JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2021
·
IF 8.067
Jing Zhang,Sunxiang Qian,Lingdong Chen,Liqun Chen,Liping Zhao,Jie Feng
Hydrogels with good antifouling and mechanical properties as well as biocompatibility have great application potential in the field of biomedicine. In this paper, a newly double network (DN) hydrogel was prepared based on zwitterionic material sulfobetaine methacrylate (SBMA) and natural polysaccharide , sodium alginate (SA). The PSBMA network is covalently crosslinked while the SA network is ionically crosslinked by Ca 2+ . The hybrid crosslinked double network structure endows the DN hydrogel with excellent mechanical properties ( E = 0.19 ± 0.01 MPa, σ = 0.73 ± 0.03 MPa), fast self-recovery ability as well as excellent fatigue resistance . Moreover, the results show that the PSBMA/SA-Ca 2+ DN hydrogel is biocompatible and resists the absorption of non-specific proteins and adhesion of microorganisms, such as cells and algae, exhibiting outstanding antifouling properties. These unique characteristics of PSBMA/SA-Ca 2+ DN hydrogel make it a promising candidate for biomedical application, such as artificial connective tissues, implantable devices , and underwater equipment.
✓ 已验证
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2019
·
IF 5.155
Yu-Zhuang Gao,Tian-Xiao Chang,Yi-Xian Wu
Biomass sodium alginate (SA) and biomass-derived ether tetrahydrofuran (THF) have drawn considerable attention due to their sustainability and bio-renewability. In this paper, the novel acylated sodium alginate- g -polytetrahydrofuran graft copolymers (ASA- g -PTHF) with various PTHF branches ( M n,PTHF = 600–4800 g/mol, G N = 3–20 per 1000 SA monosaccharide) could be successfully synthesized by combination of THF living cationic ring-opening polymerization with grafting-onto method. The microphase separation of ASA- g -PTHF graft copolymer formed via self-assembly from two kinds of segments in backbone and side chains and was emphasized by thermal annealing, leading to a remarkable increase in water contact angle on polymer surface even by 38.4°. The hydrophilicity and crystallization behavior of ASA- g -PTHF can be decreased with increasing M n,PTHF and G N , which confine the crystallization of graft copolymer. ASA- g -PTHF microspheres (~1 μm) loaded with ibuprofen shows pH sensitivity and reach 100% of drug-release at pH = 7.4 within 30 h. ASA- g -PTHF exhibits resistance to bovine serum albumin adsorption and its composite with small-scaled silver nanoparticles (Ag-NPs, <2.6 wt%, 5–15 nm) generated in - situ behaves good antibacterial performance against E. coli and S. aureus . The ASA- g -PTHF would contribute to the better utilization of biomass and has promising for biomedical applications.
✓ 已验证
DOI
高影响因子
Gels
·
2026
·Vol. 12
·期 10
·899
·
IF 6.4
Haifeng Zhang,Guangfu Chen,Hao He,Xia Zhu,Tonggang Liu
Solar-driven interfacial evaporation offers a low-energy and sustainable route for seawater desalination and the purification of complex water matrices. However, freestanding hydrogel evaporators often suffer from insufficient mechanical robustness and interfacial salt accumulation under high-salinity conditions. Herein, a spunlace cotton nonwoven/sodium alginate/bamboo charcoal (SC/SA/BC) composite interfacial evaporator was fabricated through a facile impregnation–ionic crosslinking strategy, using a spunlace cotton nonwoven (SC) as the reinforcing scaffold, sodium alginate (SA) as the hydrophilic hydrogel matrix, and bamboo charcoal powder (BC) as the photothermal component. The Ca2+-crosslinked SA network immobilized the bamboo charcoal particles and formed continuous hydrated mass-transport pathways, while the spunlace fibrous network provided capillary water-supply channels and robust mechanical support. Consequently, SC/SA/BC exhibited substantially improved mechanical performance compared with the freestanding SA/BC hydrogel. Under 1 sun irradiation using a 3.5 wt% NaCl solution, SC/SA/BC achieved an evaporation rate of approximately 1.80 kg m−2h−1and maintained stable performance during 8 h of continuous operation. The evaporation–condensation process markedly reduced the concentrations of major ions in natural seawater and effectively retained nonvolatile dyes. Through the synergistic integration of a spunlace fibrous scaffold, a hydrated hydrogel network, and a bamboo-charcoal-based photothermal component, the proposed evaporator simultaneously achieved mechanical reinforcement, sustained water supply, efficient photothermal conversion, and salt-tolerant operation. This work provides a promising strategy for constructing structurally stable and readily fabricated solar interfacial evaporation materials.
✓ 已验证
DOI
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2026
·
IF 2.6
Yanze Zhu,Yuanqing Ma,Zhihaote Yu,Peicheng Chen,Changxin Shi,Shubin Li,Weli Xu,Xiaojun Han
The bacterial infection is a major issue in the field of chronic wound healing. It is important to design a hydrogel material with good biocompatibility, water retention and antibacterial properties for the problem of bacterial infection. In this work, a dual-network antibacterial hydrogel (GSAH) with Ag+, thiolized gelatin (Gel-SH) and sodium alginate (SA) was prepared. Gel-SH formed the first network of the hydrogel through metal coordination bonds with Ag+. The metal coordination bonds between SA and Ag+ formed the second network. The compressive stress of GSAH was 660.95 KPa, and the swelling equilibrium was reached at 12 h with a swelling rate of 10.4%. The complete degradation of the hydrogel within 24 h indicated its biodegradability. The antibacterial results showed that the inhibition zones of GSAH against E. coli and S. aureus were 17.2 ± 1.6 mm and 9.5 ± 0.5 mm, respectively. GSAH holds potential for antibacterial dressing in the biomedical field.
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Chaoping Fang,Jingtao Mei,Xiaohua Wu,Licong Yang
Water-soluble antioxidants exhibit strong activity but limited effectiveness in edible oils due to poor lipid solubility and short residence time. In this study, a food-grade sodium alginate–chitosan hydrogel bead system encapsulating curcumin-loaded selenium nanoparticles (Cur@Se) was developed to enhance antioxidant delivery and stability in lipid matrices. The Cur@Se-loaded bead(chitosan concentration 5 mg/mL) formed a dense crosslinked network with improved mechanical strength (65% increase in hardness), high encapsulation efficiency (98%), and enhanced anti-swelling capacity (20%), enabling sustained release in the oil phase. This bead exhibited strong antibacterial activity against Staphylococcus aureus and Escherichia coli . Schaal oven tests demonstrated this hydrogel bead significant oxidative protection in soybean oil, reducing peroxide, acid value, p-anisidine, and total oxidation values by 31%, 39%, 33%, and 53%. Comparable protection was observed in rapeseed oil. This work highlights a food-grade, dual-functional delivery strategy integrating sustained release, interfacial antioxidant activity, and antimicrobial effects, providing a promising alternative to synthetic antioxidants for edible oil preservation.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
FOOD RESEARCH INTERNATIONAL
·
2026
·
IF 8
Pengrui Wu,Xindi Wei,Zhihong Song,Chunling Nie,Zhonghui Shen,Yijun Liu,YanBo Wang,JianGuo Wang,Hong Zeng
Developing environmentally friendly delivery systems capable of encapsulating, protecting, and promoting the absorption of bioactive components in the human body is crucial for those with low oral bioavailability and poor stability. This study developed W/O/W emulsion-filled sodium alginate (SA) hydrogel for the co-delivery of hydrophilic riboflavin and hydrophobic curcumin. Firstly, W/O/W emulsion was prepared using peanut protein isolate (PPI)-bacterial cellulose nanofibers (BCNFs) as the hydrophilic emulsifier and lecithin as the lipophilic emulsifier, and the effect of stabilizer concentrations on emulsion stability was investigated. Results showed that PPI and BCNFs self-assembled into stable complexes through electrostatic interaction and hydrogen bonding, thereby improving the emulsification properties of PPI. Subsequently, SA was added to the outer aqueous phase of emulsions, and its influence on emulsion properties and stabilization mechanism was investigated. SA significantly improved the stability and rheological properties of PPI-BCNFs-stabilized W/O/W emulsions. Finally, the loading capacity of this system for riboflavin and curcumin and its gastrointestinal fate were evaluated. We found this delivery system efficiently co-delivered both hydrophilic and hydrophobic bioactive components and improved their photostability and thermal stability. Moreover, the bioaccessibilities of riboflavin and curcumin were significantly increased to 61.97% and 45.66%, respectively. This was attributed to SA forming a composite interfacial layer on droplets and a dense gel network in the continuous phase, thereby acting as a physical barrier to better protect the encapsulated components. This delivery system holds promise for the development of functional foods incorporating multiple nutraceuticals.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TENSIDE SURFACTANTS DETERGENTS
·
2021
·Vol. 58
·期 5
·342-352
·
IF 1.049
Haiyan Gao,Yue Zhou,Jianguo Wang,Hujun Xu
A temperature-sensitive hair dye was prepared with a poloxamer-sodium alginate mixture. When the hair dye was applied to the hair (< 32 °C), it retained its flow dynamics. The hair dye was able to undergo a phase change and formed a solid as soon as it touched the scalp (32°C), which reduced the transdermal amount of p -phenylenediamine (PPD) and also adverse effects and toxicity. Compared to a conventional hair dye, the temperature-sensitive hair dye achieved a reduction of the transdermal amount of p -phenylenediamine by almost 65% at different concentrations. At the same time, the colouring effect was not significantly reduced. The poloxamer alginate hydrogel can be used as a novel colouring material to reduce the harm of the dye intermediate to the human body when colouring hair.
研究领域:
化妆品科学
·
毒理学
·
材料科学
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2019
·
IF 4.784
Zhuqing Wang,Shasha Wu,Yuenan Zhang,Lijing Miao,Yujie Zhang,Aiguo Wu
A low-cost, environment-friendly sodium alginate-meso-2,3-dimercaptosuccinic acid hybrid aerogel (SA-DMSA) was synthesized by simple chemical grafting and vacuum freeze-drying method and used to remove heavy metal ions in wastewater. The as-prepared SA-DMSA showed high affinity for heavy metal ions, such as Pb 2+ , Cd 2+ , Cu 2+ , Cr 3+ , and Co 2+ , and can remove >90% of the metal ions from the corresponding solution. SA-DMSA also exhibited high selectivity to Pb 2+ and Cd 2+ , and the maximum adsorption capacities for Pb 2+ and Cd 2+ reached 116.4 and 91.2 mg/g, respectively. The SA-DMSA adsorbent can be regenerated by a simple one-step acid washing, and the adsorption performance remained stable after repeated use. Given its low-cost and easy-to-obtain raw materials, simple preparation process, and simple regeneration process of the adsorbent, SA-DMSA has broad application prospects in the treatment of low-concentration heavy metal ions, especially for wastewater containing Pb 2+ and Cd 2+ .
研究领域:
环境科学
·
材料科学
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Yurou Feng,Amatjan Sawut,Rena Simayi,Xieraili Maimaitiyiming,Xueying Jiao
With the advancement of science and technology, the issue of wastewater pollution has escalated, necessitating urgent attention to wastewater treatment . In this study, a highly efficient adsorbent for Cu 2+ was successfully synthesized through in situ self-assembly using Ca 2+ as the cross-linking agent in ZIF-8@ALG composite hydrogel. The results demonstrated that the incorporation of Ca 2+ as the cross-linker enhanced both adsorption capacity and swelling properties of ZIF-8@ALG composite hydrogel. Adsorption performance evaluation revealed that the hydrogel followed pseudo-second-order kinetic model for Cu 2+ adsorption and Freundlich isotherm model with a theoretical maximum adsorption capacity of 309.57 m g −1 . Thermodynamic analysis indicated that Cu 2+ adsorption onto the hydrogel occurred spontaneously with heat absorption. Furthermore, excellent reusability was observed after five cycles of usage without significant loss in adsorption efficiency. Overall, these findings highlight the potential application of ZIF-8@ALG composite hydrogel as an effective solution for wastewater remediation and recovery of heavy metal ions.
研究领域:
环境科学
·
材料科学
·
化学工程
·
环境污染治理
·
重金属去除
✓ 已验证
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 56
·51068-51077
·
IF 3.289
Junhao Huang,Jiacheng Li,Yuhong Feng,Fei Xiang,Rui Wang,Jianbo Wu,HuiQiong Yan,Kai Chen,Qingfeng Zhou,Yanfeng Liu
The interaction of cholesteryl-grafted sodium alginate derivative (CSAD) and decyl-β-D-glucopyranoside (DGP) in solution was studied through the surface tension method, fluorescence spectroscopy, electron paramagnetic resonance (EPR), and dynamic light scattering. Results showed that DGP and CSAD exhibit competitive adsorption behaviour at the water–gas interface and that this competitive behaviour can be intensified by NaCl. EPR revealed that the cholesterol groups of CSAD participate in the formation of micellar structures. The steric effect of the cholesterol groups reduces the microviscosity of the micellar structure, but high-concentration NaCl can weaken the polarity and increase the microviscosity of the formed micellar structure. In addition, at a high DGP concentration, high-concentration NaCl can facilitate DGP precipitation; this condition causes abnormal phenomena of surface tension, fluorescence spectroscopy, and EPR. For the emulsion system, analysis of particle size and rheology indicated that DGP and CSAD form a network structure between oil and water interfaces through interaction and thus enhance the non-Newtonian fluid properties of the emulsion. Owing to the competitive adsorption between CSAD and DGP at the oil–water interface, DGP gradually replaces CSAD with the increase in DGP concentration. With a further increase in DGP concentration, the stable steric effect of polymers between oil drops may disappear, and oil drops may aggregate mutually.
研究领域:
生物化学
·
表面化学
·
胶体科学
✓ 已验证
DOI
高影响因子
DALTON TRANSACTIONS
·
2024
·
IF 3.5
Liyang Lin,Mengjun Li,Ying Yan,Yuanhao Tian,Juan Qing,Susu Chen
The volume expansion and poor conductivity greatly limit the application of silicon as an anode for lithium-ion batteries. Although nanocrystallization of silicon and its surface carbon coating can be improved to some extent, the serious problems of particle aggregation and structural instability have not been effectively solved. In this paper, gelatin and sodium alginate (GE + SA) derived carbon/silicon composites are successfully prepared by a liquid-phase method, the freeze-drying technique, and heat treatment. Si nanoparticles (NPs) are uniformly encapsulated in a three-dimensional network of N-doped carbon that is enriched with a rich pore structure. The reversible capacity of the particular Si@C composite electrode was maintained at 580 mA h g−1 after 300 cycles at a current density of 1 A g−1, showing good cycling stability. Meanwhile, the anode also has excellent rate performance with reversible capacities of 2230, 1458, 1101, and 686.6 mA h g−1 at current densities of 0.1, 0.5, 1, and 2 A g−1, respectively. The GE + SA derived carbon/silicon composites effectively solve the problems of particle aggregation and an unstable carbon/silicon interface structure and can become candidates for anode materials in lithium-ion batteries.
研究领域:
材料科学
·
能源存储
·
电化学
✓ 已验证
DOI
高影响因子
Applied Materials Today
·
2026
·
IF 6.9
Ruiwen Zhou,Yuchen Li,Yi Jiang,Miqi Hu,Zhaohui Li,Yu-E Lian,Hui Gao,Lanmei Chen,Dongdong Sun
The rapid emergence of antibiotic resistance and resilient bacterial biofilms poses a critical threat to global public health. To address this challenge, we developed SA-GDL-Ru—a novel sodium alginate hydrogel integrated with a synthesized ruthenium(II) complex ( Ru , RuCl(η⁶-C₆H₆)(TolBig)). This hydrogel overcomes the poor aqueous solubility and toxicity limitations of traditional metal complexes while enhancing antibacterial efficacy. In vitro studies demonstrated potent activity against Staphylococcus aureus (MIC = 13.90 μM) and Escherichia coli (MIC = 20.85 μM), with the SA-GDL-Ru hydrogel (SGR-2) exhibiting 6–8-fold greater reactive oxygen species (ROS) induction than Ru alone. Transcriptomic analysis revealed that SA-GDL-Ru downregulates fabH (fatty acid synthase) and sigB (biofilm synthesis) genes while upregulating quorum-sensing regulators (agrA/agrC), disrupting biofilm integrity. Molecular docking confirmed Ru ’s binding affinity with biofilm-associated proteins, inhibiting key enzymatic functions. Crucially, SA-GDL-Ru accelerated wound closure in S. aureus -infected mice by 4 days through EGFR/Akt pathway activation, increasing VEGF-A/HIF-1α and reducing Caspase-3 expression. In acute pneumonia models, it achieved near-complete bacterial eradication with suppressed inflammation. Safety assessments confirmed minimal cytotoxicity (< 25 μM in zebrafish) and no hemolysis or organ damage. This work establishes SA-GDL-Ru as a translatable therapeutic platform combating biofilm-mediated infections while promoting tissue regeneration.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）