SEPARATION AND PURIFICATION TECHNOLOGY
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2024
·
IF 8.1
Hang Cui,Jing Yan,Faguang Ma,Zequan Diao,Ming Yan,Yilin Wu,Jianming Pan
Here, ribavirin (RBV) was introduced into metal organic frameworks (MOFs) in this instance to direct the in situ fabrication of appropriate nanocage structures to facilitate the targeted binding of RBV. Well-designed nano-caged RBV imprinted membranes (NCRIMs) have remarkable antifouling capabilities and can selectively separate RBV from wastewater generated by the RBV production process by constructing imprinting sites inside the molecule. Polydopamine (PDA) is rich in hydrophilic groups (hydroxyl and amino groups) that interact with water molecules via hydrogen bonding, thereby generating a hydrate layer on the membrane surface. The synthesized RBV imprinted sites were homogeneously scattered at the interface and inside of the membrane, resulting in a satisfactory selectivity. Notably, methacrylic acid and acrylamide act as functional monomers that synergistically promote the ability to selectively recognise RBV imprinting sites. It was demonstrated that NCRIMs had favourable rebinding selectivity ( α RBV/ACV = 3.28, α RBV/AZT = 2.48, α RBV/LAM = 3.72) as well as partial selectivity ( β RBV /LAM = 9.48, β RBV/AZT = 8.20, β RBV/ACV = 2.95), indicating the potential of NCRIMs in practical application. What is significant is that the cooperative imprinting and modification methods devised in this study offer directions for the selective isolation of valuable components from complex environments, as well as a reference towards the design of potentially highly resistant membranes.
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Chemosensors
·
2024
·Vol. 12
·期 3
·39
·
IF 3.7
Yu Zhang,Chang Liu,Rongqiu Yan,Chenghong Lei
Bipyridyl Ruthenium-decorated Ni-MOFs on multi-walled carbon nanotubes (MWCNT-RuBpy@Ni-MOF) were synthesized. In an alkaline solution, the glucose was electrocatalytically oxidized at +0.5 V vs. Ag/AgCl at the composite interface of MWCNT-RuBpy@Ni-MOF on a glassy carbon electrode. The Ni3+/Ni2+redox couples in Ni-MOFs played a key role as the active center for the catalytic oxidation of glucose at the electrode, where both RuBpy and MWCNTs enhanced the current responses to glucose. The resulting enzymeless glucose sensor from MWCNT-RuBpy@Ni-MOF exhibited a wide range of linear responses, high sensitivity and selectivity for the determination of glucose.
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CHEMICAL PHYSICS LETTERS
·
2024
·
IF 2.8
Xueying Wang,Qian Ma,Yi Wang,Lingyu Li,Dongheng Zhao,Huayushuo Zhang,Bolong Li
Bimetallic MOFs-derived hierarchical WO 3 /ZnWO 4 /CoWO 4 heterostructures were prepared by electrospinning for achieving superior n-butanol-sensing property at low operating temperatures. Porous chain-like structures can gradually transformed into porous mulberry-like structures composed of various accumulated particles as increasing the additive amount of Zn/Co-ZIFs. High selectivity and stability of WO 3 -based composites to 100 ppm n-butanol can be observed at 25 °C, including the large sensitivity of 32 and the fast response/recovery times of 115/179 s. The enhanced gas-sensing performance is primarily ascribed to the increased specific surface area, plentiful polyoxometalate, and effective heterojunctions, obviously promoting surface/interface absorption behavior and electron transport process.
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Journal of Water Process Engineering
·
2024
·
IF 6.3
Huixin Lu,Xiaotian Wang,Tao Deng,Xi Du,Zhenhuan Li,Maliang Zhang
To meet the separation requirements of polyphenylene sulfide (PPS) membranes in extremely harsh environments and to enhance the separation performance of PPS membrane material, this study utilizes Zeolitic imidazolate framework (ZIF) material with a porous structure to modify the structure of the PPS membranes. Using the Contra-diffusion synthesis method, we successfully created PPS composite membranes that were modified by ZIF-8. At the end of the three-hour reaction time, a continuous and dense layer of ZIF-8 crystals with uniform crystal size and regular crystal shape was produced on the matrix membrane's surface. The permeance to rhodamine B aqueous solution is 42.54 L m −2 h −1 bar −1 , and the retention rate is 99.5 %, which has high permeability and retention performance. In the anti-pollution performance test, the composite membrane's flux recovery rate is 72.9 %, which has good anti-pollution performance. After immersion in strong acids, strong alkalis, and a variety of organic solvents, the appearance shows no evident flaws, and the separation performance in strong alkalis and five different types of organic solvents stays steady, demonstrating excellent alkali and solvent resistance. This proves that composite membranes have great potential for application in dye wastewater treatment.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yushan Hou,Yaowei Zhang,Yanyan Huang,Ailing Zhou,Jiatong Han,Kexin Yang,Yiming Zhao,Jie Zhou,Jing Wang,Ge Chen,Xiaomin Xu,Donghui Xu,Jun Lv,Jing Chen,Honghao Lv,Guangyang Liu
The pH-responsive metal–organic framework (MOF) nanocarriers for sustainable controlled release of pesticides is promising in agricultural production owing to their long duration, high loading efficiency and antimicrobial activity. In this work, myclobutanil (MYC) was loaded into an Ag-based MOF (Ag-TCPP), and modified with a metal-phenolic network (MPN) via in-situ polymerization to construct a pH-responsive nano-delivery system (Ag-TCPP@MYC@MPN). Ag-TCPP@MYC@MPN presented a disordered nanoflower structure and many active sites with potential enhanced loading activity. The cumulative release rates of nanoparticles at pH 4.96, 7.5, and 8.5 were 52.6 %, 62.6 % and 80.0 %, respectively. Hence, Ag-TCPP@MYC@MPN has slow release rate and pH responsiveness. The antifungal activity of Ag-TCPP@MYC@MPN was significantly enhanced, and the bacteriostatic rate reached 81.8 %. This enhancement may be attributed to the synergistic antibacterial effect between tannic acid and Ag + . Safety experiments showed the nanoparticles had no inhibitory effect on the germination of Pakchoi seeds, and the pesticide residues of Ag-TCPP@MYC@MPN did not exceed the food safety standards. This work offers a new potential to develop improved responsive stimulus nanocarriers for sustainable controlled release of MYC.
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Biosensors-Basel
·
2024
·Vol. 14
·期 10
·512
·
IF 4.9
Jiawen Fan,Junjie Qi,Jingkun Li,Fuwei Pi
Arginine has been widely applied in the food industry as coloring agents, flavoring agents, and nutritional fortifiers. It is also one of the major components of feed additives. Currently, methods for the highly selective detection of arginine remain absent. For accurate and sensitive detection of L−arginine, a novel ratiometric fluorescence assay based on Ru@UiO-66-NH2was developed and demonstrated in this study. Under optimized detection conditions, the limit of detection (LOD) of this assay for L-arginine was 2.32 μM, which is superior to most assays reported to date. Meanwhile, Ru@UiO-66-NH2showed good stability within 30 days, demonstrating the wide applicability of the proposed assay. The spike-and-recovery rates of the proposed assay for L-arginine in real samples (e.g., tea, grape juice, and serum) were 84.27–113.09%. Overall, the proposed assay showed high sensitivity, good reproducibility, and excellent stability in the detection of L-arginine in both buffer and real samples.
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MATERIALS CHEMISTRY AND PHYSICS
·
2024
·
IF 4.3
Zitao Yan,Tianyang Zhao,Xiaokang He,Yong Pu,Dachuan Zhu
A series of bimetallic-organic frameworks (Eu 1-x Tb x -BTC) have been prepared via solvothermal method by using 1,3,5-benzenetricarboxylic acid as organic ligand, and confirmed by XRD patterns and FT-IR spectra. As x climbs up, the morphology of Eu 1-x Tb x -BTC evolves from micro-sticks gradually to microspheres with the diameter about 2–3 μm, among which Eu 0.1 Tb 0.9 -BTC displays the best luminescence performance under the excitation at 295 nm. Both the emission peaks located at 618 nm and 547 nm are rising with test temperature increasing instead of intrinsic thermal quenching. The fluorescence intensity ratio Δ of Eu 0.1 Tb 0.9 -BTC demonstrates a good linear fit in range of 293 K–473 K, combined with the maximum relative sensitivity ( Sr ) of 0.135%K −1 (293 K) and the temperature resolution ( δT ) range of 0.099 K–0.123 K. Finally, the five-cycle temperature sensing test proves Eu 0.1 Tb 0.9 -BTC has a reliable cycling and thermal stability.
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Results in Chemistry
·
2025
·
IF 4.2
Fuhua Wei,Peng Chen,Qinhui Ren,Qin Zhang,Wei Shang,Diaodiao Zhang,Min Li,Zhao Liang
The Co/Zn-MOFs material was synthesized successfully via the solvothermal method and then underwent calcination at 900 °C. To investigate its structural properties, multiple characterization techniques were applied, such as scanning electron microscopy (SEM), Fourier-transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), and nitrogen adsorption-desorption isotherms. These analyses aimed to assess the features of the carbon material for its efficacy in minocycline removal. The experimental findings demonstrated that the ideal conditions for maximizing minocycline adsorption on the carbon material obtained from Co/Zn-MOFs comprised a dosage of 20 mg, a solution concentration of 50 ppm, and a pH level of 10. Furthermore, kinetic studies revealed that the pseudo-second-order model accurately represented the experimental data. In conclusion, this research underscores the remarkable adsorption capability of the carbon material derived from Co/Zn-MOFs for minocycline, indicating potential applications in environmental cleanup and presenting an innovative approach for environmental preservation.
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ChemistrySelect
·
2025
·Vol. 10
·期 33
·e03026
·
IF 2
Yongzhao Zhang,Yunlei Zhou,Jiahang Wang,Heng Ban,Rongjie Xu,Junhao Pan,Fusheng Ge,Zhenya Zhu,Luping Lyu
Graphical MOFs-templated MgO/ZrO 2 enable highly selective glucose-to-fructose conversion. Structural confinement suppresses MgO agglomeration and tunes basicity, achieving 38.4% yield with 90.9% selectivity. High-selectivity glucose isomerization to fructose is essential for the biorefinery industry and fructose syrup production. In this work, a catalyst with tailored basicity was synthesized via the calcination of a MOFs (metal-organic frameworks)-based composite and employed as a chemo-catalyst for glucose isomerization, achieving high fructose selectivity. Characterization results confirmed that the synthesized catalyst was a composite consisting of and MgO, with MgO highly dispersed within the channels of . The MOFs templating effect restricted particle size and minimized agglomeration of MgO particles, enhancing the interaction between MgO and . This strong interaction effectively modulated the basicity of the catalyst, resulting in the predominance of weak basic sites. As a result, the catalyst demonstrated superior performance in glucose isomerization, achieving a 38.4% fructose yield with 90.9% selectivity at a 10 wt% glucose concentration, outperforming catalysts prepared by conventional methods. However, leaching remains a challenge. This work presents a novel approach for synthesizing highly dispersed mixed oxides and provides an effective catalyst for glucose isomerization.
研究领域:
催化
·
材料科学
·
化学工程
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绿色化学
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生物炼制技术
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RSC Advances
·
2022
·Vol. 12
·期 38
·24670-24680
·
IF 4.036
Wei Qin,Along Yu,Xue Han,Junwei Wang,Jiayin Sun,Jianli Zhang,Yaqing Weng
With the increasing demand for rare earth elements (REEs) due to their wide application in high technology, their recovery and separation from waste sources has gradually come onto the agenda. Herein, a new kind of MIL-101-NH2 (M1N) MOF functionalized with diethanol anhydride (DGA) incorporated into a polyvinylidene fluoride (PVDF) membrane (DGA-M1N@PVDF) has been fabricated for the sorption of REEs from a simulated acid leaching solution of waste phosphor, which contains a large amount of REEs. FTIR, TGA, XRD, fluorescence spectra and XPS analysis were used to characterize the synthesized composite membrane. Batch tests were employed to determine the optimal sorption conditions for Y and Eu adsorbed on DGA-M1N@PVDF adsorbent, such as pH (1–5), content of M1N MOFs (0–40 wt%), contact time (10–180 min) and ion concentration (0–20 mg L−1). Maximum adsorption capacities for Y and Eu on DGA-M1N@PVDF reached 991.7 μg g−1 and 98.76 μg g−1 for trace REE solution, respectively. Moreover, a pseudo-second-order kinetic model accurately described the sorption process, and the plotted isothermal data indicated that the Langmuir model was more suitable than the Freundlich model for Y and Eu sorption with monolayer and chemical adsorption. Meanwhile, FTIR and XPS analyses revealed that the Y and Eu adsorption on the DGA-M1N@PVDF composite membrane was mainly caused by the N and O atoms of the –CONH or –COOH groups coordinated with metal ions. Furthermore, after five cycles, the recovery efficiency by DGA-M1N@PVDF for REEs remains above 82% and the XRD patterns were consistent with the original sample, which implied that the DGA-M1N@PVDF membrane has preferable stability, recyclability and good efficiency in REE separation from waste phosphor solutions.
研究领域:
材料科学
·
环境工程
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Nanoscale
·
2022
·Vol. 14
·期 32
·11693-11702
·
IF 8.307
Hao Sun,Jie Dan,Yanmin Liang,Min Li,Junchen Zhuo,Yi Kang,Zehui Su,Qiuping Zhang,Jianlong Wang,Wentao Zhang
The antibacterial strategy using cutting-edge metal–organic framework (MOF)-based nanozymes can effectively solve the problem caused by antibiotic resistance to protect human health and the environment; however it has been significantly limited by the complicated modification method and non-ideal catalytic activity. Herein, we report a facile dimensionality-reduction strategy to improve the catalytic activity of MOF-based nanozymes. By reducing the dimensionality of two-dimensional Co-TCPP(Fe) (Co–Fe NSs) to zero-dimensional Co-TCPP(Fe) (Co–Fe NDs), the peroxidase-like activity of the prepared bimetallic Co–Fe NDs was almost tripled. Consequently, the bimetallic Co–Fe NDs can highly efficiently catalyze the lower-concentration H2O2 into reactive oxygen species (ROS), resulting in a favorable antibacterial effect against methicillin-resistant Staphylococcus aureus (MRSA). Meanwhile, Co–Fe NDs can effectively promote wound healing and water environment disinfection with good biocompatibility. This work reveals the potential of a zero-dimensional bimetallic MOF-based nanozyme in resisting drug-resistant bacteria and holds great promise for future clinical and environmental applications.
研究领域:
生物医学工程
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材料科学
·
微生物学
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ACS Nano
·
2025
·
IF 16
Zhihua Wang,Mingda Han,Yiqiao Wang,Ning Wang,Yilin Yang,Bingru Shao,Qiannan Miao,Zhan Shi,Fei Yan,Shouhua Feng
B-cell lymphoma (BCL) is a hematological malignancy with high heterogeneity and represents an aggressive proliferation of mature B-cells. Despite the initial success of traditional treatments for BCL in clinical trials, a majority of patients eventually develop resistance to therapy and have poor clinical outcomes. Epigenetic dysregulation is a major contributor to the pathogenesis of BCL, and therapies targeting epigenetic pathways is a promising alternative strategy for treating BCL. Herein, we developed a metal–organic framework (MOF)-based nano-sonosensitizer for ultrasound-driven cascade immunotherapy against BCL. The nano-sonosensitizer was synthesized by encapsulating copper complex of the m6A-mRNA demethylase inhibitor into UiO-66-NH2, which possesses a Z-scheme heterostructure and allows efficient electron–hole pair separation for generating reactive oxygen species (ROS) under ultrasound activation. These CuR@UiO66 sonosensitizers were functionalized with mPEG-PO3 and anti-CD19 antibody, and the resulting CRUPPA19 particles could specifically accumulate in the BCL tissue and also target lymphoma cells that infiltrated into the bone marrow. Once internalized, CRUPPA19 could induce intracellular ROS production and apoptosis under ultrasound irradiation. Subsequently, ultrasonic stimulation triggered autophagy-mediated release of Cu and Rhein from CRUPPA19, thereby increasing protein lipoylation and global mRNA methylation, which led to cuproptosis and the transcriptional repression PDL1, respectively. These cascades synergistically induced immunogenic cell death in the tumors and promoted activation of CD8+ T cells, eventually leading to an antilymphoma immune response. CRUPPA19-mediated sono-immunotherapy not only eliminated the primary and metastatic lymphomas but also cleared lymphoma cells from the bone marrow. This study provided an insight into a MOF-based nanoepigenetic therapy platform with ultrasound-triggered cascade amplification for enhanced antihematological tumor immunity.
研究领域:
肿瘤学
·
生物医学工程
·
免疫学
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