Water
·
2023
·Vol. 16
·期 1
·145
·
IF 3.4
Yanqiu Zhang,Yang Lu,Minrui Sun,Dechang Zeng
In recent years, the excessive use and disordered discharge of antibiotics have had sustained adverse effects on ecological balance and human health. The convenient and effective detection of these “emerging pollutants” has become one of the research hotspots in the environmental field. In this study, a defective UiO-66 material, namely UiO-66-D, was constructed for the sensitive and selective sensing of tetracycline (TC) and moxifloxacin (MXF) in water. By utilizing a modulated synthesis approach with concentrated HCl, stable blue fluorescence at 400 nm was achieved for UiO-66-D. The as-prepared UiO-66-D could conduct the inner filter effect (IFE) within a short time (10 s) when sensing TC and MXF, and the fluorescence of the UiO-66-D was quenched. In particular, when sensing MXF, a ratiometric signal response was generated due to the combined effect of the IFE and the fluorescence of MXF itself. The sensitive and selective detection of TC and MXF using UiO-66-D was free from the interference of common anions and cations in water samples. The detection limit (LOD) for TC was determined to be 70.9 nM (0–115 μM), while for MXF, it was found to be 33.1 nM (0–24 μM). Additionally, UiO-66-D was successfully used to recognize TC and MXF in lake water with good recoveries, demonstrating that UiO-66-D exhibits substantial potential in the recognition of pollutants in environmental waters.
研究领域:
环境科学
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材料科学
·
分析化学
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DOI
高影响因子
Journal of Food Measurement and Characterization
·
2023
·Vol. 17
·期 5
·5360-5370
·
IF 3.4
Wang Wenhui,Yang Zhen-quan,Xiao Lixia,Guan Tianzhu,Gong Xiaojuan,Hu Qin
This work present a highly sensitive fluorescence method for auramine O (AO) detection in food and drug samples based on carbon nanodots (CDs). The AO can effectively diminish the emission of CDs based on an integrated quenching mechanism of inner filter effect (IFE) and dynamic reaction. The CDs were prepared via a one-step hydrothermal method with citric acid and o-phenylenediamine as precursors. The good selectivity and high sensitivity feature of the proposed method for AO detection were validated. The fluorescence signals were linearly correlated with AO concentration over a range of 0.01‒10.0 µM with a detection limit of 36.3 nM was obtained. The proposed method was finally used for AO determination in traditional Chinese medicine, curry power, bean curb and candy samples with high accuracy. The recoveries ranged from 95.5 to 107.2% and relative standard deviations (RSDs) were less than 3.39%. This work provided a new insight and an operational access to AO detection in food and drug colorants monitoring. Thus, the CDs-based sensor demonstrated feasibility of rapid AO detection considering its appealing simplicity, rapidity and high sensitivity features.
研究领域:
分析化学
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食品安全
·
纳米技术
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DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Wen-Juan Wang,Kai-Qi Liu,Jia-Lou Chen,Gang Wang,Feng Li,Yu-Qin Wang,Fen-Ying Kong,Wei Wang,Zhong-Xia Wang
Cancer is currently one of the deadliest diseases in the world. As one of the most common anti-cancer drugs, monitoring the amount of doxorubicin (Dox) with high sensitivity in serum can not only guide the dosage of Dox and minimize their toxicity, but also guarantee the effectiveness of treatment and the safety of patient’s life. Here, a green luminescent probe of the sulfur-enrichment, nitrogen-deficiency carbon nanodots (SCDs) was synthesized by melamine and 3-mercaptopropionic acid as nitrogen-sulfur-oxygen sources. The optical properties and surface functional groups of the SCDs have tremendously changed owing to the enrichment of the sulfur atoms. Interestingly, the SCDs luminescence can be suppressed by Dox through effective inner filter effect, which was permitted to construct high sensing platform for Dox determination. With the help of this mechanism, a wide linear range from 0.1 μM to 300 μM with a low limit of detection of 78.4 nM by utilizing SCDs-based constructed sensing platform were obtained. More importantly, this sensing platform has been successfully used to detect Dox in serum samples, and achieved satisfactory results with the recoveries between 97.7 and 104.2 %. This study conduces to the design of surface sulfur-containing carbon dots and broaden the utilization of functional SCDs in anthraquinone drugs detection.
研究领域:
生物医学
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药物分析
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纳米材料科学
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DOI
高影响因子
APPLIED SPECTROSCOPY
·
2023
·
IF 3.5
Ning-Ning Wu,Lin-Ge Chen,Hai-Bo Wang
A sensitive fluorescent sensor has been developed for the determination of tetracycline (TC) using adenine thymine (AT)-rich single-stranded DNA (ssDNA) templated copper nanoclusters (CuNCs) as a fluorescent probe. Fluorescent ssDNA-CuNCs were synthesized by employing AT-rich ssDNA as templates and ascorbic acid as reducing agents through a facile one-step method. The as-prepared ssDNA-CuNCs exhibited strong fluorescence with a large Stokes shift (240 nm) and stable fluorescence emission. In the presence of TC, the fluorescent intensity of ssDNA-CuNCs was obviously decreased through the inner filter effect, due to the spectral overlapping between ssDNA-CuNCs and TC. Under the optimal conditions, the strategy exhibited sensitive detection of TC with a linear range from 2 nM to 30 μM and with a limit of detection of 0.5 nM. Furthermore, the sensor was successfully applied for the detection of TC in milk samples. Therefore, it provided a simple, rapid, and label-free fluorescent method for TC detection.
研究领域:
分析化学
·
生物传感
·
环境监测
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DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2020
·
IF 4.613
Xin Tan,Pu Zhang,Cuiying Ye,Yuanhong Min,Qianwen Li,Yi Wang
Development of new methods for dopamine (DA) assay has attracted continuous attention because it serves a vital role in clinical treatment of neurological diseases such as depression, schizophrenia, and Parkinson's disease. Herein, we design a carbon dots (CDs)-MnO 2 nanosheets platform for rapid and sensitive detection of DA in pharmaceutical products. The photoluminescence of CDs can be quenched by MnO 2 nanosheets via inner filter effect (IFE) because the absorption of MnO 2 nanosheets fully covered the excitation and emission bands of CDs. However, DA can transform MnO 2 nanosheets into Mn 2+ ions, resulting in the elimination of the IFE and recovery of the photoluminescent signal. This sensing platform shows a selective and sensitive response to DA in the range of 1–30 μM, with a detection limit of 100 nM. The presented IFE-based strategy gives a new insight on development of label-free, selective and sensitive optical methods for drug assay.
研究领域:
分析化学
·
生物医学
·
药物分析
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DOI
高影响因子
ANALYTICAL LETTERS
·
2025
·
IF 1.8
Xiu Qin,Dongling Meng,Yun Zhou,Xueqin Xu,Binglin Lu,Yuling Pan,Zhiyan Chen
We developed a green one-step method using broccoli pedicels to synthesize carbon quantum dots (CQDs) for selective sensing of Sunset Yellow. The analyte quenched the fluorescence of CQDs through its inner filter effect. A straightforward and reliable fluorescence quenching method using CQDs as probes in monitoring Sunset Yellow was established. The approach showed linearity from 0.1 to 50 µM with a 0.08 µM detection limit and performed well in real samples. This fluorescence-based method holds potential for further investigation and widespread adoption in the food industry.
研究领域:
食品科学
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材料科学
·
环境分析
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DOI
高影响因子
ENVIRONMENTAL TECHNOLOGY
·
2024
·
IF 2.2
Yongli Liu,Guobei Ge,Huanjia Liu,Yuxin Wang,Penghui Zhou,Bin Li,Guifen Zhu
2,4,6-Trinitrophenol (TNP) has high explosive risks and biological toxicity, and there has been considerable concern over the determination of TNP. In the present work, fluorescent carbon dots (CDs) stemmed from a green carbon source of pinecone by the facile hydrothermal approach. A novel environment- friendly fluorescent probe was developed to efficiently detect TNP by using the obtained CDs with remarkable fluorescence stability. The fluorescent CDs exhibited obvious excitation dependence with the highest peaks for excitation and emission occurring at 321 and 411 nm, respectively. The fluorescence intensity is significantly reduced by TNP owing to the inner filter effect with the CDs. The probe exhibited good linearity with TNP concentrations in the range of 0.025–20 μg mL−1, and the limit of detection was as low as 8.5 ng mL−1. Additionally, the probe proved successful in sensing TNP quantitatively in actual environmental samples with satisfied recoveries of 95.6–99.6%. The developed fluorescent probe offered an environment-friendly, efficient, rapid, and reliable platform for detecting trace TNP in the environmental field.HighlightsNovel carbon dots were synthesised from green precursors of pineal powder.The highly effective quenching process was put down to the inner filter effect.The as-constructed fluorescent probe was successfully utilised for sensing 2,4,6-trinitrophenol in environmental samples.The proposed method was simple, rapid, efficient, economical, and eco-friendly.
研究领域:
环境科学
·
材料科学
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产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Shen Zhang,Xiao Wang,Yutong Wang,Jiaxu Dong,Yixuan Zhang,Manlin Zhao
Vitamin B12 is a drug that can participate in the production of bone marrow red blood cells, prevention of pernicious anemia and damage to brain nerves. It is needful to prepare new vitamin B12 determination strategies with excellent sensitivity, selectivity and uniqueness. Herein, a novel and facile chemical reduction method was successfully carried out (histidine and ascorbic acid were applied as protectant and reductant) for preparing histidine-functionalized silver nanoclusters (Ag NCs@his) with blue fluorescence. Some technologies were adopted to clarify the structure, optical characteristics of this stable Ag NCs@his and fluorescence quenching mechanism. Based on inner filter effect, a sensitive and selective platform for vitamin B12 detection was established. Under optimum pH value, reaction time and temperature, the as-developed platform could be utilized to the trace measurement of vitamin B12 with linear range of 0.5–200 μM and detection limit of 0.038 μM. Moreover, this platform was successfully used to measure vitamin B12 in real samples and temperature.
研究领域:
生物化学
·
分析化学
·
医学检测
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产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2019
·
IF 3.206
Mai Luo,Jinchao Wei,Yunyang Zhao,Yuzhou Sun,Hengxing Liang,Shuangpeng Wang,Peng Li
Methyl-paraoxon (MP) is a representative organophosphorus pesticide (OP), which is a huge threat to the safety of human beings. In this study, carbon dots doped with boron and nitrogen (B, N–CDs) were used as a fluorescent probe for MP detection. The prepared cerium oxide (CeO 2 ) decompose MP efficiently into p-nitrophenol (p-NP) and phosphate group in the alkaline condition. The dissociative p-NP could reduce the fluorescent intensity of B, N–CDs through the inner filter effect (IFE). The pH value, incubation time, the amount of B, N–CDs and solvent effect were investigated and optimized for detection system. Under the optimum conditions, the limit of the detection was calculated to be 24.7 ng mL −1 with simple procedures. Tap water, lake water, Semen Coicis and Panax quinquefolius L. samples were used to test the recoveries of the detection system. The recoveries ranged from 94.68% to 107.28%. Furthermore, the fluorescence laminate was developed by painting B, N–CDs on the polyamide laminate. The MP residue could be observed directly under the 365 nm lamp, and linearity for MP by using the fluorescent laminates was ranged from 0.015 to 1.5 mM. The present work provides a rapid and dual-signal based method (fluorescent and visual) for routine detection of MP in real samples.
研究领域:
分析化学
·
环境科学
·
食品安全
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DOI
高影响因子
MICROCHIMICA ACTA
·
2017
·Vol. 185
·期 1
·1-6
·
IF 4.58
Mao Mi,Tian Tian,He Yu,Ge Yili,Zhou Jiangang,Song Gongwu
Boron and nitrogen codoped carbon dots functionalized with cyclodextrin (β-CD-N/B-C-dots) were obtained from β-cyclodextrin. The material displays strong fluorescence (with excitation/emission peak wavelengths of 400/500 nm) and was characterized by UV-vis, transmission electron microscopy and FTIR. If the substrate p-nitrophenylphosphate is enzymatically cleaved by alkaline phosphatase (ALP), a yellow product is formed whose absorption overlaps the excitation spectrum of the β-CD-N/B-C-dots. Hence, fluorescence is reduced due to an inner filter effect. In additon, the β-CD cavity offers a pocket for substrate recognition. The findings were used to design a method for the determination of the activity of ALP. It has a working range that extends from 0.003 to 5.5 U·L −1 , with a 0.3 mU·L −1 detection limit. The method is fast, simple, inexpensive, and highly sensitive and selective.
Schematic of an inner filter effect based probe for alkaline phosphatase based on the use boron and nitrogen co-doped carbon dots (N/B-C-dots) modified with β-cyclodextrin (β-CD). PNPP: p-Nitrophenylphosphate; PNP: p-Nitrophenol anion.
研究领域:
生物化学
·
分析化学
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产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2018
·Vol. 10
·期 35
·4251-4256
·
IF 2.073
Wen Jie Zhang,Shi Gang Liu,Lei Han,Yu Ling,Liu Li Liao,Shi Mo,Hong Qun Luo,Nian Bing Li
A facile, low-cost, and effective sensing strategy for detection of picric acid (PA) was developed based on copper nanoclusters (CuNCs). In this strategy, highly fluorescent CuNCs were prepared by using copper nitrate and ascorbic acid through an environmentally friendly process. Also, the PA-induced fluorescence quenching mechanism was investigated through ultraviolet-visible absorption spectra, fluorescence spectra, and fluorescence lifetimes, and might be ascribed to the molecular interactions and the strong inner filter effect between the CuNCs and PA. Under the optimal conditions, the fluorescence quenching degree of as-synthesized CuNCs was linearly dependent on the concentration of PA within a wide linear range of 2–40 μM, and the limit of detection was 0.98 μM. Finally, the proposed method was successfully applied to detect the levels of PA in real water samples.
研究领域:
分析化学
·
环境科学
·
材料科学
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产品关联
DOI
高影响因子
LUMINESCENCE
·
2022
·Vol. 37
·期 6
·868-875
·
IF 2.613
Feifei Li,Pengfei Fan,Xinbei Chen,Xi Lin,Can Liu,Congcong Hu,Shengyuan Yang,Fubing Xiao
Sensitive detection of doxorubicin (DOX) is critical for clinical theranostics. A novel ratiometric fluorescence strategy based on the inner filter effect (IFE) has been established for the sensitive detection of DOX by designing a ratiometric fluorescence probe. In the presence of DOX, the fluorescence intensity of copper nanoclusters (CuNCs) at 485 nm decreases, and the fluorescence intensity of carbon dots at 560 nm increases. Therefore, DOX can be quantitatively detected by measuring the ratio of the fluorescence intensities at 560 and 485 nm ( F 560 / F 485 ). The F 560 / F 485 ratio exhibits a linear correlation with the DOX concentration in the range from 1.0 × 10 −8 M to 1.0 × 10 −4 M with the detection limit of 3.7 nM. Furthermore, this method was also successfully applied to the analysis of DOX in human plasma samples, affording an effective platform for drug safety management.
研究领域:
分析化学
·
生物医学
·
药物分析
✓ 已验证
产品关联
DOI
PubMed
高影响因子
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