MICROPOROUS AND MESOPOROUS MATERIALS
·
2020
·
IF 4.551
Niu Liu,Jun Cheng,Wen Hou,Xiao Yang,Junhu Zhou
In order to form strengthened active sites for superior CO 2 adsorption on core shell ZIF-8@ZIF-67 nanocomposites , graphene oxide (GO) with oxygen-containing functional groups was used as support to synthesize hybrid adsorbents with unsaturated Zn–N 2 –O active sites. The results of XPS O 1s and FTIR analysis revealed that the Me–O functional group content in the 0.5 wt% graphene oxide (GO)-supported core shell ZIF-8@ZIF-67 nanocomposite (38.9 at.%) was much higher than that in the 0.5 wt% reduced graphene oxide (RGO)-supported nanocomposite (19.4 at.%). This was because hydroxyl functional groups in the GO formed coordination bonds with zinc atoms in core shell ZIF-8@ZIF-67. XPS N 1s spectra indicated that the incorporation of oxygen-containing functional groups in GO resulted in the transition of binding form from Me–N 4 to Me–N 2 . The CO 2 adsorption capacity of GO-supported core shell ZIF-8@ZIF-67 gradually decreased from 2.15 to 1.30 mmol/g as GO weight percentage increased from 0.5 to 4 wt%, which was consistent with the decrease in BET surface area from 1378 to 585 m 2 /g and increase in peak pore diameter from 7.7 to 8.2 Å. Density functional theory (DFT) calculations demonstrated that unsaturated Zn–N 2 –O active sites in GO-supported core shell ZIF-8@ZIF-67 nanocomposites resulted in a decreased O C⋯Zn interaction distance from 4.65 (Zn–N 4 sites in core shell ZIF-8@ZIF-67) to 3.46 Å and an increased binding energy from 34.02 to 38.87 kJ/mol. Therefore, 0.5 wt% GO-supported core shell ZIF-8@ZIF-67 nanocomposites exhibited the highest CO 2 adsorption capacity of 2.15 mmol/g (at 273 K and 1 bar), 1.34 times higher than that of core-shell ZIF-8@ZIF-67.
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高影响因子
ANALYTICA CHIMICA ACTA
·
2021
·
IF 6.558
Ning Wu,Hao Guo,Mingyue Wang,Yujuan Cao,Lei Sun,Fan Yang,Tingting Zhang,Liping Peng,Yinsheng Liu,Wu Yang
Metal-organic frameworks (MOFs) can perform later transformation without compromising the integrity of the overall framework, and a variety of chemical reactions can be used to modify framework components. Postsynthetic modification (PSM) of MOFs has been developed as an alternative strategy that can expand the range of MOF functional groups. Considering the p-type semiconducting visible light active performance of CuBi 2 O 4 (CBO) and the unique porous nanostructure and stability of zeolitic imidazolate framework-8 (ZIF-8), in this work, a novel core-shell coordination assembled hybrid based on p-type semiconductor@MOFs (Eu-CBO@ZIF-8) is prepared for the first time via in-situ growth and postsynthetic metal exchange. A series of detailed characterizations were conducted to confirm the successful synthesis of the material. Moreover, we are focusing on using this material as a new dual-functional sensing material for simultaneous detection and removal of tetracycline (TC), which shows an outstanding analytical performance with a low detection limit of 17 nM, relatively broad linear range (0–70 μM), fast response of less than 120 s, and excellent adsorption performance (377.07 mg g −1 ) toward TC. In addition, the sensitive luminescence response caused by TC makes Eu-CBO@ZIF-8 undergo a significant color transition from dark to red under UV-lamps, which is beneficial for visual analysis with the naked eye. The possible detection and adsorption mechanisms, including coordination between Eu 3+ and the detected substance, the hydrogen bond between ligand and the detected substance, were further discussed. In addition, the practical feasibility of Eu-CBO@ZIF-8 for TC sensing was also studied, with a satisfactory recovery rate of 96.9%–104.6% and RSD ≤3.32%. These results indicate that this material can be used for the detection and adsorption of TC in actual samples.
研究领域:
材料科学
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环境科学
·
分析化学
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DOI
高影响因子
Nanoscale
·
2020
·Vol. 12
·期 24
·12779-12789
·
IF 6.895
Yi Cao,Zhenqi Jiang,Yanying Li,Yinjie Wang,Yong Yang,Ozioma Udochukwu Akakuru,Juan Li,Aiguo Wu
Zeolitic imidazolate frameworks (ZIFs) as emerging porous materials have attracted remarkable attention for their unprecedented porosity and acidic sensitive degradation that enables high drug loading and microenvironment responsive fast payload release. However, the limited functions and disadvantages of ZIFs such as early drug release, potential cytotoxicity inducing damage to major organs, and even death of animals, impede their further biomedical application. In this work, we report the first tandem post-synthetic modification of ZIF-7 with both metal ions and organic ligands. Inspired by the benzimidazole-like inhibitors that are similar to the organic ligand of ZIF-7, a chemokine (C-X-C motif) receptor 4 (CXCR4) inhibitor AMD-070 (AMD) and magnesium ions (Mn2+) were successfully tandem exchanged to the ZIF-7 framework, forming an active-targeting framework AMD-ZIF-7(Mn) for CXCR4-overexpressed esophageal squamous cell cancer. The obtained AMD-ZIF-7(Mn) showed good biocompatibility in vitro and in vivo. Meanwhile, it exhibited an excellent T1-weighted magnetic resonance imaging performance and CXCR4 targeting ability. With 5-Fu loading, AMD-ZIF-7(Mn)/5-Fu showed a synergistic therapeutic effect in DNA damage and CXCR4 inhibition of esophageal squamous cell cancer. Therefore, we propose a structural reconstruction method to effectively explore and improve the biomedical application of ZIFs in esophageal squamous cell cancer theranostics.
研究领域:
生物材料学
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癌症治疗学
·
医学影像学
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DOI
PubMed
高影响因子
INORGANIC CHEMISTRY
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2022
·
IF 5.436
Yingwu Zhou,Yujie Ban,Weishen Yang
Reversible phase transformations (RPTs) of metal–organic frameworks not only create material diversity but also promise a self-restoration of crystals in a controllable manner. However, there are only limited examples because seeking for a convenient and effective trigger for RPTs, especially for RPTs with respect to spatiotemporal harmony in cleavage and reconstruction of metal–linker chemical bonds, is challenging. In this work, we found that zeolitic imidazolate framework (ZIF)-108 with Zn–N coordination bonds showing moderate strength was an ideal platform. We reported three crystal phases of ZIF-108, namely, sodalite (SOD), diamondoid (DIA), and large pore_sodalite (lp_SOD) topologies, and identified RPTs between phases: (1) when exposed to water or water vapor, the SOD structure could transform to a compact DIA version as a result of the decomposition of four-membered rings and synchronous reorganization of six-membered rings. Then, the DIA structure could also return back to SOD when soaked in dimethylformamide (DMF) or DMF vapor. (2) High-temperature treatment of SOD gives rise to lp_SOD, which then reverts to SOD by DMF. (3) lp_SOD could also be compressed into the DIA phase by water or water vapor and can then be restored via a two-step treatment, namely, soaking in DMF (DIA → SOD) right before a high-temperature therapy (SOD → lp_SOD). From the perspective of the separation utility, we found that the lp_SOD version of ZIF-108, relative to SOD-structured ZIF-108, can produce mixed matrix membranes having an interesting interfacial structure with the polymer chains, though both share the same chemical composition. We verified that the large pore of lp_SOD can allow being penetrated by polymer chains, which contributed to not only reinforcing the bi-phase interface but also sharpening the molecule sieve properties of fillers toward CO2 and CH4.
研究领域:
材料科学
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化学工程
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DOI
PubMed
高影响因子
INDUSTRIAL CROPS AND PRODUCTS
·
2025
·
IF 6.2
Dujuan Wu,Ruiqi Xin,Lingling Hu,Onder Tor,Ye Song,Song Li,Meiling Chen,Wenkai Zhu
Indoor air pollution presents a significant challenge to human health, driving the development of advanced materials for indoor environmental remediation. Metal–organic frameworks (MOFs) derived materials possess great promise as promising candidates for addressing this challenge. In this work, the delignified bamboo with multi-scale structure was employed as a substrate to fabricate ZIF-8@bamboo by in-situ and ex-situ growth strategies. The results demonstrated that the delignified bamboo exposed polysaccharided cellulose active group originally present in the bamboo cell walls. The pretreated bamboo was facilitated to the uniform growth of ZIF-8 crystals, and the loaded ZIF-8 exhibited high crystallinity and well-distributed morphological characteristics. Moreover, the successful growth of ZIF-8 increased the bamboo’s specific surface area. Additionally, the formaldehyde adsorption tests revealed that the ZIF-8@bamboo exhibited a 227.73 % improvement for formaldehyde adsorption rate at room temperature. Meanwhile, it also showed a rapid adsorption rate, high adsorption capacity, and reusable performance for formaldehyde. Furthermore, the as-prepared ZIF-8@bamboo demonstrated high removal efficacy for other indoor pollutants, including PM2.5 and PM10. Moreover, the ZIF-8@bamboo exhibited high indoor pollutant removal efficiency after five repeated cycles. Therefore, the ZIF-8@bamboo proposed in this work provides an effective solution to address indoor environmental pollution.
研究领域:
材料科学
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环境科学
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室内环境治理
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DOI
高影响因子
Nanoscale
·
2018
·Vol. 10
·期 24
·11384-11391
·
IF 7.233
Linlin Wang,Hongli Zhu,Ying Shi,You Ge,Xiaomiao Feng,Ruiqing Liu,Yi Li,Yanwen Ma,Lianhui Wang
Micromotors hold promise as drug carriers for targeted drug delivery owing to the characteristics of self-propulsion and directional navigation. However, several defects still exist, including high cost, short movement life, low drug loading and slow release rate. Herein, a novel catalytic micromotor based on porous zeolitic imidazolate framework-67 (ZIF-67) synthesized by a greatly simplified wet chemical method assisted with ultrasonication is described as an efficient anticancer drug carrier. These porous micromotors display effective autonomous motion in hydrogen peroxide and long durable movement life of up to 90 min. Moreover, the multifunctional micromotor ZIF-67/Fe3O4/DOX exhibits excellent performance in precise drug delivery under external magnetic field with high drug loading capacity of fluorescent anticancer drug DOX up to 682 μg mg−1 owing to its porous nature, high surface area and rapid drug release based on dual stimulus of catalytic reaction and solvent effects. Therefore, these porous ZIF-67-based catalytic micromotors combine the domains of metal–organic frameworks (MOFs) and micomotors, thus developing potential resources for micromotors and holding great potential as label-free and precisely controlled high-quality candidates of drug delivery systems for biomedical applications.
研究领域:
生物医学工程
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纳米医学
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材料科学
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DOI
高影响因子
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
·
2025
·Vol. 113
·期 6
·e37937
·
IF 3.9
Yiyang Xu,Ying Li,Zixuan Ye,Cheng Wang,Pengfei Cui,Shuwen Zhou,Lin Qiu,Jianhao Wang
Wound bacterial infection deteriorates with antibiotic misuse, boosting bacterial drug resistance, threatening human health. Therefore, combining natural antibacterials with efficient broad-spectrum materials offers new solutions. Artemisia argyi is a kind of medicinal plant distributed in Asia, known for its rich biological active compounds. With the advancement of modern analytical technology, Artemisia argyi has shown excellent antibacterial and anti-inflammatory potential, particularly Artemisia argyi essential oil (AAEO) which is considered to be the most active substance in Artemisia argyi. However, its practical application is limited due to its poor water solubility, strong volatility, high sensitivity to light and heat, and its irritating odor. Zeolitic imidazolate framework-8 (ZIF-8) is a type of metal–organic framework material (MOF) with good biocompatibility, simple synthesis, high porosity, and antimicrobial activity. ZIF-8 can be used as an ideal vehicle for the preparation of antibacterial materials. In this study, we loaded AAEO onto ZIF-8 to successfully develop AAEO@ZIF-8 antibacterial nanomaterial. The bactericidal ability and antibacterial mechanism of AAEO@ZIF-8 were evaluated through in vitro experiments such as bacterial coating, Live/Dead staining, and crystal violet staining. It was confirmed that AAEO@ZIF-8 had significant antibacterial activity against both Staphylococcus aureus and Escherichia coli . In in vivo experiments, the wound model using C57BL/6 male mice was established, and wound tissue staining with Gram, CD31 + immunohistochemistry, H&E, and Masson staining was performed to evaluate the antibacterial activity of AAEO@ZIF-8. The results showed that AAEO@ZIF-8 exhibited the best wound repair performance in the model. These findings suggested that AAEO@ZIF-8 is a novel and effective antimicrobial nanomaterial targeting pathogenic bacteria. This study successfully transformed the storage mode of AAEO from liquid to solid, providing a promising strategy for the application of AAEO in the treatment of wound bacterial infections.
研究领域:
药理学
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生物材料科学
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微生物学
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DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Hongxu Tao,Haiqian Lian,Jingxian Hua,Shengui Ju,Yichang Pan
The MOF membrane has shown great promise for the gases or organic solvent mixtures separation. However, the implementation of MOF membranes remains challenged by defect formation during membrane fabrication. Herein, we reveal that the activation solvent plays a critical role in governing the degree of defect and separation performance in secondary-growth-derived ZIF-8 membranes. The isopropanol activation process exerts excellent membrane structure protection through a synergistic dual mechanism to limit the generation of ZIF-8 membrane defects during drying: (a) The isopropanol inhibits the ZIF-8 seed layer recrystallization and maintains its porous architecture to mitigate interfacial stress during drying through its elastic deformation. (b) The low surface tension of isopropanol minimizes the capillary force during solvent removal to reduce the risk of structural damage. While methanol activation and n-propanol activation have no such structure control. The optimized isopropanol-activated membrane achieves a C 3 H 6 /C 3 H 8 selectivity of 141 to show a 4.8-fold and a 4.4-fold compared to n-propanol- and methanol-activated membranes at room temperature and 1 bar. This study highlights low-surface-tension as an effective strategy for defect suppression in MOF membranes, advancing their potential for industrial hydrocarbon separations.
研究领域:
材料科学
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化学工程
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产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Nijuan Liu,Yuanzhuo Li,Nana Wang,Fupeng Jin,Duoqiang Wang,Ruijuan Wang,Hongping Zhang,Hao Liang,Ruibin Guo,Wei Tian,Zunli Mo
The extraction of uranium from seawater is crucial for the advancement of sustainable energy development, driving urgent demands for high-performance adsorbents. Herein, a composite adsorbent was engineered based on MXene nanosheets. To address the self-stacking issue of the nanosheets, polyacrylamide (PAM) was intercalated as a molecular spacer, which was followed by the in situ growth of zeolitic imidazolate framework-8 (ZIF-8) on the modified MXene nanosheet surface. The material exhibited a hierarchical pore structure and high specific surface area (604 m2/g), facilitating active site exposure. Maximum uranium adsorption capacity reached 909 mg/g at pH 4.0 and 298 K, with high selectivity. Adsorption kinetics conformed to a pseudo-second-order model, isotherms aligned with the Temkin model, and thermodynamics revealed a spontaneous, endothermic process. FT-IR and XPS spectroscopy confirmed the UO22+ coordination with MXene (Ti–O, –COOH), PAM (–NH2), and ZIF-8 (pyrrole-N, Zn–O). The material maintained stable performance in complex aqueous environments, exhibiting uranium adsorption capacities of 33, 34, and 37 mg/g in spiked salt lake water, seawater, and Yellow River water systems, respectively. This work has provided valuable insights for designing MXene-based adsorbents for uranium extraction from natural water.
研究领域:
材料科学
·
环境工程
·
核能
·
吸附技术
·
纳米材料
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产品关联
DOI
高影响因子
ACS Biomaterials Science & Engineering
·
2020
·
IF 4.152
Lingxia Shi,Jun Wu,Xinrui Qiao,Yuan Ha,Yunpeng Li,Cheng Peng,Renbing Wu
The exploration of metal–organic frameworks (MOFs) with good biocompatibility and physiological stability as carrier platforms for biomedical applications is of great importance but remains challenging. Herein, we developed an in situ biomimetic mineralization strategy on zeolitic imidazolate framework (ZIF) nanocrystals to construct a drug release system with favorable cytocompatibility, improved stability, and pH responsiveness. With lysozyme (Lys) wrapped on the surface of Zn-based ZIF (ZIF-8), Lys/ZIF-8 could strongly bond metal ions to promote nucleation and growth of bone-like hydroxyapatite (HAp), leading to formation of HAp@Lys/ZIF-8 composites. In vitro investigations indicate that the composites with a hollow Lys/ZIF-8 core and a HAp shell exhibited a high drug-loading efficiency (56.5%), smart pH-responsive drug delivery, cytocompatibility, and stability under physiological conditions. The proposed biomimetic mineralization strategy for designing MOFs-based composites may open a new avenue to construct advanced delivery systems in the biomedical field.
研究领域:
生物医学工程
·
材料科学
·
药学
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DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2015
·
IF 3.091
Lin Zhang,Gang Qian,Zongjian Liu,Qun Cui,Haiyan Wang,Huqing Yao
Adsorption equilibrium and kinetic data is essential for the design of an adsorption process. In this work, the adsorption isotherms of n-pentane/isopentane on zeolitic imidazolate framework material (ZIF-8) were measured at 308, 343 and 373 K over the pressure range from 0 to 9.7 kPa by a gravimetric system. The equilibrium adsorption capacity at 303 K and 9.7 kPa is 0.2504 g g −1 for n-pentane and 0.1439 g g −1 for isopentane. Langmuir model was used to fit the adsorption isotherms. The adsorption kinetics of n-pentane/isopentane was studied at 308 K in the pressure range from 0 to 69.9 kPa. The data was well fitted with linear driving force model (LDF) model. The adsorption rate constant of n-pentane is from 0.0019 to 0.0326 s −1 , which is higher than that of isopentane, represented 0.0007–0.0036 s −1 . The adsorption selectivity of n-pentane/isopentane on ZIF-8 was contrast by the measurement of the binary breakthrough experiments at 343 K, 363 K and 393 K in the partial pressure of 7 kPa. When the adsorption temperature is 363 K, the adsorption selectivity of n-pentane/isopentane on ZIF-8 reaches the maximum 55. Compared with 5A molecular sieve, the desorption temperature of n-pentane on ZIF-8 was analyzed by temperature-programmed-desorption (TPD) method. The peak temperature of n-pentane desorption on ZIF-8 is 361 K. However are 392 K and 443 K on a 5A molecular sieve. Thus, ZIF-8 is more selective or preferential adsorption for n-pentane in comparison to isopentane molecules at low temperature.
研究领域:
吸附科学
·
分离技术
·
多孔材料
·
化学工程
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DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2026
·
IF 10.6
Fengzhen Yang,Meixuan Li,Kaiyuan Jia,Qiang Zhang,Chaoyuan Wang,Yuhe Wang,Jianmin Zhang,Jianhan Lin,Lei Wang
Bacterial aerosols, a major infectious disease transmission route, require effective capture, inactivation, and detection. Most air filters provide high-efficiency filtration but lack efficient target recovery and rarely integrate inactivation with downstream analysis. Herein, a monolithic ZIF-8-based foam coupled with a nanozyme-assisted colorimetric biosensor was developed for bacterial aerosol sampling, recovery, and detection. A polysaccharide ZIF-8-based foam (PC-ZIF-8 foam) was used to efficiently capture and concentrate airborne bacteria. The foam was then dissolved in phosphate-buffered saline (PBS) to release the captured bacteria, thereby enabling direct downstream analysis. Meanwhile, zinc ions (Zn 2 + ) released during dissolution contributed to bacterial inactivation, which enhanced biosafety during subsequent sample handling. Besides, a colorimetric biosensor based on Fe-ZIF-8 nanozymes was used for detection of the captured bacteria. This system achieved high performance: > 99.95% capture efficiency for 0.3–1 μm bacterial aerosols at 4 L/min while only causing low pressure drops (<35 Pa), > 99.99% bacterial inactivation within 15 min, and a low detection limit of 117 CFU/m 3 in 90 min. This work provided a practical platform for integrated bacterial aerosol sampling and detection with improved recovery and operational safety.
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DOI
PubMed
高影响因子
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