SENSORS AND ACTUATORS B-CHEMICAL
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2016
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IF 4.758
Zongen Liu,Jiecheng Xiao,Xianwei Wu,Liqing Lin,Shaohuang Weng,Min Chen,Xiaohui Cai,Xinhua Lin
This work reports a facile and effective approach for preparing graphene quantum dots co-doped with nitrogen and sulfur (N-S/GQDs). The proposed method comprised pyrolysis of citric acid with glutathione and dialysis treatment. The fabricated N-S/GQDs exhibited blue luminescence and a high fluorescence quantum yield of 36.3%. N-S/GQDs can be sensitively quenched by Fe 3+ , which was absorbed on the edge of N-S/GQDs through the coordination interaction between Fe 3+ and N, S elements. The subsequent introduction of pyrophosphate ion (PPi) resulted in the recovery of the fluorescence of Fe 3+ -quenched N-S/GQDs. The stronger coordination reactivity between Fe 3+ and PPi induced changes in fluorescence. PPi concentration was facilely quantified through the recovered amplitudes of the fluorescence intensities of N-S/GQDs. Under the optimized experimental condition, increased fluorescence intensity showed a linear relationship to PPi concentration (1 μM to 1000 μM) in serum samples. Additionally, the proposed method featured sensitive and selectivity for the detection of PPi in synovial fluid, suggesting the potential application for simple and accurate clinical diagnosis of arthritic diseases.
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LANGMUIR
·
2025
·
IF 3.9
Daqiang Liu,Xingliang Yin,Leilei Li,Chuanwu Chen,Qiu-Xia Lin,Hong-Xin Zhang,Erkang Liu,Jun-Feng Wang
Ammonia is in high demand and widely used, yet its production still predominantly relies on the energy-intensive Haber–Bosch process, highlighting the urgent need for a milder alternative technology. Photocatalytic N2 fixation shows great promise in this regard despite the challenge of developing high-efficiency catalysts. In this study, we successfully prepared micronano spherical Bi2MoO6/Bi2MoO6–x S-Scheme homojunctions using a simple solvothermal-calcination coupling method, which offer unique advantages for nitrogen fixation catalysis: (i) the micronano structure mitigates the agglomeration issue common in nanomaterials, thereby exposing more active sites; (ii) the in situ constructed S-Scheme homojunction features a high-quality surface and interface structure, enhancing the spatial separation and transport of photogenerated charges and preserving strong redox capabilities; and (iii) the oxygen-rich vacancy structure promotes the N2 adsorption and activation. Thanks to those favorable properties, the Bi2MoO6/Bi2MoO6–x (BMO/BMOOV) S-Scheme homojunction demonstrates exceptional ammonia production efficiency, with a NH4+ generation rate of 238.7 μmol g–1 h–1 under simulated sunlight, which is over 5.2 times higher than that of pristine Bi2MoO6 (BMO) and significantly outperforms other reported similar catalytic systems (see Table S1). This work introduces a simple and versatile method for synthesizing homojunctions, potentially inspiring the development of more efficient photocatalysts for nitrogen fixation and beyond.
研究领域:
光催化
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材料科学
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环境化学
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可再生能源
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固氮
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JOURNAL OF LIPID RESEARCH
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2025
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IF 4.1
Shaojun Pei,Wen Wang,Tingze Feng,Qiuping Wang,Yuhan Wang,Hong-Xu Liu,Xinmiao Liang,Hai-long Piao
S -palmitoylation is a dynamic and reversible post-translational modification that plays crucial roles in cancer progression. Here, we found the oncogene of metadherin (MTDH) modulates lipid metabolism and ferroptosis by its S -palmitoylation. We demonstrate that MTDH is S -palmitoylated at Cys-75 in the endoplasmic reticulum by ZDHHC1/9 and S -depalmitoylated by APT1. The flexible loop and the α-helix length in the MTDH N-terminus affect its S -palmitoylation level. In addition, metabolomics analysis found that the S -palmitoylated MTDH increases intracellular levels of triglycerides, phosphatidylethanolamines, and phosphatidylcholines. However, the non- S -palmitoylation form of MTDH-CS enhanced the interaction of between MTDH and the ferroptosis enhancer of Acyl-CoA synthetase long-chain family member 4 (ACSL4), thereby reducing ferroptosis sensitivity in breast cancer cell. Taken together, targeting MTDH S -palmitoylation may represent a novel strategy for breast cancer therapy.
研究领域:
癌症生物学
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分子生物学
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细胞生物学
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脂质代谢
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翻译后修饰
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2025
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IF 4.1
Heng-xue Zhou,Yi Long,Qiu-fang Zhong,Jia-liang Wang,Bo Liang,Ying-bang Yao,Daniel Q. Tan,Sheng-guo Lu,Tao Tao
A novel V 2 O 3 @C/S composite cathode material is prepared via a combined strategy consisting of solution synthesis, hydrothermal treatment and high-temperature carbonization, and all solid-state lithium‑sulfur (Li S) batteries with high-performance are constructed. The obtained V 2 O 3 @C host material demonstrates excellent properties, including good structural stability, superior electrical conductivity, strong interfacial compatibility, notable sulfur adsorption and high catalytic capabilities. At a current rate of 0.1C, the V 2 O 3 @C/S cathode delivers an initial capacity of 1125 mAh g −1 with a capacity retention of 67.1 % after 150 cycles in solid-state cells at the room temperature. At 0.5C, the capacity retention still remains 45.5 % after 250 cycles. Cyclic voltammetry, electrochemical impedance spectroscopy, and Tafel analysis further demonstrate the enhanced reaction kinetics and reduced charge-transfer resistance. This work provides a promising strategy for designing the high-performance cathode materials of solid-state Li S batteries.
研究领域:
材料科学
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储能
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电化学
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纳米材料
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电池技术
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FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES
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2025
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IF 1.8
Xiao Song,Rui Xiong,Runqian Yang,Yining Jiang,Qian Chen,Liping Ruan
Biomass carbon materials have good application prospects in the field of electromagnetic wave absorption and shielding because of their environmental protection and low cost, but not good absorption of low-frequency S-band. In this article, the microwave activation of different mass ratios of zinc chloride and peach pit carbon is studied to improve the low-frequency wave absorption performance. It is found that with the addition of zinc chloride, the electromagnetic absorption performance of peach pit carbon in S-band is significantly improved after microwave activation. The sample with a mass ratio of zinc chloride to peach pit carbon of 3:1 has the best performance. Its minimum reflection loss (RL) is −14.13 dB (4.60 mm, 3.92 GHz), and the maximum effective absorption bandwidth is 1.24 GHz (2.10–3.34 GHz, 5.80 mm). The results of scanning electron microscopy (SEM), X-ray powder diffraction (XRD) and other tests show that the absorption properties of S-band are closely related to the ZnO and basic zinc chloride components generated by microwave activation. In this study, the absorption of carbon material in S-band is achieved by simple microwave activation without the addition of magnetic materials, which can provide a new way for the low-frequency absorption enhancement of materials.
研究领域:
材料科学
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电磁学
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环境功能材料
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纳米碳材料
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能源与环境技术
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Polymer Chemistry
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2017
·Vol. 8
·期 21
·3261-3270
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IF 5.375
Jun Zhang,Yan Xiao,Xueli Luo,Lianlei Wen,Andreas Heise,Meidong Lang
Double hydrophilic block copolymers (DHBCs) based on poly(ε-caprolactone)s, poly(6-acetoxyl-ε-caprolactone)-b-poly(4-N-piperilactone) (PCCL-b-PPIL), were synthesized via ring-opening polymerization and deprotection. The self-assembly behaviour of these block copolymers in aqueous solutions was thoroughly explored via a combination of UV-vis spectroscopy, zeta potential measurement, 1H NMR spectroscopy, dynamic light scattering (DLS) and transmission electron microscopy (TEM). It was observed that “schizophrenic” aggregations were formed and triggered by pH, i.e., the copolymers could self-assemble into PCCL-core micelles at acidic pH and PPIL-core micelles at alkaline pH. In addition, pendant groups in each block of copolymers facilitated further chemical modification with fluorescent dyes such as 1-(hydroxymethyl)pyrene and FITC. The fluorescence properties of pyrene-functionalized copolymers were closely related to their aggregate morphology, which could be adjusted simply by altering the environmental pH values. Meanwhile, it is expected that this novel type of degradable schizophrenic block copolymer holds potential application in stimuli-responsive fluorescent probes.
研究领域:
高分子化学
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纳米医学
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生物材料
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药物递送
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分子影像
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刺激响应系统
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Molecular Catalysis
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2026
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IF 4.9
Ting He,Panting Song,Jinshu Wang,Junshu Wu,Jiawei Xiao,Yongli Li
Graphitic carbon nitride (g-C 3 N 4 ) has emerged as a promising metal-free photocatalyst for solar driven hydrogen evolution. However, the rapid recombination of photogenerated electron-hole pairs in pristine g-C 3 N 4 severely limits its opportunities for practical application. Herein, we developed an intramolecular S-scheme with an endogenous built-in electric field (BIEF) via simply ethylenediamine-mediated two-step thermal polycondensation, producing an heteroaromatic-modified g-C 3 N 4 (HA-CN). The experimental results showed this structural innovation achieves dual optimization: (1) molecular-level integration of aromatic ring-modified melon (A-domain) and pristine melon-skeleton (P-domain) establish a BIEF to promote carriers transfer and separation; (2) the aromatic substitution extends π-electron delocalization of the adjacent melon domains, enhancing n→π* transitions and broadening visible-light absorption. The optimized HA-CN exhibited exceptional enhancement of hydrogen evolution (5.99 mmol g⁻¹ h⁻¹, λ ≥ 420 nm), surpassing pristine g-C 3 N 4 by 39-fold, with an apparent quantum efficiency (AQE) of 3.93 % at 420 nm. Time-resolved spectroscopy and electrochemical analysis confirm the suppressed charge recombination and reduced interfacial charge-transfer resistance, corresponding to BIEF-driven directional carrier migration. This research offers valuable insights into junction engineering strategy from molecular level for designing efficient photocatalysts.
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Small
·
2026
·
IF 11.8
Kainan Hong,Yutao Lu,Fuyao Huang,Yichi Zhang,Zihao Zhou,Yuanyuan Zheng,Ya Huang,Huisheng Peng,Peining Chen
Electronic textile is a promising platform for next-generation wearable systems, where transparent conductive fibers are essential building blocks for optoelectronic functions. Current transparent conductive fibers are typically realized by coating conductive nanomaterials onto a polymer fiber substrate. However, this strategy generally suffers from weak interfacial adhesion and thus causes conductivity degradation under mechanical deformations or environmental exposure. In this work, we report a high-performance transparent conductive fiber based on disulfide-functionalized thermoplastic polyurethane. Silver nanowires (AgNWs) react with sulfur atoms in the disulfide groups to form robust Ag-S covalent linkages, thereby stabilizing the AgNWs network. The resulting fibers exhibit a balanced combination of high conductivity (2.7 × 10 3 S/m) and optical transmittance (81%). Their conductivity and optical transmittance can be tuned by adjusting the AgNWs loading, while maintaining high transparency and superior mechanical durability under harsh conditions, including 1000 cycles of bending, twisting, and abrasion. We further integrate these fibers into electroluminescent fibers and display textiles through wrapping or weaving. These devices exhibit high brightness, uniform emission, and long-term operational stability. This interfacial engineering strategy improves compatibility between conductive networks and flexible polymers, enabling high-performance electronic fibers and textiles.
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TALANTA
·
2026
·
IF 6.7
Linzi Huang,Xiaoqian Sun,Kunxiang Deng,Meijun Ni,Xinyi Li,Yixi Xie,Pengcheng Zhao,Junjie Fei
Flutamide (FLU), a nonsteroidal antiandrogen drug for prostate cancer therapy, requires sensitive monitoring due to its narrow therapeutic window. Herein, we constructed a novel photoelectrochemical sensor based on an S-scheme Bi 2 S 3 /FeIn 2 S 4 heterojunction for ultrasensitive FLU detection. This charge transfer mechanism was confirmed through density functional theory calculations and electron paramagnetic resonance tests. FLU can act as a hole scavenger by transforming its nitro group into a nitroso derivative via a 2e − /2H + transfer process, thereby amplifying the photocurrent signal. The sensor outperformed traditional techniques, exhibiting a wide dual-range linear detection capability (0.02 - 20 μM and 20 - 110 μM) with an ultralow detection limit of 10 nM. The designed sensor exhibits good repeatability and long-term storage stability (>92.8%). Moreover, this sensor was successfully applied in human serum and urine, with recovery rates ranging from 96.9% to 100.2%.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 8.3
Longlong Wang,Sirong Sun,Xingyu Jin,Jiayu Cheng,Heng An,Zhou Yang,Xueji Zhang,Haifeng Dong,Xiangdan Meng
Rapid and reliable detection of Staphylococcus aureus ( S. aureus ), a major foodborne pathogen, remains a critical challenge in food safety surveillance. Here, we present a hybrid electrospinning–CHA–SERS biosensing platform that integrates aptamer-functionalized electrospun nanofibers with catalytic hairpin assembly (CHA)-mediated assembly of gold nanoparticles (GNPs) for ultrasensitive detection of S. aureus . The electrospun nanofibers enable efficient bacterial enrichment through their high-surface-area architecture, while CHA-triggered GNPs aggregation generates dense plasmonic “hotspots” for remarkable Raman enhancement. This synergistic design achieves a record-low detection limit of 9.2 CFU/mL, along with high specificity and stability in complex food matrices. Demonstrated in real samples, this work establishes a new signal amplification paradigm that couples enzyme-free nucleic acid assembly with SERS enhancement, offering a powerful strategy for intelligent food safety monitoring and rapid pathogen diagnostics.
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CHINESE JOURNAL OF CATALYSIS
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2026
·
IF 17.2
Xiaoqian Wang,Feifan Zhao,Wantian Mei,Jianjun Zhang,Chuanbiao Bie,Jiaguo Yu,Hermenegildo Garcia,Feiyan Xu
Efficient S-scheme photocatalysis requires not only favorable band alignment but also sufficiently strong interfacial driving forces to direct photogenerated carrier migration across the junction. Local donor-acceptor (D-A) coordination and global Fermi-level equilibration are shown to cooperate in the dark to precondition interfacial energetics and thereby promote subsequent S-scheme charge transfer. A molecularly coupled heterojunction is constructed by integrating a triazine-imine covalent organic framework (TPT-COF) with ZnO quantum dots through interfacial Zn–N coordination. Spectroscopic analyses reveal that D-A-induced local electron redistribution and Fermi-level-equilibration-driven compensating charge redistribution coexist in the dark, cooperatively enlarging the effective interfacial energy offset and reinforcing the internal electric field prior to illumination. Ultrafast spectroscopy further shows that this preconditioned interface accelerates S-scheme charge transfer under light irradiation, enabling efficient spatial charge separation while preserving strong redox potentials. As a result, the optimized COF/ZnO heterojunction achieves selective CO 2 photoreduction to CH 4 without external photosensitizers or sacrificial agents. These findings identify a cooperative mechanism by which local coordination chemistry and interfacial electrostatics jointly regulate S-scheme energetics, offering a molecular strategy for designing adaptive photocatalytic interfaces for solar fuel production.
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BioDesign Research
·
2025
·
IF 4.7
Peiling Wu,Haofeng Chen,Guojun Yang,Haoyu Qin,Qian Zhang,Yuxin Chen,Dongjiang Lin,Yang Zhang,Shuyong Lin,Shizhen Wang,Jifeng Yuan
2-Hydroxyisovalerate (2-HIV) is a value-added chemical that is widely applied in the synthesis of bioactive compounds and polymers. Here, we report an underexplored metabolic route for the de novo production of S -type 2-HIV ( S -HIV) in Escherichia coli . In particular, we identified promiscuous activity of 4-hydroxymandelate synthase (HmaS) from Amycolatopsis orientalis towards the conversion of 2-keto-4-methyl-pentanoate (2-KMP, an immediate precursor for L-leucine) to S -HIV. Next, we designed a variant HmaS (S201F) with abolished activity for mandelate and 4-hydroxymandelate synthesis, thereby minimizing byproduct formation. Coupled with systematic optimization of the L-leucine biosynthetic pathway, we achieved de novo production of S -HIV at 8.1 mM (0.95 g/L) in shake flasks and 33.9 mM (4.0 g/L) in 2-L fed-batch fermentation. In summary, this work represents the first time to realize the efficient synthesis of S -configuration 2-HIV in metabolically engineered E. coli .
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