FOOD CHEMISTRY
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2025
·
IF 9.8
Ziyu Gan,Jun Wang
Linalool, a key monoterpene volatile organic compound, plays a vital role in plant stress signaling and agricultural quality evaluation. Herein, we developed a portable sensing platform by integrating molecularly imprinted metal–organic framework nanozymes (MIP@His-MOF) with smartphone-assisted colorimetric analysis. Histidine-functionalized MIL-101 was designed to mimic the catalytic environment of horseradish peroxidase, while molecular imprinting introduced selective recognition sites for linalool. This dual-functional design led to a 3.9-fold increase in catalytic efficiency and significantly improved selectivity. The optimized sensor achieved a limit of detection of 0.14 ppm in solution and retained high sensitivity in a paper-based format (0.62 ppm). As a proof of concept, the paper sensor successfully differentiated black tea quality grades, showing strong correlation with GC–MS results. This work highlights a modular, low-cost, and field-deployable approach for volatile compound detection in precision agriculture and food quality monitoring.
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Foods
·
2025
·Vol. 14
·期 18
·3181
·
IF 5.1
Fuwei Guo,Yuanfang Jiao,De Zhang,Zhi Yu,Dejiang Ni,Han Huang,Yuqiong Chen
The genusCitrusconsists of Tangerines (Citrus × reticulata), Mandarins (Citrus × reticulata), Oranges (Citrus × sinensis), Grapefruits (Citrus maxima), Lemons (Citrus × limon), and other citrus fruits. This study investigated the effects of 74 different citrus species and harvesting time on the quality of citrus dark tea using Hubei green brick tea as the raw material. Oranges (Citrus × sinensis) were found to outperform other species in improving the quality of citrus dark tea. Additionally, the impact of orange harvesting time (August to December) on the quality of orange dark tea was investigated by using the Peach leaf orange with the highest sensory score as the subject of the study. Results revealed that harvesting time can considerably impact the flavor quality of orange dark tea, but not its infusion color or scent. Specifically, the orange dark tea processed with September-harvested Peach leaf orange exhibited a strong fruity scent, a sweet and smooth flavor, and a harmonious tea and fruit aroma. With the delay of harvesting time, a downtrend was observed in the content of soluble proteins, flavonoids, hesperidin, synephrine, and limonin, as well as total volatile components, with the largest decrease in synephrine and flavonoids. However, the polysaccharide content increased in the peel of Peach leaf orange. Functional analysis revealed that the delay of harvesting time can diminish the inhibitory capacity of orange-dark tea on α-glucosidase and α-amylase. Organoleptic quality and physiological activity analysis demonstrated September as the optimal time for harvesting Peach leaf oranges for processing orange dark tea.
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JOURNAL OF NANOBIOTECHNOLOGY
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2024
·Vol. 22
·期 1
·1-21
·
IF 10.6
Wu Zhen,Zhang Peng,Yue Jie,Wang Qingshan,Zhuang Peipei,Jehan Shah,Fan Liyuan,Xue Jiarun,Zhou Wenhu,Wang Haiyang
Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease, while there is a lack of pharmaceutical interventions to halt AAA progression presently. To address the multifaceted pathology of AAA, this work develops a novel multifunctional gene delivery system to simultaneously deliver two siRNAs targeting MMP-2 and MMP-9. The system (TPNs-siRNA), formed through the oxidative polymerization and self-assembly of epigallocatechin gallate (EGCG), efficiently encapsulates siRNAs during self-assembly. TPNs-siRNA safeguards siRNAs from biological degradation, facilitates intracellular siRNA transfection, promotes lysosomal escape, and releases siRNAs to silence MMP-2 and MMP-9. Additionally, TPNs, serving as a multi-bioactive material, mitigates oxidative stress and inflammation, fosters M1-to-M2 repolarization of macrophages, and inhibits cell calcification and apoptosis. In experiments with AAA mice, TPNs-siRNA accumulated and persisted in aneurysmal tissue after intravenous delivery, demonstrating that TPNs-siRNA can be significantly distributed in macrophages and VSMCs relevant to AAA pathogenesis. Leveraging the carrier’s intrinsic multi-bioactive properties, the targeted siRNA delivery by TPNs exhibits a synergistic effect for enhanced AAA therapy. Furthermore, TPNs-siRNA is gradually metabolized and excreted from the body, resulting in excellent biocompatibility. Consequently, TPNs emerges as a promising multi-bioactive nanotherapy and a targeted delivery nanocarrier for effective AAA therapy.Graphical Abstract
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Yi-Bin Li,Lei Xu,Sheng-Jie Han,Cai-Hua Liu,You Zhou,Ming-Lai Fu,Baoling Yuan
Solar-driven interfacial evaporation (SDIE) is considered to be one of the most promising strategies to solve the global freshwater shortage. However, the high cost of photothermal materials, the complex manufacturing process of evaporators, and low water evaporation rates and evaporation efficiency limit their practical application. In this study, a biochar-deduced porous hydrogel (TBC-PH) based on tea waste as a raw material was prepared as an efficient solar-driven interfacial evaporator using a simple cross-linking foaming method. The evaporator exhibits good light absorption, hydrophilicity and excellent salt resistance for efficient solar evaporation. Its interconnected porous structure enhances capillary action and enables rapid water transport while effectively preventing salt crystallization. Under one solar intensity, the water evaporation rate of 3.268 kg m −2 h −1 and the solar-to-vapor conversion efficiency of 95.14 % were achieved. Besides, TBC-PH exhibits obvious purification effect on seawater and organic dye wastewater. The evaporator’s utilization of waste biomass is not only simple and economical, but also advances the practical application of waste management while addressing water scarcity, highlighting its potential as an efficient and sustainable solution for SDIE applications.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Jianyu Huang,Jiahao Liao,Xiaoqiong Li,Hui Zhao,Hongxia Li,Jian Kuang,Jianqiang Li,Jinbin Guo,Tao Huang,Jinjun Li
In this study, in order to solve the application problems of poor water solubility and low bioavailability of quercetin, we prepared a nano-delivery system with core-shell structure by anti-solvent method, including a hydrophilic shell composed of tea saponin and a hydrophobic core composed of Zein, which was used to improve the delivery efficiency and biological activity of quercetin. Through the optimal experiments, the loading rate and encapsulation rate of nanoparticles reached 89.41 % and 7.94 % respectively. And the water solubility of quercetin is improved by 30.16 times. At the same time, the quercetin acted with Zein through non-covalent interaction and destroyed its spatial network through structural characterization, while tea saponin covered the surface of Zein through electrostatic interaction, making it change into amorphous state. In addition, the addition of tea saponin makes the nanoparticles remain stable under the changes of external environment. During simulating gastrointestinal digestion procedure, ZQTNPs has higher release rate and bioavailability than free quercetin. Importantly, ZQTNPs can overcome the limitations of a single substance through synergy. These results will promote the innovative development of quercetin precision nutrition delivery system.
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Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Zicheng Yang,Yuming Xie,Yi Feng,Jianfeng Yao
The effective utilization of biomass resources can bring significantly environmental and economic benefits. In this context, tea saponin, which can be easily and extensively extracted from the oil cake as the biomass waste during the seed oil production from camellia seeds, is explored as the precursor to synthesize porous carbon bearing abundant –OH and –COOH groups via a simple carbonization process. Owing to the obtained porous structure and existence of rich oxygen-containing groups serving as Lewis acidic sites, the carbonized tea saponin (CTS) can display impressive catalytic activities for CO 2 cycloaddition reaction with both high selectivity (> 99%) and high yield of target cyclic carbonate under either thermally driven (80 °C and 0.1 MPa CO 2 ) or photo-thermally driven (UV-Vis light irradiation with the light intensity of 350 mW/cm 2 ) conditions. In addition, benefiting from the good chemical stability, CTS can be reused for many cycles with almost no catalytic activity loss, making CTS a promising biomass-based catalyst for CO 2 fixation under mild conditions.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2024
·
IF 5.7
Yuqing Zhong,Chen Yang,Yongling Lu,Lishuang Lv
Acrolein (ACR), methylglyoxal (MGO), and glyoxal (GO) are a class of reactive carbonyl species (RCS), which play a crucial role in the pathogenesis of chronic and age-related diseases. Here, we explored a new RCS inhibitor (theanine, THE) and investigated its capture capacity on RCS in vivo by human experiments. After proving that theanine could efficiently capture ACR instead of MGO/GO by forming adducts under simulated physiological conditions, we further detected the ACR/MGO/GO adducts of theanine in the human urine samples after consumption of theanine capsules (200 and 400 mg) or green tea (4 cups, containing 200 mg of theanine) by using ultraperformance liquid chromatography–time-of-flight–high-resolution mass spectrometry. Quantitative assays revealed that THE-ACR, THE-2ACR-1, THE-MGO, and THE-GO were formed in a dose-dependent manner in the theanine capsule groups; the maximum value of the adducts of theanine was also tested. Furthermore, besides the RCS adducts of theanine, the RCS adducts of catechins could also be detected in the drinking tea group. Whereas, metabolite profile analysis showed that theanine could better capture RCS produced in the renal metabolic pathway than catechins. Our findings indicated that theanine could reduce RCS in the body in two ways: as a pure component or contained in tea leaves.
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JOURNAL OF FOOD COMPOSITION AND ANALYSIS
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2024
·
IF 4
Dongjian Li,Mulinde Timothy Ezra,Haoran Li,Yifei Chen,Chengyun Si,Xuefang Luo
Neonicotinoids (NEOs) are widely used in agricultural cultivation, and the presence of residual NEOs poses a serious threat to consumer health. Therefore, trace detection of NEOs is particularly important. In this study, a response surface experimental design was employed to develop AgNP with high enhancement factor and surface height anisotropy, effectively enhancing the Raman signals of acetamiprid (ACE) and thiacloprid (THI) through densely populated hotspots on the surface. Gaussian simulation calculations were used to assign peaks in the ACE and THI spectra. Subsequently, convolutional neural network, backpropagation neural network, and AlexNet neural network were employed to identify the ACE, THI, and mixed component spectra, successfully distinguishing the spectra of the three compounds and achieving qualitative analysis of unknown spectra. Furthermore, genetic algorithm-partial least squares was used to model the spectral data, achieving a correlation coefficient of 0.97. The method was applied for the detection of spiked tea samples, achieving a precision RSD of 4.84 %. Therefore, this sensor combined with intelligent algorithms can be used for spectral identification and trace detection of mixed pesticide samples with structurally similar compounds.
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MOLECULES
·
2022
·Vol. 27
·期 17
·5677
·
IF 4.927
Jiachun Lu,Yanyan Cao,Yani Pan,Sifan Mei,Gang Zhang,Qiang Chu,Ping Chen
The chemical substances responsible for thekokumitaste of green tea infusion are still unclear. Here, we isolated thekokumicompound-containing fractions from green tea infusion through ultrafiltration, and the majorkokumicompounds were characterized as γ-Glu-Gln and γ-Glu-Cys-Gly (GSH) through ultra-high-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS). The results indicated that peptides and amino acids were essential compounds in the kokumi-enriched fractions for conducting the sense ofkokumi. L-theanine had an enhancing effect on thekokumitaste of green tea infusion, which was confirmed in the sensory reconstitution study. Thus, peptides, especially γ-Glu-Gln and GSH, are the majorkokumicompounds in green tea infusion, which has the potential of improving the flavor of tea beverages.Keywords:kokumipeptides;sensory-guided;identification;characterization;recombination
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2022
·
IF 5.895
Yi Wang,Xinlei Xu,Jianle Chen,Xingqian Ye,Haibo Pan,Shiguo Chen
A novel protocol was established to synthesize novel α-glucosidase inhibitors (prodelphinidin B gallates) from proanthocyanidins from Chinese bayberry leaves (BLPs) and epigallocatechin gallate (EGCG) via acid-catalyzed transformation, which had improved regulation against postprandial hyperglycemia. Their structural–activity relationship was clarified by enzymatic kinetics, multispectroscopic method, molecular docking analysis, and sucrose loading test. ProDB MG and DG were noncompetitive inhibitors of α-glucosidase with IC50 values of 7.82 and 7.52 μg/mL, respectively. They bound with α-glucosidase spontaneously through van der Waals force and hydrogen bonding interaction, inducing the change of spatial conformation and secondary structure of α-glucosidase. Molecular docking studies suggested that proDB MG and DG attached to another one nonactive pocket with strong affinity. ProDB DG exerted significant improvement of postprandial hyperglycemia in a dose-dependent manner. Hence, proDB MG and DG, potential antidiabetic compounds, alleviate postprandial hyperglycemia by inhibiting α-glucosidase.
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ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
·
2020
·
IF 3.391
Lin Yin,Shanshan Fu,Roujun Wu,Shuyue Wei,Juzhen Yi,Li-Ming Zhang,Liqun Yang
A neutral tea polysaccharide (TPSN) was isolated from green tea. Gas chromatography analysis showed that TPSN was composed of d -glucose, l -arabinose and d -galactose residues at a molar ratio of 90.0: 9.1: 0.9. The weight-averaged molecular weight of TPSN was determined as about 2.0 × 10 5 g mol −1 using static light scattering analysis. The result of nuclear magnetic resonance (NMR) spectroscopy indicated that TPSN and water-soluble starch had similar structures. TPSN exhibited inhibitory activity towards α-amylase through the noncompetitive inhibition mechanism, but the tertiary structure of α-amylase related to enzymatic activity , analyzed using circular dichroism spectroscopy, was not affected by TPSN. Meanwhile, TPSN exhibited hydrolysis properties catalyzed by α-amylase. Molecular docking analysis revealed that the various behaviors of TPSN to α-amylase could be attributed to that the different chain segments of TPSN combined with different amino acid residues of α-amylase.
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FOOD CHEMISTRY
·
2023
·
IF 8.8
Zuo-Qin Liang,Dong-Dong Song,Zhuo-Cheng Li,Su-Hang Xu,Guo-Liang Dai,Chang-Qing Ye,Xiao-Mei Wang,Xu-Tang Tao
Photoactivatable probes can switch fluorescence on from a weak or nonemission state to improve the sensitivity of the sensing system. In this work, we successfully constructed three highly emissive photoactivatable probes, 2-DP, 1-2-DP and 2-2-DP, for Cu 2+ detection. Under UV irradiation, the photoluminescence quantum yields of 2-DP, 1-2-DP and 2-2-DP display approximately 52.4-, 11.5- and 49.2-fold enhancement, respectively. Cu 2+ selectively quenches the bright photoactivated fluorescence, resulting in an approximately 38-fold fluorescence reduction. The highly selective fluorescence response to Cu 2+ yields an excellent low detection limit of 5.8 nM. Moreover, the photoactivatable probes were successfully applied for Cu 2+ determination in tap water and tea samples with recovery ranges of 95%–105% and 97%–106%, respectively. This work provides a more sensitive and efficient methodology for Cu 2+ detection in heavy metal pollution and food safety.
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