LANGMUIR
·
2025
·
IF 3.9
Hao Yang,Yi Liu,Hao Chen,Hua Li
Marine biofouling is an important factor that affects the service life of marine equipment. In this work, phenol source capsaicin-mimicking N-(4-hydroxy-3-methoxy-benzyl) acrylamide, two amine sources, 3-aminopropyltriethoxysilane (APTES) and furfurylamine (FFA), together with paraformaldehyde were used to prepare two benzoxazine coatings, P(HA) and P(HF). By reaction with iodomethane, the quaternary ammonium group was introduced into the N position of the oxazine ring. Quaternarily ammonified benzoxazine coatings P(HAI) and P(HFI) show exciting antibacterial performance compared to that of the untreated benzoxazine coating. The P(HFI) coating exhibited 93.8%, 96.4%, 99.9%, and 99.9% killing rates for Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Bacillus subtilis, respectively. The quaternary ammonization treatment also precipitated further enhanced anti-alga activity and excellent real-sea antifouling performances. However, the introduction of the ionic groups hindered the thermal polymerization of benzoxazine, leading to more defects on the coating surface, resulting in corrosion resistance that was poorer than that of HA and HF as detected from electrochemical corrosion and neutral salt spray experiments. The corrosion current density of the P(HA) and P(HF) coatings is 2 orders greater than that of the P(HAI) and P(HFI) coatings. Our results shed light on developing new quaternary ammonization treatment routes for polymeric coatings for the desired functions.
研究领域:
材料科学
·
海洋生物学
·
微生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MATERIALS RESEARCH
·
2014
·Vol. 29
·期 11
·1231-1236
·
IF 1.815
Qinhui Chen,Longhui Zheng,Baoling Chen,Junhui He,Haibin Huang,Jinhuo Lin
Groups of chloromethyl were randomly grafted to Janus composite particles and quaternization was carried out on the particles. The Janus material of titania–quaternary ammoniated poly(vinylbenzyl chloride–divinylbenzene) (TiO2–QApoly(VBC–DVB)) was investigated in detail. Results revealed that the anisotropic Janus material containing quaternary ammonium groups was synthesized successfully. The Janus material could be used as the phase transfer catalyst. The catalytic activity of the Janus material was confirmed by the esterification reaction of benzyl chloride and sodium acetate. In the presence of 0.5 wt.% (relative to benzyl chloride) of TiO2–QApoly(VBC–DVB), the esterification yield of benzyl acetate reached 87.6% when the molar ratio of sodium acetate anhydrous to benzyl chloride was 1.2. The catalyst exhibited a high activity and had no obvious loss of activity when recycled three times. Moreover, the Janus material was easily recovered by centrifugation and washed with ethanol and water.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Xiaohui Wei,Junjie Cai,Chunlai Wang,Kun Yang,Sheng Ding,Feng Tian,Song Lin
It is essential to enhance our antibacterial arsenal in the first-aid hemostatic treatment due to the healing delay and even death from the bacteria-contaminated wounds. Herein, serial quaternized chitosan with varying degrees of substitution (QCS X ) was prepared by glycidyl trimethyl ammonium chloride modification. Then the obtained QCS X was conjugated with dialdehyde cellulose (DAC) through Schiff base reaction to obtain the corresponding composite sponges (2QCS X -DAC). The surface morphology, chemical structures, and physical characters of mechanical measurement, water uptake behavior, porosity, and degradation tests were determined. Furthermore, in vitro and in vivo biological assays were performed. The obtained 2QCS X -DAC sponges exhibit abundant porous structures, moderate mechanical properties, excellent water uptake performance, and effective bactericidal rates against Staphylococcus aureus and Escherichia coli . Moreover, these porous composite sponges have superior blood coagulation abilities with the blood coagulation time reduced by 76.6% and 59.8% compared with blank control and Celox™ as well as low hemolysis rates (<5%). Meanwhile, 2QCS 3 -DAC had benign cytotoxicity of L929 cells in vitro and could accelerate the infected wound healing of rats at the early stage in vivo . Overall, this composite sponge appears to be a viable wound dressing for daily wound care in civilian hospitals and emergency hemostasis on battlefields.
研究领域:
生物医学工程
·
材料科学
·
药学
✓ 已验证
DOI
PubMed
高影响因子
POLYMER BULLETIN
·
2020
·Vol. 78
·期 7
·3785-3801
·
IF 2.014
Ma Yu,Wang Lulu,Feng Ruijiang,Wang Jilin,Cai Tianzhou
In this study, we prepared a novel composite membrane (QCS-IRMOF-3) by attaching IRMOF-3 (metal–organic framework materials, formed by coordination of metallic zinc and 2-aminoterephthalic acid) with a free amino group to a quaternized chitosan (QCS) by chemical cross-linking. The successful synthesis of IRMOF-3 was verified by SEM, XRD, and FT-IR. Then, the mechanical properties, swelling properties, ion exchange capacity, hydroxide conductivity and chemical stability of the composite membrane (QCS-IRMOF-3) were also investigated. It was found that the performance of the aforementioned composite membrane was affected obviously by the amount of IRMOF-3 crystals. The composite membrane doped with 15 wt% IRMOF-3 crystals exhibits better overall performance, which included that the tensile strength is 22.4 MPa, water uptake is 78.4%, hydroxide conductivity is 29.9 mS cm −1 at 80 °C, and after immersion in 6.0 mol L −1 KOH solutions at 60 °C for about 240 h, only the conductivity decreased by less than 10%. This result implies that the composite membrane synthesized in this research is promising for application in alkaline polymer electrolyte fuel cells.
研究领域:
材料科学
·
燃料电池技术
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产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2019
·
IF 4.561
Jingyi Ma,Na Liu,Mengen Huang,Limin Wang,Jianwei Han,Hui Qian,Fei Che
As new biomass derived raw material, cardanol has attracted the attention of numerous academic and industrial groups due to its renewability and unique structural features. In this work, seven cardanol-derived quaternary ammonium compounds (QACs) were synthetized with their physicochemical properties and antimicrobial ability evaluated. The surface tension was measured in aqueous medium by the platinum ring method, 2b has the optimal surface activities, which is considerably better than commercialized QAC product cetyltrimethylammonium bromide . Both broth dilution method and agar dilution method were used to obtain the MIC and MBC values of the targeted QACs. 1a , 1b , 2b inhibit the tested bacterial at a concentration of 32 μg/mL. Scanning electron microscopy (SEM) results intuitively showed that the QACs could interact with the bacterial cell membrane, for disrupting the integrity of the membrane. Meanwhile, it was found that the antimicrobial activity depended not only on the alkyl chain length, but also on the CMC value. To sum, seven cardanol-derived QACs were synthetized easily, which showed excellent surface activities and antimicrobial activity, as a promising alternative to the existing fossil fuel derived cationic surfactants and antiseptics.
研究领域:
化学
·
生物学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2016
·
IF 4.035
Qiming Zhao,Shuchao Wu,Peimin Zhang,Yan Zhu
Monodisperse carbonaceous spheres produced by the hydrothermal carbonization of sucrose were first applied as green stationary phase for ion chromatography after quaternization . Depending on the polycondensation of methylamine and 1,4-butanediol diglycidyl ether, polymer containing quaternary ammonium groups were facilely grafted onto the surfaces of hydrothermal carbonaceous spheres (HCSs). The quaternized HCSs with different number of polyelectrolyte layers were characterized by scanning electron microscopy, brunauer-emmett-teller, fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, thermogravimetric analysis and elemental analysis . The measurements of breakthrough curves demonstrated that more layers of grafted polyelectrolyte resulted in higher anion exchange capacity of stationary phase. With good stability, common inorganic anions , monocarboxylic acids , polarizable anions and carbohydrates were effectively separated on the stationary phases, respectively. The high hydrophilicity of HCS surface afforded excellent peak symmetry for all analytes. Furthermore, high-capacity HCSs stationary phase was successfully applied to detect fluoride in tea samples.
研究领域:
分析化学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 76
·61742-61751
·
IF 3.84
Li Qun Xu,Ning Ning Li,Jiu Cun Chen,Guo Dong Fu,En-Tang Kang
Polymeric quaternary ammonium salts (QAS) have been widely studied for their antimicrobial activities. However, most of them were evaluated and used in solution form, which may limit their other applications, in medical and wound care and surface biofouling prevention. The development of antibacterial agents for use both in solution and in surface biofouling prevention are highly interesting and desirable. In this work, quaternized poly(2-(dimethylamino)ethyl methacrylate)-grafted agarose (Agr-g-QPDMAEMA) copolymers were synthesized via a combination of atom transfer radical polymerization (ATRP) and quaternization of tertiary amine moieties. The resulting Agr-g-QPDMAEMA copolymers can be dissolved in aqueous media at low concentrations to evaluate their antibacterial activity in the solution form. They can also be gelated as hydrogels on substrate surfaces to inhibit bacterial adhesion, biofilm formation and bacterial colonization. The Agr-g-QPDMAEMA copolymer hydrogels can be further fabricated into antibacterial patches to inhibit the bacteria growth on the contaminated surfaces.
研究领域:
材料科学
·
微生物学
·
医学工程
✓ 已验证
产品关联
DOI
高影响因子
MATERIALS & DESIGN
·
2018
·
IF 4.525
Yafei Xiao,Wenjuan Huang,Kaijun Xu,Mingxin Li,Minmin Fan,Ke Wang
A series of anion exchange membranes (AEMs) consisting of polyvinyl alcohol/branched polyethyleneimine (PVA/BPEI) were simply prepared by casting method using glutaraldehyde (GA) as crosslinking agent, then quaternized with benzyl chloride and alkalized in KOH solution. Subsequently, the comparative analysis was performed to select the optimal ratio of PVA to BPEI and crosslinking degree of AEMs. The structure and properties of AEMs were verified by FT-IR, XRD, TGA, mechanical analysis, water uptake test, swelling ratio test, ion exchange capacity (IEC) test, ionic conductivity measurement, and alkaline/oxidative stability test. The results showed that the maximum value of ionic conductivity was 86.0 mS/cm at 80 °C with IEC value of 2.35 meq/g. Moreover, the AEM had excellent chemical stability, as the ionic conductivity decreased by <15% in 1 M KOH at 80 °C for 7 days. These results indicated that polyethyleneimine is a promising raw material for the preparation of alkaline anion-exchange membranes used in fuel cell.
研究领域:
材料科学
·
化学工程
·
燃料电池技术
✓ 已验证
产品关联
DOI
高影响因子
Polymers
·
2021
·Vol. 13
·期 21
·3777
·
IF 4.329
Han Wu,Jing Li,Yule Wu,Hui Gao,Ying Guan
For the high-value utilization of hemicellulose-based composite films, the poor film-forming and mechanical properties of hemicellulose-based composite films must be surmounted crucially. Based on this, hemicellulose-based organic-inorganic composite films with good mechanical properties were prepared from quaternized hemicelluloses (QH), bentonite, and polyethyleneimine (PEI). The QH/PEI/bentonite composite films were prepared by vacuum filtration, and the properties of the composite film were investigated. The results showed that the QH was inserted into bentonite nanosheets through hydrogen bonding and electrostatic interactions. PEI was cross-linked with hemicellulose by hydroxyl groups, electrostatically attracted by the bentonite flake layers. The mechanical properties of the composite films were significantly increased by the incorporation of PEI. When the PEI content was 20%, the tensile stress of the composite film was increased by 155.18%, and the maximum tensile stress was reached 80.52 MPa. The composite films had strong UV absorption ability with the transmittance was almost 0 in the UV region from 200 to 300 nm. The thermal property of composite film was also improved, and the residual mass increased by three times compared to QH. These results provide a theoretical basis for the use of hemicellulose-based composite films in packaging applications.Keywords:quaternized hemicelluloses;bentonite;polyethyleneimine;composite films;mechanical property
研究领域:
材料科学
·
生物质利用
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产品关联
DOI
PubMed
高影响因子
CELLULOSE
·
2018
·Vol. 26
·期 3
·1683-1701
·
IF 3.809
Ru Jing,Tong Congcong,Chen Ning,Shan Pengjia,Zhao Xingke,Liu Xuying,Chen Jinzhou,Li Qian,Liu Xiaohuan,Liu Hongzhi,Zhao Ying
Abstract In this work, quaternized nanofibrillated cellulose (Q-NFC) was isolated from bamboo bleached kraft pulp through the pre-treatment using 2, 3-epoxy-propyltrimethylammonium chloride (EPTAC) in an aqueous alkaline media and subsequent high-pressure homogenization. A series of aqueous Q-NFC dispersions with different contents of positively charged trimethylammonium groups on the surfaces of fibrils were obtained. With the amount of added EPTAC increased, the solid recovery ratio, surface charge contents, zeta potential values, and extent of nanofibrillation gradually increased for the as-obtained Q-NFCs. TEM images of Q-NFCs revealed that the incorporation of quaternary ammonium groups contributed to the defibrillation into finer nanofibrils with more uniform width distribution. With an increase in the positive charge contents, both degree of polymerization and decomposition temperature of the Q-NFC films decreased slowly. Steady-state rheological result demonstrated that the maximum shear viscosity was achieved for the Q-NFC0.6 dispersion with the medium charge content. The Q-NFC films with higher charge content displayed superior transparency and tensile strength. Furthermore, the oxygen transmission rate of PLA films was remarkably decreased dramatically from 216.0 to 10.3 mL m −2 day −1 after laminating a thin layer of Q-NFC0.6 on the one side. As compared to TEMPO-oxidized NFC from the same pulp, the surface-charged Q-NFC exhibited higher optical transmittance, shear viscosity, and thermal stability as well as comparable oxygen-barrier properties. Graphical abstract
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2019
·
IF 8.355
Meng-Meng Pan,Qinying Li,Li Xu
Perfluoroalkyl acids (PFAAs) are persistent organic pollutants and it should be removed from the environment before they reach public for water consumption. Herein, the quaternized hierarchically porous polystyrene-divinylbenzene (PS-DVB-N + ) was designed as the adsorbent to remove PFAAs. PS-DVB-N + provided multiple interactions with PFAAs, i.e. hydrophobic, electrostatic and hydrogen interactions, beneficial to enhance the adsorption capacity. Additionally, the multiple interactions could compensate for each other so that relatively stable adsorption performance was expected under different adsorption conditions. Moreover, thanks to hierarchically porous structure of the adsorbent, blockage of adsorbent’s pores by aggregates which were formed at certain PFAAs’ concentrations was inhibited or at least lessened, thus promoting mass transfer and enhancing adsorption efficiency. For the individual four studied PFAAs, adsorption kinetics all well fitted pseudo-second-order model, reaching adsorption equilibrium quickly within 200 min. Particularly, the four studied PFAAs were competitively adsorbed. Perfluorooctane sulfonic acid and perfluorodecanoic acid were fast adsorbed at the beginning until completely adsorbed; adsorption of perfluorooctanoic acid and perfluoroheptanoic acid then took place if the enough adsorbent was available. Besides, PS-DVB-N + was conveniently regenerated for repetitive usages. This study proposed an efficient adsorbent towards PFAAs with large adsorption capacity, fast adsorption rate and good resistance to the adsorption condition, which was potential for real applications.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF INORGANIC BIOCHEMISTRY
·
2023
·
IF 3.9
Songtai Gao,Yujun Sun,Zhong Lu,Nan Jiang,Huaiying Yao
Antibiotics overuse and misuse increase the emergence of multidrug-resistant bacterial strains , which often leads to the failure of conventional antibiotic therapies. Even worse, the tendency of bacteria to form biofilms further increases the therapeutic difficulty, because the extracellular matrix prevents the penetration of antibiotics and triggers bacterial tolerance. Therefore, developing novel antibacterial agents or therapeutic strategies with diverse antibacterial mechanisms and destruction of bacteria biofilm is a promising way to combat bacterial infections. In the present study, the combination of quaternary ammonium compound poly(diallyl dimethyl ammonium chloride) (PDDA) with Cu 2+ was screened out to fight common pathogenic Staphylococcus aureus ( S. aureus ) through multi-mechanisms. This combination appeared strong synergistic antibacterial activity , and the fractional inhibitory concentration index was as low as 0.032. The synergistic antibacterial mechanism involved the destruction of the membrane function, generation of intracellular reactive oxygen , and promotion more Cu 2+ into the cytoplasm. Further, the combination of PDDA and Cu 2+ reduced the extracellular polysaccharide matrix, meanwhile killing the bacteria embedded in the biofilm. The biocompatibility study in vitro revealed this combination exhibited low cytotoxicity and hemolysis ratio even at 8 times of minimum bactericidal concentration . This work provides a novel antibacterial agents combination with higher efficiency to fight planktonic and biofilm conditions of S. aureus.
研究领域:
微生物学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）