
2026
·Vol. 16
·期 6
·303
·
IF 6.2
Yu Chen,Lina Dong,Hengyan Tian,Fei Yang,Dengbang Jiang,Minglong Yuan
Magnetic polymeric microspheres are pivotal solid-phase carriers in chemiluminescence enzyme immunoassays (CLEIA). However, their practical clinical application is frequently hindered by non-specific adsorption, irreversible aggregation, and the intrinsic susceptibility of exposed outermost Fe3O4nanoparticles to oxidation. To overcome these critical bottlenecks, we rationally engineered highly original monodisperseP(St-MMA)@Fe3O4@P(St-MMA) sandwich-structured microspheres. The bespoke amphiphilic outer shell acts as an impenetrable shield against hydration and oxidation, while maintaining a topologically size-matched mesoporous network (average pore size of 13.11 nm) for optimal antibody anchoring. Strikingly, this architecture ensures exceptional long-term colloidal stability, completely preventing macroscopic agglomeration for over six months in buffer solutions. When evaluated in a carcinoembryonic antigen (CEA), CLEIA, our microspheres achieved an ultra-low limit of detection (LOD) of 0.055 ng·mL−1and high analytical recovery (93.37–108.25%). In a head-to-head comparison with industry-standard commercial magnetic beads, the engineered microspheres delivered stronger chemiluminescent signals and lower background noise, demonstrating excellent intra-assay (CV < 4.37%) and inter-assay (CV < 10%) precision. This work establishes a scalable, highly stable materials platform that effectively resolves the persistent oxidation limitations, holding immense practical importance for next-generation ultrasensitive clinical in vitro diagnostics.
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高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Tao Zhao,Dazhong Zhong,Lu Tian,Genyan Hao,Guang Liu,Jinping Li,Qiang Zhao
Designing efficient electrocatalysts to improve the overall water splitting and urea electrolysis efficiency for hydrogen generation can greatly solve the dilemma of energy shortage and environmental pollution. In this work, Co 8 FeS 8 @CoFe–MOF/NF heterojunction arrays were fabricated by embedding sulfides into the surface of metal-organic frameworks (MOFs) nanosheets as multifunctional electrocatalyst. The introduction of sulfide on CoFe–MOF/NF can not only adjust the electronic structure (electron-rich state) and change the surface properties (more hydrophilic), but also increase the active area to enhance the catalytic activity. The in situ Raman shows Co 8 FeS 8 @CoFe–MOF/NF is more easily to generate active species at low potentials and generates a higher content of active β-MOOH phase than CoFe–MOF/NF. Therefore, the Co 8 FeS 8 @CoFe–MOF/NF exhibits excellent oxygen evolution reaction (OER) performance with an overpotential of 213 mV at 10 mA cm −2 . Furthermore, when used as a urea oxidation reaction (UOR), only an ultralow potential of 1.311 V at 10 mA cm −2 . More importantly, the assembled two-electrode drives overall water splitting and urea electrolysis with cell voltages of 1.62 V and 1.55 V at 10 mA cm −2 , respectively. This work provides insights into the preparation of electrocatalysts with multifunctional heterostructure arrays for hydrogen production.
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高影响因子
MATERIALS CHARACTERIZATION
·
2022
·
IF 4.537
Shuang Liu,Limin Ma,Cheng Zhen,Yishu Wang,Dan Li,Fu Guo
In advanced microelectronic packaging technology, the interfacial brittleness of Cu/Sn solder joints puts forward higher requirements for high-performance diffusion barriers. Cobalt–Phosphorus (Co-P) alloy coating becomes ideal candidates for its good wettability and diffusion resistance. In this work, for Co-P with different crystallinity , the barrier properties of electrodeposited Co-P coatings as well as the mechanical properties of Co-Sn intermetallic compounds (IMCs) at the Co-P/Sn-Ag interface were investigated. According to the XRD results, the crystallinity of the Co-P coating was directly related to the phosphorus (P) content, and Co-P were classified into three types: crystalline state, mixed state and amorphous state. The morphology, composition, phase characterization, and mechanical properties of the Co-Sn IMCs at the interface were investigated by SEM , EPMA , TEM , and nanoindentation methods, respectively. After 180 °C aging test for 120 h, the thickness of CoSn 3 generated at the interface of crystalline Co-4.2 at.% P/Sn-Ag was the smallest among a total of 18 Co-P coatings, where P content ranged from 0.9 at.% to 20.8 at.%, showing the best barrier properties. The hardness of (Co,Cu)Sn 3 at the amorphous Co-P/Sn-Ag interface was the lowest (3.2 GPa), which was only 47% of that of Ni 3 Sn 4 , exhibiting the lowest brittleness tendency. The mixed crystalline-amorphous Co-P could greatly improve the diffusion barrier properties while sacrificing a small degree of brittleness comparing to the amorphous coatings, and had the potential to become a general-purpose alloy coating. This work could provide a scientific basis for the selection of Co-P barrier layers with excellent barrier properties and mechanical properties leading to different application scenario in electronic packaging.
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