Frontiers in Immunology
·
2021
·
IF 7.561
Wang Yue,Zhao Yan,Wang Zhecheng,Sun Ruimin,Zou Boyang,Li Ruixi,Liu Deshun,Lin Musen,Zhou Junjun,Ning Shili,Tian Xiaofeng,Yao Jihong
Pyroptosis is a newly discovered form of cell death. Peroxiredoxin 3 (PRX3) plays a crucial role in scavenging reactive oxygen species (ROS), but its hepatoprotective capacity in acetaminophen (APAP)-induced liver disease remains unclear. The aim of this study was to assess the role of PRX3 in the regulation of pyroptosis during APAP-mediated hepatotoxicity. We demonstrated that pyroptosis occurs in APAP-induced liver injury accompanied by intense oxidative stress and inflammation, and liver specific PRX3 silencing aggravated the initiation of pyroptosis and liver injury after APAP intervention. Notably, excessive mitochondrial ROS (mtROS) was observed to trigger pyroptosis by activating the NLRP3 inflammasome, which was ameliorated by Mito-TEMPO treatment, indicating that the anti-pyroptotic role of PRX3 relies on its powerful ability to regulate mtROS. Overall, PRX3 regulates NLRP3-dependent pyroptosis in APAP-induced liver injury by targeting mitochondrial oxidative stress.
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DOI
PubMed
高影响因子
INTERNATIONAL IMMUNOPHARMACOLOGY
·
2022
·
IF 5.714
Huangming Zhuang,Bin Li,Ting Xie,Changgeng Xu,Xunshan Ren,Fuze Jiang,Tianrun Lei,Panghu Zhou
Background Osteoarthritis (OA) is a degenerative disease characterized by chronic inflammation. Indole-3-aldehyde (3-IAld) is a tryptophan metabolite secreted by intestinal flora, which can exert anti-inflammatory effects in multiple inflammatory diseases. However, the potential therapeutic role of 3-IAld in OA and the underlying mechanism remain to be explored. Methods IL-1β was utilized to induce chondrocytes inflammation. Then, cell counting kit-8 was carried out to assess the cytotoxicity of 3-IAld on rat chondrocytes viability. Meanwhile, RT-qPCR, Western blot, and immunofluorescence were performed to evaluate the expression of inflammatory factors, matrix-degrading enzymes and matrix synthesis protein, and the NF-κB pathway in chondrocytes treated with IL-1β alone, with 3-IAld or with siRNA-AhR. Results Our results showed that 3-IAld did not affect cellular viability at concentrations up to 50 μM. 3-IAld significantly inhibited the expression of pro-inflammatory cytokines (IL-6, iNOS and COX-2), and matrix-degrading enzymes (MMP3, MMP13 and ADAMTS5), upregulated the expression of matrix synthesis protein (aggrecan and collagen-II), and inactivated the NF-κB pathway in IL-1β-treated chondrocytes. However, AhR knockdown could totally abolish the aforementioned therapeutic capabilities and the inactivation of the NF-κB pathway induced by 3-IAld. Conclusions 3-IAld reduced inflammation through the AhR-NF-κB signalling pathway in IL-1β-induced chondrocytes, which is expected to provide a new therapeutic strategy for OA.
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DOI
PubMed
高影响因子
SENSORS AND ACTUATORS A-PHYSICAL
·
2021
·
IF 3.407
Xiaoying Pan,Jun Hu,Jialiang Li,Yufei Zhai,Song Li,Min Wang,Takashiro Tsukamoto,Shuji Tanaka
The temperature dependent photoluminescence of temperature sensitive paint (TSP) makes it an attractive candidate for infrared (IR) thermal imaging, but its low luminescence intensity and poor photostability hinder its extensive use in infrared detectors . Herein, a novel complex luminophore of AgNPs/[Ru(phen) 3 ]Cl 2 /PVDF was designed to fabricate a thermal imaging device with improved sensitivity and signal-to-noise ratio. It is found that the localized surface plasmon resonance (LSPR) of silver nanoparticles (AgNPs) could enhance the local intensity of the excitation light , consequently an increase in the luminescence intensity of neighboring luminophore can be achieved. Thus, not only the fluorescence intensity of the obtained sensor array is enhanced, but the temperature sensitivity is also improved to − 4.5%/K at 20 °C, which increased by 25% compared to that of the blank film without AgNPs addition. Furthermore, the detector array is used for IR thermal imaging, which can successfully obtain the thermal images of observation object at room temperature . The minimal detectable temperature is as small as about 313 K.
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DOI
高影响因子
JOURNAL OF ORGANOMETALLIC CHEMISTRY
·
2023
·
IF 2.3
Run-Ze Yuan,Peng-Fei Cui,Guo-Xin Jin
Herein, we describe the synthesis of a series pincer-type half-sandwich complexes containing selective B(3)-H activation of m -carborane. Four pincer-type complexes containing Cp*M (M = Ir/Rh) and (η 6 -pcym)Ru metal-corner, ionic Cp*M[ m -C 2 B 10 H 9 (CS 2 CH 3 ) 2 ](CF 3 SO 3 ) (M = Ir ( 2 ), Rh ( 3 )), (η 6 -pcym)Ru[ m -C 2 B 10 H 9 (CS 2 CH 3 ) 2 ](CF 3 SO 3 ) ( 4 ) and neutral solvolysis product Cp*Ir[ m -C 2 B 10 H 9 (CS 2 CH 3 )(COS)] (Complex 5 ), have been prepared. The addition reaction of MeO − toward 2 3 and 4 causes the formation of moderately stable neutral unsymmetrical pincer-type complexes Cp*M{ m -C 2 B 10 H 9 (CS 2 CH 3 )[CS(SCH 3 )(OCH 3 )]} (M = Ir ( 6 ), Rh ( 7 )) and (η 6 -pcym)Ru{ m -C 2 B 10 H 9 (CS 2 CH 3 )[CS(SCH 3 )(OCH 3 )]} ( 8 ). The substitution reaction of 2 3 and 4 have also been also explored, unsymmetrical chelate complexes Cp*M( t BuNC)[ m -C 2 B 10 H 9 (CS 2 CH 3 ) 2 ](BPh 4 ) (M = Ir ( 9 ), Rh ( 10 )) can be obtained by using t BuNC and NaBPh 4 . All of these complexes have been characterized, including X-Ray single crystal diffraction, NMR spectroscopy, IR spectroscopy and elemental analysis methods.
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DOI
高影响因子
ENERGY & FUELS
·
2024
·
IF 5.2
Yinhui Feng,Zhaoguo Liu,Rixin Liu,Shuqi Kang,Shuyuan Zhang,Xin Guo,Shiyong Chu,Shaohua Guo
Layered transition-metal oxides are recognized for their substantial potential as cathode materials for sodium-ion batteries (SIBs), particularly in the context of large-scale energy storage systems. O′3-NaMnO2 (NMO) has received considerable attention due to its cost-effectiveness, high capacity, and adequate initial sodium content. However, its practical application is hindered by issues, such as Jahn–Teller distortion and the migration of Mn during cycling, which result in severe irreversible phase transitions and structural collapse. In this study, the entropy strategy was employed to synthesize O′3-NaMn0.8Mg0.06Ti0.06Fe0.04Al0.04O2 (NMO-MTFA), which not only stabilized the crystal structure but also enhanced both the bulk and surface/interface kinetics. NMO-MTFA delivers a high initial discharge capacity of 190 mA h g–1 and demonstrates a superior cycling performance and rate capability. The stabilization of the crystal structure is further reinforced by the strengthened Mn–O interaction, achieved through the trace doping of multiple elements. This research underscores the efficacy of the entropy strategy in optimizing the performance of layered oxide cathodes, thereby presenting a novel approach for the design of high-performance SIBs.
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DOI
高影响因子
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
·
2021
·Vol. 2021
·期 44
·4566-4571
·
IF 2.524
Wen-Dong Yao,Mei Yan,Xiao-Hui Li,Wenlong Liu,Ru-Ling Tang
Graphical A novel transition metal tellurite phosphate Cd 3 (PO 4 )(TePO 6 ) features a new type of {[TePO 6 ] 3− } ∞ chain was obtained by solid-state reactions, and its electronic structure and optical properties are studied systematically. New inorganic crystals containing multiple anions have received extensive attensions recently in view of their abilities to be potential multifunctional materials. Among them, tellurite-phosphates with simple chemical components are relatively rarely studied. Here, one novel tellurite phosphate Cd 3 (PO 4 )(TePO 6 ) was obtained through conventional soild-state reaction, and it is the first tellurite-phosphate only possessing d 10 transition metal. It crystallizes in the monoclinic space group P 2 1 / c , and its structure features an interesting {[TePO 6 ] 3− } ∞ chain constructed by corner-sharing connected PO 4 and TeO 4 tetrahedra. Meanwhile, we obtained a new phase of Cd 3 (PO 4 ) 2 and Cd 1.725 Mg 1.275 (PO 4 ) 2 in the exploration of tellurite-phosphates, and they also crystalize in the centric space group P 2 1 / c . Crystal structures, theoretical calculations on their electronic structure and birefringence have been studied, together with the IR and UV-vis-NIR diffuse reflectance spectra.
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DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Yalin Qin,Peikun Yan,Fuxuan Han,Yongcheng Zhang,Zonglin Lv,Chunming Zhou
The enhancement of both transparency and piezoelectric properties in transparent ferroelectric ceramics is a challenge. In this work, we prepared transparent 0.75Pb(Mg 1/3 Nb 2/3 )O 3 -0.25PbTiO 3 : x Pr 3+ ceramics by oxygen atmosphere sintering together with hot pressing sintering. When x = 1.5 mol%, a transparency of 68% @ 900 nm (close to the theoretical value ~71%) was achieved, and the piezoelectric properties increased to twice as much as those in undoped ceramics ( x = 0). The small average domain size (below 200 nm) that far below the visible light wavelength was believed to benefit light transmittance. Meanwhile, the minute amount of tetragonal component induced by Pr 3+ irons, was supposed to be responsible for the improved piezoelectric properties. These merits make Pr 3+ -doped 0.75PMN-0.25PT transparent ceramics promising functional materials for transparent piezoelectric devices.
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DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2019
·
IF 6.361
Jiadong Liu,Yijia Wang,Lei Wang
A polyvinylidene fluoride (PVDF) organic conductive membrane with photoelectric activity was successfully developed via printing of oxidant (FeCl 3 ·6H 2 O) layer by layer and then chemical vapor deposition (CVD) of Poly (3, 4-ethylenedioxythiophene) (PEDOT). Four kinds of membranes were prepared by changing the number of oxidant coatings layers. The structure and photoelectric properties of four membranes were well characterized. The photocurrent density of 3.7 × 10 −4 A indicated that the four-oxidant coating layers membrane achieved the best performance in photo-electricity activity. A comprehensive study of degradation efficiency under different photoelectric conditions was carried out. Results showed that the photoelectrocatalytic removal of tetracycline hydrochloride was 1.6 and 7.9 times higher than that of photocatalysis and photolysis, respectively, under a voltage of 3 V assisted with visible light irradiation. The anti-interference and stability tests in continuous filtration process demonstrated that the dissolved organic matters (DOMs) can result in a 30% fluctuation on removal rate. The streaming potential tests of DOMs adsorption on membrane surface indicated that the more obvious the adsorption phenomenon was, the degradation of tetracycline hydrochloride was weaker. The degradation intermediates were identified and pathways were proposed in this work. The photoelectrocatalysis of PEDOT modified PVDF membrane provided a new potential for water purification .
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DOI
高影响因子
JOURNAL OF ELECTRONIC MATERIALS
·
2019
·Vol. 48
·期 11
·7068-7075
·
IF 1.676
Li Shuhui,Zhou Ying,Cui Lijun,Ge Zhenhua,Feng Jing
In 2 O 3 (ZnO) k superlattice ceramics are promising oxide thermoelectric materials, as superlattice interfaces are effective in scattering phonons and filtering low-energy electrons to decrease thermal conductivity and improve the figure of merit ( ZT ) value. In this work, homologous compounds were prepared by solid-state reaction method using ZnO and In 2 O 3 as raw materials. Phase purity and crystal structure were characterized by x-ray diffraction, revealing that In 2 O 3 (ZnO) k crystallizes in an R3 m space group for odd k values and P6 3 /mmc for even k values. The study of thermoelectric (TE) properties showed that as k increased, the thickness of InO(ZnO)
+ 3
also increased, while the electrical conductivity, thermal conductivity, Seebeck coefficient, power factor and ZT value were all decreased. In 2 O 3 (ZnO) 3 samples obtained a maximum power factor of 651 μ W m −1 K −2 at 973 K, and also achieved a maximum ZT value of 0.24 at 973 K.
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DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2022
·
IF 9.221
Yiqun Zhang,Chong Wang,Fengmin Liu,Xiaoying Sun,Xinhao Guo,Lianjing Zhao,Geyu Lu
In recent years, researchers have discovered that self-assembled monolayer functionalized surfaces could improve the gas-sensing performance of semiconductor oxide-based sensors. In the present work, metal-organic framework material ZIF-8 was selected as the self-sacrificial template, and then ZIF-8 materials were calcined at a high temperature to obtain ZnO nanoparticles . Subsequently, the surface of ZnO was modified to install a single layer of 3-aminopropyltriethoxysilane (APTES). In comparison with the pure ZnO-based sensor, the sensor based on 0.5 vol% APTES/ZnO had higher response to 2-butanone. The response has remarkably improved mainly due to APTES molecules capture electrons from the surface of ZnO to widen the electron depletion layer . In addition, the amine (–NH 2 ) group of the APTES monolayer enhanced the specific interaction between the sensing material and 2-butanone, thereby the performance of the sensor was improved. After functionalization with 0.5 vol% APTES, the lower detection limit of the sensor reached as low as 200 ppb, while that of the pure ZnO-based sensor was 500 ppb.
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高影响因子
JOURNAL OF SURFACTANTS AND DETERGENTS
·
2010
·Vol. 14
·期 3
·317-324
·
IF 0.795
Cui Zheng-gang,Song Hong-xing,Yu Jun-jie,Jiang Jian-zhong,Wang Feng
Alkali-surfactant-polymer (ASP) flooding has been considered to be one of the useful tertiary oil recovery techniques. However, field tests in China have revealed that serious side effects may occur due to using alkali. Thus alkali-free SP flooding is more favorable in China. Unfortunately, surfactants effective in ASP flooding are usually ineffective in the absence of alkali and new surfactants need to be designed. In this paper N -(3-Oxapropanoxyl)dodecanamide as a pure compound and a mixture of homologues with narrow EO number distribution, synthesized by the reaction of lauroyl chloride with diglycolamine and addition of one ethylene oxide to coconut monoethanolamide respectively, are examined for their adaptability in SP flooding. It is found that, when mixed with betaines, both products can reduce Daqing crude oil/connate water interfacial tension to a magnitude of 10 −3 –10 −4 mNm −1 at 45 °C in a wide surfactant concentration range, 0.01–0.5 wt%, and oil displacement tests using natural cores indicates that a tertiary oil recovery of 18.6 ± 0.4% OOIP can be achieved by SP flooding with the N -(3-Oxapropanoxyl)dodecanamide as the main surfactant without adding any alkaline agent and neutral electrolyte. N -(3-Oxapropanoxyl)dodecanamide, as a nonionic surfactant without a cloud point and producible industrially from renewable materials, is an ideal surfactant for SP flooding in the absence of an alkaline agent.
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DOI
高影响因子
FIBERS AND POLYMERS
·
2016
·Vol. 17
·期 11
·1741-1748
·
IF 1.022
Xu Bin,Li Qiaoping,Zhuang Linghua,Wang Qiang,Li Chao,Wang Guowei,Xie Fengwei,Halley Peter J.
3-methyl-1-(ethylacetyl)imidazolium chloride ([EtMIM]Cl), was synthesized for chitosan dissolution, and the dissolution and regeneration behaviors of chitosan in [EtMIM]Cl were thoroughly investigated. The solubility of chitosan in [EtMIM]Cl was measured at temperatures ranging from 40 °C to 110 °C, based on which the thermodynamic parameters of chitosan in [EtMIM]Cl were calculated. The polarizability and hydrogen bond accepting ability was determined by solvatochromic UV/vis spectroscopy. The regenerated chitosan from [EtMIM]Cl by adding methanol was characterized by thermogravimetric analysis (TGA), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and scanning electron microscopy (SEM). Density functional theory (DFT) computations were performed to study the interactions between [EtMIM]Cl and chitobiose. Five kinds of hydrogen bonds, C-H/O, O-H/O, O-H/Cl, C-H/Cl, N-H/Cl were found, suggesting strong interactions between [EtMIM]Cl and chitobiose. In particular, the oxygen atom and the active methylene group of carboxylic ester in [EtMIM] + , formed strong hydrogen bonding with chitobiose. The molecular simulation results indicated that both the Cl − anions and [EtMIM] + cation played important roles in the chitosan dissolution process, by the disruption of native hydrogen bonds of chitosan.
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DOI
高影响因子
危险品化学品经营许可证（带存储）