BIOSENSORS & BIOELECTRONICS
·
2024
·
IF 10.7
Qiulin Chen,Sheng Li,Xiaoyan Tu,Xinfeng Zhang
The pH of human sweat is highly related with a variety of diseases, whereas the monitoring of sweat pH still remains challenging for ordinary families. In this study, we developed a novel dual-emission Tb-MOF using DPA as the ligand and further designed and constructed a skin-attachable Tb-MOF ratio fluorescent sensor for real-time detection of human sweat pH. With the increased concentration of H + , the interaction of H + with carbonyl organic ligand leads to the collapse of the Tb-MOF crystal structure, resulting in the interruption of antenna effect, and correspondingly increasing the emission of the ligand at 380 nm and decreasing the emission of the central ion Tb 3+ at 544 nm. This Tb-MOF nanoprobe has a good linear response in the pH range of 4.12–7.05 (R 2 = 0.9914) with excellent anti-interference ability. Based on the merits of fast pH response and high sensitivity, the nanoprobe was further used to prepare flexible wearable sensor. The wearable sensor can detect pH in the linear range of 3.50–6.70, which covers the pH range of normal human sweat (4.50–6.50). Subsequently, the storage stability and detection accuracy of the sensors were evaluated. Finally, the sensor has been successfully applied for the detection of pH in actual sweat samples from 21 volunteer and the real-time monitoring of pH variation during movement processing. This skin-attachable Tb-MOF sensor, with the advantages of low cost, visible color change and long shelf-life, is appealing for sweat pH monitoring especially for ordinary families.
研究领域:
生物医学工程
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材料科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2021
·
IF 4.821
Yuanyuan Duan,Yongli Yu,Limei Wang,Shuang Zhao
In this work, a facile method for the preparation of dual-emission lanthanide nanoparticles (NPs) was developed. Tb 3+ -doped LaF 3 NPs coated with 2,6-pyridinedicarboxylic acid (DPA) and Eu 3+ , namely LaF 3 :Tb@DPA-Eu NPs, could produce characteristic emissions of Tb 3+ and Eu 3+ under 272 nm excitation, which originated from the absorption of DPA. The LaF 3 :Tb@DPA-Eu NPs with tunable emission peaks and color could be synthesized by changing the concentration of Eu 3+ . Additionally, the obtained NPs were comprehensively characterized by various analytical methods. Transmission electron microscopy (TEM) images showed that the average size of the NPs was ~15 nm. Moreover, X-ray diffraction (XRD) analysis revealed that the products were single-phase LaF 3 , while the doped Tb 3+ entered the LaF 3 lattice to occupy the La 3+ sites. Owing to their excellent water solubility and good optical properties , the LaF 3 :Tb@DPA-Eu NPs were used as a fluorescence probe for the detection of marbofloxacin (MAR) based on the fluorescence quench. Notably, an effective ratiometric fluorescence method was established. The approach exhibited good sensitivity and selectivity with a linear range of 0.10 ~ 10.0 μM and detection limit of 85 nM. It was successfully employed for the determination of MAR in milk samples with recoveries of 98.1%–106%. Thus, the fluorescence method based on the LaF 3 :Tb@DPA-Eu NPs developed herein provides a convenient and fast platform for the detection of MAR.
研究领域:
分析化学
·
材料科学
✓ 已验证
DOI
高影响因子
Materials Today Nano
·
2022
·
IF 13.364
Waheed Ullah Khan,Ping Zhou,Liying Qin,Abid Alam,Zhangjie Ge,Yuhua Wang
Carbon dots with dual emission have drown increasing attention in biology and medicine due to their fascinating optical and biological properties. Herein, dual emissive nitrogen-doped carbon dots (N-doped CDs) are synthesized by simple annealing of ammonium citrate in the air via solvent-free carbonization . Interestingly, N-doped CDs display dual emission peaking at 462 nm and 560 nm under excitation of 360 nm and 470 nm, respectively. The dual PL emission spectra of the N-doped CDs illustrate that each emission is associated with the single excitation band. The data reveals that two autonomous fluorescent centres are co-existed in N-doped CDs because doping with nitrogen (N) could change the surface chemistry of the CDs. In addition, dual emissive N-doped CDs have significantly low toxicity and could be applied as multicolor cell imaging using T-ca cancer cells. Moreover, obtained N-doped CDs are sensitive to temperature in the range of 15–90 °C and show potential to detect temperature in living cells. Furthermore, low toxicity and high biocompatibility proved that the obtained N-doped CDs could be applied in vivo imaging. Besides, the dual emissive N-doped CDs have the ability to probe Fe 3+ ions in water as well as in living T-ca cells.
研究领域:
材料科学
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生物学
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医学
·
化学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry B
·
2021
·Vol. 9
·期 20
·4111-4119
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IF 6.331
Yi Han,Yanran Liu,Haiguang Zhao,Alberto Vomiero,Ronggui Li
Optical nanothermometers have attracted much attention due to their non-contact and precise measurement with high spatial resolution at the micro- and nanoscales. They can be applied in various fields such as micro-opto-electronics, photonics, and biomedical thermal and pH sensing, while most thermal sensors reported so far contain heavy metals or have low sensitivity. Herein, we demonstrate a highly sensitive ratiometric thermal sensor based on colloidal C-dots. C-dots exhibit dual emission originating from the band gap emission and surface-dominant emission, which show a different temperature-dependent photoluminescence (PL) response. Among different surface-functionalized C-dots, C-dots@OH exhibit an absolute thermal sensitivity of −0.082 °C−1, which is the highest among various types of ratiometric thermosensors, making it a very promising candidate for high-sensitivity, self-calibrated nanoscale thermometry. As a proof-of-concept, C-dots@OH were employed to monitor the intracellular temperature (32–42 °C), showing a clear trend for temperature variation in a single cell, indicating that C-dots could offer a powerful tool for a potential precise measurement of the intracellular temperature. They could also be used as thermal sensors for nano-electronic and optoelectronic devices.
研究领域:
材料科学
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生物医学工程
·
光学
✓ 已验证
DOI
PubMed
高影响因子
NANO
·
2021
·
IF 1.556
Jianliang Bai,Xu Chen,Guojun Yuan,Lu Zhang,Zhujun Huang,Lili Ren
Fluorescent carbon dots (CDs) as a new-type kind of zero-venami material have attracted growing interest. Herein, we developed a novel and convenient method to prepare dual emission nitrogen-doped carbon dots (N-CDs). Under ultraviolet (UV) light, N-CDs show blue and orange fluorescence centered at 435 nm and 595 nm, respectively. Because the two emission peaks of N-CDs exhibit different sensitivity to dopamine (DA), the N-CDs can serve as ratiometric fluorescent probes for DA measurement. The ratio ( I 5 9 5 nm / I 4 3 5 nm ) exhibits good linear relationship with DA concentration within the scope of 45–80 μ M. The quenching mechanism of N-CDs toward DA is also proposed, and it is suggested that the quenching may start because by the electrostatic interaction between N-CDs and DA.
研究领域:
材料科学
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分析化学
·
生物化学
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Xiaoqiong Wang,Hao Guo,Ning Wu,Mengni Xu,Longwen Zhang,Wu Yang
A novel dual-emission ratio fluorescent sensor (N-CDs/R-CDs@ZIF-8) has been constructed successfully by introducing nitrogen-doped blue fluorescence carbon dots (N-CDs) and red fluorescence carbon dots (R-CDs) into the synthetic environment of ZIF-8 by a simple stirring method. The synthesized material not only inherits the excellent optical properties of N-CDs and R-CDs and the strong adsorption and accumulation performance of ZIF-8, but also shows strong fluorescence and structural stability in extreme environments. The presence of Pb 2+ strongly causes the fluorescence quenching of N-CDs, but has almost no effect on the fluorescence of R-CDs. Therefore, a ratio fluorescence sensor is developed for the determination of Pb 2+ . Most importantly, the real-time fluorescence response shows that the composite material has a high selectivity and good sensitivity to Pb 2+ determination, and the calculated LOD is 4.78 nM(S/N = 3) (0.05–50 μM), indicating that the material can be used as a potential fluorescent sensor for Pb 2+ detection.
研究领域:
材料科学
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环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 3
·1-9
·
IF 5.833
Li Yanyue,He Yu,Ge Yili,Song Gongwu,Zhou Jiangang
Green emitting copper nanoclusters (G-Cu NCs), yellow emitting Cu NCs (Y-Cu NCs), orange emitting Cu NCs (O-Cu NCs) and red emitting Cu NCs (R-Cu NCs) were prepared using chicken egg white as the stabilizer by changing the reaction conditions. This is a green, facile and cheap method to explore different color emitting CuNCs by the same precursor and stabilizers. The G-Cu NCs were employed for the detection of ethanol due to their aggregation induced emission enhancement (AIEE) effect. The fluorescence emission of Cu NCs at 526 nm under the excitation of 444 nm can be effectively enhanced in the presence of ethanol due to AIEE effect, thus realizing the quantitative determination of ethanol content in the range 5–60%. In addition, a visual dual-emission fluorescence probe with the combination of G-Cu NCs and silicon nanoparticles (Si NPs/G-Cu NCs) was designed to evaluate ethanol content conveniently and rapidly. Desirable linear relationship is observed between ratio of fluorescence intensity (I 525 /I 441 ) and ethanol content under the excitation of 383 nm. Visible color transformation of this probe is observed in the ethanol content range 2–20%. Moreover, the ethanol sensing platforms were applied to the detection and evaluation of the alcohol content of liquor, and the recoveries in liquor were in the range 99.7% to 113%, broadening the applications of Cu NCs and providing a sensitive detection method for ethanol. Graphical abstract
研究领域:
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
DYES AND PIGMENTS
·
2020
·
IF 4.613
Cheng Zhang,Meilin Liu,Taotao Li,Shengjun Liu,Qian Chen,Jian Zhang,Kui Zhang
In this work, we developed a dual-emission fluorescent carbon dots (CDs) using sodium citrate (SC), triethylenetetramine (TETA) and rose bengal (RB) as raw materials. Under the hydrothermal treatment , the carboxyl group in SC can crosslink with the amino group in TETA to form polymer-like intermediate by amide bond network. The RB molecule, a fluorescein derivative, lost halogen atoms under hydrothermal conditions and integrated with the skeleton structure of the network intermediate. Further dehydration and carbonization resulted in the dual-emission fluorescent CDs. Excited by ultraviolet (UV) light, the CDs exhibited blue and green luminescence centered at 440 nm and 525 nm, respectively. Due to the emission centers of these two colors showed different sensitivity to hypochlorous acid (HClO), we have designed a fluorescence assay to achieve quantitative detection of HClO. Upon addition of different concentrations of HClO to CDs solution in phosphate buffer (pH = 6), the blue emission decreased gradually while the green emission showed only a minimal decrease. By calculating the emission intensity ratio, a good linear relationship was achieved in the range of 0–17 μM, and the limit of detection was as low as 0.75 μM. The results reported here demonstrated a promising way to design organic dye modified CDs for sensing applications.
研究领域:
化学
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分析化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Micro & Nano Letters
·
2018
·Vol. 13
·期 8
·1175-1178
·
IF 0.841
Qiao Cheng,Yu He,Yili Ge,Gongwu Song
In this work, 3-aminophenylboronic acid was used as the starting materials to construct boron and nitrogen co-doped carbon dots with tunable dual-emission intensity at 420 and 540 nm with different excitation at 360 and 500 nm, respectively. The dual-emission carbon dots sensor is employed for rapid and sensitive fluorescence-enhancing detection of Pb 2+ . Compared with previous reported methods, their method showed better linear ranges or detection limits. Under the optimal conditions, the limit of detection of 0.9 nM for Pb 2+ was reached with a wide range of 9 nM to 438 μM. The authors believe that the established method has more opportunities for application for other environmental targets.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2022
·Vol. 414
·期 24
·7253-7263
·
IF 4.478
Mei Xiping,Wang Dongxiu,Wang Songbai,Li Junfen,Dong Chuan
In this paper, intrinsic dual-emission fluorescent carbon dots (CDs) doped with N and S atoms have been firstly fabricated. The characterization results show that CDs are successfully synthesized with two separate fluorescence emissions at 468 nm and 628 nm, respectively. The strong and selective interaction of Cr (VI) ions with CDs lead to obvious fluorescence decrease of CDs at 468 nm, which is caused by a mixed quenching mechanism. At the same time, the fluorescence at 628 nm increase. Interestingly, the CDs solution show obvious color change under the daylight and UV light, so visualization detection of Cr (VI) can be realized in water samples. Based on the data of the emission intensity ratios of F 468 / F 628 , Cr (VI) can be detected from 3.8 to 38.9 μM combined with the linear correlation coefficient of 0.998, and the lowest detection concentration is 47.2 nM. The platform is satisfactorily applied to the detection of Cr (VI) ions in water samples. In addition, the CDs could be applied as fluorescent probes for cell imaging with dual fluorescent emission. Graphical abstract
研究领域:
材料科学
·
分析化学
·
生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 9
·1-12
·
IF 6.408
Yao Chi-Xuan,Yang Lu,Wang Jin,Lv Huan,Ji Xue-Meng,Li Shi-Jie,Liu Jing-Min,Wang Shuo
A straightforward, largely instrument-free, smartphone-based analytical strategy for hexavalent chromium and lysine (Lys) on-site detection via exploitation of dual-emission carbon quantum dots (DECQDs) has been demonstrated. DECQDs show dual-emission peaks at 439 and 630 nm with the excitation at 375 nm. As a dual-mode detection probe, the fluorescence and ultraviolet adsorption spectra of DECQDs vary with hexavalent chromium concentrations. Most importantly, Lys can restore the fluorescence of the hexavalent chromium added DECQD nanoprobe and change the color of the probe under natural light. At the same time, based on the participation of smartphones, the prepared DECQD probes favor the establishment of visual smart sensors that can also be used for the in-situ detection of targets. The on-site quantitative analysis exhibited a linear range of 5.3–320 μM with a detection limit of 1.6 μM towards Cr(VI) and the differentiation of Lys variation from 1 to 75 mM with a detection limit of 0.3 mM. The probe has been applied for the first time to enable vision-based colorimetric in complex samples such as water, milk and egg. The recoveries of Cr(VI) and Lys in real samples were between 90 and 104%, and the relative standard deviation (RSD) was as low as 0.4%. This work offers new perspectives for fundamental understanding and new design of functional luminescent materials that are applicable for food-safety and rapid and intelligent inspection. Graphical abstract A straightforward, large instrument-free, smartphone-based analytical strategy with dual-emission carbon quantum dots was developed for hexavalent chromium and Lys on-site detection via fluorescent and colorimetric twofold readout measure.
研究领域:
分析化学
·
食品安全
·
纳米材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY
·
2023
·
IF 2.6
Junfang Chang,Jie Mao,Yifei Lu,Yalei Liu,Sui Wang
Water-soluble purple fluorescent carbon nanodots (P-CDs) were synthesised using 2-phenylphenol, and red fluorescent carbon dots (R-CDs) were prepared from o-phenylenediamine and phosphoric acid. Based on the fluorescence quenching effect of Ag+ on carbon quantum dots, and additionally introducing a red light-emitting quantum dot with excellent performance and high quantum yield, a dual emission ratiometric fluorescent nanosensor (P-CDs/R-CDs) was established. The semi-quantitative detection of silver ions can be realised. Under the excitation light of 254 nm and 365 nm, the fluorescence spectrum shows double emission fluorescence peaks at 343 nm and 626 nm, which originate from the fluorescence emission of the synthesised C-dots and the additionally introduced C-dots, respectively. The relationship between the ratio of the intensity of the two emission peaks F343/F626 and the concentration of silver ions realises the analysis and detection of silver ions. The linear detection range of this method was 0.096–10 μM, and the detection limit (LOD, S/N = 3) was 32 nM. In addition, the method can also perform naked-eye visual detection according to the fluorescence colour change of the probe under ultraviolet light, and realise the rapid monitoring of Ag+ on site. The P-CDs/R-CDs ratiometric fluorescence sensor provides a new method for the detection of Ag+ and promotes the development of heavy metal ion sensing.
研究领域:
分析化学
·
环境科学
·
纳米材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）