COLLOID AND POLYMER SCIENCE
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2014
·Vol. 292
·期 9
·2295-2302
·
IF 2.41
Zhang Rong-li,Sun Jia-di,Luo Jing,Xu Sheng,Liu Xiao-ya
Poly(γ-glutamic acid) (γ-PGA) has been widely used in many applications due to its excellent biodegradability, biocompatibility, and nontoxic properties. In this study, we synthesized a novel photo-sensitive amphiphilic poly(γ-glutamic acid)-graft-7-amino-4-methylcoumarin (AMC-γ-PGA) copolymer, which can self-assemble into nanoparticles (NPs) via solvent exchange method. The resultant AMC-γ-PGA NPs showed sensitivity to UV irradiation, pH, and ionic strength, owing to the presence of coumarin groups and carboxyl groups on the AMC-γ-PGA copolymer. The AMC-γ-PGA NPs were then used as a matrix to entrap hemoglobin (Hb). The obtained Hb@AMC-γ-PGA nanocomposites were cast on the electrode to form a nanocomposite film, which was then photo-crosslinked by UV irradiation to lock and immobilize Hb. Cyclic voltammetry (CV) experiment showed that the Hb@AMC-γ-PGA-nanocomposite-modified electrode exhibited good electrochemical catalytic activity for H 2 O 2 , implying that the AMC-γ-PGA NPs provided a favorable microenvironment for Hb and preserved the bioactivity of Hb. In addition, the leakage of Hb was efficiently avoided with the photo-crosslinking of the AMC-γ-PGA NPs. The biocompatible photo-sensitive AMC-γ-PGA NPs provided an excellent platform for immobilization of Hb on electrode.
研究领域:
材料科学
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生物化学
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电化学
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纳米技术
✓ 已验证
产品关联
DOI
高影响因子
Defence Technology
·
2025
·
IF 5.9
Ping Ye,Weimiao Wang,Xiaodong Li,Zhiqiang Qiao,Changping Guo,Jinjin He,Xu Zhou,Rui Li,Guangcheng Yang,Guoqing Lv
Based on the characteristics of laser-induced surface ignition, energetic photosensitive films show promising potential to meet the ignition requirements of various energetic materials (EMs). In this study, DATNBI/ferric alginate (DI/FeA), DI/cobalt alginate (DI/CoA), and DI/nickel alginate (DI/NiA) films are fabricated by employing sodium alginate (SA) with a three-dimensional network structure as the film matrix, via ionic cross-linking of SA with Fe 3+ , Co 2+ , and Ni 2+ ions. The study demonstrates that the ionic cross-linking enhances the hydrophobic performance of the films, with the water contact angle increasing from 82.1° to 123.5°. Concurrently, the films’ near-infrared (NIR) light absorption improved. Furthermore, transition metal ions facilitate accelerated electron transfer, thereby catalyzing the thermal decomposition of DATNBI. Under 1064 nm laser irradiation, the DI/FeA film exhibits exceptional combustion performance, with an ignition delay time as low as 76 ms. It successfully acts as an NIR laser ignition medium to initiate the self-sustained combustion of CL-20. This study demonstrates the synergistic realization of enhanced hydrophobicity, improved photosensitivity, and promoted catalytic decomposition through microstructural design of the material, providing new insights for the design of additive-free EMs in laser ignition applications.
研究领域:
材料科学
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化学工程
·
光学
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物理化学
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激光技术
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2024
·
IF 6.1
Wenxue Li,Siyuan Chen,Shiwang Xie,Xianmao Lu,Zhou Li,Yujia Lv,Dan Luo
Bacteriorhodopsin is a biological material with excellent photosensitivity properties. It can directly convert optical signals into electrical signals and is widely used in various biosensors. Here, we present a bR-based wearable pH biometer that can be used to monitor wound infection. The mechanism of the pH-sensitive effect of the bR electrode is explained, which generates a transient photovoltage under light irradiation and a negative photovoltage when the lamp is turned off. Since the photoelectric signal of bR is affected by different pH values, the photovoltage is changed by adjusting the pH value. The ratio (Vn/Vp) of negative photovoltage (Vn) to positive photovoltage (Vp) has a good linear relationship (R2 = 0.9911) in the pH range of 4.0–10.0. In vitro experiments using rats as a model confirmed that this wearable pH biometer can monitor pH changes that occur in wound infection.
研究领域:
生物技术
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生物工程
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传感器
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医疗器械
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2022
·
IF 10.383
Huihuang Huang,Yujie Yang,Hongyi Chen,Fanglu Qin,Bin Yu,Ruonan Wang,Qiang Cao,Ti Wang,Qianqian Lin
Antimony sulfide, as a binary chalcogenide, has attracted great attention in the field of optoelectronics in recent years, particularly in photovoltaics, because of its striking merits such as earth elements abundance, excellent stability, chemical versatility, and solution processability. With the rapid development of fabrication techniques and device engineering, the device performance of Sb2S3 solar cells has experienced an unprecedented success. However, photodetectors based on Sb2S3 were barely reported, especially based on the transistor configuration. In this work, we prepared high quality Sb2S3 thin films via a sol–gel method, and Sb2S3 thin films were deposited on zinc–tin oxide based field-effect transistors. Furthermore, an additional electron transport layer was inserted between the Sb2S3 layers and the zinc–tin oxide channels and archived high-performance phototransistors with proper interfacial engineering. The optimized devices exhibited extremely high photosensitivity (106), low dark current (∼10 pA) and noise (∼11 fA Hz–1/2), high detectivity (1 × 1013 Jones), and superior device stability, indicating great potential for next generation solution-processed photodetectors.
研究领域:
光电子学
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材料科学
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半导体器件
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF NUCLEAR MATERIALS
·
2025
·
IF 3.2
Liang Cai,Shurui Shang,Haifeng Xue,Xin Hu,Qiang Qi,Guangna Luo,Yingchun Zhang
Li 2 TiO 3 -Li 4 SiO 4 biphasic ceramic has attracted increasing attention because of its unique advantages for tritium breeding in fusion reaction. To overcome the critical limitations of conventional Li 2 TiO 3 -Li 4 SiO 4 pebbles, particularly their inadequate mechanical strength and low packing density, this work developed high-performance Li 2 TiO 3 -Li 4 SiO 4 cubic units via digital light processing (DLP). The purge gas flow behavior in stacked cubic unit structure was studied by Computational Fluid Dynamics (CFD) method to evaluate its structural characteristics. The photosensitivity and rheological properties of precursor suspension were studied to verify the printing feasibility. Solid loading and sintering process were optimized to yield the defect-free Li 2 TiO 3 -Li 4 SiO 4 cubic unit. The results show that the purge gas had periodic velocity distribution and extremely low pressure drop in the stacked cubic unit structure. Li 2 TiO 3 -Li 2 SiO 3 -Li 2 CO 3 ceramic suspension possessed suitable photosensitivity and thixotropy, and its optimal solid loading was 40 vol%. After sintering at 1100 °C, the Li 2 TiO 3 -Li 4 SiO 4 cubic unit with high relative density (92.8 %TD), high crush load (2000.3 N) and favorable open-pore structure can be prepared. Comparative analyses of Li-based cubic units indicate that the Li 2 TiO 3 -Li 4 SiO 4 cubic unit not only addresses the limitations of single-phase variants but also demonstrates superior intrinsic characteristics, including excellent mechanical& thermomechanical properties and distinct hydrogen isotope release behavior. This work proves the feasibility of Li 2 TiO 3 -Li 4 SiO 4 biphasic strategy and potential of Li 2 TiO 3 -Li 4 SiO 4 cubic units for the future tritium breeding design.
研究领域:
材料科学
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核工程
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增材制造
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陶瓷材料
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聚变能源
✓ 已验证
产品关联
DOI
高影响因子
ACS Nano
·
2025
·
IF 16
Shiqi Lan,Liu Yang,Shi Zhang,Shijian Tian,Xun Ge,Kaixuan Zhang,Li Han,Dong Wang,Mengjie Jiang,Libo Zhang,Yichong Zhang,Xiaokai Pan,Yingdong Wei,Xiaoshuang Chen,Huaizhong Xing,Cheng Guo,Xiaofang Wang,Kai Zhang,Lin Wang
Broadband anisotropic photodetectors show great promise for polarization-sensitive imaging and multispectral optoelectronic systems yet face critical challenges in material anisotropy modulation and broadband sensitivity. Weyl semimetals exhibit giant optical anisotropy and tunable heterojunction band alignment, enabling high-performance anisotropic photodetection. Herein, ultrabroadband PDs based on the NbNiTe2 (niobium nickel telluride), enabled by antenna integration and heterostructure engineering, achieve high sensitivity from visible to Terahertz (THz). Leveraging its topological quantum material properties and antenna integration, NbNiTe2-based PDs demonstrate high responsivity of 5.86 A/W and fast response time of 0.83 μs in the THz regime. Combined with the nonlinear property of the NbNiTe2-based PDs, a heterodyne experiment is developed, demonstrating their potential for multifrequency THz signal detection and applicability in complex signal processing. The NbNiTe2/MoS2 heterostructure engineered PDs exhibit a remarkably specific detectivity (D*) ranging from 1.37 × 1011 to 4.08 × 1011 cm·Hz0.5·W–1 and broad spectral response covering visible to near-infrared (NIR) wavelengths. Meanwhile, these NbNiTe2-based PDs exhibit significant anisotropic properties, a high electrical conductivity anisotropy ratio of 16.9 and an ultrahigh anisotropy ratio of 5.74. These findings can provide a viable pathway for next-generation room-temperature broadband PDs with high sensitivity and anisotropy.
研究领域:
凝聚态物理
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光电子学
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纳米技术
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量子材料
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太赫兹技术
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材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Membranes
·
2022
·Vol. 12
·期 12
·1188
·
IF 4.562
Yu-Ping Zhang,Ning Wang,De-Liang Chen,Yuan Chen,Meng-Jun Chen,Xin-Xin Chen
Water/oil separation from their mixture and emulsion has been a prominent topic in fundamental research and in practical applications. In this work, a smart superhydrophobic membrane (SHP) was obtained by dipping an off-the-shelf laboratory filter paper in an ethanol suspension of trichloro (1H,1H,2H,2H-tridecafluoro-n-octyl) silane, tetraethyl orthosilicate, and titanium dioxide nanoparticles with different dimensions of 20 and 100 nm. The selection of membrane substrates was optimized including different quantitative and quantitative filter papers with different filtration velocity (slow, intermediate, and fast). The as-prepared SHP was demonstrated to be superhydrophobic and photosensitive, which was used in the separation of carbon tetrachloride and water from their mixture and emulsion. Moreover, orderly aligned micropores were formed for the modified superhydrophobic filter papers by using nanosecond laser. Unidirectional penetration was obtained for the UV-irradiated paper with a bored pore in the range of 50–500 μm in the systems of air/water and water/oil. This study may promote the understanding of unidirectional transportation of liquid droplet and facilitate the design of interfacial materials with Janus-type wettability.Keywords:superhydrophobic filter paper;Janus membranes;dip coating;emulation separation;nanosecond laser
研究领域:
材料科学
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环境工程
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化学工程
·
纳米技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF NANOBIOTECHNOLOGY
·
2024
·Vol. 22
·期 1
·1-21
·
IF 10.6
Chen Shang,He Yan,Huang Xin,Shen Yao,Zou Qingshuang,Yang Gun,Fu Li,Liu Quan,Luo Dixian
Tumor-associated macrophages (TAMs) are a promising target for cancer immunotherapy, but delivering therapeutic agents to TAMs within the tumor microenvironment (TME) is challenging. In this study, a photosensitive, dual-targeting nanoparticle system (M.RGD@Cr-CTS-siYTHDF1 NPs) was developed. The structure includes a shell of DSPE-modified RGD peptides targeting integrin receptors on tumor cells and carboxymethyl mannose targeting CD206 receptors on macrophages, with a core of chitosan adsorbing m6A reading protein YTHDF1 siRNA and chromium nanoparticles (Cr NPs). The approach is specifically designed to target TAM and cancer cells, utilizing the photothermal effect of Cr NPs to disrupt the TME and deliver siYTHDF1 to TAM. In experiments with tumor-bearing mice, M.RGD@Cr-CTS-siYTHDF1 NPs, when exposed to laser irradiation, effectively killed tumor cells, disrupted the TME, delivered siYTHDF1 to TAMs, silenced the YTHDF1 gene, and shifted the STAT3-STAT1 equilibrium by reducing STAT3 and enhancing STAT1 expression. This reprogramming of TAMs towards an anti-tumor phenotype led to a pro-immunogenic TME state. The strategy also suppressed immunosuppressive IL-10 production, increased expression of immunostimulatory factors (IL-12 and IFN-γ), boosted CD8 + T cell infiltration and M1-type TAMs, and reduced Tregs and M2-type TAMs within the TME. In conclusion, the dual-targeting M.RGD@Cr-CTS-siYTHDF1 NPs, integrating dual-targeting capabilities with photothermal therapy (PTT) and RNA interference, offer a promising approach for molecular targeted cancer immunotherapy with potential for clinical application. Graphical Abstract
研究领域:
癌症生物学
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纳米技术
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免疫疗法
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分子生物学
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药理学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）