INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Jinnan Guo,Yuanyuan Zhao,Guanqun Peng,Tong Ye,Xiaohui Zhu,Runtian Li,Jintao Shen,Lina Du,Shanshan Wang,Zhiyun Meng,Hui Gan,Ruolan Gu,Wenzhong Sun,Guifang Dou,Shuchen Liu,Yunbo Sun
Severe bleeding from deep and irregular wounds poses a significant challenge in prehospital and surgical settings. To address this issue, we developed a novel chitosan-based hemostatic dressing with a magnetic targeting mechanism using Fe 3 O 4 , termed bovine serum albumin-modified Fe 3 O 4 embedded in porous α-ketoglutaric acid/chitosan (BSA/Fe 3 O 4 @KA/CS). This dressing enhances hemostasis by magnetically guiding the agent to the wound site. In vitro, the hemostatic efficacy of BSA/Fe 3 O 4 @KA/CS is comparable to that of commercial chitosan (Celox™) and is not diminished by the modification. In vivo, BSA/Fe 3 O 4 @KA/CS demonstrated superior hemostatic performance and reduced blood loss compared to Celox™. The hemostatic mechanism of BSA/Fe 3 O 4 @KA/CS includes the concentration of solid blood components through water absorption, adherence to blood cells, and activation of the endogenous coagulation pathway. Magnetic field targeting is crucial in directing the dressing to deep hemorrhagic sites. Additionally, safety assessments have confirmed the biocompatibility and biodegradability of BSA/Fe 3 O 4 @KA/CS. In conclusion, we introduce a novel approach to modify chitosan using magnetic guidance for effective hemostasis, positioning BSA/Fe 3 O 4 @KA/CS as a promising candidate for managing various wounds.
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PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Jingxuan Zhao,Hongxu Liu,Yuchao Qi,Ruijia Wang,Ziwei Lv,Yang Yu,Shulin Sun,Yiming Wang
In this work CS-SDAEM polymer brushes with long-chain structure were synthesized, and TiO 2 /CS-SDAEM nanoparticles were prepared by modifying them on the TiO 2 surface. The prepared modified membrane can effectively degrade dyes through photocatalysis and can reduce the contamination rate of the membrane during use. The separation membrane achieves efficient removal of contamination by self-cleaning. The results of the membrane surface analysis test show that the formation of coordination bonds between o-benzenetriol of GA and TiO 2 , and the chemical reaction between CS and GA, which promote the stability between coating components. The results of filtering tests show that with the excellent anti-fouling performance of long-chain polymer brush, the photodegradability of TiO 2 and a large number of hydrophilic groups contained in GA and CS, PVDF- TiO 2 /CS-SDAEM membranes overcome the above shortcomings and achieve super-hydrophilicity, anti-fouling and self-cleaning. In addition, DFT model simulations of photocatalytic processes show that there is a charge transfer between CS and TiO 2 , which increases the width of the high light absorption band and improves the efficiency of photodegradation. Modified membranes achieve efficient self-cleaning processes and low flux decline rates, which hold great promise for use in real wastewater application scenarios.
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高影响因子
INORGANIC CHEMISTRY
·
2024
·
IF 4.3
Mengmeng Zhu,Junbo Wang,Lei Hou,Yiwen Yuan,Lili Liu,Yaoqing Chu,Chunmei Huang
The design and syntheses of new birefringent crystals will be of great importance in commercial applications and materials science. A series of ultraviolet (UV) birefringent crystals, AX·(H2SeO3)n (A = K, Cs; X = Cl, Br; n = 1, 2), with large sizes up to 23 × 6 × 3 mm3, was successfully synthesized by simple aqueous solution method. These four compounds belong to three different space groups. Isomorphic KCl·(H2SeO3)2 and CsCl·(H2SeO3)2 crystallize in the P1¯ space group, while CsBr·(H2SeO3)2 and CsCl·H2SeO3 crystallize in the P21/m and P21/c space groups, respectively. They exhibit cocrystal structures composed of [2(H2SeO3)]∞ and [AX]∞ frameworks, ingeniously inheriting the large optical anisotropy of selenite and the wide band gap of alkali metal halide. And it proves that these compounds indeed possess large birefringence (0.1–0.17 at 532 nm) and short UV cutoff edges (227–239 nm), achieving a balance of optical properties. This research affords a simple and viable strategy for the design and syntheses of new UV birefringent crystals. Besides, it is also found that the n value and ionic size (A and X ions) have important influences on the crystal structures and optical properties of AX·(H2SeO3)n. And this will promote further understanding of the alkali metal halide selenite family.
研究领域:
材料科学
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晶体工程
·
光学材料
·
无机化学
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高影响因子
Small Methods
·
2025
·
IF 9.1
Yaping Wang,Tingshi Zhang,Xinlian Huang,Yurong Zeng,Siyuan Wei,Zanyong Zhuang,Chongbing Zhu,Yan Yu
Herein, a versatile amorphous-to-crystalline transformation (ACT) strategy is described, to furnish various metals (Cu, Co, Ni, Cs, and Y) based atomically dispersed catalysts (ADCs) on thin holey 2D Al 2 O 3 . This approach, which involves adjusting reactant stoichiometry, enables the continuous modulation of particle size of ADCs at an atomical level, giving the ultrafine products as single atom, cluster, or nanoparticle catalysts. This synthesis method allows a straightforward analysis and comparison of the reactivity of the ADCs catalysts based on the dispersion of the active metal. In the case of Cu, the cluster catalyst 0.2-Cu/Al 2 O 3 outperforms the single atom catalyst 0.1-Cu/Al 2 O 3 and the nanoparticle catalyst 0.3-Cu/Al 2 O 3 in the oxidation of refractory organic molecules, thanks to its superior electron transport and surface adsorption properties. These findings are well supported by the Density functional theory (DFT) calculations. Additionally, this method facilitates the preparation of atomic clusters with a very small size of 0.5–1 nm, composed of just a few atoms, as exemplified by Ni-based ADCs. The developed synthesis enriches the library of ADCs and demonstrates the potential of amorphous-to-crystalline transformation in creating advanced ultrasmall functional materials.
研究领域:
材料科学
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催化化学
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理论计算
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高影响因子
JOURNAL OF ANALYTICAL CHEMISTRY
·
2026
·
IF 1.5
Sha Ou,Wu Yunfan,Xu Yuan,Yao Yang,Zhang Kaixuan,Fan Guangyu
In this study, an eco-friendly and dependable method based on magnetic solid-phase extraction and high-performance liquid chromatography equipped with ultraviolet detection was established to extract and determine chlorpromazine in milk. A novel composite material, Fe 3 O 4 @CS@AC, used as a magnetic adsorbent, was successfully synthesized via the chemical co-precipitation method and characterized. Various factors influencing the recovery of chlorpromazine were discussed and optimized. Moreover, Fe 3 O 4 @CS@AC for chlorpromazine exhibits a large adsorption capacity of 17.82 mg/g, and its mass transfer mechanism aligns more closely with the quasi-second-order kinetic model, dominated by chemisorption. Under optimal conditions, the linearity of chlorpromazine was investigated in the range of 0.01–5.00 mg/L, with a coefficient of determination greater than 0.9995, and the limit of detection was 2.47 × 10 –3 mg/L. The feasibility of the developed method was evaluated by analyzing and detecting chlorpromazine in different milk samples, with recoveries of 90.76–96.72% and relative standard deviation of 2.01–4.23%. This method, with straightforward operation and good reproducibility, was successfully applied for the analysis and determination of trace chlorpromazine in milk, providing a promising avenue for the development and application of novel adsorbents in milk analysis.
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高影响因子
HYDROMETALLURGY
·
2025
·
IF 5.3
Yanfei Fan,Dandan Gao,Dongdong Li,Dewen Zeng
Alum is an important intermediate for the extraction and purification of Cs or Rb chemicals, due to its excellent separation ability for Cs, Rb and K. Although the solubility sequence K-alum > Rb-alum > Cs-alum has been well known, the separation factors among Cs, Rb and K during the formation of alum have not been determined. The formation of solid solution of alum controls the Cs or Rb content and Cs/Rb/K ratio in the sequentially precipitated Cs, Rb and K alums. In this study, the thermodynamic equilibrium separation factors were determined from the solid solution-aqueous solution equilibrium data of the two mixed alum systems: (i) RbAl(SO 4 ) 2 , CsAl(SO 4 ) 2 , and H 2 O, and (ii) KAl(SO 4 ) 2 , RbAl(SO 4 ) 2 and H 2 O. The separation factor β Cs/Rb varied from 48 to 2 with the increase of the Rb/Cs ratio in system (i), and β Rb/K varied from 22 to 0.2 with the increase of the K/Rb ratio in system (ii). This suggests that the purification of Cs or Rb using alums is more efficient from raw materials containing high Cs/Rb or Rb/K ratio than that from low Cs/Rb or Rb/K ratio. In kinetic studies, the apparent separation factors β Cs/Rb and β Rb/K were highly affected by the recrystallization process of cooling or non-cooling and the initial composition of raw alum, showing asymmetric kinetic intensification. The separation factors β Cs/Rb or β Rb/K obtained in the “dissolution by heating and crystallization by cooling (DHCC)” process for the raw alum with high initial Cs/Rb or Rb/K molar ratio is several times larger than the equilibrium value expected from thermodynamics. Finally, CsAl(SO 4 ) 2 and RbAl(SO 4 ) 2 with a metal-based purity of 99.97 % and 99.94 %, respectively, were obtained by using the DHCC process 3–4 times.
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高影响因子
MICROCHEMICAL JOURNAL
·
2022
·
IF 5.304
Mansoor Khan,Mustafa Soylak
Palladium is an important metal as it has a wide range of applications in different fields but can cause cancer in human beings. Therefore, precise quantification of palladium is important. For this purpose, new material Ti 3 AlC 2 max phase having unique properties like high stability, thermal conductivity and environmental friendly has been synthesized. To increase its surface area of Ti 3 AlC 2 max phase, graphene oxide (GO) has been incorporated to form Ti 3 AlC 2 max phase GO nanocomposite. Ti 3 AlC 2 max phase GO nanocomposite was used as solid phase extracting material for microextraction and preconcentration of Pd(II) in environmental samples and medical appliances. Characterization of the adsorbent was achieved by using fourier transform infrared spectroscopy (FT-IR), scanning electron microscope (SEM), X-ray diffraction (XRD), energy dispersive X-ray (EDX) and surface area analyzer (SAA). All the parameters that influence the extraction efficiency of the adsorbent like solution pH, amount of adsorbent, volume of sample, vortex time, desorption condition and interferences effect were determined and optimized. The limit of detection (0.327 µg/L) and limit of quantification (1.09 µg/L) show that the method is highly sensitive. The relative standard deviation was calculated as 5.48 % for five repeated measurements, which shows that the developed method is reproducible. The method is highly efficient with large values of preconcentration factor (20) and enhancement factors (20). The method was validated by applying the method to real water samples, soil samples and medical appliances with satisfied recovery results (94–106 %).
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Small
·
2022
·Vol. 18
·期 12
·2106083
·
IF 15.153
Yu Gao,Wenzhan Xu,Si-Wei Zhang,Tianjie Fan,Meng Zhang,Aihua Ran,Xuan Zhang,Feiyu Kang,Guodan Wei
Nowadays, nearly 48.7% near-infrared (NIR) irradiation (>800 nm) of the full solar spectrum has actually not been fully utilized since the state-of-the-art perovskite film usually can only absorb the most UV–vis sunlight radiation. Herein, high efficiency integrated Cs 0.15 FA 0.85 PbI 3 perovskite/organic bulk (PC 61 BM:D18:Y6) heterojunction solar cells with enhanced low energy photon harvest until 931 nm and a high maintained open circuit voltage of 1.04 V is successfully obtained. In particular, the favorable double cascading charge transfer paths pave an interesting possibility to spatially separate electrons upon visible light excitation and holes upon NIR photon absorption simultaneously at interfaces, significantly suppressing non-radiative bimolecular recombination and reaching the photocurrent density as high as 27.48 mA cm −2 and power conversion efficiency of 20.31%. Besides, the strong hydrophobicity of the ternary organic film has effectively prevented ambient humidity penetration and improves the stability of the perovskite in the continuous aging test (humidity > 60%) compared with the control device. This work has opened a significantly new window to improve the NIR light harvest for next generation highly efficient solar cells with full spectrum response.
研究领域:
材料科学
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太阳能电池
·
光伏技术
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有机电子学
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钙钛矿太阳能电池
·
近红外光吸收
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高影响因子
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