RSC Advances
·
2019
·Vol. 9
·期 61
·35372-35383
·
IF 3.049
Fang Wang,Le Xin Song,Yue Teng,Juan Xia,Zhe Yuan Xu,Wei Ping Wang
In this work, a simple one-step hydrothermal method was developed to synthesize high-quality α-Fe2O3 nanoparticles with a snowflake-like microstructure. First, a series of binary supramolecular aggregates were prepared by a non-covalent combination between a polymer such as polyvinylpyrrolidone (PVP) and a complex such as potassium ferrocyanide (PF). Then, the aggregates were used as the precursors of the one-step hydrothermal reactions. The snowflake-like nanostructure has six-fold symmetry as a whole, and each petal is symmetric. This synthesis method has the characteristics of simplicity, rapidity, reliance, and high yield, and can be used for creating high-quality α-Fe2O3 nanoparticles. Moreover, our results show that the molar ratio of PVP to PF, reaction time and temperature play important roles in the generation of a complete snowflake structure from different angles. Also, the snowflake-like α-Fe2O3 nanostructure exhibits a much higher coercivity (2997 Oe) compared to those reported by others, suggesting a strong hysteresis behaviour, which promises potential applications in memory devices, and other fields. Further, the α-Fe2O3 nanosnowflakes show a much higher photocatalytic degradation activity for cationic organic dyes such as crystal violet, rhodamine 6G than for anionic dyes such as methyl orange. A possible photocatalytic mechanism was proposed for explaining the selectivity of the photocatalytic oxidation reaction of organic dyes. We believe that this study provides a direct link among coordination compounds of transition metals, their supramolecular aggregates with polymers, and controlled hydrothermal synthesis of high-quality inorganic metal oxide nanomaterials.
研究领域:
材料科学
·
化学
·
纳米技术
✓ 已验证
DOI
高影响因子
Natural Product Communications
·
2019
·
IF 0.554
Chengyun He,Xiaoling Liu,Junliang Sun
Baicalein is one of the main bioactive compounds in Scutellaria baicalensis. In this study, its inhibitory mechanism against α-glucosidase from Saccharomyces cerevisiae was clarified based on experimental and molecular simulation methods. According to HPLC analysis, the α-glucosidase inhibitory activity of S. baicalensis (IC50, 6.75 ± 0.08 μg mL−1) was superior to that of acarbose (IC50, 2.52 ± 0.12 mg mL−1). The fluorescence results suggested that baicalein could form a complex with α-glucosidase at the molar ratio of 1 under the drive of hydrogen bonding and van der Waals force. Molecular docking showed that baicalein could form hydrogen bonds with Trp391, Arg428, Gly566,and Glu771 of α-glucosidase, and interacted with Phe385, Phe389, Arg387, Glu429, Phe444, Trp789, and Trp710 by hydrophobic force, which coincided with the experimental results. It can be concluded that baicalein is a potential α-glucosidase inhibitor for controlling the postprandial blood glucose level of diabetics.
研究领域:
药理学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
·
2024
·
IF 4.3
Mohan Huang,Kun Zhao,Shuangyan Liu,Ang Bian,Lu Jiang,Dawei He,Jiaqi He,Yongsheng Wang
The design and development of microwave-absorbing materials with excellent performance hold significant importance in both civil and military fields. The combination of magnetic loss materials and dielectric loss materials can achieve complementary performance effects and regulate impedance matching. In this paper, spindle-like α-Fe 2 O 3 was synthesized using MIL-88A as a template, which was then composited with Ti 3 C 2 T x phase possessing excellent electrical conductivity to obtain Fe 2 O 3 /Ti 3 C 2 T x composites. Ti 3 C 2 T x can provide good conductance loss and dipole polarization relaxation, while the incorporation of Fe 2 O 3 between the layers of Ti 3 C 2 T x not only triggers the interfacial polarization effect but also increases layer spacing, thereby enhancing multiple reflection effects. Furthermore, the magnetic-dielectric synergies further optimize the impedance matching. Through the combined action of multiple mechanisms, the Fe 2 O 3 /Ti 3 C 2 T x composites (with a mass ratio of 1:3 for Fe 2 O 3 and Ti 3 C 2 T x ) exhibit a minimum reflection loss of −34 dB and an effective absorption bandwidth of 1.53 GHz at a thickness of 3 mm, as well as an effective absorption bandwidth of 2.805 GHz at a thickness of 1.5 mm. This paper presents a reference strategy for constructing highly efficient microwave absorbers derived from Metal-organic frameworks (MOFs) and MXene based on their outstanding properties.
研究领域:
材料科学
·
电磁学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Xiaoyu Yang,Shanshan Li,Yang Yang,Xurong Huang,Linhui Li,Wenjin Yang,Zhiqing Zhang,Guanghui Shen,Xiaoyan Hou,Qiang Cui,Anjun Chen
In this study, we developed two novel electrochemical sensors for the detection of hydroxy-α-sanshool (HαSS) and hydroxy-(α+β)-sanshool (H(α+β)SS), based on the molecularly imprinted AuNPs/Fe-MOF polymer composites films. The imprinted films were facilely constructed via in situ electrodeposition of gold nanoparticles (AuNPs) on the Fe-MOF coatings, followed by a simple electrochemical polymerization process. The AuNPs/Fe-MOF composites not only enhanced the electroactive surface areas but also improved the conductivity and the stability of the polymerized films. Under optimal conditions, the HαSS sensor demonstrated excellent performance, with a detection range of 1–120 μM and a detection limit of 0.206 μM. The sensor for H(α+β)SS, reported for the first time, exhibited a broad linear range of 0.11–132 μM and accurately detected total HαSS and HβSS, achieving a detection limit of 0.072 μM. Both sensors performed effectively in the detection of HαSS or H(α+β)SS in Zanthoxylum bungeanum Maxim. and its products. The two developed sensors significantly outperform other previously reported sanshool sensors and show previously potential for applications in the Zanthoxylum industry.
研究领域:
食品科学
·
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Waste and Biomass Valorization
·
2024
·
IF 2.6
Chen Ziqian,Gao Xiaoyan,Zhu Yihui,Deng Yuefeng,Wang Jianjun,Yang Chengli,Hu Kaishun,He Guanya,Li Dali
Food waste cuttlebone has the potential as the raw material of carrier for enzyme immobilization. In this study, we presented a method for synthesizing CaCO 3 nanoparticles coated chitosan (nano-CaCO 3 @chitosan) using cuttlebone as the raw material in the deep eutectic solvent of betaine and urea. The yield of nano-CaCO 3 @chitosan was 89.9%. The nano-CaCO 3 @chitosan was used for immobilization of α-amylase. The yield of enzyme protein was 65.6%. The loading of α-amylase on these nanoparticles was 49.1 mg/g. The optimum reaction conditions of the immobilized α-amylase were 80 °C and pH 4.0. The residual activity of the immobilized α-amylase was 82.9% after reused for 10 cycles. The raw materials for preparing nano-CaCO 3 @chitosan were almost from cuttlebone. The nano-CaCO 3 @chitosan was regarded as reassembly of cuttlebone. Therefore, food waste cuttlebone was utilized as bioresource. Graphical
研究领域:
生物技术
·
食品科学
·
酶工程
✓ 已验证
产品关联
DOI
高影响因子
MOLECULES
·
2022
·Vol. 27
·期 3
·1126
·
IF 4.927
Zhong-Lei Meng,Ru-Si Wen,Xiao-Rui Huang,Rong-Xiu Qin,Yi-Ming Hu,Yong-Hong Zhou
We report the use of five alpha-hydroxy acids (citric, tartaric, mandelic, lactic and glycolic acids) as catalysts in the synthesis of terpineol from alpha-pinene. The study found that the hydration rate of pinene was slow when only catalyzed by alpha-hydroxyl acids. Ternary composite catalysts, composed of AHAs, phosphoric acid, and acetic acid, had a good catalytic performance. The reaction step was hydrolysis of the intermediate terpinyl acetate, which yielded terpineol. The optimal reaction conditions were as follows: alpha-pinene, acetic acid, water, citric acid, and phosphoric acid, at a mass ratio of 1:2.5:1:(0.1–0.05):0.05, a reaction temperature of 70 °C, and a reaction time of 12–15 h. The conversion of alpha-pinene was 96%, the content of alpha-terpineol was 46.9%, and the selectivity of alpha-terpineol was 48.1%. In addition, the catalytic performance of monolayer graphene oxide and its composite catalyst with citric acid was studied, with acetic acid used as an additive.Keywords:pinene;terpineol;alpha-hydroxy acids;phosphoric acid;synthesis
研究领域:
有机化学
·
催化
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Jia'ni Gong,Pengfei Bai,Yifu Zhang,Qiushi Wang,Jingjing Sun,Yanyan Liu,Hanmei Jiang,Ziyi Feng,Tao Hu,Changgong Meng
Molybdenum trioxide (MoO 3 ) has been widely studied in the energy storage field due to its various phase states and unique structural advantages. Among them, lamellar α -phase MoO 3 ( α -MoO 3 ) and tunnel-like h -phase MoO 3 ( h- MoO 3 ) have attracted much attention. In this study, we demonstrate that vanadate ion (VO 3 - ) can transform α -MoO 3 (a thermodynamically stable phase) to h -MoO 3 (a metastable phase) by altering the connection of [MoO 6 ] octahedra configurations. h -MoO 3 with VO 3 - inserted (referred to as h -MoO 3 -V) as the cathode material for aqueous zinc ion batteries (AZIBs) exhibits excellent Zn 2+ storage performances. The improvement in electrochemical properties is attributed to the open tunneling structure of the h -MoO 3 -V, which offers more active sites for Zn 2+ (de)intercalation and diffusion. As expected, the Zn// h -MoO 3 -V battery delivers specific capacity of 250 mAh·g −1 at 0.1 A·g −1 and rate capability (73% retention from 0.1 to 1 A·g −1 , 80 cycles), well exceeding those of Zn// h -MoO 3 and Zn// α -MoO 3 batteries. This study demonstrates that the tunneling structure of h -MoO 3 can be modulated by VO 3 - to enhance the electrochemical properties for AZIBs. Furthermore, it provides valuable insights for the synthesis, development and future applications of h -MoO 3 .
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
DOI
PubMed
高影响因子
BIOORGANIC CHEMISTRY
·
2021
·
IF 5.275
Chun-Mei Hu,Wen-Jing Wang,Yuan-Na Ye,Yu Kang,Jing Lin,Pan-Pan Wu,Dong-Li Li,Li-Ping Bai,Xue-Tao Xu,Bao-Qiong Li,Kun Zhang
In this study, twenty novel cinnamic acid magnolol derivatives were synthesized, and screened for their anti-hyperglycemic potential. All synthesized compounds exhibited good to moderate α-glucosidase and α-amylase inhibitory activities with IC 50 values: 5.11 ± 1.46–90.26 ± 1.85 µM and 4.27 ± 1.51–49.28 ± 2.54 µM as compared to the standard acarbose (IC 50 : 255.44 ± 1.89 μM and 80.33 ± 2.95 μM, respectively). Compound 6j showed the strongest inhibitory activity against α-glucosidase (IC 50 = 5.11 ± 1.46 µM) and α-amylase (IC 50 = 4.27 ± 1.51 µM). Kinetic study indicated that compound 6j was reversible and a mixed type inhibitor against α-glucosidase and α-amylase. In silico studies revealed the binding interaction between 6j and two enzymes, respectively. Finally, cells cytotoxicity assay revealed that compound 6j showed low toxicity against 3 T3-L1 cells and HepG2 cells.
研究领域:
药理学
·
药物化学
·
药物发现
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LWT-FOOD SCIENCE AND TECHNOLOGY
·
2018
·
IF 3.129
Fansheng Kong,Zhipeng Su,Lingzhong Zhang,Yaru Qin,Kai Zhang
The potential applications of grape seeds extracts (GSE) have been limited due to low bioavailability, poor water solubility and sensitivity to temperature, light and oxygen. The purpose of this study was to develop and optimize a preparation method to protect GSE with minimal loss of bioactivity when it reaches the target site. The inclusion rate of GSE reached 96.48% under optimized conditions (inclusion temperature of 40 °C, time of 120 min and mixing speed of 600 r/min). The formation of inclusion complexes with sulfobutyl ether-β-cyclodextrin (SBE-β-CD) not only increased the solubility and stability of GSE, but also retained the antidiabetic effect. The half maximal inhibitory concentration (IC 50 ) values of inclusion complex on α-glucosidase and α-amylase were 1.188 ± 0.12 mg/mL and 0.587 ± 0.04 mg/mL, respectively, which were very close to that of acarbose (1.035 ± 0.04 mg/mL and 0.513 ± 0.05 mg/mL, respectively). The results of the study revealed that the inclusion complex of GSE with SBE-β-CD has potential applications in the field of medicine and health products.
研究领域:
药学
·
食品科学
·
生物技术
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2020
·
IF 2.726
Yumei Xiao,Dongning Liu,Cheng Liu,Yongchao Wang,Cuijuan Wang
Curcumin (CCM) is a natural ingredient with anti-cancer activity. However, the application of CCM is limited in clinical medicine due to its high hydrophobicity and low bioavailability. Hence, it is necessary for development of a feasible strategy for efficient drug delivery and cancer cell-selective targeting. In recent years, nano-scaled metal-organic frameworks (NanoMOFs) have received much attention as an attractive drug delivery carrier due to their unique features of their various sizes, adjustable pore structures , high stability, and easy surface modification. Here, we report a novel composite nanomaterial (denoted as ZIF-8&α-lip) for CCM loading by one-pot method. This synthetic method is simple and rapid, and the final product (CCM@ZIF-8&α-lip) can be obtained within 20 min. In addition, the obtained CCM@ZIF-8&α-lip shows greater growth inhibition of HepG2 cells in comparison with CCM@ZIF-8. Therefore, ZIF-8&α-lip can be used as an ideal drug carrier and propose a new strategy to improve nanoMOFs performance for efficient drug delivery.
研究领域:
药学
·
纳米医学
·
肿瘤学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD BIOCHEMISTRY
·
2018
·Vol. 42
·期 5
·e12607
·
IF 1.552
Zaizhi Liu,Mengxia Wei,Guoqiang Cui,Xinyu Yang,Huiyan Gu,Lei Yang
Double experimental designs, Plackett–Burman design coupled with Box–Behnken design, were used to optimize the simultaneous extraction process of arabinogalactan and taxifolin from Larix gmelinii by ultrasonic microwave synergistic extraction (UMSE) method. The optimal extraction conditions were determined with the extraction yields of 223.40 ± 7.82 mg/g for larch arabinogalactan and 125.02 ± 5.30 mg/g for taxifolin. Compared to conventional methods, UMSE method showed the merits of higher extraction efficiency, saving time, and energy. The molar ratio of galactose to arabinose is found to be 6:1 through the monosaccharide composition analysis of larch arabinogalactan. The obtained taxifolin structure was identified by mass spectrometry, Fourier transform infrared spectroscopy, and nuclear magnetic resonance. Interestingly, larch arabinogalactan and taxifolin showed completely opposite influences on α-amylase, α-glycosidase, and pancreatic lipase; it was inferred that larch arabinogalactan could act as an inhibitor while taxifolin as an accelerator. Practical applications In this study, response surface methodology of Plackett–Burman design and Box–Behnken design performed well to obtain the optimal conditions and satisfactory extraction yields for the extraction of arabinogalactan and taxifolin from Larix gmelinii by ultrasonic microwave synergistic extraction method, which could be a good paradigm for the efficient isolation of bioactive substances from plant matrix in the field of separation science. Meanwhile, the results from the evaluation of the effects of two target compounds on activities of α-amylase, α-glycosidase, and pancreatic lipase in vitro revealed that larch arabinogalactan and taxifolin enjoyed the completely opposite influences on the three digestive enzymes, namely larch arabinogalactan could act as an inhibitor while taxifolin an accelerator. These results will facilitate the application of larch arabinogalactan and taxifolin in the food and pharmaceutical industries.
研究领域:
植物化学
·
食品科学
·
药理学
✓ 已验证
产品关联
DOI
高影响因子
CHINESE JOURNAL OF CHEMICAL PHYSICS
·
2016
·Vol. 29
·期 5
·617-622
·
IF 0.496
Tang Wen-wu,Zhang Xing-hua,Zhang Qi,Wang Tie-jun,Ma Long-long
Ni-based catalysts supported on different supports ( α -Al 2 O 3 , γ -Al 2 O 3 , SiO 2 , TiO 2 , and ZrO 2 ) were prepared by impregnation. Effects of supports on catalytic performance were tested using hydrodeoxygenation reaction (HDO) of anisole as model reaction. Ni/ α -Al 2 O 3 was found to be the highest active catalyst for HDO of anisole. Under the optimal conditions, the anisole conversion is 93.25% and the hydrocarbon yield is 90.47%. Catalyst characterization using H 2 -TPD method demonstrates that Ni/ α -Al 2 O 3 catalyst possesses more amount of active metal Ni than those of other investigated catalysts, which can enhance the catalytic activity for hydrogenation. Furthermore, it is found that the Ni/ α -Al 2 O 3 catalyst has excellent repeatability, and the carbon deposited on the surface of catalyst is negligible.
研究领域:
催化化学
·
材料科学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）