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JOURNAL OF CHEMICAL AND ENGINEERING DATA · 2009 · IF 2.063

Solid−Liquid Equilibria in Binary Mixtures of 1,8-Cineole with p-Cymene, β-Pinene, and Camphene

Dongwei Wei,Lishuo Wang,Chao Zhang

Solid−liquid equilibria have been measured for binary mixtures of 1,8-cineole with p-cymene, β-pinene, and camphene, respectively, using differential scanning calorimetry (DSC) over the whole composition concentration range. All three are simple eutectic systems. The eutectic point of the (1,8-cineole (1) + p-cymene (2)) mixture is at 200.0 K and x1 = 0.124, the (1,8-cineole (1) + β-pinene (2)) mixture at 205.6 K and x1 = 0.154, and the (1,8-cineole (1) + camphene (2)) mixture at 251.8 K and x1 = 0.582. An empirical equation of Ott and Goates was used for correlating the experimental data.

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JOURNAL OF CHEMICAL AND ENGINEERING DATA · 2011 · IF 2.089

Liquid−Liquid Equilibria of Water + Pentan-1-ol + 2,6,6-Trimethylbicyclo[3.1.1]hep-2-ene or 6,6-Dimethyl-2-methylenebicyclo[3.1.1]heptane at (293.15, 303.15, 313.15, and 323.15) K

Xuejun Huang,Yao Chen,Changwei Wang,Hui Wang

Mutual solubility data of water + pentan-1-ol and liquid−liquid equilibrium of water + pentan-1-ol +2,6,6-trimethylbicyclo[3.1.1]hep-2-ene (α-pinene) and water + pentan-1-ol + 6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane (β-pinene) have been measured experimentally at (293.15, 303.15, 313.15, and 323.15) K under atmospheric pressure. The estimated uncertainty of phase composition and temperature were about (0.0005 and 0.05) K, respectively. The experimental ternary liquid−liquid equilibrium data have been simultaneously predicted and correlated by the extended and modified UNIQUAC models.

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PEST MANAGEMENT SCIENCE · 2025 · IF 3.8

Behavior-based stratified management: population suppression and invasion front control of Hylurgus ligniperda (Fabricius) in coastal shelterbelt ecosystems

Huanwen Chen,Dan Xie,Zikai Pan,Niya Jia,Junhua Zhou,Qingshan Yang,Jia Yu,Defu Chi

BACKGROUND The red-haired bark beetle (RHB), Hylurgus ligniperda (Fabricius), is a significant invasive pest responsible for widespread mortality in pine forests. Current control methods are largely ineffective and poorly integrated, failing to halt the spread of RHB. This study aimed to develop and validate an integrated management system that leverages the beetle's behavioral patterns and implements stratified management strategies based on the severity of infestation levels. RESULTS We first enhanced trapping efficiency by optimizing key technologies, including trap design, deployment methods, and lure formulations. Building on this foundation, we developed a stratified management plan with the following key measures: in newly colonized stands, a strategy combining benzyl alcohol repellents and optimized lure attractants, along with flight-interception traps, significantly reduced spread, decreasing the proportion of dead trees from 12.5% to 2.6%. In outbreak stands, intensive measures such as stump removal and mass trapping reduced the RHB population density by 99.05%. Additionally, replanting alters stand volatiles, reducing their attractiveness to the beetles. CONCLUSION The stratified management strategy, applied to both newly colonized and outbreak stands of RHB, proved highly effective in suppressing population growth and preventing further dispersal. This approach offers a key technical solution for restoring damaged coastal ecosystems and provides a valuable reference for managing similar invasive pests worldwide. © 2025 Society of Chemical Industry.

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FITOTERAPIA · 2025 · IF 2.6

Screening bioactive compounds from Qianghuo (Notopterygium incisum) volatile oil via COX-2 magnetic ligand fishing

Li Zhang,Hui Wu,Xiaoyuan Li,Xiu Zhang,Hua Li,Huaqiao Tang,Daxuan Tang,Shijing Du,Ya’’ou Liu,Yangfan Tang,Xiaoming Bao,Guoqiang Cheng

Qianghuo (the rhizomes and radixes of Notopterygium incisum Ting ex H.T. chang) is a traditional Chinese medicine, and widely used as an anti-inflammatory, anodyne, antifebrile agent. Qianghuo volatile oil also exhibits the same properties, and the effects are probably related to the inhibition of cyclooxygenase (COX), but its bioactive components are not clear yet. To figure out the bioactive components of Qianghuo volatile oil target to cyclooxygenase-2 (COX-2), a ligand fishing method using immobilized COX-2 magnetic beads (COX-2-MB S ) and gas chromatography–mass spectrometry (GC–MS) were developed to identify the compounds that act on COX-2. Nine ligands, including 3-carene, β-caryophyllene, eucalyptol, α-terpinene, Limonene, δ-terpinene, α-pinene, β-pinene and γ-terpinene, were specifically captured by COX-2-MB S . Among them, 3-carene, β-caryophyllene, and eucalyptol in Qianghuo volatile oil were isolated and confirmed by in vitro inhibition and in vivo anti-inflammatory activity assays as selective inhibitor against COX-2. The IC 50 values were 13.5, 10.1, and 7.6 μM, respectively. Compared with the model, 3-carene, β-caryophyllene, and eucalyptol considerably reduced ear swelling and paw edema. Moreover, 3-carene and eucalyptol significantly decreased the changes of COX-2 expression in RAW264.7 cells activated by LPS. Our study validated that the developed ligand-fishing method using COX-2-MBs coupled with GC–MS can be applied to recognize COX-2 inhibitors in Qianghuo volatile oil. In vitro/vivo assay showed 3-carene and eucalyptol in Qianghuo volatile oil had strong inhibition against COX-2. This study may provide novel methods for discovering active components for volatile oil–based drug development or aromatherapy.

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